Exoc7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exoc7
Entrez Gene ID	64632
Full Name	exocyst complex component 7
Synonyms	Exo70
General protein information	Preferred Names exocyst complex component 7 Names exocyst complex component 7 exocyst complex component Exo70 rexo70
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1
Summary	putative component of the exocyst complex; involved with the docking of exocytotic vesicles with fusion sites on the plasma membrane [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022691.1	NP_073182.1	exocyst complex component 7

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os04g0685600	NP_001054320.1
Rattus norvegicus (Norway rat)	Exoc7	NP_073182.1
Xenopus tropicalis (tropical clawed frog)	exoc7	NP_001016896.1

Gene Ontology
Bibliography

Related articles in PubMed

The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons.
Lira M, Arancibia D, Orrego PR, Montenegro-Venegas C, Cruz Y, García J, Leal-Ortiz S, Godoy JA, Gundelfinger ED, Inestrosa NC, Garner CC, Zamorano P, Torres VI
Molecular neurobiology56(7)4620-4638(2019 Jul)

Arl13b and the exocyst interact synergistically in ciliogenesis.
Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC
Molecular biology of the cell27(2)308-20(2016 Jan)

The role of Exo70 in vascular smooth muscle cell migration.
Ma W, Wang Y, Yao X, Xu Z, An L, Yin M
Cellular & molecular biology letters2120(2016)

GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic fusion of Rab11- and L1-containing vesicles by releasing exocyst component Exo70.
Fujita A, Koinuma S, Yasuda S, Nagai H, Kamiguchi H, Wada N, Nakamura T
PloS one8(11)e79689(2013)

Exo70 stimulates the Arp2/3 complex for lamellipodia formation and directional cell migration.
Liu J, Zhao Y, Sun Y, He B, Yang C, Svitkina T, Goldman YE, Guo W
Current biology : CB22(16)1510-5(2012 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Exoc7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exoc7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06263	NM_022691.1 Latest version!	Rattus norvegicus exocyst complex component 7 (Exoc7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exoc7 ( NM_022691.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073182.1 Rattus norvegicus exocyst complex component 7 (Exoc7), mRNA.

Price & Availability↑

CloneID	ORa06263
Clone ID Related Accession (Same CDS sequence)	NM_022691.1
Accession Version	NM_022691.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1962bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	exocyst complex component 7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF032667.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF032667.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGATTCCCC CGCAGGAGGC TTCCGCTCGG CGGCGGGAGA TCGAGGACAA GCTGAAGCAG 
GAGGAGGAGA CGCTGTCCTT TATTCGAGAC AGCCTGGAGA AGAGCGACCA GCTCACTAAG 
AACATGGTGT CTATCCTGTC GTCCTTTGAG AGCCGACTCA TGAAGCTGGA GAACTCCATC 
ATCCCTGTGC ACAAGCAGAC AGAGAACCTA CAGAGGCTGC AGGAGAATGT CGAAAAGACC 
TTATCCTGCC TGGACCATGT TATCAGCTAT TACCACGTAG CCAGCGACAC GGAGAAGATC 
ATCAGAGAGG GCCCCACAGG TAGGCTGGAA GAATACCTGG GAAGCATGGC CAAAATCCAG 
AAGGCTGTGG AGTACTTTCA GGACAACAGC CCAGATAGCC CAGAGCTCAA CAAAGTGAAG 
CTGCTGTTTG AGCGGGGGAA GGAGTCCCTG GAATCGGAGT TCCGCAGTCT GATGACCAGG 
CACAGCAAGG TCATCTCCCC TGTGCTCGTC CTGGACCTCA TCAGTGCGGA TGACGAGCTG 
GAGGTCCAGG AGGACGTGGT CCTGGAGCAC CTGCCTGAGA GCGTGCTCCA GGATGTGATC 
CGCATCTCCC GCTGGCTGGT GGAATATGGT CGGAACCAAG ATTTCATGAA TGTCTACTAT 
CAGATCCGCT CTAGCCAGCT GGACCGCTCC ATCAAGGGTC TGAAGGAGCA TTTTCGCAAA 
AGCAGTTCTT CCTCTGGGGT TCCCTACTCC CCCGCCATCC CCAACAAGAG GAAAGACACG 
CCTACCAAGA AGCCCATCAA GCGGCCAGGG AGAGATGACA TGCTGGACGT GGAGACAGAT 
GCCTACATTC ACTGCGTTAG TGCCTTTGTC AGGCTGGCAC AGAGTGAATA CCAGCTGCTG 
ATGGGCATCA TTCCCGAGCA TCACCAGAAG AAAACCTTCG ACTCCTTGAT ACAGGATGCC 
CTAGATGGGC TGATGCTTGA AGGGGAGAAC ATAGTGTCCG CGGCCAGGAA AGCCATCATC 
CGCCATGACT TCTCCACCGT GCTCACCGTC TTCCCCATCC TGCGACACCT CAAGCAGACC 
AAGCCTGAGT TTGACCAGGT GCTCCAGGGC ACAGCAGCCA GCACGAAGAA CAAGCTGCCA 
GGCCTCATCA CCTCCATGGA GACCATTGGG GCCAAAGCTC TAGAAGACTT TGCGGATAAC 
ATCAAGAATG ATCCAGACAA GGAGTACAAC ATGCCTAAAG ATGGCACCGT TCATGAGCTC 
ACAAGCAATG CCATCCTGTT CCTACAGCAG CTTCTGGACT TCCAGGAGAC AGCAGGCGCC 
ATGCTGGCCT CCCAAGAAAC CAGCTCTTCG GCCACCAGCT ACAACTCCGA GTTCAGCAAG 
CGACTGCTGA GTACCTACAT TTGCAAAGTC CTGGGTAACC TGCAGCTGAA CTTGCTAAGC 
AAGTCCAAGG TGTATGAGGA TCCAGCTCTG AGCGCCATCT TCCTACACAA CAACTACAAC 
TACATCCTCA AGTCCCTGGA GAAGTCTGAG CTGATCCAGC TTGTGGCTGT GACCCAGAAG 
ACTGCTGAGC GCTCCTACCG GGAGCACATT GAGCAGCAGA TCCAGACCTA CCAGCGCAGC 
TGGCTAAAGG TGACTGACTA CATCGCAGAG AAGAATCTAC CTGTGTTCCA GCCTGGAGTC 
AAGCTCCGGG ACAAGGAGCG GCAAATGATT AAGGAACGTT TCAAGGGATT CAATGATGGG 
CTCGAAGAAC TGTGCAAGAT TCAGAAGGCC TGGGCCATCC CAGACACGGA GCAGAGGGAC 
AAGATCCGAC AGGCTCAGAA AAGCATCGTC AAGGAGACCT ATGGGGCCTT TCTGCACAGG 
TATAGCAGCG TGCCCTTCAC CAAAAACCCG GAGAAGTACA TCAAGTACCG TGTGGAGCAG 
GTGGGCGACA TGATCGACCG CCTCTTCGAC ACCTCTGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073182.1
CDS	298..2259
Translation	MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVISPVLVLDLISADDELEVQEDVVLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGRDDMLDVETDAYIHCVSAFVRLAQSEYQLLMGIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYNSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKSIVKETYGAFLHRYSSVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA

Target ORF information:

RefSeq Version	NM_022691.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus exocyst complex component 7 (Exoc7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022691.1

ORF Insert Sequence:

ATGATTCCCC CGCAGGAGGC TTCCGCTCGG CGGCGGGAGA TCGAGGACAA GCTGAAGCAG 
GAGGAGGAGA CGCTGTCCTT TATTCGAGAC AGCCTGGAGA AGAGCGACCA GCTCACTAAG 
AACATGGTGT CTATCCTGTC GTCCTTTGAG AGCCGACTCA TGAAGCTGGA GAACTCCATC 
ATCCCTGTGC ACAAGCAGAC AGAGAACCTA CAGAGGCTGC AGGAGAATGT CGAAAAGACC 
TTATCCTGCC TGGACCATGT TATCAGCTAT TACCACGTAG CCAGCGACAC GGAGAAGATC 
ATCAGAGAGG GCCCCACAGG TAGGCTGGAA GAATACCTGG GAAGCATGGC CAAAATCCAG 
AAGGCTGTGG AGTACTTTCA GGACAACAGC CCAGATAGCC CAGAGCTCAA CAAAGTGAAG 
CTGCTGTTTG AGCGGGGGAA GGAGTCCCTG GAATCGGAGT TCCGCAGTCT GATGACCAGG 
CACAGCAAGG TCATCTCCCC TGTGCTCGTC CTGGACCTCA TCAGTGCGGA TGACGAGCTG 
GAGGTCCAGG AGGACGTGGT CCTGGAGCAC CTGCCTGAGA GCGTGCTCCA GGATGTGATC 
CGCATCTCCC GCTGGCTGGT GGAATATGGT CGGAACCAAG ATTTCATGAA TGTCTACTAT 
CAGATCCGCT CTAGCCAGCT GGACCGCTCC ATCAAGGGTC TGAAGGAGCA TTTTCGCAAA 
AGCAGTTCTT CCTCTGGGGT TCCCTACTCC CCCGCCATCC CCAACAAGAG GAAAGACACG 
CCTACCAAGA AGCCCATCAA GCGGCCAGGG AGAGATGACA TGCTGGACGT GGAGACAGAT 
GCCTACATTC ACTGCGTTAG TGCCTTTGTC AGGCTGGCAC AGAGTGAATA CCAGCTGCTG 
ATGGGCATCA TTCCCGAGCA TCACCAGAAG AAAACCTTCG ACTCCTTGAT ACAGGATGCC 
CTAGATGGGC TGATGCTTGA AGGGGAGAAC ATAGTGTCCG CGGCCAGGAA AGCCATCATC 
CGCCATGACT TCTCCACCGT GCTCACCGTC TTCCCCATCC TGCGACACCT CAAGCAGACC 
AAGCCTGAGT TTGACCAGGT GCTCCAGGGC ACAGCAGCCA GCACGAAGAA CAAGCTGCCA 
GGCCTCATCA CCTCCATGGA GACCATTGGG GCCAAAGCTC TAGAAGACTT TGCGGATAAC 
ATCAAGAATG ATCCAGACAA GGAGTACAAC ATGCCTAAAG ATGGCACCGT TCATGAGCTC 
ACAAGCAATG CCATCCTGTT CCTACAGCAG CTTCTGGACT TCCAGGAGAC AGCAGGCGCC 
ATGCTGGCCT CCCAAGAAAC CAGCTCTTCG GCCACCAGCT ACAACTCCGA GTTCAGCAAG 
CGACTGCTGA GTACCTACAT TTGCAAAGTC CTGGGTAACC TGCAGCTGAA CTTGCTAAGC 
AAGTCCAAGG TGTATGAGGA TCCAGCTCTG AGCGCCATCT TCCTACACAA CAACTACAAC 
TACATCCTCA AGTCCCTGGA GAAGTCTGAG CTGATCCAGC TTGTGGCTGT GACCCAGAAG 
ACTGCTGAGC GCTCCTACCG GGAGCACATT GAGCAGCAGA TCCAGACCTA CCAGCGCAGC 
TGGCTAAAGG TGACTGACTA CATCGCAGAG AAGAATCTAC CTGTGTTCCA GCCTGGAGTC 
AAGCTCCGGG ACAAGGAGCG GCAAATGATT AAGGAACGTT TCAAGGGATT CAATGATGGG 
CTCGAAGAAC TGTGCAAGAT TCAGAAGGCC TGGGCCATCC CAGACACGGA GCAGAGGGAC 
AAGATCCGAC AGGCTCAGAA AAGCATCGTC AAGGAGACCT ATGGGGCCTT TCTGCACAGG 
TATAGCAGCG TGCCCTTCAC CAAAAACCCG GAGAAGTACA TCAAGTACCG TGTGGAGCAG 
GTGGGCGACA TGATCGACCG CCTCTTCGAC ACCTCTGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons.
Molecular neurobiology56(7)4620-4638(2019 Jul)
Lira M,Arancibia D,Orrego PR,Montenegro-Venegas C,Cruz Y,García J,Leal-Ortiz S,Godoy JA,Gundelfinger ED,Inestrosa NC,Garner CC,Zamorano P,Torres VI

Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell27(2)308-20(2016 Jan)
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC

The role of Exo70 in vascular smooth muscle cell migration.
Cellular & molecular biology letters2120(2016)
Ma W,Wang Y,Yao X,Xu Z,An L,Yin M

GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic fusion of Rab11- and L1-containing vesicles by releasing exocyst component Exo70.
PloS one8(11)e79689(2013)
Fujita A,Koinuma S,Yasuda S,Nagai H,Kamiguchi H,Wada N,Nakamura T

Exo70 stimulates the Arp2/3 complex for lamellipodia formation and directional cell migration.
Current biology : CB22(16)1510-5(2012 Aug)
Liu J,Zhao Y,Sun Y,He B,Yang C,Svitkina T,Goldman YE,Guo W

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Exoc7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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