Nr4a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nr4a2
Entrez Gene ID	54278
Full Name	nuclear receptor subfamily 4, group A, member 2
Synonyms	Nurr1
General protein information	Preferred Names nuclear receptor subfamily 4, group A, member 2 Names nuclear receptor subfamily 4 group A member 2 NUR-related factor 1 RNR-1 SL-322 nuclear orphan receptor HZF-3 nuclear receptor subfamily 4 group A member 2 variant TINUR nuclear receptor subfamily 4 group A member 2 variant NURR1a nuclear receptor subfamily 4 group A member 2 variant NURR1b nuclear receptor subfamily 4 group A member 2 variant NURR1c nuclear receptor subfamily 4 group A member 2 variant NURR2c nur related protein 1 orphan nuclear receptor NURR1 orphan receptor regenerating liver nuclear receptor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q21
Summary	nuclear receptor and transcription factor; plays a role in development and maintenance of neurons synthesizing the neurotransmitter dopamine [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019328.3	NP_062201.2	nuclear receptor subfamily 4 group A member 2
XM_006234201.3	XP_006234263.1	nuclear receptor subfamily 4 group A member 2 isoform X1
XM_017591997.1	XP_017447486.1	nuclear receptor subfamily 4 group A member 2 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	NR4A2	NP_001069676.1
Xenopus tropicalis (tropical clawed frog)	nr4a2	NP_001093678.1
Homo sapiens (human)	NR4A2	NP_006177.1
Canis lupus familiaris (dog)	NR4A2	XP_535920.2
Danio rerio (zebrafish)	nr4a2a	NP_001106956.1
Pan troglodytes (chimpanzee)	NR4A2	XP_003309349.1
Macaca mulatta (Rhesus monkey)	NR4A2	XP_001086719.1
Mus musculus (house mouse)	Nr4a2	NP_001132981.1
Rattus norvegicus (Norway rat)	Nr4a2	NP_062201.2
Gallus gallus (chicken)	NR4A2	XP_422166.2

Gene Ontology
Bibliography

Related articles in PubMed

Dysregulation of Dopaminergic Regulatory Factors TH, Nurr1, and Pitx3 in the Ventral Tegmental Area Associated with Neuronal Injury Induced by Chronic Morphine Dependence.
Shi W, Zhang Y, Zhao G, Wang S, Zhang G, Ma C, Cong B, Li Y
International journal of molecular sciences20(2)(2019 Jan)

Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
Sun C, Wang Y, Mo M, Song C, Wang X, Chen S, Liu Y
BioMed research international20196843265(2019)

Nurr1 promotes neurogenesis of dopaminergic neuron and represses inflammatory factors in the transwell coculture system of neural stem cells and microglia.
Chen XX, Qian Y, Wang XP, Tang ZW, Xu JT, Lin H, Yang ZY, Song XB, Lu D, Guo JZ, Bian LG, Li Y, Zhou L, Deng XL
CNS neuroscience & therapeutics24(9)790-800(2018 09)

Correlation between Nurr1 expression and drug resistance in the brain of rats with epilepsy.
Li HY, Liu F, Wang HR
European review for medical and pharmacological sciences22(5)1506-1513(2018 03)

Effect of Wnt1 and Wnt5a on the development of dopaminergic neurons, and toxicity induced by combined exposure to paraquat and maneb during gestation and lactation.
Ma J, Huang C, Ma K, Wu YP, Li BX, Sun Y
Molecular medicine reports16(6)9721-9728(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nr4a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nr4a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04426	NM_019328.3 Latest version!	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa04426	XM_017591997.1 Latest version!	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa04426	XM_006234201.3 Latest version!	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nr4a2 ( NM_019328.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062201.2 Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), mRNA.

Price & Availability↑

CloneID	ORa04426
Clone ID Related Accession (Same CDS sequence)	NM_019328.3 , XM_006234201.3 , XM_017591997.1
Accession Version	NM_019328.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	nuclear receptor subfamily 4 group A member 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from L08595.1, DQ092633.1, CB606493.1 and AW534944.1. On Oct 11, 2005 this sequence version replaced NM_019328.2. Sequence Note: This RefSeq record was created using sequences from two different strains, F344 and Sprague-Dawley, because no single transcript from the same strain was available for the full length of the gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L08595.1, U01146.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMN00632259 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062201.2
CDS	112..1908
Translation	MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF

Target ORF information:

RefSeq Version	NM_019328.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019328.3

ORF Insert Sequence:

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr4a2 ( XM_006234201.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234263.1 Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa04426
Clone ID Related Accession (Same CDS sequence)	NM_019328.3 , XM_006234201.3 , XM_017591997.1
Accession Version	XM_006234201.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	nuclear receptor subfamily 4 group A member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234201.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234263.1
CDS	3281..5077
Translation	MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF

Target ORF information:

RefSeq Version	XM_006234201.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234201.3

ORF Insert Sequence:

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr4a2 ( XM_017591997.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447486.1 Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa04426
Clone ID Related Accession (Same CDS sequence)	NM_019328.3 , XM_006234201.3 , XM_017591997.1
Accession Version	XM_017591997.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1797bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	nuclear receptor subfamily 4 group A member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447486.1
CDS	213..2009
Translation	MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF

Target ORF information:

RefSeq Version	XM_017591997.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 4, group A, member 2 (Nr4a2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591997.1

ORF Insert Sequence:

ATGCCTTGTG TTCAGGCGCA GTATGGGTCC TCGCCTCAAG GAGCCAGCCC CGCTTCTCAG 
AGCTACAGTT ACCACTCTTC GGGAGAATAC AGCTCCGATT TCTTAACTCC AGAGTTTGTC 
AAGTTTAGCA TGGACCTCAC CAACACTGAA ATTACTGCCA CCACTTCTCT CCCCAGCTTC 
AGTACCTTTA TGGACAACTA CAGCACAGGC TACGACGTCA AGCCACCTTG CTTGTACCAA 
ATGCCCCTGT CCGGACAGCA GTCCTCCATT AAGGTAGAAG ACATTCAGAT GCACAACTAC 
CAGCAACACA GCCACCTGCC CCCTCAGTCC GAGGAGATGA TGCCACACAG CGGGTCGGTT 
TACTACAAGC CCTCTTCGCC CCCGACACCC AGCACCCCGG GCTTCCAGGT GCAGCATAGC 
CCGATGTGGG ACGATCCGGG CTCCCTTCAC AACTTCCACC AGAACTACGT GGCCACTACG 
CATATGATCG AGCAGAGGAA GACACCTGTC TCCCGCCTTT CACTCTTCTC CTTTAAGCAG 
TCGCCCCCGG GCACTCCTGT GTCTAGCTGC CAGATGCGCT TTGACGGGCC TCTGCACGTC 
CCCATGAACC CGGAGCCCGC GGGCAGCCAC CACGTAGTGG ATGGGCAGAC CTTCGCCGTG 
CCCAATCCCA TTCGCAAGCC GGCATCCATG GGCTTCCCGG GCCTGCAGAT CGGCCACGCG 
TCGCAGTTGC TTGACACGCA GGTGCCCTCG CCGCCGTCCC GGGGCTCTCC CTCCAATGAG 
GGTCTGTGCG CTGTTTGCGG TGACAACGCG GCCTGTCAGC ATTACGGTGT TCGCACTTGT 
GAGGGCTGCA AAGGTTTCTT TAAGCGCACG GTGCAAAAAA ACGCGAAATA TGTGTGTTTA 
GCAAATAAAA ATTGCCCAGT GGATAAGCGC CGCCGAAATC GTTGTCAGTA CTGTCGGTTT 
CAGAAGTGCC TGGCTGTTGG GATGGTTAAA GAAGTGGTTC GCACGGACAG TTTAAAAGGC 
CGGAGAGGTC GTCTACCCTC AAAACCGAAG AGCCCACAGG ATCCCTCTCC CCCCTCACCT 
CCGGTGAGTC TGATCAGTGC CCTCGTCAGA GCCCACGTCG ACTCCAATCC GGCAATGACC 
AGCCTGGACT ATTCCAGGTT CCAGGCAAAC CCTGACTATC AGATGAGTGG AGATGATACT 
CAACATATCC AGCAGTTCTA CGATCTCCTG ACTGGCTCTA TGGAGATCAT CAGAGGGTGG 
GCAGAGAAGA TTCCTGGCTT TGCTGACCTG CCCAAAGCCG ATCAGGACCT GCTTTTTGAA 
TCAGCTTTCT TAGAATTATT TGTTCTACGC TTAGCATACA GGTCCAACCC AGTGGAGGGT 
AAACTCATCT TTTGCAATGG GGTGGTCTTG CACAGGTTGC AATGCGTGCG TGGCTTTGGG 
GAATGGATTG ATTCCATTGT TGAATTCTCC TCCAACTTGC AGAATATGAA CATCGACATT 
TCTGCCTTCT CCTGCATTGC TGCCCTGGCT ATGGTCACAG AGAGACACGG GCTCAAGGAA 
CCCAAGAGAG TGGAAGAGCT ACAAAACAAA ATTGTAAATT GTCTTAAAGA CCATGTGACT 
TTCAATAATG GGGGATTGAA CCGACCCAAC TACCTGTCCA AACTGTTGGG GAAGCTCCCA 
GAACTTCGCA CCCTTTGCAC ACAGGGGCTC CAGCGCATTT TCTACCTGAA ATTGGAAGAC 
TTGGTACCAC CACCAGCAAT AATTGACAAA CTTTTCCTGG ACACCTTACC TTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dysregulation of Dopaminergic Regulatory Factors TH, Nurr1, and Pitx3 in the Ventral Tegmental Area Associated with Neuronal Injury Induced by Chronic Morphine Dependence.
International journal of molecular sciences20(2)(2019 Jan)
Shi W,Zhang Y,Zhao G,Wang S,Zhang G,Ma C,Cong B,Li Y

Minocycline Protects against Rotenone-Induced Neurotoxicity Correlating with Upregulation of Nurr1 in a Parkinson's Disease Rat Model.
BioMed research international20196843265(2019)
Sun C,Wang Y,Mo M,Song C,Wang X,Chen S,Liu Y

Nurr1 promotes neurogenesis of dopaminergic neuron and represses inflammatory factors in the transwell coculture system of neural stem cells and microglia.
CNS neuroscience & therapeutics24(9)790-800(2018 09)
Chen XX,Qian Y,Wang XP,Tang ZW,Xu JT,Lin H,Yang ZY,Song XB,Lu D,Guo JZ,Bian LG,Li Y,Zhou L,Deng XL

Correlation between Nurr1 expression and drug resistance in the brain of rats with epilepsy.
European review for medical and pharmacological sciences22(5)1506-1513(2018 03)
Li HY,Liu F,Wang HR

Effect of Wnt1 and Wnt5a on the development of dopaminergic neurons, and toxicity induced by combined exposure to paraquat and maneb during gestation and lactation.
Molecular medicine reports16(6)9721-9728(2017 Dec)
Ma J,Huang C,Ma K,Wu YP,Li BX,Sun Y

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Nr4a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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