| Gene Symbol | Pycr2 |
| Entrez Gene ID | 364064 |
| Full Name | pyrroline-5-carboxylate reductase 2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Pycr2 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Pycr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pycr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa02704 Clone ID Related Accession (Same CDS sequence) NM_001012208.1 Accession Version NM_001012208.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550246400000 Organism Rattus norvegicus(Norway rat) Product pyrroline-5-carboxylate reductase 2 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079222.1. On Feb 11, 2005 this sequence version replaced XM_344180.1. ##Evidence-Data-START## Transcript exon combination :: BC079222.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961ATGAGCGTGG GTTTCATCGG CGCGGGCCAG CTGGCCTGTG CTCTGGCGCG GGGCTTCACG
GCCGCGGGCG TCCTGTCGGC TCACAAGATA ATAGCCAGCT CCCCGGAAAT GGACCTGCCC
ACGGTGTCTG CGCTCAGGAA GATGGGTGTG AATCTGACCC GAAGCAATAA GGACACGGTG
CGGCACAGTG ACGTCCTGTT CCTGGCTGTG AAGCCCCACA TCATCCCCTT CATCCTGGAT
GAGATCGGGG CTGACGTGCA GGAGAGGCAC ATCGTGGTCT CCTGTGCGGC TGGCGTCACC
ATCAGTTCTG TGGAGAAGAA GCTGATGGCT TTCCAGCCAG CCCCCAAAGT GATCCGCTGC
ATGACCAACA CGCCTGTGGT GGTCCGAGAG GGGGCCACTG TGTACGCCAC AGGCACCCAT
GCTCTGGTGG AAGATGGGAA GCTTCTGGAG CAGCTGATGA GCAGTGTGGG CTTCTGCACA
GAGGTGGAGG AAGACCTCAT TGATGCTATC ACAGGGCTCA GCGGCAGCGG GCCCGCCTAC
GCGTTTATGG CCCTGGATGC GCTGGCAGAC GGCGGGGTGA AGATGGGCGT GCCGCGGCGC
CTGGCAGTCC GACTGGGAGC TCAGGCGTTG CTGGGAGCAG CTAAGATGCT GCTGGATTCA
GAGGACCACC CGGGCCAGCT CAAGGACAAC GTCTGCTCCC CTGGGGGGGC CACCATCCAT
GCCCTGCACT TCCTGGAGAG TGGGGGCTTC CGCTCTCTGC TCATCAATGC AGTTGAGGCC
TCCTGTATTC GAACAAGAGA GCTGCAGTCC ATGGCTGACC AAGAAAAGGT GTCCCCTGCC
GCCCTTAAGA AGACCCTCCT GGACAGAGTG AAGCTGGAGT CACCCACGGT GTCCACGCTG
GCCCCACCCA GCTCAGGGAA ACTCCTTACA AGAAACCCTG CCCAGGGAAG CAAGAGGGAG
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001012208.1 CDS 116..1078 Translation 
Target ORF information:
RefSeq Version NM_001012208.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus pyrroline-5-carboxylate reductase 2 (Pycr2), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001012208.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961ATGAGCGTGG GTTTCATCGG CGCGGGCCAG CTGGCCTGTG CTCTGGCGCG GGGCTTCACG
GCCGCGGGCG TCCTGTCGGC TCACAAGATA ATAGCCAGCT CCCCGGAAAT GGACCTGCCC
ACGGTGTCTG CGCTCAGGAA GATGGGTGTG AATCTGACCC GAAGCAATAA GGACACGGTG
CGGCACAGTG ACGTCCTGTT CCTGGCTGTG AAGCCCCACA TCATCCCCTT CATCCTGGAT
GAGATCGGGG CTGACGTGCA GGAGAGGCAC ATCGTGGTCT CCTGTGCGGC TGGCGTCACC
ATCAGTTCTG TGGAGAAGAA GCTGATGGCT TTCCAGCCAG CCCCCAAAGT GATCCGCTGC
ATGACCAACA CGCCTGTGGT GGTCCGAGAG GGGGCCACTG TGTACGCCAC AGGCACCCAT
GCTCTGGTGG AAGATGGGAA GCTTCTGGAG CAGCTGATGA GCAGTGTGGG CTTCTGCACA
GAGGTGGAGG AAGACCTCAT TGATGCTATC ACAGGGCTCA GCGGCAGCGG GCCCGCCTAC
GCGTTTATGG CCCTGGATGC GCTGGCAGAC GGCGGGGTGA AGATGGGCGT GCCGCGGCGC
CTGGCAGTCC GACTGGGAGC TCAGGCGTTG CTGGGAGCAG CTAAGATGCT GCTGGATTCA
GAGGACCACC CGGGCCAGCT CAAGGACAAC GTCTGCTCCC CTGGGGGGGC CACCATCCAT
GCCCTGCACT TCCTGGAGAG TGGGGGCTTC CGCTCTCTGC TCATCAATGC AGTTGAGGCC
TCCTGTATTC GAACAAGAGA GCTGCAGTCC ATGGCTGACC AAGAAAAGGT GTCCCCTGCC
GCCCTTAAGA AGACCCTCCT GGACAGAGTG AAGCTGGAGT CACCCACGGT GTCCACGCTG
GCCCCACCCA GCTCAGGGAA ACTCCTTACA AGAAACCCTG CCCAGGGAAG CAAGAGGGAG
TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination.
American journal of human genetics96(5)709-19(2015 May)
Nakayama T,Al-Maawali A,El-Quessny M,Rajab A,Khalil S,Stoler JM,Tan WH,Nasir R,Schmitz-Abe K,Hill RS,Partlow JN,Al-Saffar M,Servattalab S,LaCoursiere CM,Tambunan DE,Coulter ME,Elhosary PC,Gorski G,Barkovich AJ,Markianos K,Poduri A,Mochida GH
Functional specialization in proline biosynthesis of melanoma.
PloS one7(9)e45190(2012)
De Ingeniis J,Ratnikov B,Richardson AD,Scott DA,Aza-Blanc P,De SK,Kazanov M,Pellecchia M,Ronai Z,Osterman AL,Smith JW
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