Fam107a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fam107a
Entrez Gene ID	361018
Full Name	family with sequence similarity 107, member A
Synonyms	Drr1,RGD1306327,Tu3a
General protein information	Preferred Names family with sequence similarity 107, member A Names protein FAM107A downregulated in renal cell carcinoma-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p14

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025129.1	NP_001020300.1	actin-associated protein FAM107A
XM_017599736.1	XP_017455225.1	protein FAM107A isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	FAM107A	NP_001076957.1
Mus musculus (house mouse)	Fam107a	NP_899010.1
Canis lupus familiaris (dog)	FAM107A	XP_003639820.1
Gallus gallus (chicken)	FAM107A	XP_004944701.1
Xenopus tropicalis (tropical clawed frog)	fam107a	NP_001121654.1
Homo sapiens (human)	FAM107A	NP_001269643.1
Pan troglodytes (chimpanzee)	FAM107A	NP_001092044.1
Rattus norvegicus (Norway rat)	Fam107a	NP_001020300.1
Danio rerio (zebrafish)	LOC794256	XP_001334192.3
Macaca mulatta (Rhesus monkey)	FAM107A	XP_001095220.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.
Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K
Oncogene36(41)5745-5756(2017 10)

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.
Schmidt MV, Schülke JP, Liebl C, Stiess M, Avrabos C, Bock J, Wochnik GM, Davies HA, Zimmermann N, Scharf SH, Trümbach D, Wurst W, Zieglgänsberger W, Turck C, Holsboer F, Stewart MG, Bradke F, Eder M, Müller MB, Rein T
Proceedings of the National Academy of Sciences of the United States of America108(41)17213-8(2011 Oct)

DRR drives brain cancer invasion by regulating cytoskeletal-focal adhesion dynamics.
Le PU, Angers-Loustau A, de Oliveira RM, Ajlan A, Brassard CL, Dudley A, Brent H, Siu V, Trinh G, Mölenkamp G, Wang J, Seyed Sadr M, Bedell B, Del Maestro RF, Petrecca K
Oncogene29(33)4636-47(2010 Aug)

DRR1 is expressed in the developing nervous system and downregulated during neuroblastoma carcinogenesis.
Asano Y, Kishida S, Mu P, Sakamoto K, Murohara T, Kadomatsu K
Biochemical and biophysical research communications394(3)829-35(2010 Apr)

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA,
Proceedings of the National Academy of Sciences of the United States of America99(26)16899-903(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fam107a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fam107a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42149	NM_001025129.1 Latest version!	Rattus norvegicus family with sequence similarity 107, member A (Fam107a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa42149	XM_017599736.1 Latest version!	Rattus norvegicus family with sequence similarity 107, member A (Fam107a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fam107a ( NM_001025129.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020300.1 Rattus norvegicus family with sequence similarity 107, member A (Fam107a), mRNA.

Price & Availability↑

CloneID	ORa42149
Clone ID Related Accession (Same CDS sequence)	NM_001025129.1 , XM_017599736.1
Accession Version	NM_001025129.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	actin-associated protein FAM107A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC093601.1. On Jul 1, 2005 this sequence version replaced XM_341293.2. ##Evidence-Data-START## Transcript exon combination :: BC093601.1, FQ075380.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTACTCAG AGATCCAGAG GGAGCGGGCT GACATCGAGG GACTCATGGC CAGGCCAGAG 
TACAGAGAGT GGAATTCAGA GCTCATCAAA CCCAAGAAGC TGCTAAACCC TGTGAAGGCC 
TCTCGAAGCC ATCAGGAGCT GCACCGTGAG CTGCTTATGA ACCACAAAAG GGGCCTGGGT 
ATGGACCGCA AACCAGAATT GCAGCGGGTC CTGGAGCACC GTCGCAGGAA TCAGCTGATC 
AAAAAGAAGG AGGAGGAGCT GGAGGCCAAG CGGATGCAGT GCCCCTTCGA GCAGGAGCTG 
CTGAGAAGGC AGCAGAGACT GAACCAGCTG GAAAACCCAC CACAGAGAGA AGAGGACCAT 
GCCCCTGAGT TCATCAAAGT CCGGGAAAAC CTGCGCAGAA TCACCACCCT GACCAGCGAA 
GAGAGAGCAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020300.1
CDS	55..489
Translation	MYSEIQRERADIEGLMARPEYREWNSELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGMDRKPELQRVLEHRRRNQLIKKKEEELEAKRMQCPFEQELLRRQQRLNQLENPPQREEDHAPEFIKVRENLRRITTLTSEERAL

Target ORF information:

RefSeq Version	NM_001025129.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus family with sequence similarity 107, member A (Fam107a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025129.1

ORF Insert Sequence:

ATGTACTCAG AGATCCAGAG GGAGCGGGCT GACATCGAGG GACTCATGGC CAGGCCAGAG 
TACAGAGAGT GGAATTCAGA GCTCATCAAA CCCAAGAAGC TGCTAAACCC TGTGAAGGCC 
TCTCGAAGCC ATCAGGAGCT GCACCGTGAG CTGCTTATGA ACCACAAAAG GGGCCTGGGT 
ATGGACCGCA AACCAGAATT GCAGCGGGTC CTGGAGCACC GTCGCAGGAA TCAGCTGATC 
AAAAAGAAGG AGGAGGAGCT GGAGGCCAAG CGGATGCAGT GCCCCTTCGA GCAGGAGCTG 
CTGAGAAGGC AGCAGAGACT GAACCAGCTG GAAAACCCAC CACAGAGAGA AGAGGACCAT 
GCCCCTGAGT TCATCAAAGT CCGGGAAAAC CTGCGCAGAA TCACCACCCT GACCAGCGAA 
GAGAGAGCAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fam107a ( XM_017599736.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455225.1 Rattus norvegicus family with sequence similarity 107, member A (Fam107a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42149
Clone ID Related Accession (Same CDS sequence)	NM_001025129.1 , XM_017599736.1
Accession Version	XM_017599736.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	protein FAM107A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) and transcript sequence (BC093601.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 57 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGTACTCAG AGATCCAGAG GGAGCGGGCT GACATCGAGG GACTCATGGC CAGGCCAGAG 
TACAGAGAGT GGAATTCAGA GCTCATCAAA CCCAAGAAGC TGCTAAACCC TGTGAAGGCC 
TCTCGAAGCC ATCAGGAGCT GCACCGTGAG CTGCTTATGA ACCACAAAAG GGGCCTGGGT 
ATGGACCGCA AACCAGAATT GCAGCGGGTC CTGGAGCACC GTCGCAGGAA TCAGCTGATC 
AAAAAGAAGG AGGAGGAGCT GGAGGCCAAG CGGATGCAGT GCCCCTTCGA GCAGGAGCTG 
CTGAGAAGGC AGCAGAGACT GAACCAGCTG GAAAACCCAC CACAGAGAGA AGAGGACCAT 
GCCCCTGAGT TCATCAAAGT CCGGGAAAAC CTGCGCAGAA TCACCACCCT GACCAGCGAA 
GAGAGAGCAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455225.1
CDS	643..1077
Translation	MYSEIQRERADIEGLMARPEYREWNSELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGMDRKPELQRVLEHRRRNQLIKKKEEELEAKRMQCPFEQELLRRQQRLNQLENPPQREEDHAPEFIKVRENLRRITTLTSEERAL

Target ORF information:

RefSeq Version	XM_017599736.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus family with sequence similarity 107, member A (Fam107a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599736.1

ORF Insert Sequence:

ATGTACTCAG AGATCCAGAG GGAGCGGGCT GACATCGAGG GACTCATGGC CAGGCCAGAG 
TACAGAGAGT GGAATTCAGA GCTCATCAAA CCCAAGAAGC TGCTAAACCC TGTGAAGGCC 
TCTCGAAGCC ATCAGGAGCT GCACCGTGAG CTGCTTATGA ACCACAAAAG GGGCCTGGGT 
ATGGACCGCA AACCAGAATT GCAGCGGGTC CTGGAGCACC GTCGCAGGAA TCAGCTGATC 
AAAAAGAAGG AGGAGGAGCT GGAGGCCAAG CGGATGCAGT GCCCCTTCGA GCAGGAGCTG 
CTGAGAAGGC AGCAGAGACT GAACCAGCTG GAAAACCCAC CACAGAGAGA AGAGGACCAT 
GCCCCTGAGT TCATCAAAGT CCGGGAAAAC CTGCGCAGAA TCACCACCCT GACCAGCGAA 
GAGAGAGCAC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.
Oncogene36(41)5745-5756(2017 10)
Mu P,Akashi T,Lu F,Kishida S,Kadomatsu K

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition.
Proceedings of the National Academy of Sciences of the United States of America108(41)17213-8(2011 Oct)
Schmidt MV,Schülke JP,Liebl C,Stiess M,Avrabos C,Bock J,Wochnik GM,Davies HA,Zimmermann N,Scharf SH,Trümbach D,Wurst W,Zieglgänsberger W,Turck C,Holsboer F,Stewart MG,Bradke F,Eder M,Müller MB,Rein T

DRR drives brain cancer invasion by regulating cytoskeletal-focal adhesion dynamics.
Oncogene29(33)4636-47(2010 Aug)
Le PU,Angers-Loustau A,de Oliveira RM,Ajlan A,Brassard CL,Dudley A,Brent H,Siu V,Trinh G,Mölenkamp G,Wang J,Seyed Sadr M,Bedell B,Del Maestro RF,Petrecca K

DRR1 is expressed in the developing nervous system and downregulated during neuroblastoma carcinogenesis.
Biochemical and biophysical research communications394(3)829-35(2010 Apr)
Asano Y,Kishida S,Mu P,Sakamoto K,Murohara T,Kadomatsu K

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Proceedings of the National Academy of Sciences of the United States of America99(26)16899-903(2002 Dec)
Strausberg RL,Feingold EA,Grouse LH,Derge JG,Klausner RD,Collins FS,Wagner L,Shenmen CM,Schuler GD,Altschul SF,Zeeberg B,Buetow KH,Schaefer CF,Bhat NK,Hopkins RF,Jordan H,Moore T,Max SI,Wang J,Hsieh F,Diatchenko L,Marusina K,Farmer AA,Rubin GM,Hong L,Stapleton M,Soares MB,Bonaldo MF,Casavant TL,Scheetz TE,Brownstein MJ,Usdin TB,Toshiyuki S,Carninci P,Prange C,Raha SS,Loquellano NA,Peters GJ,Abramson RD,Mullahy SJ,Bosak SA,McEwan PJ,McKernan KJ,Malek JA,Gunaratne PH,Richards S,Worley KC,Hale S,Garcia AM,Gay LJ,Hulyk SW,Villalon DK,Muzny DM,Sodergren EJ,Lu X,Gibbs RA,Fahey J,Helton E,Ketteman M,Madan A,Rodrigues S,Sanchez A,Whiting M,Madan A,Young AC,Shevchenko Y,Bouffard GG,Blakesley RW,Touchman JW,Green ED,Dickson MC,Rodriguez AC,Grimwood J,Schmutz J,Myers RM,Butterfield YS,Krzywinski MI,Skalska U,Smailus DE,Schnerch A,Schein JE,Jones SJ,Marra MA,

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Fam107a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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