F8a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	F8a1
Entrez Gene ID	501661
Full Name	coagulation factor VIII-associated 1
Synonyms	F8a,Hap40,RGD1566014
General protein information	Preferred Names coagulation factor VIII-associated 1 Names factor VIII intron 22 protein coagulation factor VIII-associated (intronic transcript) 1 factor 8-associated gene A huntingtin-associated protein 40
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q31

mRNA and Protein(s)

mRNA	Protein	Name
NM_001109323.1	NP_001102793.1	40-kDa huntingtin-associated protein

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	F8A1	XP_001091814.1
Bos taurus (cattle)	LOC617475	XP_002699745.1
Rattus norvegicus (Norway rat)	F8a1	NP_001102793.1
Homo sapiens (human)	F8A2	NP_001007524.1
Homo sapiens (human)	F8A1	NP_036283.2
Mus musculus (house mouse)	F8a	NP_032004.2
Danio rerio (zebrafish)	zgc:101679	NP_001006078.1
Homo sapiens (human)	F8A3	NP_001007525.1
Xenopus tropicalis (tropical clawed frog)	f8a1	NP_001072171.1

Gene Ontology
Bibliography

Related articles in PubMed

The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity.
Huang ZN, Her LS
Molecular neurobiology54(9)7382-7400(2017 11)

Novel variant of neuronal intranuclear rodlet immunoreactive for 40 kDa huntingtin associated protein and ubiquitin in the mouse brain.
Milman P, Woulfe J
The Journal of comparative neurology521(16)3832-46(2013 Nov)

Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
Pal A, Severin F, Lommer B, Shevchenko A, Zerial M
The Journal of cell biology172(4)605-18(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following F8a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F8a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa40370	NM_001109323.1 Latest version!	Rattus norvegicus coagulation factor VIII-associated 1 (F8a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

F8a1 ( NM_001109323.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102793.1 Rattus norvegicus coagulation factor VIII-associated 1 (F8a1), mRNA.

Price & Availability↑

CloneID	ORa40370
Clone ID Related Accession (Same CDS sequence)	NM_001109323.1
Accession Version	NM_001109323.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Rattus norvegicus(Norway rat)
Product	40-kDa huntingtin-associated protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474110.1. On or before Oct 4, 2007 this sequence version replaced XM_001053469.1, XM_577058.2.

ATGGCGGCGG GCTCCGCGTC GTCCCTGGGC GGAGGCTCCT GGCCAGGCTC TGAGGCTGGG 
GACTTCTTGG CCCGCTACCG GCAGGTGTCC AACAAGCTCA AGAAGCGCTT CTTGCGGAAG 
CCGAACGTGG CGGAGGCCGG GGAGCAGTTC GCACAGCTGG CCCGGGAGCT GCGAGCTCAA 
GAGTGCCTGC CTTATGCCGC CTGGTGCCAG CTGGCTGTGG CACGCTGCCA GCAGGCGCTC 
TTCCATGGGC CCGGGGAAGC GCTGGCCCTT ACAGAGGCGG CCCGACTTTT CCTGAGGCAG 
GAGTGCGATG CGCGCCAACG CCTGGGCTGT CCTGCGGCTT ATGGGGAGCC TTTGCAGGCG 
GCCGCCAGCG CCCTTGGCGC CGCCGTGCGC CTGCACCTTG AGCTGGGCCA GCCCGCCGCT 
GCTGCCGCAC TGTGCCTAGA ACTGGCTGCC GCCCTTCGCG CTGTGGGCCA GCCAGCCGCT 
GCTGCAGGTC ACTTTCAACG TGCTGCCCAG CTGCACCTGC CCCTGATGCC ACTGGCCGCG 
CTGCAGGCAC TTGGTGATGC TGCCTCCTGC CAGTTGCTGG CGCGCGACTA CACTGGCGCC 
CTGGCGGTTT TTACACGCAT GCAACGCCTG GCACGGGAGC ATGGGGGCCA CCCGGTACAG 
CAACCCGAGC TGCCGCAGCA GCTGCCTTCT GTGCCTCAGC CATCTCTGCC GGGACCCCAG 
CCGAGACCTG TCTTGGGCTC TACCTTGCCC CTGCCGCTGC CCCCGGACCA CGCCCCAGGC 
TCTGTTGCGC AGTCACCTGG TACACTCGGT GCCTTCGCTG ACGTTCTTGT CAGGTGTGAG 
GTGTCCCGTG TATTGTTGCT GCTGCTCCTG CAACCACCGC CTGCCAAGCT GCTGCCTGAG 
CACGCCCAGA CCCTGGAGAA GTACTCTTGG GAGGCTTTCG ATGGCCATGG CCAGGATAGC 
AGCGGCCAGC TTCCAGAGGA GCTGTTTTTG TTATTGCAGT CCCTGGTCAT GGCTGCCCAC 
GAAAAGGATA CTGAAGGCAT CAAGAAGCTG CAGGTGGAGA TGTGGCCACT GCTAACTGCT 
GAGCAGAACC ACCTCCTCCA CCTCGTTCTG CAGGAAACCA TCTCTCCCTC GGGACAGGGG 
GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102793.1
CDS	51..1196
Translation	MAAGSASSLGGGSWPGSEAGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALAVFTRMQRLAREHGGHPVQQPELPQQLPSVPQPSLPGPQPRPVLGSTLPLPLPPDHAPGSVAQSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDGHGQDSSGQLPEELFLLLQSLVMAAHEKDTEGIKKLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV

Target ORF information:

RefSeq Version	NM_001109323.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coagulation factor VIII-associated 1 (F8a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109323.1

ORF Insert Sequence:

ATGGCGGCGG GCTCCGCGTC GTCCCTGGGC GGAGGCTCCT GGCCAGGCTC TGAGGCTGGG 
GACTTCTTGG CCCGCTACCG GCAGGTGTCC AACAAGCTCA AGAAGCGCTT CTTGCGGAAG 
CCGAACGTGG CGGAGGCCGG GGAGCAGTTC GCACAGCTGG CCCGGGAGCT GCGAGCTCAA 
GAGTGCCTGC CTTATGCCGC CTGGTGCCAG CTGGCTGTGG CACGCTGCCA GCAGGCGCTC 
TTCCATGGGC CCGGGGAAGC GCTGGCCCTT ACAGAGGCGG CCCGACTTTT CCTGAGGCAG 
GAGTGCGATG CGCGCCAACG CCTGGGCTGT CCTGCGGCTT ATGGGGAGCC TTTGCAGGCG 
GCCGCCAGCG CCCTTGGCGC CGCCGTGCGC CTGCACCTTG AGCTGGGCCA GCCCGCCGCT 
GCTGCCGCAC TGTGCCTAGA ACTGGCTGCC GCCCTTCGCG CTGTGGGCCA GCCAGCCGCT 
GCTGCAGGTC ACTTTCAACG TGCTGCCCAG CTGCACCTGC CCCTGATGCC ACTGGCCGCG 
CTGCAGGCAC TTGGTGATGC TGCCTCCTGC CAGTTGCTGG CGCGCGACTA CACTGGCGCC 
CTGGCGGTTT TTACACGCAT GCAACGCCTG GCACGGGAGC ATGGGGGCCA CCCGGTACAG 
CAACCCGAGC TGCCGCAGCA GCTGCCTTCT GTGCCTCAGC CATCTCTGCC GGGACCCCAG 
CCGAGACCTG TCTTGGGCTC TACCTTGCCC CTGCCGCTGC CCCCGGACCA CGCCCCAGGC 
TCTGTTGCGC AGTCACCTGG TACACTCGGT GCCTTCGCTG ACGTTCTTGT CAGGTGTGAG 
GTGTCCCGTG TATTGTTGCT GCTGCTCCTG CAACCACCGC CTGCCAAGCT GCTGCCTGAG 
CACGCCCAGA CCCTGGAGAA GTACTCTTGG GAGGCTTTCG ATGGCCATGG CCAGGATAGC 
AGCGGCCAGC TTCCAGAGGA GCTGTTTTTG TTATTGCAGT CCCTGGTCAT GGCTGCCCAC 
GAAAAGGATA CTGAAGGCAT CAAGAAGCTG CAGGTGGAGA TGTGGCCACT GCTAACTGCT 
GAGCAGAACC ACCTCCTCCA CCTCGTTCTG CAGGAAACCA TCTCTCCCTC GGGACAGGGG 
GTCTGA