Nanos2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nanos2
Entrez Gene ID	365213
Full Name	nanos C2HC-type zinc finger 2
Synonyms	RGD1562436
General protein information	Preferred Names nanos C2HC-type zinc finger 2 Names nanos homolog 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108908.1	NP_001102378.1	nanos homolog 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	NANOS2	NP_001025032.1
Macaca mulatta (Rhesus monkey)	NANOS2	XP_001111556.1
Canis lupus familiaris (dog)	NANOS2	XP_541547.1
Bos taurus (cattle)	NANOS2	XP_002695145.1
Mus musculus (house mouse)	Nanos2	NP_918953.2
Pan troglodytes (chimpanzee)	NANOS2	XP_001167172.1
Rattus norvegicus (Norway rat)	Nanos2	NP_001102378.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression and intracellular localization of Nanos2-homologue protein in primordial germ cells and spermatogonial stem cells.
Pandey V, Tripathi A, Dubey PK
Zygote (Cambridge, England)27(2)82-88(2019 Apr)

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.
Bhandari D, Raisch T, Weichenrieder O, Jonas S, Izaurralde E
Genes & development28(8)888-901(2014 Apr)

Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry.
Jørgensen A, Nielsen JE, Blomberg Jensen M, Græm N, Rajpert-De Meyts E
Molecular human reproduction18(11)523-34(2012 Nov)

Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male.
Geyer CB, Saba R, Kato Y, Anderson AJ, Chappell VK, Saga Y, Eddy EM
Biology of reproduction86(4)127(2012 Apr)

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.
Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y
Proceedings of the National Academy of Sciences of the United States of America107(8)3594-9(2010 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nanos2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nanos2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41610	NM_001108908.1 Latest version!	Rattus norvegicus nanos C2HC-type zinc finger 2 (Nanos2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nanos2 ( NM_001108908.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102378.1 Rattus norvegicus nanos C2HC-type zinc finger 2 (Nanos2), mRNA.

Price & Availability↑

CloneID	ORa41610
Clone ID Related Accession (Same CDS sequence)	NM_001108908.1
Accession Version	NM_001108908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568476800000
Organism	Rattus norvegicus(Norway rat)
Product	nanos homolog 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_344868.3, XM_001075271.1.

ATGGACCTGC CACCCTTTGA CAGGTGGAGA GACTACTTTA ACCTGAGCCA GGTGGTGCTG 
GGTATAATTC AGAGCCGGAA GCAAAGACTG GAGGATGAGG TGTCTGAGGA ACTGGCCTCC 
AGGCCCCAAG GGATGAGTGA GCGGGGCCTG GAGGTCTCCC CCGGAAGTCT GGCTACTGCA 
TGCAACTTTT GCAAGCACAA CGGAGAGTCT CGTCACGTCT ACACCTCACA CCAGCTGAAG 
ACGCCTGAAG GGGTGGTAGT GTGTCCCATC CTGAGGCATT ACGTATGTCC TCTCTGTGGG 
GCCACTGGCG ACCAGGCGCA TACACTCAAG TATTGCCCAC TCAACAGCAG CCAGCAGTCT 
CTCTACCGTC GCAGTGGACG AAACTCAGCT GGTCGCAGAG TCAAGCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102378.1
CDS	80..490
Translation	MDLPPFDRWRDYFNLSQVVLGIIQSRKQRLEDEVSEELASRPQGMSERGLEVSPGSLATACNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCPLNSSQQSLYRRSGRNSAGRRVKR

Target ORF information:

RefSeq Version	NM_001108908.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nanos C2HC-type zinc finger 2 (Nanos2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108908.1

ORF Insert Sequence:

ATGGACCTGC CACCCTTTGA CAGGTGGAGA GACTACTTTA ACCTGAGCCA GGTGGTGCTG 
GGTATAATTC AGAGCCGGAA GCAAAGACTG GAGGATGAGG TGTCTGAGGA ACTGGCCTCC 
AGGCCCCAAG GGATGAGTGA GCGGGGCCTG GAGGTCTCCC CCGGAAGTCT GGCTACTGCA 
TGCAACTTTT GCAAGCACAA CGGAGAGTCT CGTCACGTCT ACACCTCACA CCAGCTGAAG 
ACGCCTGAAG GGGTGGTAGT GTGTCCCATC CTGAGGCATT ACGTATGTCC TCTCTGTGGG 
GCCACTGGCG ACCAGGCGCA TACACTCAAG TATTGCCCAC TCAACAGCAG CCAGCAGTCT 
CTCTACCGTC GCAGTGGACG AAACTCAGCT GGTCGCAGAG TCAAGCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression and intracellular localization of Nanos2-homologue protein in primordial germ cells and spermatogonial stem cells.
Zygote (Cambridge, England)27(2)82-88(2019 Apr)
Pandey V,Tripathi A,Dubey PK

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.
Genes & development28(8)888-901(2014 Apr)
Bhandari D,Raisch T,Weichenrieder O,Jonas S,Izaurralde E

Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry.
Molecular human reproduction18(11)523-34(2012 Nov)
Jørgensen A,Nielsen JE,Blomberg Jensen M,Græm N,Rajpert-De Meyts E

Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male.
Biology of reproduction86(4)127(2012 Apr)
Geyer CB,Saba R,Kato Y,Anderson AJ,Chappell VK,Saga Y,Eddy EM

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.
Proceedings of the National Academy of Sciences of the United States of America107(8)3594-9(2010 Feb)
Suzuki A,Igarashi K,Aisaki K,Kanno J,Saga Y