Sirt2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sirt2
Entrez Gene ID	361532
Full Name	sirtuin 2
General protein information	Preferred Names sirtuin 2 Names NAD-dependent protein deacetylase sirtuin-2 5E5 antigen NAD-dependent deacetylase sirtuin-2 SIR2-like protein 2 regulatory protein SIR2 homolog 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
XM_006228675.2	XP_006228737.1	NAD-dependent protein deacetylase sirtuin-2 isoform X4
XM_006228672.3	XP_006228734.1	NAD-dependent protein deacetylase sirtuin-2 isoform X1
XM_006228676.3	XP_006228738.1	NAD-dependent protein deacetylase sirtuin-2 isoform X5
NM_001008368.1	NP_001008369.1	NAD-dependent protein deacetylase sirtuin-2
XM_006228673.3	XP_006228735.1	NAD-dependent protein deacetylase sirtuin-2 isoform X2
XM_017589353.1	XP_017444842.1	NAD-dependent protein deacetylase sirtuin-2 isoform X3

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002943	XP_311957.5
Schizosaccharomyces pombe (fission yeast)	hst2	NP_588147.1
Drosophila melanogaster (fruit fly)	Sirt2	NP_650880.2
Macaca mulatta (Rhesus monkey)	LOC100425019	XP_002801273.1
Pan troglodytes (chimpanzee)	SIRT2	XP_001168375.1
Danio rerio (zebrafish)	sirt2	NP_955890.1
Bos taurus (cattle)	SIRT2	NP_001107003.1
Mus musculus (house mouse)	Sirt2	NP_071877.3
Rattus norvegicus (Norway rat)	Sirt2	NP_001008369.1
Kluyveromyces lactis	KLLA0F11033g	XP_455583.1
Magnaporthe oryzae (rice blast fungus)	MGG_17827	XP_003720356.1
Canis lupus familiaris (dog)	SIRT2	XP_855382.2
Xenopus tropicalis (tropical clawed frog)	LOC100489469	XP_002935827.2
Eremothecium gossypii	AGOS_AGL018C	NP_986648.1
Neurospora crassa	NCU00523	XP_963725.2
Homo sapiens (human)	SIRT2	NP_036369.2
Gallus gallus (chicken)	SIRT2	NP_001017414.1
Saccharomyces cerevisiae (baker's yeast)	HST2	NP_015310.1

Gene Ontology
Bibliography

Related articles in PubMed

MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2.
Zhao L, Qi Y, Xu L, Tao X, Han X, Yin L, Peng J
Redox biology15284-296(2018 05)

Overexpression of SIRT2 Alleviates Neuropathic Pain and Neuroinflammation Through Deacetylation of Transcription Factor Nuclear Factor-Kappa B.
Zhang Y, Chi D
Inflammation41(2)569-578(2018 Mar)

The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats.
Keskin-Aktan A, Akbulut KG, Yazici-Mutlu Ç, Sonugur G, Ocal M, Akbulut H
Brain research bulletin137306-310(2018 03)

Crucial Roles for SIRT2 and AMPA Receptor Acetylation in Synaptic Plasticity and Memory.
Wang G, Li S, Gilbert J, Gritton HJ, Wang Z, Li Z, Han X, Selkoe DJ, Man HY
Cell reports20(6)1335-1347(2017 08)

SIRT2-mediated FOXO3a deacetylation drives its nuclear translocation triggering FasL-induced cell apoptosis during renal ischemia reperfusion.
Wang Y, Mu Y, Zhou X, Ji H, Gao X, Cai WW, Guan Q, Xu T
Apoptosis : an international journal on programmed cell death22(4)519-530(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sirt2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sirt2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11902	NM_001008368.1 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa22531	XM_006228672.3 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa22532	XM_006228673.3 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa22534	XM_006228675.2 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa22535	XM_006228676.3 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa56683	XM_017589353.1 Latest version!	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sirt2 ( NM_001008368.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008369.1 Rattus norvegicus sirtuin 2 (Sirt2), mRNA.

Price & Availability↑

CloneID	ORa11902
Clone ID Related Accession (Same CDS sequence)	NM_001008368.1
Accession Version	NM_001008368.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571414400000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC086545.1. On Dec 16, 2004 this sequence version replaced XM_341817.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC086545.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACTTCC TACGGAATTT ATTCACCCAG ACCCTGGGCC TGGGTTCCCA GAAGGAGCGT 
CTGCTGGACG AGCTGACCCT TGAAGGAGTG ACACGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACATCCG CAGGAATCCC TGACTTCCGC 
TCCCCATCCA CTGGCCTCTA TGCAAACTTG GAGAAATACC ACCTTCCATA CCCAGAGGCC 
ATCTTTGAGA TCAGCTACTT CAAGAAACAT CCAGAACCCT TCTTTGCCCT TGCTAAGGAG 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAG 
AAGGGGCTGC TGCTGCGCTG CTACACGCAG AATATTGACA CTCTGGAACG AGTGGCAGGG 
CTGGAGCCCC AGGACCTGGT GGAGGCCCAC GGCACCTTCT ACACATCACA CTGTGTCAAC 
ACCTCCTGTG GAAAAGAGTA CACGATGAGC TGGATGAAAG AGAAGATCTT CTCAGAAGCA 
ACTCCCAAGT GTGAGAAGTG TCAGAATGTG GTAAAGCCCG ATATCGTGTT TTTCGGTGAG 
AACCTCCCAC CGCGCTTCTT CTCCTGCATG CAGTCAGACT TCTCAAAGGT GGACCTCCTC 
ATCATCATGG GCACCTCCCT GCAGGTGCAG CCCTTCGCCT CCCTCATCAG CAAGGCACCA 
CTAGCCACCC CACGACTGCT CATTAACAAG GAGAAGACAG GCCAGACGGA TCCCTTCCTG 
GGCATGATGA TGGGCTTGGG AGGCGGCATG GATTTTGACT CCAAGAAGGC TTACAGGGAC 
GTGGCCTGGC TGGGTGACTG TGACCAAGGC TGCCTGGCTC TCGCTGACCT CCTGGGATGG 
AAGGAGCTGG AAGACCTTGT CCGGAGGGAG CATGCCAACA TAGATGCCCA GTCAGGGTCA 
CAGGCCTCCA ACCCCAGCGC TACCGTCTCC CCTAGAAAGT CCCCACCTCC TGCCAAGGAG 
GCGGCCAGGA CCAAAGAGAA AGAGGAACAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008369.1
CDS	467..1519
Translation	MDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	NM_001008368.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008368.1

ORF Insert Sequence:

ATGGACTTCC TACGGAATTT ATTCACCCAG ACCCTGGGCC TGGGTTCCCA GAAGGAGCGT 
CTGCTGGACG AGCTGACCCT TGAAGGAGTG ACACGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACATCCG CAGGAATCCC TGACTTCCGC 
TCCCCATCCA CTGGCCTCTA TGCAAACTTG GAGAAATACC ACCTTCCATA CCCAGAGGCC 
ATCTTTGAGA TCAGCTACTT CAAGAAACAT CCAGAACCCT TCTTTGCCCT TGCTAAGGAG 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAG 
AAGGGGCTGC TGCTGCGCTG CTACACGCAG AATATTGACA CTCTGGAACG AGTGGCAGGG 
CTGGAGCCCC AGGACCTGGT GGAGGCCCAC GGCACCTTCT ACACATCACA CTGTGTCAAC 
ACCTCCTGTG GAAAAGAGTA CACGATGAGC TGGATGAAAG AGAAGATCTT CTCAGAAGCA 
ACTCCCAAGT GTGAGAAGTG TCAGAATGTG GTAAAGCCCG ATATCGTGTT TTTCGGTGAG 
AACCTCCCAC CGCGCTTCTT CTCCTGCATG CAGTCAGACT TCTCAAAGGT GGACCTCCTC 
ATCATCATGG GCACCTCCCT GCAGGTGCAG CCCTTCGCCT CCCTCATCAG CAAGGCACCA 
CTAGCCACCC CACGACTGCT CATTAACAAG GAGAAGACAG GCCAGACGGA TCCCTTCCTG 
GGCATGATGA TGGGCTTGGG AGGCGGCATG GATTTTGACT CCAAGAAGGC TTACAGGGAC 
GTGGCCTGGC TGGGTGACTG TGACCAAGGC TGCCTGGCTC TCGCTGACCT CCTGGGATGG 
AAGGAGCTGG AAGACCTTGT CCGGAGGGAG CATGCCAACA TAGATGCCCA GTCAGGGTCA 
CAGGCCTCCA ACCCCAGCGC TACCGTCTCC CCTAGAAAGT CCCCACCTCC TGCCAAGGAG 
GCGGCCAGGA CCAAAGAGAA AGAGGAACAC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt2 ( XM_006228672.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228734.1 Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22531
Clone ID Related Accession (Same CDS sequence)	XM_006228672.3
Accession Version	XM_006228672.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228672.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGCGG TTACGGGACC GCGTTGCCTG TCGGGAGTTG TATTTTTCTA TCCTCTCTCG 
GCTCCTTCTT GTTTCCGCTG CCGTCACGGG ACAGAGCAGT CGGTGACAGT CCCGAGAGCC 
CCCACCCCGT TCCCATGGCC GAGCCGGACC GATTCAGACT CGGACACTGA GGGAGGAGCC 
ACTGGCGGAG AGGCAGAGAT GGACTTCCTA CGGAATTTAT TCACCCAGAC CCTGGGCCTG 
GGTTCCCAGA AGGAGCGTCT GCTGGACGAG CTGACCCTTG AAGGAGTGAC ACGCTACATG 
CAGAGCGAGC GCTGTCGCAG GGTCATCTGT TTGGTGGGAG CTGGAATCTC CACATCCGCA 
GGAATCCCTG ACTTCCGCTC CCCATCCACT GGCCTCTATG CAAACTTGGA GAAATACCAC 
CTTCCATACC CAGAGGCCAT CTTTGAGATC AGCTACTTCA AGAAACATCC AGAACCCTTC 
TTTGCCCTTG CTAAGGAGCT CTATCCTGGG CAGTTCAAGC CGACCATCTG CCACTACTTC 
ATCCGCCTGC TGAAGGAGAA GGGGCTGCTG CTGCGCTGCT ACACGCAGAA TATTGACACT 
CTGGAACGAG TGGCAGGGCT GGAGCCCCAG GACCTGGTGG AGGCCCACGG CACCTTCTAC 
ACATCACACT GTGTCAACAC CTCCTGTGGA AAAGAGTACA CGATGAGCTG GATGAAAGAG 
AAGATCTTCT CAGAAGCAAC TCCCAAGTGT GAGAAGTGTC AGAATGTGGT AAAGCCCGGT 
GAGCCTCAGA CCCCTTTCTT CCACTGGCCC GCACGCACCT CAAATCTGGC CACTCTGCTA 
CCTGGCCTGT CCCCTACTGT TCTGCAGAGA GTGGGTATCT GTCTGCCCTT CCCCCCCCAC 
CCCTGCCCCA GTTGGGCCCC AACTCCTGCC TGTTTTAGCT CTGTCCCCCA TGTCTCCTCT 
CCTCTGTCCC TGTGTCTCTC TGTTTCCACC TCAGATATCG TGTTTTTCGG TGAGAACCTC 
CCACCGCGCT TCTTCTCCTG CATGCAGTCA GACTTCTCAA AGGTGGACCT CCTCATCATC 
ATGGGCACCT CCCTGCAGGT GCAGCCCTTC GCCTCCCTCA TCAGCAAGGC ACCACTAGCC 
ACCCCACGAC TGCTCATTAA CAAGGAGAAG ACAGGCCAGA CGGATCCCTT CCTGGGCATG 
ATGATGGGCT TGGGAGGCGG CATGGATTTT GACTCCAAGA AGGCTTACAG GGACGTGGCC 
TGGCTGGGTG ACTGTGACCA AGGCTGCCTG GCTCTCGCTG ACCTCCTGGG ATGGAAGAAG 
GAGCTGGAAG ACCTTGTCCG GAGGGAGCAT GCCAACATAG ATGCCCAGTC AGGGTCACAG 
GCCTCCAACC CCAGCGCTAC CGTCTCCCCT AGAAAGTCCC CACCTCCTGC CAAGGAGGCG 
GCCAGGACCA AAGAGAAAGA GGAACACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228734.1
CDS	16..1485
Translation	MKAVTGPRCLSGVVFFYPLSAPSCFRCRHGTEQSVTVPRAPTPFPWPSRTDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPGEPQTPFFHWPARTSNLATLLPGLSPTVLQRVGICLPFPPHPCPSWAPTPACFSSVPHVSSPLSLCLSVSTSDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	XM_006228672.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228672.3

ORF Insert Sequence:

ATGAAAGCGG TTACGGGACC GCGTTGCCTG TCGGGAGTTG TATTTTTCTA TCCTCTCTCG 
GCTCCTTCTT GTTTCCGCTG CCGTCACGGG ACAGAGCAGT CGGTGACAGT CCCGAGAGCC 
CCCACCCCGT TCCCATGGCC GAGCCGGACC GATTCAGACT CGGACACTGA GGGAGGAGCC 
ACTGGCGGAG AGGCAGAGAT GGACTTCCTA CGGAATTTAT TCACCCAGAC CCTGGGCCTG 
GGTTCCCAGA AGGAGCGTCT GCTGGACGAG CTGACCCTTG AAGGAGTGAC ACGCTACATG 
CAGAGCGAGC GCTGTCGCAG GGTCATCTGT TTGGTGGGAG CTGGAATCTC CACATCCGCA 
GGAATCCCTG ACTTCCGCTC CCCATCCACT GGCCTCTATG CAAACTTGGA GAAATACCAC 
CTTCCATACC CAGAGGCCAT CTTTGAGATC AGCTACTTCA AGAAACATCC AGAACCCTTC 
TTTGCCCTTG CTAAGGAGCT CTATCCTGGG CAGTTCAAGC CGACCATCTG CCACTACTTC 
ATCCGCCTGC TGAAGGAGAA GGGGCTGCTG CTGCGCTGCT ACACGCAGAA TATTGACACT 
CTGGAACGAG TGGCAGGGCT GGAGCCCCAG GACCTGGTGG AGGCCCACGG CACCTTCTAC 
ACATCACACT GTGTCAACAC CTCCTGTGGA AAAGAGTACA CGATGAGCTG GATGAAAGAG 
AAGATCTTCT CAGAAGCAAC TCCCAAGTGT GAGAAGTGTC AGAATGTGGT AAAGCCCGGT 
GAGCCTCAGA CCCCTTTCTT CCACTGGCCC GCACGCACCT CAAATCTGGC CACTCTGCTA 
CCTGGCCTGT CCCCTACTGT TCTGCAGAGA GTGGGTATCT GTCTGCCCTT CCCCCCCCAC 
CCCTGCCCCA GTTGGGCCCC AACTCCTGCC TGTTTTAGCT CTGTCCCCCA TGTCTCCTCT 
CCTCTGTCCC TGTGTCTCTC TGTTTCCACC TCAGATATCG TGTTTTTCGG TGAGAACCTC 
CCACCGCGCT TCTTCTCCTG CATGCAGTCA GACTTCTCAA AGGTGGACCT CCTCATCATC 
ATGGGCACCT CCCTGCAGGT GCAGCCCTTC GCCTCCCTCA TCAGCAAGGC ACCACTAGCC 
ACCCCACGAC TGCTCATTAA CAAGGAGAAG ACAGGCCAGA CGGATCCCTT CCTGGGCATG 
ATGATGGGCT TGGGAGGCGG CATGGATTTT GACTCCAAGA AGGCTTACAG GGACGTGGCC 
TGGCTGGGTG ACTGTGACCA AGGCTGCCTG GCTCTCGCTG ACCTCCTGGG ATGGAAGAAG 
GAGCTGGAAG ACCTTGTCCG GAGGGAGCAT GCCAACATAG ATGCCCAGTC AGGGTCACAG 
GCCTCCAACC CCAGCGCTAC CGTCTCCCCT AGAAAGTCCC CACCTCCTGC CAAGGAGGCG 
GCCAGGACCA AAGAGAAAGA GGAACACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt2 ( XM_006228673.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228735.1 Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa22532
Clone ID Related Accession (Same CDS sequence)	XM_006228673.3
Accession Version	XM_006228673.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228673.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGAGC CGGACCCCTC TGACCCTCTG GAGAACCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGATTCAG ACTCGGACAC TGAGGGAGGA GCCACTGGCG GAGAGGCAGA GATGGACTTC 
CTACGGAATT TATTCACCCA GACCCTGGGC CTGGGTTCCC AGAAGGAGCG TCTGCTGGAC 
GAGCTGACCC TTGAAGGAGT GACACGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACATCC GCAGGAATCC CTGACTTCCG CTCCCCATCC 
ACTGGCCTCT ATGCAAACTT GGAGAAATAC CACCTTCCAT ACCCAGAGGC CATCTTTGAG 
ATCAGCTACT TCAAGAAACA TCCAGAACCC TTCTTTGCCC TTGCTAAGGA GCTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA GAAGGGGCTG 
CTGCTGCGCT GCTACACGCA GAATATTGAC ACTCTGGAAC GAGTGGCAGG GCTGGAGCCC 
CAGGACCTGG TGGAGGCCCA CGGCACCTTC TACACATCAC ACTGTGTCAA CACCTCCTGT 
GGAAAAGAGT ACACGATGAG CTGGATGAAA GAGAAGATCT TCTCAGAAGC AACTCCCAAG 
TGTGAGAAGT GTCAGAATGT GGTAAAGCCC GGTGAGCCTC AGACCCCTTT CTTCCACTGG 
CCCGCACGCA CCTCAAATCT GGCCACTCTG CTACCTGGCC TGTCCCCTAC TGTTCTGCAG 
AGAGTGGGTA TCTGTCTGCC CTTCCCCCCC CACCCCTGCC CCAGTTGGGC CCCAACTCCT 
GCCTGTTTTA GCTCTGTCCC CCATGTCTCC TCTCCTCTGT CCCTGTGTCT CTCTGTTTCC 
ACCTCAGATA TCGTGTTTTT CGGTGAGAAC CTCCCACCGC GCTTCTTCTC CTGCATGCAG 
TCAGACTTCT CAAAGGTGGA CCTCCTCATC ATCATGGGCA CCTCCCTGCA GGTGCAGCCC 
TTCGCCTCCC TCATCAGCAA GGCACCACTA GCCACCCCAC GACTGCTCAT TAACAAGGAG 
AAGACAGGCC AGACGGATCC CTTCCTGGGC ATGATGATGG GCTTGGGAGG CGGCATGGAT 
TTTGACTCCA AGAAGGCTTA CAGGGACGTG GCCTGGCTGG GTGACTGTGA CCAAGGCTGC 
CTGGCTCTCG CTGACCTCCT GGGATGGAAG AAGGAGCTGG AAGACCTTGT CCGGAGGGAG 
CATGCCAACA TAGATGCCCA GTCAGGGTCA CAGGCCTCCA ACCCCAGCGC TACCGTCTCC 
CCTAGAAAGT CCCCACCTCC TGCCAAGGAG GCGGCCAGGA CCAAAGAGAA AGAGGAACAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228735.1
CDS	103..1485
Translation	MAEPDPSDPLENQAGKVQEAQDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPGEPQTPFFHWPARTSNLATLLPGLSPTVLQRVGICLPFPPHPCPSWAPTPACFSSVPHVSSPLSLCLSVSTSDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	XM_006228673.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228673.3

ORF Insert Sequence:

ATGGCCGAGC CGGACCCCTC TGACCCTCTG GAGAACCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGATTCAG ACTCGGACAC TGAGGGAGGA GCCACTGGCG GAGAGGCAGA GATGGACTTC 
CTACGGAATT TATTCACCCA GACCCTGGGC CTGGGTTCCC AGAAGGAGCG TCTGCTGGAC 
GAGCTGACCC TTGAAGGAGT GACACGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACATCC GCAGGAATCC CTGACTTCCG CTCCCCATCC 
ACTGGCCTCT ATGCAAACTT GGAGAAATAC CACCTTCCAT ACCCAGAGGC CATCTTTGAG 
ATCAGCTACT TCAAGAAACA TCCAGAACCC TTCTTTGCCC TTGCTAAGGA GCTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA GAAGGGGCTG 
CTGCTGCGCT GCTACACGCA GAATATTGAC ACTCTGGAAC GAGTGGCAGG GCTGGAGCCC 
CAGGACCTGG TGGAGGCCCA CGGCACCTTC TACACATCAC ACTGTGTCAA CACCTCCTGT 
GGAAAAGAGT ACACGATGAG CTGGATGAAA GAGAAGATCT TCTCAGAAGC AACTCCCAAG 
TGTGAGAAGT GTCAGAATGT GGTAAAGCCC GGTGAGCCTC AGACCCCTTT CTTCCACTGG 
CCCGCACGCA CCTCAAATCT GGCCACTCTG CTACCTGGCC TGTCCCCTAC TGTTCTGCAG 
AGAGTGGGTA TCTGTCTGCC CTTCCCCCCC CACCCCTGCC CCAGTTGGGC CCCAACTCCT 
GCCTGTTTTA GCTCTGTCCC CCATGTCTCC TCTCCTCTGT CCCTGTGTCT CTCTGTTTCC 
ACCTCAGATA TCGTGTTTTT CGGTGAGAAC CTCCCACCGC GCTTCTTCTC CTGCATGCAG 
TCAGACTTCT CAAAGGTGGA CCTCCTCATC ATCATGGGCA CCTCCCTGCA GGTGCAGCCC 
TTCGCCTCCC TCATCAGCAA GGCACCACTA GCCACCCCAC GACTGCTCAT TAACAAGGAG 
AAGACAGGCC AGACGGATCC CTTCCTGGGC ATGATGATGG GCTTGGGAGG CGGCATGGAT 
TTTGACTCCA AGAAGGCTTA CAGGGACGTG GCCTGGCTGG GTGACTGTGA CCAAGGCTGC 
CTGGCTCTCG CTGACCTCCT GGGATGGAAG AAGGAGCTGG AAGACCTTGT CCGGAGGGAG 
CATGCCAACA TAGATGCCCA GTCAGGGTCA CAGGCCTCCA ACCCCAGCGC TACCGTCTCC 
CCTAGAAAGT CCCCACCTCC TGCCAAGGAG GCGGCCAGGA CCAAAGAGAA AGAGGAACAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt2 ( XM_006228675.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228737.1 Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X4, mRNA.

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CloneID	ORa22534
Clone ID Related Accession (Same CDS sequence)	XM_006228675.2
Accession Version	XM_006228675.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228675.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGCGG TTACGGGACC GCGTTGCCTG TCGGGAGTTG TATTTTTCTA TCCTCTCTCG 
GCTCCTTCTT GTTTCCGCTG CCGTCACGGG ACAGAGCAGT CGGTGACAGT CCCGAGAGCC 
CCCACCCCGT TCCCATGGCC GAGCCGGACC GATTCAGACT CGGACACTGA GGGAGGAGCC 
ACTGGCGGAG AGGCAGAGAT GGACTTCCTA CGGAATTTAT TCACCCAGAC CCTGGGCCTG 
GGTTCCCAGA AGGAGCGTCT GCTGGACGAG CTGACCCTTG AAGGAGTGAC ACGCTACATG 
CAGAGCGAGC GCTGTCGCAG GGTCATCTGT TTGGTGGGAG CTGGAATCTC CACATCCGCA 
GGAATCCCTG ACTTCCGCTC CCCATCCACT GGCCTCTATG CAAACTTGGA GAAATACCAC 
CTTCCATACC CAGAGGCCAT CTTTGAGATC AGCTACTTCA AGAAACATCC AGAACCCTTC 
TTTGCCCTTG CTAAGGAGCT CTATCCTGGG CAGTTCAAGC CGACCATCTG CCACTACTTC 
ATCCGCCTGC TGAAGGAGAA GGGGCTGCTG CTGCGCTGCT ACACGCAGAA TATTGACACT 
CTGGAACGAG TGGCAGGGCT GGAGCCCCAG GACCTGGTGG AGGCCCACGG CACCTTCTAC 
ACATCACACT GTGTCAACAC CTCCTGTGGA AAAGAGTACA CGATGAGCTG GATGAAAGAG 
AAGATCTTCT CAGAAGCAAC TCCCAAGTGT GAGAAGTGTC AGAATGTGGT AAAGCCCGAT 
ATCGTGTTTT TCGGTGAGAA CCTCCCACCG CGCTTCTTCT CCTGCATGCA GTCAGACTTC 
TCAAAGGTGG ACCTCCTCAT CATCATGGGC ACCTCCCTGC AGGTGCAGCC CTTCGCCTCC 
CTCATCAGCA AGGCACCACT AGCCACCCCA CGACTGCTCA TTAACAAGGA GAAGACAGGC 
CAGACGGATC CCTTCCTGGG CATGATGATG GGCTTGGGAG GCGGCATGGA TTTTGACTCC 
AAGAAGGCTT ACAGGGACGT GGCCTGGCTG GGTGACTGTG ACCAAGGCTG CCTGGCTCTC 
GCTGACCTCC TGGGATGGAA GAAGGAGCTG GAAGACCTTG TCCGGAGGGA GCATGCCAAC 
ATAGATGCCC AGTCAGGGTC ACAGGCCTCC AACCCCAGCG CTACCGTCTC CCCTAGAAAG 
TCCCCACCTC CTGCCAAGGA GGCGGCCAGG ACCAAAGAGA AAGAGGAACA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228737.1
CDS	16..1269
Translation	MKAVTGPRCLSGVVFFYPLSAPSCFRCRHGTEQSVTVPRAPTPFPWPSRTDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	XM_006228675.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228675.2

ORF Insert Sequence:

ATGAAAGCGG TTACGGGACC GCGTTGCCTG TCGGGAGTTG TATTTTTCTA TCCTCTCTCG 
GCTCCTTCTT GTTTCCGCTG CCGTCACGGG ACAGAGCAGT CGGTGACAGT CCCGAGAGCC 
CCCACCCCGT TCCCATGGCC GAGCCGGACC GATTCAGACT CGGACACTGA GGGAGGAGCC 
ACTGGCGGAG AGGCAGAGAT GGACTTCCTA CGGAATTTAT TCACCCAGAC CCTGGGCCTG 
GGTTCCCAGA AGGAGCGTCT GCTGGACGAG CTGACCCTTG AAGGAGTGAC ACGCTACATG 
CAGAGCGAGC GCTGTCGCAG GGTCATCTGT TTGGTGGGAG CTGGAATCTC CACATCCGCA 
GGAATCCCTG ACTTCCGCTC CCCATCCACT GGCCTCTATG CAAACTTGGA GAAATACCAC 
CTTCCATACC CAGAGGCCAT CTTTGAGATC AGCTACTTCA AGAAACATCC AGAACCCTTC 
TTTGCCCTTG CTAAGGAGCT CTATCCTGGG CAGTTCAAGC CGACCATCTG CCACTACTTC 
ATCCGCCTGC TGAAGGAGAA GGGGCTGCTG CTGCGCTGCT ACACGCAGAA TATTGACACT 
CTGGAACGAG TGGCAGGGCT GGAGCCCCAG GACCTGGTGG AGGCCCACGG CACCTTCTAC 
ACATCACACT GTGTCAACAC CTCCTGTGGA AAAGAGTACA CGATGAGCTG GATGAAAGAG 
AAGATCTTCT CAGAAGCAAC TCCCAAGTGT GAGAAGTGTC AGAATGTGGT AAAGCCCGAT 
ATCGTGTTTT TCGGTGAGAA CCTCCCACCG CGCTTCTTCT CCTGCATGCA GTCAGACTTC 
TCAAAGGTGG ACCTCCTCAT CATCATGGGC ACCTCCCTGC AGGTGCAGCC CTTCGCCTCC 
CTCATCAGCA AGGCACCACT AGCCACCCCA CGACTGCTCA TTAACAAGGA GAAGACAGGC 
CAGACGGATC CCTTCCTGGG CATGATGATG GGCTTGGGAG GCGGCATGGA TTTTGACTCC 
AAGAAGGCTT ACAGGGACGT GGCCTGGCTG GGTGACTGTG ACCAAGGCTG CCTGGCTCTC 
GCTGACCTCC TGGGATGGAA GAAGGAGCTG GAAGACCTTG TCCGGAGGGA GCATGCCAAC 
ATAGATGCCC AGTCAGGGTC ACAGGCCTCC AACCCCAGCG CTACCGTCTC CCCTAGAAAG 
TCCCCACCTC CTGCCAAGGA GGCGGCCAGG ACCAAAGAGA AAGAGGAACA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt2 ( XM_006228676.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228738.1 Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X5, mRNA.

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CloneID	ORa22535
Clone ID Related Accession (Same CDS sequence)	XM_006228676.3
Accession Version	XM_006228676.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228676.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGAGC CGGACCCCTC TGACCCTCTG GAGAACCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGATTCAG ACTCGGACAC TGAGGGAGGA GCCACTGGCG GAGAGGCAGA GATGGACTTC 
CTACGGAATT TATTCACCCA GACCCTGGGC CTGGGTTCCC AGAAGGAGCG TCTGCTGGAC 
GAGCTGACCC TTGAAGGAGT GACACGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACATCC GCAGGAATCC CTGACTTCCG CTCCCCATCC 
ACTGGCCTCT ATGCAAACTT GGAGAAATAC CACCTTCCAT ACCCAGAGGC CATCTTTGAG 
ATCAGCTACT TCAAGAAACA TCCAGAACCC TTCTTTGCCC TTGCTAAGGA GCTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA GAAGGGGCTG 
CTGCTGCGCT GCTACACGCA GAATATTGAC ACTCTGGAAC GAGTGGCAGG GCTGGAGCCC 
CAGGACCTGG TGGAGGCCCA CGGCACCTTC TACACATCAC ACTGTGTCAA CACCTCCTGT 
GGAAAAGAGT ACACGATGAG CTGGATGAAA GAGAAGATCT TCTCAGAAGC AACTCCCAAG 
TGTGAGAAGT GTCAGAATGT GGTAAAGCCC GATATCGTGT TTTTCGGTGA GAACCTCCCA 
CCGCGCTTCT TCTCCTGCAT GCAGTCAGAC TTCTCAAAGG TGGACCTCCT CATCATCATG 
GGCACCTCCC TGCAGGTGCA GCCCTTCGCC TCCCTCATCA GCAAGGCACC ACTAGCCACC 
CCACGACTGC TCATTAACAA GGAGAAGACA GGCCAGACGG ATCCCTTCCT GGGCATGATG 
ATGGGCTTGG GAGGCGGCAT GGATTTTGAC TCCAAGAAGG CTTACAGGGA CGTGGCCTGG 
CTGGGTGACT GTGACCAAGG CTGCCTGGCT CTCGCTGACC TCCTGGGATG GAAGAAGGAG 
CTGGAAGACC TTGTCCGGAG GGAGCATGCC AACATAGATG CCCAGTCAGG GTCACAGGCC 
TCCAACCCCA GCGCTACCGT CTCCCCTAGA AAGTCCCCAC CTCCTGCCAA GGAGGCGGCC 
AGGACCAAAG AGAAAGAGGA ACACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228738.1
CDS	103..1269
Translation	MAEPDPSDPLENQAGKVQEAQDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	XM_006228676.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228676.3

ORF Insert Sequence:

ATGGCCGAGC CGGACCCCTC TGACCCTCTG GAGAACCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGATTCAG ACTCGGACAC TGAGGGAGGA GCCACTGGCG GAGAGGCAGA GATGGACTTC 
CTACGGAATT TATTCACCCA GACCCTGGGC CTGGGTTCCC AGAAGGAGCG TCTGCTGGAC 
GAGCTGACCC TTGAAGGAGT GACACGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACATCC GCAGGAATCC CTGACTTCCG CTCCCCATCC 
ACTGGCCTCT ATGCAAACTT GGAGAAATAC CACCTTCCAT ACCCAGAGGC CATCTTTGAG 
ATCAGCTACT TCAAGAAACA TCCAGAACCC TTCTTTGCCC TTGCTAAGGA GCTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA GAAGGGGCTG 
CTGCTGCGCT GCTACACGCA GAATATTGAC ACTCTGGAAC GAGTGGCAGG GCTGGAGCCC 
CAGGACCTGG TGGAGGCCCA CGGCACCTTC TACACATCAC ACTGTGTCAA CACCTCCTGT 
GGAAAAGAGT ACACGATGAG CTGGATGAAA GAGAAGATCT TCTCAGAAGC AACTCCCAAG 
TGTGAGAAGT GTCAGAATGT GGTAAAGCCC GATATCGTGT TTTTCGGTGA GAACCTCCCA 
CCGCGCTTCT TCTCCTGCAT GCAGTCAGAC TTCTCAAAGG TGGACCTCCT CATCATCATG 
GGCACCTCCC TGCAGGTGCA GCCCTTCGCC TCCCTCATCA GCAAGGCACC ACTAGCCACC 
CCACGACTGC TCATTAACAA GGAGAAGACA GGCCAGACGG ATCCCTTCCT GGGCATGATG 
ATGGGCTTGG GAGGCGGCAT GGATTTTGAC TCCAAGAAGG CTTACAGGGA CGTGGCCTGG 
CTGGGTGACT GTGACCAAGG CTGCCTGGCT CTCGCTGACC TCCTGGGATG GAAGAAGGAG 
CTGGAAGACC TTGTCCGGAG GGAGCATGCC AACATAGATG CCCAGTCAGG GTCACAGGCC 
TCCAACCCCA GCGCTACCGT CTCCCCTAGA AAGTCCCCAC CTCCTGCCAA GGAGGCGGCC 
AGGACCAAAG AGAAAGAGGA ACACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sirt2 ( XM_017589353.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444842.1 Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa56683
Clone ID Related Accession (Same CDS sequence)	XM_017589353.1
Accession Version	XM_017589353.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCC TACGGAATTT ATTCACCCAG ACCCTGGGCC TGGGTTCCCA GAAGGAGCGT 
CTGCTGGACG AGCTGACCCT TGAAGGAGTG ACACGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACATCCG CAGGAATCCC TGACTTCCGC 
TCCCCATCCA CTGGCCTCTA TGCAAACTTG GAGAAATACC ACCTTCCATA CCCAGAGGCC 
ATCTTTGAGA TCAGCTACTT CAAGAAACAT CCAGAACCCT TCTTTGCCCT TGCTAAGGAG 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAG 
AAGGGGCTGC TGCTGCGCTG CTACACGCAG AATATTGACA CTCTGGAACG AGTGGCAGGG 
CTGGAGCCCC AGGACCTGGT GGAGGCCCAC GGCACCTTCT ACACATCACA CTGTGTCAAC 
ACCTCCTGTG GAAAAGAGTA CACGATGAGC TGGATGAAAG AGAAGATCTT CTCAGAAGCA 
ACTCCCAAGT GTGAGAAGTG TCAGAATGTG GTAAAGCCCG GTGAGCCTCA GACCCCTTTC 
TTCCACTGGC CCGCACGCAC CTCAAATCTG GCCACTCTGC TACCTGGCCT GTCCCCTACT 
GTTCTGCAGA GAGTGGGTAT CTGTCTGCCC TTCCCCCCCC ACCCCTGCCC CAGTTGGGCC 
CCAACTCCTG CCTGTTTTAG CTCTGTCCCC CATGTCTCCT CTCCTCTGTC CCTGTGTCTC 
TCTGTTTCCA CCTCAGATAT CGTGTTTTTC GGTGAGAACC TCCCACCGCG CTTCTTCTCC 
TGCATGCAGT CAGACTTCTC AAAGGTGGAC CTCCTCATCA TCATGGGCAC CTCCCTGCAG 
GTGCAGCCCT TCGCCTCCCT CATCAGCAAG GCACCACTAG CCACCCCACG ACTGCTCATT 
AACAAGGAGA AGACAGGCCA GACGGATCCC TTCCTGGGCA TGATGATGGG CTTGGGAGGC 
GGCATGGATT TTGACTCCAA GAAGGCTTAC AGGGACGTGG CCTGGCTGGG TGACTGTGAC 
CAAGGCTGCC TGGCTCTCGC TGACCTCCTG GGATGGAAGA AGGAGCTGGA AGACCTTGTC 
CGGAGGGAGC ATGCCAACAT AGATGCCCAG TCAGGGTCAC AGGCCTCCAA CCCCAGCGCT 
ACCGTCTCCC CTAGAAAGTC CCCACCTCCT GCCAAGGAGG CGGCCAGGAC CAAAGAGAAA 
GAGGAACACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444842.1
CDS	672..1943
Translation	MDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATPKCEKCQNVVKPGEPQTPFFHWPARTSNLATLLPGLSPTVLQRVGICLPFPPHPCPSWAPTPACFSSVPHVSSPLSLCLSVSTSDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTGQTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH

Target ORF information:

RefSeq Version	XM_017589353.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sirtuin 2 (Sirt2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589353.1

ORF Insert Sequence:

ATGGACTTCC TACGGAATTT ATTCACCCAG ACCCTGGGCC TGGGTTCCCA GAAGGAGCGT 
CTGCTGGACG AGCTGACCCT TGAAGGAGTG ACACGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACATCCG CAGGAATCCC TGACTTCCGC 
TCCCCATCCA CTGGCCTCTA TGCAAACTTG GAGAAATACC ACCTTCCATA CCCAGAGGCC 
ATCTTTGAGA TCAGCTACTT CAAGAAACAT CCAGAACCCT TCTTTGCCCT TGCTAAGGAG 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAG 
AAGGGGCTGC TGCTGCGCTG CTACACGCAG AATATTGACA CTCTGGAACG AGTGGCAGGG 
CTGGAGCCCC AGGACCTGGT GGAGGCCCAC GGCACCTTCT ACACATCACA CTGTGTCAAC 
ACCTCCTGTG GAAAAGAGTA CACGATGAGC TGGATGAAAG AGAAGATCTT CTCAGAAGCA 
ACTCCCAAGT GTGAGAAGTG TCAGAATGTG GTAAAGCCCG GTGAGCCTCA GACCCCTTTC 
TTCCACTGGC CCGCACGCAC CTCAAATCTG GCCACTCTGC TACCTGGCCT GTCCCCTACT 
GTTCTGCAGA GAGTGGGTAT CTGTCTGCCC TTCCCCCCCC ACCCCTGCCC CAGTTGGGCC 
CCAACTCCTG CCTGTTTTAG CTCTGTCCCC CATGTCTCCT CTCCTCTGTC CCTGTGTCTC 
TCTGTTTCCA CCTCAGATAT CGTGTTTTTC GGTGAGAACC TCCCACCGCG CTTCTTCTCC 
TGCATGCAGT CAGACTTCTC AAAGGTGGAC CTCCTCATCA TCATGGGCAC CTCCCTGCAG 
GTGCAGCCCT TCGCCTCCCT CATCAGCAAG GCACCACTAG CCACCCCACG ACTGCTCATT 
AACAAGGAGA AGACAGGCCA GACGGATCCC TTCCTGGGCA TGATGATGGG CTTGGGAGGC 
GGCATGGATT TTGACTCCAA GAAGGCTTAC AGGGACGTGG CCTGGCTGGG TGACTGTGAC 
CAAGGCTGCC TGGCTCTCGC TGACCTCCTG GGATGGAAGA AGGAGCTGGA AGACCTTGTC 
CGGAGGGAGC ATGCCAACAT AGATGCCCAG TCAGGGTCAC AGGCCTCCAA CCCCAGCGCT 
ACCGTCTCCC CTAGAAAGTC CCCACCTCCT GCCAAGGAGG CGGCCAGGAC CAAAGAGAAA 
GAGGAACACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2.
Redox biology15284-296(2018 05)
Zhao L,Qi Y,Xu L,Tao X,Han X,Yin L,Peng J

Overexpression of SIRT2 Alleviates Neuropathic Pain and Neuroinflammation Through Deacetylation of Transcription Factor Nuclear Factor-Kappa B.
Inflammation41(2)569-578(2018 Mar)
Zhang Y,Chi D

The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats.
Brain research bulletin137306-310(2018 03)
Keskin-Aktan A,Akbulut KG,Yazici-Mutlu Ç,Sonugur G,Ocal M,Akbulut H

Crucial Roles for SIRT2 and AMPA Receptor Acetylation in Synaptic Plasticity and Memory.
Cell reports20(6)1335-1347(2017 08)
Wang G,Li S,Gilbert J,Gritton HJ,Wang Z,Li Z,Han X,Selkoe DJ,Man HY

SIRT2-mediated FOXO3a deacetylation drives its nuclear translocation triggering FasL-induced cell apoptosis during renal ischemia reperfusion.
Apoptosis : an international journal on programmed cell death22(4)519-530(2017 Apr)
Wang Y,Mu Y,Zhou X,Ji H,Gao X,Cai WW,Guan Q,Xu T

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Sirt2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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