Ror1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ror1
Entrez Gene ID	362550
Full Name	receptor tyrosine kinase-like orphan receptor 1
Synonyms	RGD1559469
General protein information	Preferred Names receptor tyrosine kinase-like orphan receptor 1 Names inactive tyrosine-protein kinase transmembrane receptor ROR1 neurotrophic tyrosine kinase, receptor-related 1 tyrosine-protein kinase transmembrane receptor ROR1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q33

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108671.1	NP_001102141.1	inactive tyrosine-protein kinase transmembrane receptor ROR1 precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	ror1	XP_005165942.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006219	XP_316289.4
Homo sapiens (human)	ROR1	NP_005003.2
Pan troglodytes (chimpanzee)	ROR1	XP_513458.2
Mus musculus (house mouse)	Ror1	NP_038873.2
Drosophila melanogaster (fruit fly)	Ror	NP_476962.1
Xenopus tropicalis (tropical clawed frog)	ror1	XP_002931659.2
Bos taurus (cattle)	ROR1	XP_002686397.2
Gallus gallus (chicken)	ROR1	NP_989840.1
Canis lupus familiaris (dog)	ROR1	XP_005620390.1
Rattus norvegicus (Norway rat)	Ror1	NP_001102141.1

Gene Ontology
Bibliography

Related articles in PubMed

Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target.
Heliste J, Jokilammi A, Paatero I, Chakroborty D, Stark C, Savunen T, Laaksonen M, Elenius K
BMC cardiovascular disorders18(1)196(2018 10)

ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice.
Diaz-Horta O, Abad C, Sennaroglu L, Foster J 2nd, DeSmidt A, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Grati M, Fitoz S, Liu XZ, Farooq A, Imtiaz F, Currall BB, Morton CC, Nishita M, Minami Y, Lu Z, Walz K, Tekin M
Proceedings of the National Academy of Sciences of the United States of America113(21)5993-8(2016 May)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a.
Fukuda T, Chen L, Endo T, Tang L, Lu D, Castro JE, Widhopf GF 2nd, Rassenti LZ, Cantwell MJ, Prussak CE, Carson DA, Kipps TJ
Proceedings of the National Academy of Sciences of the United States of America105(8)3047-52(2008 Feb)

Identification and characterization of rat Ror1 and Ror2 genes in silico.
Katoh M, Katoh M
International journal of molecular medicine15(3)533-8(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ror1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ror1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08086	NM_001108671.1 Latest version!	Rattus norvegicus receptor tyrosine kinase-like orphan receptor 1 (Ror1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ror1 ( NM_001108671.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102141.1 Rattus norvegicus receptor tyrosine kinase-like orphan receptor 1 (Ror1), mRNA.

Price & Availability↑

CloneID	ORa08086
Clone ID Related Accession (Same CDS sequence)	NM_001108671.1
Accession Version	NM_001108671.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2814bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559491200000
Organism	Rattus norvegicus(Norway rat)
Product	inactive tyrosine-protein kinase transmembrane receptor ROR1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473998.1. On or before Oct 4, 2007 this sequence version replaced XM_216445.4, XM_001056577.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCACCGGC CGCGCCGCCG CGGGACGCGC CCGCCACCGC TGGCGCTGCT GGCCGCGCTG 
CTGCTGGCCG CACGCGGGGC TGCTGCCCAA GAAACAGAGT TGTCAGTCAG TGCTGAGCTG 
GTGCCTACCT CATCCTGGAA CACTTCAAGT GAAATTGACA AAGATTCTTA CTTAACCCTT 
GATGAACCTA TGAATAACAT CACAACATCC CTGGGCCAGA CTGCAGAACT GCACTGCAAA 
GTGTCTGGGA ATCCACCTCC CAATATCCGC TGGTTCAAGA ATGACGCACC TGTGGTTCAA 
GAACCGCGTA GAATCTCCTT CCGGGCCACC AACTATGGCT CTCGGCTGCG GATCAGAAAC 
CTCGACACCA CAGACACTGG TTACTTCCAG TGTGTGGCAA CAAGTGGCAA GAAAGTGGTT 
TCTACCACTG GAGTCCTGTT TGTCAAGTTT GGACCTCCTC CAACTGCAAG CCCAGGATCC 
TCAGACGAGT ATGAAGAAGA TGGATTCTGT CAGCCATACC GAGGCATTGC ATGTGCACGA 
TTTATTGGCA ACCGCACTGT GTATATGGAG TCTTTGCATA TGCAGGGGGA AATAGAAAAT 
CAGATCACAG CTGCCTTCAC CATGATTGGC ACCTCCAGCC ATTTATCTGA TAAGTGCTCT 
CAGTTCGCCA TCCCTTCCCT GTGCCACTAC GCCTTCCCAT ACTGTGACGA AACCTCATCT 
GTCCCAAAGC CCCGAGACCT GTGTCGGGAT GAATGTGAAG TGCTAGAAAA TGTCCTGTGT 
CACACAGAGT ACATTTTTGC CAGATCGAAT CCCATGATTC TGATGAGGCT GAAGTTGCCA 
AACTGTGAGG ATCTCCCTCA GCCGGAGAGC CCAGAAGCTG CAAACTGCAT TCGGATTGGC 
ATCCCCATGG CGGATCCTAT AAACAAAAAT CACAAATGCT ACAACAGCAC AGGTGTAGAC 
TACCGGGGAA CTGTCAGTGT GACCAAGTCA GGACGCCAGT GCCAACCTTG GAATTCTCAG 
TACCCACACA CACACAGCTT CACTGCCCTG CGCTTTCCGG AGCTCAACGG AGGCCACTCC 
TACTGCCGCA ACCCTGGCAA CCAGAAGGAA GCTCCCTGGT GCTTTACCTT GGATGAAAAC 
TTTAAGTCTG ACCTGTGCGA CATCCCGGCA TGTGATTCCA AAGATTCCAA AGAGAAGAAT 
AAAATGGAAA TCCTGTATAT TCTGGTGCCA AGTGTGGCCA TTCCCCTGGC TATTGCCTTC 
CTCTTCTTCT TCATCTGTGT GTGCCGAAAT AACCAGAAGT CCCCGTCACC ACCCGTCCAG 
AGGCAGCCAA AACCTGTCAG AGGACAGAAC GTAGAGATGT CCATGCTGAA TGCATACAAG 
CCCAAGAGCA AAGCTAAGGA GCTGCCTCTT TCTGCTGTGC GTTTCATGGA AGAATTGGGT 
GAATGTACCT TTGGAAAAAT CTATAAGGGC CATCTCTACC TCCCAGGCAT GGACCATGCA 
CAGCTGGTGG CTATCAAAAC CTTGAAAGAC TATAACAACC CCCAGCAGTG GACAGAATTT 
CAACAGGAAG CCTCTCTCAT GGCCGAACTA CACCACCCTA ATATTGTATG TCTCCTTGGT 
GCCGTCACCC AGGAACAACC TGTGTGTATG CTCTTTGAGT ATATGAACCA GGGAGATCTC 
CATGAGTTCC TCATCATGCG ATCCCCACAT TCCGATGTTG GCTGCAGCAG TGATGAGGAC 
GGAACGGTCA AATCCAGCCT GGACCACGGA GATTTCTTAC ACATCGCAAT TCAGATCGCG 
GCTGGCATGG AGTACCTCTC TAGTCACTTC TTCGTGCACA AGGACCTTGC AGCTCGCAAC 
ATTTTAATTG GAGAACAACT GCATGTGAAG ATTTCAGACC TTGGGCTTTC CAGAGAAATT 
TACTCTGCCG ATTACTATAG GGTGCAGAGT AAGTCTTCAC TGCCCATCCG CTGGATGCCC 
CCTGAGGCGA TCATGTACGG CAAATTCTCC TCAGATTCTG ATATCTGGTC TTTTGGGGTT 
GTGTTGTGGG AGATTTTCAG CTTTGGACTC CAGCCATATT ATGGGTTTAG TAATCAGGAA 
GTGATTGAAA TGGTGCGGAA GCGACAGCTC TTACCGTGTT CTGAAGACTG CCCGCCGCGA 
ATGTACAGCC TCATGACCGA GTGCTGGAAT GAGATTCCTT CCAGGAGACC ACGCTTTAAG 
GACATCCACG TCCGGCTTCG ATCCTGGGAG GGCCTCTCAA GTCACACCAG CTCAACCACT 
CCCTCGGGTG GAAATGCTAC CACGCAGACC ACCTCCCTCA GCGCCAGCCC TGTGAGTAAC 
CTCAGCAACC CCCGATTTCC CAATTACATG TTCCCGAGCC AGGGGATCCC ACCACAGGGT 
CAAATCGCTG GTTTCATTGG CCCAGCGATA CCGCAGAACC AGCGCTTCAT CCCCATTAAC 
GGATATCCAA TACCTCCCGG ATACGCAGCC TTTCCTGCTG CCCACTACCA GCCTGCGGGA 
CCTCCCAGGG TGATTCAGCA CTGCCCGCCT CCAAAGAGCC GGTCCCCAAG CAGCGCCAGT 
GGATCGACCA GCACTGGCCA TGTGGCCAGC TTGCCCTCAT CAGGATCCAA TCAGGAAGCA 
AACGTTCCTT TGCTACCCCA CATGTCAATC CCAAATCACC CCGGTGGAAT GGGGATCACT 
GTTTTCGGCA ACAAATCTCA AAAACCCTAC AAAATAGACT CAAAACAACC ATCTTTGCTT 
GGGGACTCCA ATATCCATGG GCACACCGAG TCTATGATTT CTGCGGAAGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102141.1
CDS	426..3239
Translation	MHRPRRRGTRPPPLALLAALLLAARGAAAQETELSVSAELVPTSSWNTSSEIDKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPNIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATSGKKVVSTTGVLFVKFGPPPTASPGSSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCHTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIAFLFFFICVCRNNQKSPSPPVQRQPKPVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRFPNYMFPSQGIPPQGQIAGFIGPAIPQNQRFIPINGYPIPPGYAAFPAAHYQPAGPPRVIQHCPPPKSRSPSSASGSTSTGHVASLPSSGSNQEANVPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQPSLLGDSNIHGHTESMISAEV

Target ORF information:

RefSeq Version	NM_001108671.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor tyrosine kinase-like orphan receptor 1 (Ror1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108671.1

ORF Insert Sequence:

ATGCACCGGC CGCGCCGCCG CGGGACGCGC CCGCCACCGC TGGCGCTGCT GGCCGCGCTG 
CTGCTGGCCG CACGCGGGGC TGCTGCCCAA GAAACAGAGT TGTCAGTCAG TGCTGAGCTG 
GTGCCTACCT CATCCTGGAA CACTTCAAGT GAAATTGACA AAGATTCTTA CTTAACCCTT 
GATGAACCTA TGAATAACAT CACAACATCC CTGGGCCAGA CTGCAGAACT GCACTGCAAA 
GTGTCTGGGA ATCCACCTCC CAATATCCGC TGGTTCAAGA ATGACGCACC TGTGGTTCAA 
GAACCGCGTA GAATCTCCTT CCGGGCCACC AACTATGGCT CTCGGCTGCG GATCAGAAAC 
CTCGACACCA CAGACACTGG TTACTTCCAG TGTGTGGCAA CAAGTGGCAA GAAAGTGGTT 
TCTACCACTG GAGTCCTGTT TGTCAAGTTT GGACCTCCTC CAACTGCAAG CCCAGGATCC 
TCAGACGAGT ATGAAGAAGA TGGATTCTGT CAGCCATACC GAGGCATTGC ATGTGCACGA 
TTTATTGGCA ACCGCACTGT GTATATGGAG TCTTTGCATA TGCAGGGGGA AATAGAAAAT 
CAGATCACAG CTGCCTTCAC CATGATTGGC ACCTCCAGCC ATTTATCTGA TAAGTGCTCT 
CAGTTCGCCA TCCCTTCCCT GTGCCACTAC GCCTTCCCAT ACTGTGACGA AACCTCATCT 
GTCCCAAAGC CCCGAGACCT GTGTCGGGAT GAATGTGAAG TGCTAGAAAA TGTCCTGTGT 
CACACAGAGT ACATTTTTGC CAGATCGAAT CCCATGATTC TGATGAGGCT GAAGTTGCCA 
AACTGTGAGG ATCTCCCTCA GCCGGAGAGC CCAGAAGCTG CAAACTGCAT TCGGATTGGC 
ATCCCCATGG CGGATCCTAT AAACAAAAAT CACAAATGCT ACAACAGCAC AGGTGTAGAC 
TACCGGGGAA CTGTCAGTGT GACCAAGTCA GGACGCCAGT GCCAACCTTG GAATTCTCAG 
TACCCACACA CACACAGCTT CACTGCCCTG CGCTTTCCGG AGCTCAACGG AGGCCACTCC 
TACTGCCGCA ACCCTGGCAA CCAGAAGGAA GCTCCCTGGT GCTTTACCTT GGATGAAAAC 
TTTAAGTCTG ACCTGTGCGA CATCCCGGCA TGTGATTCCA AAGATTCCAA AGAGAAGAAT 
AAAATGGAAA TCCTGTATAT TCTGGTGCCA AGTGTGGCCA TTCCCCTGGC TATTGCCTTC 
CTCTTCTTCT TCATCTGTGT GTGCCGAAAT AACCAGAAGT CCCCGTCACC ACCCGTCCAG 
AGGCAGCCAA AACCTGTCAG AGGACAGAAC GTAGAGATGT CCATGCTGAA TGCATACAAG 
CCCAAGAGCA AAGCTAAGGA GCTGCCTCTT TCTGCTGTGC GTTTCATGGA AGAATTGGGT 
GAATGTACCT TTGGAAAAAT CTATAAGGGC CATCTCTACC TCCCAGGCAT GGACCATGCA 
CAGCTGGTGG CTATCAAAAC CTTGAAAGAC TATAACAACC CCCAGCAGTG GACAGAATTT 
CAACAGGAAG CCTCTCTCAT GGCCGAACTA CACCACCCTA ATATTGTATG TCTCCTTGGT 
GCCGTCACCC AGGAACAACC TGTGTGTATG CTCTTTGAGT ATATGAACCA GGGAGATCTC 
CATGAGTTCC TCATCATGCG ATCCCCACAT TCCGATGTTG GCTGCAGCAG TGATGAGGAC 
GGAACGGTCA AATCCAGCCT GGACCACGGA GATTTCTTAC ACATCGCAAT TCAGATCGCG 
GCTGGCATGG AGTACCTCTC TAGTCACTTC TTCGTGCACA AGGACCTTGC AGCTCGCAAC 
ATTTTAATTG GAGAACAACT GCATGTGAAG ATTTCAGACC TTGGGCTTTC CAGAGAAATT 
TACTCTGCCG ATTACTATAG GGTGCAGAGT AAGTCTTCAC TGCCCATCCG CTGGATGCCC 
CCTGAGGCGA TCATGTACGG CAAATTCTCC TCAGATTCTG ATATCTGGTC TTTTGGGGTT 
GTGTTGTGGG AGATTTTCAG CTTTGGACTC CAGCCATATT ATGGGTTTAG TAATCAGGAA 
GTGATTGAAA TGGTGCGGAA GCGACAGCTC TTACCGTGTT CTGAAGACTG CCCGCCGCGA 
ATGTACAGCC TCATGACCGA GTGCTGGAAT GAGATTCCTT CCAGGAGACC ACGCTTTAAG 
GACATCCACG TCCGGCTTCG ATCCTGGGAG GGCCTCTCAA GTCACACCAG CTCAACCACT 
CCCTCGGGTG GAAATGCTAC CACGCAGACC ACCTCCCTCA GCGCCAGCCC TGTGAGTAAC 
CTCAGCAACC CCCGATTTCC CAATTACATG TTCCCGAGCC AGGGGATCCC ACCACAGGGT 
CAAATCGCTG GTTTCATTGG CCCAGCGATA CCGCAGAACC AGCGCTTCAT CCCCATTAAC 
GGATATCCAA TACCTCCCGG ATACGCAGCC TTTCCTGCTG CCCACTACCA GCCTGCGGGA 
CCTCCCAGGG TGATTCAGCA CTGCCCGCCT CCAAAGAGCC GGTCCCCAAG CAGCGCCAGT 
GGATCGACCA GCACTGGCCA TGTGGCCAGC TTGCCCTCAT CAGGATCCAA TCAGGAAGCA 
AACGTTCCTT TGCTACCCCA CATGTCAATC CCAAATCACC CCGGTGGAAT GGGGATCACT 
GTTTTCGGCA ACAAATCTCA AAAACCCTAC AAAATAGACT CAAAACAACC ATCTTTGCTT 
GGGGACTCCA ATATCCATGG GCACACCGAG TCTATGATTT CTGCGGAAGT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target.
BMC cardiovascular disorders18(1)196(2018 10)
Heliste J,Jokilammi A,Paatero I,Chakroborty D,Stark C,Savunen T,Laaksonen M,Elenius K

ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice.
Proceedings of the National Academy of Sciences of the United States of America113(21)5993-8(2016 May)
Diaz-Horta O,Abad C,Sennaroglu L,Foster J 2nd,DeSmidt A,Bademci G,Tokgoz-Yilmaz S,Duman D,Cengiz FB,Grati M,Fitoz S,Liu XZ,Farooq A,Imtiaz F,Currall BB,Morton CC,Nishita M,Minami Y,Lu Z,Walz K,Tekin M

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a.
Proceedings of the National Academy of Sciences of the United States of America105(8)3047-52(2008 Feb)
Fukuda T,Chen L,Endo T,Tang L,Lu D,Castro JE,Widhopf GF 2nd,Rassenti LZ,Cantwell MJ,Prussak CE,Carson DA,Kipps TJ

Identification and characterization of rat Ror1 and Ror2 genes in silico.
International journal of molecular medicine15(3)533-8(2005 Mar)
Katoh M,Katoh M

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Ror1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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