| Gene Symbol | Clns1a |
| Entrez Gene ID | 65160 |
| Full Name | chloride nucleotide-sensitive channel 1A |
| Synonyms | Clci,Clcni,Icln,pICln |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | protein involved in cellular chloride transport [RGD, Feb 2006]. |
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Clns1a cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Clns1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clns1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa08577 Clone ID Related Accession (Same CDS sequence) NM_031719.1 , XM_006229792.2 Accession Version NM_031719.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 726bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1573747200000 Organism Rattus norvegicus(Norway rat) Product methylosome subunit pICln Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L26450.1. ##Evidence-Data-START## Transcript exon combination :: L26450.1, BC060555.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721ATGCTTTCGC CCGCAATGAG CTTCCTCAAA AGCTTCCCGC CCCCTGGGTC CGCAGATGGA
CTCCGGCTGC AGCAGCCAGA CACCGAAGCT GTGCTGAACG GGAAGGGGCT CGGCACCGGC
ACGCTTTACA TTGCGGAGAG CCGCCTGTCT TGGCTAGATG GTTCTGGATT AGGATTCTCA
CTGGAGTACC CCACCATTAG TTTACATGCG GTATCCAGGG ACCCAAATGC TTATCCTCAA
GAACATCTGT ATGTCATGGT GAATGCCAGA TTTGGAGAAG AATCAAAAGA ACCTTTCTCT
GATGAAGATG AGGACGACAA TGATGATGTT GAACCCATTT CTGAGTTTAG ATTTGTGCCC
AGTGATAAGT CAGCATTGGA GGCGATGTTC ACAGCAATGT GTGAGTGCCA GGCCCTGCAT
CCAGACCCTG AGGATGAAGA CTCGGATGAC TATGATGGAG AAGAGTATGA TGTGGAAGCA
CATGAGCAAG GACAGGGGGA CATCCCTACA TTTTACACCT ATGAAGAAGG ACTATCCCAT
TTAACAGCAG AAGGGCAAGC CACGCTGGAG AGATTAGAAG GAATGCTTTC TCAGTCTGTG
AGCAGCCAGT ATAATATGGC AGGCGTCCGA ACAGAAGATT CAGTAAGAAC TTACGAAGAT
GGCATGGAGG TAGAGACCAC ACCAACTGTT GCCGGACAGT TCGAGGATGC AGACGTTGAC
CACTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_113907.1 CDS 26..751 Translation 
Target ORF information:
RefSeq Version NM_031719.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus chloride nucleotide-sensitive channel 1A (Clns1a), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031719.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGCTTTCGC CCGCAATGAG CTTCCTCAAA AGCTTCCCGC CCCCTGGGTC CGCAGATGGA
CTCCGGCTGC AGCAGCCAGA CACCGAAGCT GTGCTGAACG GGAAGGGGCT CGGCACCGGC
ACGCTTTACA TTGCGGAGAG CCGCCTGTCT TGGCTAGATG GTTCTGGATT AGGATTCTCA
CTGGAGTACC CCACCATTAG TTTACATGCG GTATCCAGGG ACCCAAATGC TTATCCTCAA
GAACATCTGT ATGTCATGGT GAATGCCAGA TTTGGAGAAG AATCAAAAGA ACCTTTCTCT
GATGAAGATG AGGACGACAA TGATGATGTT GAACCCATTT CTGAGTTTAG ATTTGTGCCC
AGTGATAAGT CAGCATTGGA GGCGATGTTC ACAGCAATGT GTGAGTGCCA GGCCCTGCAT
CCAGACCCTG AGGATGAAGA CTCGGATGAC TATGATGGAG AAGAGTATGA TGTGGAAGCA
CATGAGCAAG GACAGGGGGA CATCCCTACA TTTTACACCT ATGAAGAAGG ACTATCCCAT
TTAACAGCAG AAGGGCAAGC CACGCTGGAG AGATTAGAAG GAATGCTTTC TCAGTCTGTG
AGCAGCCAGT ATAATATGGC AGGCGTCCGA ACAGAAGATT CAGTAAGAAC TTACGAAGAT
GGCATGGAGG TAGAGACCAC ACCAACTGTT GCCGGACAGT TCGAGGATGC AGACGTTGAC
CACTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa08577 Clone ID Related Accession (Same CDS sequence) NM_031719.1 , XM_006229792.2 Accession Version XM_006229792.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 726bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product methylosome subunit pICln isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006229792.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721ATGCTTTCGC CCGCAATGAG CTTCCTCAAA AGCTTCCCGC CCCCTGGGTC CGCAGATGGA
CTCCGGCTGC AGCAGCCAGA CACCGAAGCT GTGCTGAACG GGAAGGGGCT CGGCACCGGC
ACGCTTTACA TTGCGGAGAG CCGCCTGTCT TGGCTAGATG GTTCTGGATT AGGATTCTCA
CTGGAGTACC CCACCATTAG TTTACATGCG GTATCCAGGG ACCCAAATGC TTATCCTCAA
GAACATCTGT ATGTCATGGT GAATGCCAGA TTTGGAGAAG AATCAAAAGA ACCTTTCTCT
GATGAAGATG AGGACGACAA TGATGATGTT GAACCCATTT CTGAGTTTAG ATTTGTGCCC
AGTGATAAGT CAGCATTGGA GGCGATGTTC ACAGCAATGT GTGAGTGCCA GGCCCTGCAT
CCAGACCCTG AGGATGAAGA CTCGGATGAC TATGATGGAG AAGAGTATGA TGTGGAAGCA
CATGAGCAAG GACAGGGGGA CATCCCTACA TTTTACACCT ATGAAGAAGG ACTATCCCAT
TTAACAGCAG AAGGGCAAGC CACGCTGGAG AGATTAGAAG GAATGCTTTC TCAGTCTGTG
AGCAGCCAGT ATAATATGGC AGGCGTCCGA ACAGAAGATT CAGTAAGAAC TTACGAAGAT
GGCATGGAGG TAGAGACCAC ACCAACTGTT GCCGGACAGT TCGAGGATGC AGACGTTGAC
CACTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006229854.1 CDS 89..814 Translation
Target ORF information:
RefSeq Version XM_006229792.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus chloride nucleotide-sensitive channel 1A (Clns1a), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006229792.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGCTTTCGC CCGCAATGAG CTTCCTCAAA AGCTTCCCGC CCCCTGGGTC CGCAGATGGA
CTCCGGCTGC AGCAGCCAGA CACCGAAGCT GTGCTGAACG GGAAGGGGCT CGGCACCGGC
ACGCTTTACA TTGCGGAGAG CCGCCTGTCT TGGCTAGATG GTTCTGGATT AGGATTCTCA
CTGGAGTACC CCACCATTAG TTTACATGCG GTATCCAGGG ACCCAAATGC TTATCCTCAA
GAACATCTGT ATGTCATGGT GAATGCCAGA TTTGGAGAAG AATCAAAAGA ACCTTTCTCT
GATGAAGATG AGGACGACAA TGATGATGTT GAACCCATTT CTGAGTTTAG ATTTGTGCCC
AGTGATAAGT CAGCATTGGA GGCGATGTTC ACAGCAATGT GTGAGTGCCA GGCCCTGCAT
CCAGACCCTG AGGATGAAGA CTCGGATGAC TATGATGGAG AAGAGTATGA TGTGGAAGCA
CATGAGCAAG GACAGGGGGA CATCCCTACA TTTTACACCT ATGAAGAAGG ACTATCCCAT
TTAACAGCAG AAGGGCAAGC CACGCTGGAG AGATTAGAAG GAATGCTTTC TCAGTCTGTG
AGCAGCCAGT ATAATATGGC AGGCGTCCGA ACAGAAGATT CAGTAAGAAC TTACGAAGAT
GGCATGGAGG TAGAGACCAC ACCAACTGTT GCCGGACAGT TCGAGGATGC AGACGTTGAC
CACTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW
RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.
The Journal of biological chemistry286(3)1976-86(2011 Jan)
Guderian G,Peter C,Wiesner J,Sickmann A,Schulze-Osthoff K,Fischer U,Grimmler M
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.
Cell135(3)497-509(2008 Oct)
Chari A,Golas MM,Klingenhäger M,Neuenkirchen N,Sander B,Englbrecht C,Sickmann A,Stark H,Fischer U
Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior.
The Journal of biological chemistry283(29)20408-20(2008 Jul)
Fronz K,Otto S,Kölbel K,Kühn U,Friedrich H,Schierhorn A,Beck-Sickinger AG,Ostareck-Lederer A,Wahle E
ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.
The Journal of biological chemistry280(35)31276-82(2005 Sep)
Fürst J,Schedlbauer A,Gandini R,Garavaglia ML,Saino S,Gschwentner M,Sarg B,Lindner H,Jakab M,Ritter M,Bazzini C,Botta G,Meyer G,Kontaxis G,Tilly BC,Konrat R,Paulmichl M
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