| Gene Symbol | B4galt6 |
| Entrez Gene ID | 65196 |
| Full Name | beta-1,4-galactosyltransferase 6 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | catalyzes the transfer of galactose from UDP-Gal to glucosylceramide [RGD, Feb 2006]. |
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B4galt6 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following B4galt6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the B4galt6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa42491 Clone ID Related Accession (Same CDS sequence) NM_031740.1 Accession Version NM_031740.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1149bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577116800000 Organism Rattus norvegicus(Norway rat) Product beta-1,4-galactosyltransferase 6 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF048687.1. On Dec 17, 2003 this sequence version replaced XM_346507.1. ##Evidence-Data-START## Transcript exon combination :: AF048687.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141ATGTCTGCGC TCAAGCGGAT GATGCGGGTC TCCAATCGCT CCCTGATCGC CTTCATCTTC
TTCTTCTCCC TCTCCACGTC CTGTCTCTAT TTCATCTATG TGGCTCCAGG CATCGCCAAC
ACATACCTCT TTATGGTACA AGCTAGAGGC ATCATGCTGA GAGAAAATGT GAAAACAATT
GGACACATGA TCAGGCTGTA TACCAATAAA AACACTACGC TCAATGGGAC AGATTATCCC
GAAGGCAATA ATACAAGTGA CTATCTTGTT CAAACAACAA CGTATCTTCC GCAGAACTTC
ACGTATTCAC CGCACCTCCC CTGTCCAGAG AAGCTGCCTT ATATGCGGGG ATTCCTCAGT
GTCAACGTGA GTGAAATCAG CTTTGATGAA GTCCATCAGC TCTTCTCCAA GGACTCGGAG
ATTGAGCCGG GAGGCCACTG GAGGCCCCAG GACTGCAAGC CTAGATGGAA GGTGGCAGTT
CTCATCCCCT TCCGTAACCG CCATGAACAC CTCCCGATCT TTTTCCTGCA CCTGATCCCG
ATGCTCCAGA AACAGAGGCT GGAATTTGCC TTTTATGTCA TCGAACAGAC CGGCACACAA
CCGTTCAATC GTGCCATGCT CTTTAACGTG GGTTTCAAAG AGGCCATGAA GGACAGAGCC
TGGGACTGTG TGATCTTCCA CGACGTGGAT CATCTTCCTG AGAACGATCG GAACTATTAC
GGATGCGGGG AGATGCCGCG GCACTTTGCA GCGAAGCTGG ACAAGTACAT GTACATTCTT
CCTTATAAGG AGTTCTTTGG TGGGGTGAGT GGCCTGACAG TGGAGCAATT TAGGAAGATC
AATGGCTTTC CCAATGCCTT CTGGGGATGG GGAGGAGAGG ATGACGACCT TTGGAACAGA
GTTCACTACT CTGGATACAA TGTAACCCGG CCAGAGGGGG ACTTGGGAAA ATATACATCT
ATTCCCCATC ACCATCGAGG GGAAGTACAA TTTTTAGGAC GGTATAAATT ACTTCGCTAT
TCTAAGGAGC GTCAGTTCAT TGATGGATTG AACAATTTAT TATACACACC CAAAATACTG
GTTGACAGGC TGTATACAAA TATATCTGTA AACCTCATGC CGGAGTTAGC TCCAGTTGAA
GACTATTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_113928.1 CDS 844..1992 Translation 
Target ORF information:
RefSeq Version NM_031740.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus beta-1,4-galactosyltransferase 6 (B4galt6), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031740.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141ATGTCTGCGC TCAAGCGGAT GATGCGGGTC TCCAATCGCT CCCTGATCGC CTTCATCTTC
TTCTTCTCCC TCTCCACGTC CTGTCTCTAT TTCATCTATG TGGCTCCAGG CATCGCCAAC
ACATACCTCT TTATGGTACA AGCTAGAGGC ATCATGCTGA GAGAAAATGT GAAAACAATT
GGACACATGA TCAGGCTGTA TACCAATAAA AACACTACGC TCAATGGGAC AGATTATCCC
GAAGGCAATA ATACAAGTGA CTATCTTGTT CAAACAACAA CGTATCTTCC GCAGAACTTC
ACGTATTCAC CGCACCTCCC CTGTCCAGAG AAGCTGCCTT ATATGCGGGG ATTCCTCAGT
GTCAACGTGA GTGAAATCAG CTTTGATGAA GTCCATCAGC TCTTCTCCAA GGACTCGGAG
ATTGAGCCGG GAGGCCACTG GAGGCCCCAG GACTGCAAGC CTAGATGGAA GGTGGCAGTT
CTCATCCCCT TCCGTAACCG CCATGAACAC CTCCCGATCT TTTTCCTGCA CCTGATCCCG
ATGCTCCAGA AACAGAGGCT GGAATTTGCC TTTTATGTCA TCGAACAGAC CGGCACACAA
CCGTTCAATC GTGCCATGCT CTTTAACGTG GGTTTCAAAG AGGCCATGAA GGACAGAGCC
TGGGACTGTG TGATCTTCCA CGACGTGGAT CATCTTCCTG AGAACGATCG GAACTATTAC
GGATGCGGGG AGATGCCGCG GCACTTTGCA GCGAAGCTGG ACAAGTACAT GTACATTCTT
CCTTATAAGG AGTTCTTTGG TGGGGTGAGT GGCCTGACAG TGGAGCAATT TAGGAAGATC
AATGGCTTTC CCAATGCCTT CTGGGGATGG GGAGGAGAGG ATGACGACCT TTGGAACAGA
GTTCACTACT CTGGATACAA TGTAACCCGG CCAGAGGGGG ACTTGGGAAA ATATACATCT
ATTCCCCATC ACCATCGAGG GGAAGTACAA TTTTTAGGAC GGTATAAATT ACTTCGCTAT
TCTAAGGAGC GTCAGTTCAT TGATGGATTG AACAATTTAT TATACACACC CAAAATACTG
GTTGACAGGC TGTATACAAA TATATCTGTA AACCTCATGC CGGAGTTAGC TCCAGTTGAA
GACTATTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice.
PLoS genetics14(8)e1007545(2018 08)
Yoshihara T,Satake H,Nishie T,Okino N,Hatta T,Otani H,Naruse C,Suzuki H,Sugihara K,Kamimura E,Tokuda N,Furukawa K,Fururkawa K,Ito M,Asano M
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.
Nature medicine20(10)1147-56(2014 Oct)
Mayo L,Trauger SA,Blain M,Nadeau M,Patel B,Alvarez JI,Mascanfroni ID,Yeste A,Kivisäkk P,Kallas K,Ellezam B,Bakshi R,Prat A,Antel JP,Weiner HL,Quintana FJ
Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.
PloS one9(2)e88124(2014)
Yamaji T,Hanada K
β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5.
Glycobiology23(10)1175-83(2013 Oct)
Tokuda N,Numata S,Li X,Nomura T,Takizawa M,Kondo Y,Yamashita Y,Hashimoto N,Kiyono T,Urano T,Furukawa K,Furukawa K
cDNA cloning and expression of human lactosylceramide synthase.
Biochimica et biophysica acta1438(2)301-4(1999 May)
Takizawa M,Nomura T,Wakisaka E,Yoshizuka N,Aoki J,Arai H,Inoue K,Hattori M,Matsuo N
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