| Gene Symbol | Alkbh3 |
| Entrez Gene ID | 362169 |
| Full Name | alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Alkbh3 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Alkbh3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Alkbh3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa05317 Clone ID Related Accession (Same CDS sequence) XM_006234585.3 , NM_001014180.1 Accession Version NM_001014180.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 888bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550246400000 Organism Rattus norvegicus(Norway rat) Product alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083756.1. On Apr 20, 2005 this sequence version replaced XM_342469.2. ##Evidence-Data-START## Transcript exon combination :: BC083756.1, FQ229710.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGGGGACA AGAGACAGCG AGCCCGAGTG CAGGGAGCCT GGGCCACACC TACCAAGAGC
CAGTCTGCTG CTCGGCCAGC TACTCCTGCT AGAAGCCGTC CTTCCCAGAC ACCAGGGCCA
AGCTGGAGGA GCAAGGAACA GCAGCAATGT GACCGACGGT TTGTGTTCAA AGAACCGCAG
CTGGTTGTAC GTGCAGCCCC AGAGCCCAGA GTGATTGACA GGGAGGGTGT GTACGAAATC
AGCCTGTCCC CTACAGGTGT GTCTAGGGTG TGTTTATATC CTGGCTTTGT GGACTTGAAG
GAAGCTGACT GGATCTTGGA GCGGCTTTGT CAAGATGTCC CCTGGAAACA GAGGATGGGC
ATCAGAGAGG ATATAACTTA TCCGCAACCA AGACTTACAG CATGGTATGG AGAGCTTCCT
TACACTTACT CAAGAGTCAC TATGGAACCA AATCCTCACT GGCTTCCTGT GCTGTGGACT
CTGAAGAGCC GCATTGAGGA GAACACTGGC CACACCTTCA ACTCCTTGCT GTGTAATTTT
TACCGGGACG AGAAGGACAG TGTGGACTGG CACAGCGATG ATGAGCCATC CCTGGGGAGC
TGCCCTGTCA TTGCTTCACT CAGTTTTGGT GCCACTCGGA CTTTTGAGAT GAGGAAGAAA
CCCCCACCTG AAGAGAATGG AGACTATACT TATGTGGAGA GAGTGAAGAT ACCATTGGAT
CACGGGACCT TGCTAATCAT GGAAGGAGCC ACGCAAGCTG ACTGGCAGCA CCGAGTGCCC
AAGGAATACC ACTCCAGAGA ACGGAGAGTA AACCTAACCT TTCGGACCGT TTATCCAGAC
CCAAGAGGAG CCCCCGGTGA TACTTCTGCA GAGCTGCCAC TGAGGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001014202.1 CDS 132..1019 Translation 
Target ORF information:
RefSeq Version NM_001014180.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase (Alkbh3), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001014180.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGGGGACA AGAGACAGCG AGCCCGAGTG CAGGGAGCCT GGGCCACACC TACCAAGAGC
CAGTCTGCTG CTCGGCCAGC TACTCCTGCT AGAAGCCGTC CTTCCCAGAC ACCAGGGCCA
AGCTGGAGGA GCAAGGAACA GCAGCAATGT GACCGACGGT TTGTGTTCAA AGAACCGCAG
CTGGTTGTAC GTGCAGCCCC AGAGCCCAGA GTGATTGACA GGGAGGGTGT GTACGAAATC
AGCCTGTCCC CTACAGGTGT GTCTAGGGTG TGTTTATATC CTGGCTTTGT GGACTTGAAG
GAAGCTGACT GGATCTTGGA GCGGCTTTGT CAAGATGTCC CCTGGAAACA GAGGATGGGC
ATCAGAGAGG ATATAACTTA TCCGCAACCA AGACTTACAG CATGGTATGG AGAGCTTCCT
TACACTTACT CAAGAGTCAC TATGGAACCA AATCCTCACT GGCTTCCTGT GCTGTGGACT
CTGAAGAGCC GCATTGAGGA GAACACTGGC CACACCTTCA ACTCCTTGCT GTGTAATTTT
TACCGGGACG AGAAGGACAG TGTGGACTGG CACAGCGATG ATGAGCCATC CCTGGGGAGC
TGCCCTGTCA TTGCTTCACT CAGTTTTGGT GCCACTCGGA CTTTTGAGAT GAGGAAGAAA
CCCCCACCTG AAGAGAATGG AGACTATACT TATGTGGAGA GAGTGAAGAT ACCATTGGAT
CACGGGACCT TGCTAATCAT GGAAGGAGCC ACGCAAGCTG ACTGGCAGCA CCGAGTGCCC
AAGGAATACC ACTCCAGAGA ACGGAGAGTA AACCTAACCT TTCGGACCGT TTATCCAGAC
CCAAGAGGAG CCCCCGGTGA TACTTCTGCA GAGCTGCCAC TGAGGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa05317 Clone ID Related Accession (Same CDS sequence) XM_006234585.3 , NM_001014180.1 Accession Version XM_006234585.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 888bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234585.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGGGGACA AGAGACAGCG AGCCCGAGTG CAGGGAGCCT GGGCCACACC TACCAAGAGC
CAGTCTGCTG CTCGGCCAGC TACTCCTGCT AGAAGCCGTC CTTCCCAGAC ACCAGGGCCA
AGCTGGAGGA GCAAGGAACA GCAGCAATGT GACCGACGGT TTGTGTTCAA AGAACCGCAG
CTGGTTGTAC GTGCAGCCCC AGAGCCCAGA GTGATTGACA GGGAGGGTGT GTACGAAATC
AGCCTGTCCC CTACAGGTGT GTCTAGGGTG TGTTTATATC CTGGCTTTGT GGACTTGAAG
GAAGCTGACT GGATCTTGGA GCGGCTTTGT CAAGATGTCC CCTGGAAACA GAGGATGGGC
ATCAGAGAGG ATATAACTTA TCCGCAACCA AGACTTACAG CATGGTATGG AGAGCTTCCT
TACACTTACT CAAGAGTCAC TATGGAACCA AATCCTCACT GGCTTCCTGT GCTGTGGACT
CTGAAGAGCC GCATTGAGGA GAACACTGGC CACACCTTCA ACTCCTTGCT GTGTAATTTT
TACCGGGACG AGAAGGACAG TGTGGACTGG CACAGCGATG ATGAGCCATC CCTGGGGAGC
TGCCCTGTCA TTGCTTCACT CAGTTTTGGT GCCACTCGGA CTTTTGAGAT GAGGAAGAAA
CCCCCACCTG AAGAGAATGG AGACTATACT TATGTGGAGA GAGTGAAGAT ACCATTGGAT
CACGGGACCT TGCTAATCAT GGAAGGAGCC ACGCAAGCTG ACTGGCAGCA CCGAGTGCCC
AAGGAATACC ACTCCAGAGA ACGGAGAGTA AACCTAACCT TTCGGACCGT TTATCCAGAC
CCAAGAGGAG CCCCCGGTGA TACTTCTGCA GAGCTGCCAC TGAGGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006234647.1 CDS 1021..1908 Translation
Target ORF information:
RefSeq Version XM_006234585.3 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase (Alkbh3), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006234585.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGGGGACA AGAGACAGCG AGCCCGAGTG CAGGGAGCCT GGGCCACACC TACCAAGAGC
CAGTCTGCTG CTCGGCCAGC TACTCCTGCT AGAAGCCGTC CTTCCCAGAC ACCAGGGCCA
AGCTGGAGGA GCAAGGAACA GCAGCAATGT GACCGACGGT TTGTGTTCAA AGAACCGCAG
CTGGTTGTAC GTGCAGCCCC AGAGCCCAGA GTGATTGACA GGGAGGGTGT GTACGAAATC
AGCCTGTCCC CTACAGGTGT GTCTAGGGTG TGTTTATATC CTGGCTTTGT GGACTTGAAG
GAAGCTGACT GGATCTTGGA GCGGCTTTGT CAAGATGTCC CCTGGAAACA GAGGATGGGC
ATCAGAGAGG ATATAACTTA TCCGCAACCA AGACTTACAG CATGGTATGG AGAGCTTCCT
TACACTTACT CAAGAGTCAC TATGGAACCA AATCCTCACT GGCTTCCTGT GCTGTGGACT
CTGAAGAGCC GCATTGAGGA GAACACTGGC CACACCTTCA ACTCCTTGCT GTGTAATTTT
TACCGGGACG AGAAGGACAG TGTGGACTGG CACAGCGATG ATGAGCCATC CCTGGGGAGC
TGCCCTGTCA TTGCTTCACT CAGTTTTGGT GCCACTCGGA CTTTTGAGAT GAGGAAGAAA
CCCCCACCTG AAGAGAATGG AGACTATACT TATGTGGAGA GAGTGAAGAT ACCATTGGAT
CACGGGACCT TGCTAATCAT GGAAGGAGCC ACGCAAGCTG ACTGGCAGCA CCGAGTGCCC
AAGGAATACC ACTCCAGAGA ACGGAGAGTA AACCTAACCT TTCGGACCGT TTATCCAGAC
CCAAGAGGAG CCCCCGGTGA TACTTCTGCA GAGCTGCCAC TGAGGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Transcriptome-wide mapping reveals reversible and dynamic N(1)-methyladenosine methylome.
Nature chemical biology12(5)311-6(2016 May)
Li X,Xiong X,Wang K,Wang L,Shu X,Ma S,Yi C
The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA.
Nature530(7591)441-6(2016 Feb)
Dominissini D,Nachtergaele S,Moshitch-Moshkovitz S,Peer E,Kol N,Ben-Haim MS,Dai Q,Di Segni A,Salmon-Divon M,Clark WC,Zheng G,Pan T,Solomon O,Eyal E,Hershkovitz V,Han D,Doré LC,Amariglio N,Rechavi G,He C
DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.
Molecular cell44(3)373-84(2011 Nov)
Dango S,Mosammaparast N,Sowa ME,Xiong LJ,Wu F,Park K,Rubin M,Gygi S,Harper JW,Shi Y
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
The EMBO journal25(14)3389-97(2006 Jul)
Sundheim O,Vågbø CB,Bjørås M,Sousa MM,Talstad V,Aas PA,Drabløs F,Krokan HE,Tainer JA,Slupphaug G
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues.
The Journal of biological chemistry280(47)39448-59(2005 Nov)
Lee DH,Jin SG,Cai S,Chen Y,Pfeifer GP,O'Connor TR
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