MAST1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAST1
Entrez Gene ID	353118
Full Name	microtubule associated serine/threonine kinase 1
Synonyms	Sast
General protein information	Preferred Names microtubule associated serine/threonine kinase 1 Names microtubule-associated serine/threonine-protein kinase 1 syntrophin associated serine/threonine kinase syntrophin-associated serine/threonine-protein kinase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19q11
Summary	interacts with syntrophin on the cell surface [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_181089.1	NP_851603.1	microtubule-associated serine/threonine-protein kinase 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MAST1	NP_001178457.1
Danio rerio (zebrafish)	LOC796144	XP_001336447.3
Xenopus tropicalis (tropical clawed frog)	mast1	XP_002938529.2
Pan troglodytes (chimpanzee)	MAST1	XP_003316199.2
Danio rerio (zebrafish)	mast1a	XP_001337128.3
Canis lupus familiaris (dog)	MAST1	XP_005633268.1
Rattus norvegicus (Norway rat)	MAST1	NP_851603.1
Homo sapiens (human)	MAST1	NP_055790.1
Macaca mulatta (Rhesus monkey)	MAST1	XP_001109914.2
Mus musculus (house mouse)	Mast1	NP_064329.2

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.
Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA
Neuron100(6)1354-1368.e5(2018 12)

Expression of the MAST family of serine/threonine kinases.
Garland P, Quraishe S, French P, O'Connor V
Brain research119512-9(2008 Feb)

Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions.
Yano R, Yap CC, Yamazaki Y, Muto Y, Kishida H, Okada D, Hashikawa T
Neuroscience117(2)373-81(2003)

Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.
Lumeng C, Phelps S, Crawford GE, Walden PD, Barald K, Chamberlain JS
Nature neuroscience2(7)611-7(1999 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAST1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAST1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04190	NM_181089.1 Latest version!	Rattus norvegicus microtubule associated serine/threonine kinase 1 (MAST1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAST1 ( NM_181089.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_851603.1 Rattus norvegicus microtubule associated serine/threonine kinase 1 (MAST1), mRNA.

Price & Availability↑

CloneID	ORa04190
Clone ID Related Accession (Same CDS sequence)	NM_181089.1
Accession Version	NM_181089.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	microtubule-associated serine/threonine-protein kinase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY227207.1. ##Evidence-Data-START## Transcript exon combination :: AY227207.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGACT CTCTCTGGAC CGCGCTTTCC AATTTCTCGA TGCCCTCCTT CCCCGGCGGC 
AGCATGTTTC GCCGCACCAA GAGCTGCCGT ACCAGTAACC GGAAAAGCCT CATCCTGACA 
AGCACTTCTC CGACGCTACC GCGACCCCAC TCCCCGCTGC CGGGTCACTT AGGTAGCAGT 
CCCCTGGACA GCCCCCGCAA CTTCTCTCCC AACACCCCTG CCCATTTCTC GTTTGCTTCT 
TCCCGAAGGG CGGATGGACG CCGGTGGTCC CTTGCTTCCC TTCCTTCCTC TGGATATGGC 
ACCAACACCC CAAGCTCAAC CGTCTCATCC TCCTGCTCCT CCCAGGAGCG CCTGCATCAA 
CTACCCTACC AGCCCACCGT GGACGAGTTG CACTTTCTGT CCAAACACTT CGGCAGCACC 
GAGAGCATCA CCGACGAAGA TGGTGGCCGC CGCTCCCCCG CCGTGCGTCC TCGCTCTCGG 
AGCCTCAGCC CCGGACGCTC CCCCTCCTCC TACGACAACG AAATCGTGAT GATGAACCAT 
GTGTACAAGG AGCGGTTCCC GAAGGCCACC GCGCAGATGG AAGAGAAGCT GCGGGACTTC 
GCCCGCGCCT ACGAACCTGA CAGCGTGCTG CCGCTGGCCG ACGGCGTGCT CAGCTTCATC 
CACCACCAGA TCATTGAACT GGCCCGAGAC TGCCTTACCA AGTCCCGCGA TGGGCTCATC 
ACCACGGTCT ATTTCTATGA ACTGCAGGAA AACCTAGAGA AGCTGCTGCA GGACGCCTAC 
GAACGCTCGG AGAGCCTGGA GGTGGCCTTC GTCACTCAGC TGGTGAAGAA ACTGCTCATC 
ATCATCTCTC GCCCTGCAAG GCTTCTGGAG TGCCTGGAAT TCAACCCAGA AGAATTCTAC 
CACCTGCTGG AGGCAGCGGA AGGCCACGCC AAGGAGGGCC ACCTGGTCAA AACTGACATC 
CCCCGATACA TCATCCGGCA GCTGGGCCTC ACTCGGGACC CCTTTCCAGA TGTGGTGCGC 
CTGGAGGAGC AGGACAGCGG GGGCTCCAAC ACGCCTGAAC AAGATGACAC GTCTGAGGGT 
CGCAGCAGCA CCTCCAAGGC CAAGAAACCT CCGGGTGAAA GTGACTTTGA CACTATCAAG 
CTCATAAGCA ATGGTGCCTA CGGGGCTGTC TACCTGGTGC GGCACCGGGA CACACGGCAG 
CGCTTTGCCA TGAAGAAGAT CAACAAACAG AACTTGATCC TTCGCAACCA GATCCAGCAG 
GCGTTCGTGG AGCGTGACAT CCTCACGTTT GCGGAGAACC CGTTTGTGGT CGGCATGTTC 
TGCTCCTTTG AGACCCGGCG CCATCTTTGC ATGGTCATGG AGTATGTGGA AGGTGGTGAC 
TGTGCCACTC TCCTGAAGAA CATTGGGGCA CTGCCTGTGG AGATGGCTCG AATGTATTTT 
GCAGAAACGG TTCTAGCTCT TGAATACTTA CACAATTATG GCATTGTGCA CCGTGACCTC 
AAGCCAGACA ACCTCCTCAT CACTTCCATG GGCCACATCA AACTCACGGA TTTTGGCCTC 
TCCAAGATGG GACTCATGAG CCTCACCACC AACTTATATG AAGGTCACAT TGAGAAAGAC 
GCCCGGGAGT TCCTGGACAA ACAGGTGTGT GGGACCCCGG AGTACATCGC ACCCGAGGTC 
ATCCTGCGCC AGGGCTACGG CAAGCCGGTG GACTGGTGGG CTATGGGCAT CATTCTCTAC 
GAGTTCCTGG TGGGCTGTGT GCCTTTCTTC GGGGATACCC CAGAAGAGCT CTTTGGACAG 
GTCATCAGTG ACGACATATT GTGGCCTGAA GGGGATGAGG CCCTGCCCAC AGACGCACAG 
CTTCTAATAT CTAGCCTCTT GCAGACCAAC CCCCTGGTCC GGCTTGGGGC AGGCGGTGCT 
TTTGAAGTAA AGCAGCATAG CTTCTTCCGA GACCTAGACT GGACGGGGCT ACTGAGGCAG 
AAGGCAGAGT TCATCCCCCA CCTAGAGTCA GAAGATGACA CCAGCTACTT TGACACCCGC 
TCCGACAGGT ATCACCATGT GAACTCTTAT GATGAGGACG ACACCACTGA GGAGGAGCCC 
GTGGAGATCC GCCAATTCTC CTCCTGCTCG CCGCGCTTCA GCAAGGTGTA CAGCAGTATG 
GAGCAGCTGT CTCAGCACGA GCCCAAGACT CCCGTCTCAG CATCTGGGGC TAGCAAGCGG 
GACCCAAATG CTAAGGGCCC GGAGGAGAAG GTGGCCGGAA AGAGGGAGGG ACTGGGTGGC 
CTGACTCTGC GTGAGAAGAC CTGGAGAGGG GGCTCTCCAG AGATTAAACG CTTCTCAGCA 
TCTGAAGCCA GTTTTCTGGA GGGAGAGGCC AGTCCCCCGC TGGGAGCGCG CAGACGGTTC 
TCAGCGCTAC TGGAGCCCAG CCGCTTCACT GCCCCTCAGG AGGATGAAGA TGAGGCCCGA 
CTCCGCAGAC CTCCTCGGCC CAGCTCTGAT CCCCCTAGCT CACTGGACAC ACGCGTCCCC 
AAAGAAGCAG CACAAGGAGA GGGCACATCC ACCCCGGGAG AACCCGAGGC CACTGAGCGC 
TCACATCCAG GTGACTTCTG CCCACCCTCC AAGGATGGAG ACCCGTCAGG TCCTAGGGCC 
ACCAATGATC TGGTTTTGCG AAGGGCGAGG CACCAGCAGC TGTCTGGGGA TCTCTCGGTG 
GAGAAGCGAC CGTCTCGAAC CGGGGGCAAA GTTATCAAGT CGGCGTCAGC TACAGCCTTG 
TCGGTCATGA TTCCTGCAGT GGACCCACAC GGAGGCTCAC CCCTGGCTAG TCCCATGTCC 
CCTCGATCTC TCTCCTCCAA TCCATCCTCT CGGGACTCTT CGCCTAGCCG AGACTACTCA 
CCAGCTGTCA GTGGACTCCG CTCCCCCATC ACCATCCAAC GCTCCGGCAA GAAATATGGC 
TTCACACTAC GAGCCATCCG TGTCTACATG GGCGACTCAG ATGTCTACAG TGTCCACCAC 
ATTGTTTGGC ACGTGGAGGA AGGAGGTCCA GCCCAAGAGG CAGGGCTCTG TGCTGGAGAC 
CTCATCACTC ACGTGAACGG TGAGCCTGTG CACGGTATGG TGCACCCTGA GGTGGTGGAG 
CTGATTCTAA AGAGTGGCAA CAAAGTAGCT GTGACCACCA CACCCTTTGA AAACACTTCC 
ATCCGGATTG GGCCGGCCAG GCGCAGCAGC TACAAAGCCA AAATGGCCCG CAGGAACAAG 
AGGCCTTCAG CTAAAGATGG CCAAGAGAGC AAGAAGCGGA GCTCCCTCTT CCGGAAGATC 
ACAAAACAGT CAAACCTGTT GCACACTAGC CGATCGCTGT CCTCTCTGAA CCGGTCTTTG 
TCGTCCAGCG ACAGTCTTCC TGGTTCGCCC ACGCACGGAC TACCCGCACG CTCGCCCACG 
CATAGCTATC GCTCCACACC TGACTCCGCC TACCTAGGTG CCTCGTCACA GAGTAGCTCT 
CCAGCTTCCA GCACACCTAA TTCCCCCGCC TCATCCGCCT CGCACCACAT CAGGCCCAGC 
ACTCTGCACG GGCTGTCACC GAAACTACAC CGCCAGTATC GTTCAGCGCG CTGTAAATCG 
GCTGGCAACA TCCCGCTGTC ACCTCTGGCG CACACTCCGT CCCCGACGCA GGCGTCGCCG 
CCGCCGCTGC CAGGCCACAC GGTGGGCAGC TCCCATACCA CGCAGAGCTT CCCTGCCAAA 
CTGCACTCAT CGCCGCCTAT CGTGCGTCCG CGCCCCAAAA GTGCAGAGCC ACCACGCTCG 
CCGTTGCTCA AGCGCGTGCA GTCAGCGGAA AAGCTAGGGG CTTCGCTGGG AGCAGACAAG 
AAGGGAGCAT TGCGCAAACA CAGTCTGGAA GTGGGTCACC CTGATTTCCG AAAGGACTTC 
CACGGTGAGC TGGCGCTGCA TAGCCTCGCT GAGTCCGATG GTGAGACGCC TCCTATTGAG 
GGTCCTGGGG CGACCCGGCA GGTCGCCATG AGACGCCTGG GCCGCCAGGA ATCTCCCCTA 
AGCTTGGGCG CGGACCCGTT GCTACCCGAT GGTGTCCAGA GACCTATGGC GTCAGGCAAG 
GAGGATTCCG CGGGAGGTAC AGAGGCTTGT ACTCCACCTC GCGCGACTAC CCCTGGGAGC 
CGGACCCTGG AGCGTGACTT GGGCTGCACA AGGCACCAGA GCGTGCAGAC TGAGGATGGC 
CCAGGTGGGG TGGCCAGAGC CCTGGCCAAG GCAGCGCTAA GCCCGGTGCA GGAACATGAG 
ACAGGCCGGC GCAGTAGCTC CGGTGAGGCA GGAACACCCC CGGTGCCCAT TGTTGTAGAG 
CCTGCCCGGC CAGGGGTCAA GACCCAGACA CCCCAGCCTC TGGGCACAGA CTCCAAGGGA 
TTGAAGGAAC CTGTAGCCCA GATCCCTCTG GTGCCTGATG CCCCAAGGGT CCGGGAGCGC 
TGGGTGCTAG AGGAGGTGGA AGAGCGGACC ACGTTAAGCG GACCTCGCTC TAAGCCCGCC 
TCCCCCAAAC TCTCTCCTGA CCCCCAGACT CCAACCGTAG CCCCAACAAA GAATGTACCC 
CGCAGTGCAG CTCCTCCAGT CCCACCTGCT TCCCTAATGG TCCCAGGTAC GAAGCCCGAA 
GCAGGGTCGA ACTCCCGGTG TCCTGCTGAA GGTGTGGCTT CAGCAGGCCT AACCAAAACG 
GGGGCACCCA GTCCTGCATC TTTAGGTCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_851603.1
CDS	1..4713
Translation	MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSSPLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLEEQDSGGSNTPEQDDTSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVSASGASKRDPNAKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASEASFLEGEASPPLGARRRFSALLEPSRFTAPQEDEDEARLRRPPRPSSDPPSSLDTRVPKEAAQGEGTSTPGEPEATERSHPGDFCPPSKDGDPSGPRATNDLVLRRARHQQLSGDLSVEKRPSRTGGKVIKSASATALSVMIPAVDPHGGSPLASPMSPRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRPSAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPIVRPRPKSAEPPRSPLLKRVQSAEKLGASLGADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPIEGPGATRQVAMRRLGRQESPLSLGADPLLPDGVQRPMASGKEDSAGGTEACTPPRATTPGSRTLERDLGCTRHQSVQTEDGPGGVARALAKAALSPVQEHETGRRSSSGEAGTPPVPIVVEPARPGVKTQTPQPLGTDSKGLKEPVAQIPLVPDAPRVRERWVLEEVEERTTLSGPRSKPASPKLSPDPQTPTVAPTKNVPRSAAPPVPPASLMVPGTKPEAGSNSRCPAEGVASAGLTKTGAPSPASLGP

Target ORF information:

RefSeq Version	NM_181089.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus microtubule associated serine/threonine kinase 1 (MAST1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181089.1

ORF Insert Sequence:

ATGTCTGACT CTCTCTGGAC CGCGCTTTCC AATTTCTCGA TGCCCTCCTT CCCCGGCGGC 
AGCATGTTTC GCCGCACCAA GAGCTGCCGT ACCAGTAACC GGAAAAGCCT CATCCTGACA 
AGCACTTCTC CGACGCTACC GCGACCCCAC TCCCCGCTGC CGGGTCACTT AGGTAGCAGT 
CCCCTGGACA GCCCCCGCAA CTTCTCTCCC AACACCCCTG CCCATTTCTC GTTTGCTTCT 
TCCCGAAGGG CGGATGGACG CCGGTGGTCC CTTGCTTCCC TTCCTTCCTC TGGATATGGC 
ACCAACACCC CAAGCTCAAC CGTCTCATCC TCCTGCTCCT CCCAGGAGCG CCTGCATCAA 
CTACCCTACC AGCCCACCGT GGACGAGTTG CACTTTCTGT CCAAACACTT CGGCAGCACC 
GAGAGCATCA CCGACGAAGA TGGTGGCCGC CGCTCCCCCG CCGTGCGTCC TCGCTCTCGG 
AGCCTCAGCC CCGGACGCTC CCCCTCCTCC TACGACAACG AAATCGTGAT GATGAACCAT 
GTGTACAAGG AGCGGTTCCC GAAGGCCACC GCGCAGATGG AAGAGAAGCT GCGGGACTTC 
GCCCGCGCCT ACGAACCTGA CAGCGTGCTG CCGCTGGCCG ACGGCGTGCT CAGCTTCATC 
CACCACCAGA TCATTGAACT GGCCCGAGAC TGCCTTACCA AGTCCCGCGA TGGGCTCATC 
ACCACGGTCT ATTTCTATGA ACTGCAGGAA AACCTAGAGA AGCTGCTGCA GGACGCCTAC 
GAACGCTCGG AGAGCCTGGA GGTGGCCTTC GTCACTCAGC TGGTGAAGAA ACTGCTCATC 
ATCATCTCTC GCCCTGCAAG GCTTCTGGAG TGCCTGGAAT TCAACCCAGA AGAATTCTAC 
CACCTGCTGG AGGCAGCGGA AGGCCACGCC AAGGAGGGCC ACCTGGTCAA AACTGACATC 
CCCCGATACA TCATCCGGCA GCTGGGCCTC ACTCGGGACC CCTTTCCAGA TGTGGTGCGC 
CTGGAGGAGC AGGACAGCGG GGGCTCCAAC ACGCCTGAAC AAGATGACAC GTCTGAGGGT 
CGCAGCAGCA CCTCCAAGGC CAAGAAACCT CCGGGTGAAA GTGACTTTGA CACTATCAAG 
CTCATAAGCA ATGGTGCCTA CGGGGCTGTC TACCTGGTGC GGCACCGGGA CACACGGCAG 
CGCTTTGCCA TGAAGAAGAT CAACAAACAG AACTTGATCC TTCGCAACCA GATCCAGCAG 
GCGTTCGTGG AGCGTGACAT CCTCACGTTT GCGGAGAACC CGTTTGTGGT CGGCATGTTC 
TGCTCCTTTG AGACCCGGCG CCATCTTTGC ATGGTCATGG AGTATGTGGA AGGTGGTGAC 
TGTGCCACTC TCCTGAAGAA CATTGGGGCA CTGCCTGTGG AGATGGCTCG AATGTATTTT 
GCAGAAACGG TTCTAGCTCT TGAATACTTA CACAATTATG GCATTGTGCA CCGTGACCTC 
AAGCCAGACA ACCTCCTCAT CACTTCCATG GGCCACATCA AACTCACGGA TTTTGGCCTC 
TCCAAGATGG GACTCATGAG CCTCACCACC AACTTATATG AAGGTCACAT TGAGAAAGAC 
GCCCGGGAGT TCCTGGACAA ACAGGTGTGT GGGACCCCGG AGTACATCGC ACCCGAGGTC 
ATCCTGCGCC AGGGCTACGG CAAGCCGGTG GACTGGTGGG CTATGGGCAT CATTCTCTAC 
GAGTTCCTGG TGGGCTGTGT GCCTTTCTTC GGGGATACCC CAGAAGAGCT CTTTGGACAG 
GTCATCAGTG ACGACATATT GTGGCCTGAA GGGGATGAGG CCCTGCCCAC AGACGCACAG 
CTTCTAATAT CTAGCCTCTT GCAGACCAAC CCCCTGGTCC GGCTTGGGGC AGGCGGTGCT 
TTTGAAGTAA AGCAGCATAG CTTCTTCCGA GACCTAGACT GGACGGGGCT ACTGAGGCAG 
AAGGCAGAGT TCATCCCCCA CCTAGAGTCA GAAGATGACA CCAGCTACTT TGACACCCGC 
TCCGACAGGT ATCACCATGT GAACTCTTAT GATGAGGACG ACACCACTGA GGAGGAGCCC 
GTGGAGATCC GCCAATTCTC CTCCTGCTCG CCGCGCTTCA GCAAGGTGTA CAGCAGTATG 
GAGCAGCTGT CTCAGCACGA GCCCAAGACT CCCGTCTCAG CATCTGGGGC TAGCAAGCGG 
GACCCAAATG CTAAGGGCCC GGAGGAGAAG GTGGCCGGAA AGAGGGAGGG ACTGGGTGGC 
CTGACTCTGC GTGAGAAGAC CTGGAGAGGG GGCTCTCCAG AGATTAAACG CTTCTCAGCA 
TCTGAAGCCA GTTTTCTGGA GGGAGAGGCC AGTCCCCCGC TGGGAGCGCG CAGACGGTTC 
TCAGCGCTAC TGGAGCCCAG CCGCTTCACT GCCCCTCAGG AGGATGAAGA TGAGGCCCGA 
CTCCGCAGAC CTCCTCGGCC CAGCTCTGAT CCCCCTAGCT CACTGGACAC ACGCGTCCCC 
AAAGAAGCAG CACAAGGAGA GGGCACATCC ACCCCGGGAG AACCCGAGGC CACTGAGCGC 
TCACATCCAG GTGACTTCTG CCCACCCTCC AAGGATGGAG ACCCGTCAGG TCCTAGGGCC 
ACCAATGATC TGGTTTTGCG AAGGGCGAGG CACCAGCAGC TGTCTGGGGA TCTCTCGGTG 
GAGAAGCGAC CGTCTCGAAC CGGGGGCAAA GTTATCAAGT CGGCGTCAGC TACAGCCTTG 
TCGGTCATGA TTCCTGCAGT GGACCCACAC GGAGGCTCAC CCCTGGCTAG TCCCATGTCC 
CCTCGATCTC TCTCCTCCAA TCCATCCTCT CGGGACTCTT CGCCTAGCCG AGACTACTCA 
CCAGCTGTCA GTGGACTCCG CTCCCCCATC ACCATCCAAC GCTCCGGCAA GAAATATGGC 
TTCACACTAC GAGCCATCCG TGTCTACATG GGCGACTCAG ATGTCTACAG TGTCCACCAC 
ATTGTTTGGC ACGTGGAGGA AGGAGGTCCA GCCCAAGAGG CAGGGCTCTG TGCTGGAGAC 
CTCATCACTC ACGTGAACGG TGAGCCTGTG CACGGTATGG TGCACCCTGA GGTGGTGGAG 
CTGATTCTAA AGAGTGGCAA CAAAGTAGCT GTGACCACCA CACCCTTTGA AAACACTTCC 
ATCCGGATTG GGCCGGCCAG GCGCAGCAGC TACAAAGCCA AAATGGCCCG CAGGAACAAG 
AGGCCTTCAG CTAAAGATGG CCAAGAGAGC AAGAAGCGGA GCTCCCTCTT CCGGAAGATC 
ACAAAACAGT CAAACCTGTT GCACACTAGC CGATCGCTGT CCTCTCTGAA CCGGTCTTTG 
TCGTCCAGCG ACAGTCTTCC TGGTTCGCCC ACGCACGGAC TACCCGCACG CTCGCCCACG 
CATAGCTATC GCTCCACACC TGACTCCGCC TACCTAGGTG CCTCGTCACA GAGTAGCTCT 
CCAGCTTCCA GCACACCTAA TTCCCCCGCC TCATCCGCCT CGCACCACAT CAGGCCCAGC 
ACTCTGCACG GGCTGTCACC GAAACTACAC CGCCAGTATC GTTCAGCGCG CTGTAAATCG 
GCTGGCAACA TCCCGCTGTC ACCTCTGGCG CACACTCCGT CCCCGACGCA GGCGTCGCCG 
CCGCCGCTGC CAGGCCACAC GGTGGGCAGC TCCCATACCA CGCAGAGCTT CCCTGCCAAA 
CTGCACTCAT CGCCGCCTAT CGTGCGTCCG CGCCCCAAAA GTGCAGAGCC ACCACGCTCG 
CCGTTGCTCA AGCGCGTGCA GTCAGCGGAA AAGCTAGGGG CTTCGCTGGG AGCAGACAAG 
AAGGGAGCAT TGCGCAAACA CAGTCTGGAA GTGGGTCACC CTGATTTCCG AAAGGACTTC 
CACGGTGAGC TGGCGCTGCA TAGCCTCGCT GAGTCCGATG GTGAGACGCC TCCTATTGAG 
GGTCCTGGGG CGACCCGGCA GGTCGCCATG AGACGCCTGG GCCGCCAGGA ATCTCCCCTA 
AGCTTGGGCG CGGACCCGTT GCTACCCGAT GGTGTCCAGA GACCTATGGC GTCAGGCAAG 
GAGGATTCCG CGGGAGGTAC AGAGGCTTGT ACTCCACCTC GCGCGACTAC CCCTGGGAGC 
CGGACCCTGG AGCGTGACTT GGGCTGCACA AGGCACCAGA GCGTGCAGAC TGAGGATGGC 
CCAGGTGGGG TGGCCAGAGC CCTGGCCAAG GCAGCGCTAA GCCCGGTGCA GGAACATGAG 
ACAGGCCGGC GCAGTAGCTC CGGTGAGGCA GGAACACCCC CGGTGCCCAT TGTTGTAGAG 
CCTGCCCGGC CAGGGGTCAA GACCCAGACA CCCCAGCCTC TGGGCACAGA CTCCAAGGGA 
TTGAAGGAAC CTGTAGCCCA GATCCCTCTG GTGCCTGATG CCCCAAGGGT CCGGGAGCGC 
TGGGTGCTAG AGGAGGTGGA AGAGCGGACC ACGTTAAGCG GACCTCGCTC TAAGCCCGCC 
TCCCCCAAAC TCTCTCCTGA CCCCCAGACT CCAACCGTAG CCCCAACAAA GAATGTACCC 
CGCAGTGCAG CTCCTCCAGT CCCACCTGCT TCCCTAATGG TCCCAGGTAC GAAGCCCGAA 
GCAGGGTCGA ACTCCCGGTG TCCTGCTGAA GGTGTGGCTT CAGCAGGCCT AACCAAAACG 
GGGGCACCCA GTCCTGCATC TTTAGGTCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.
Neuron100(6)1354-1368.e5(2018 12)
Tripathy R,Leca I,van Dijk T,Weiss J,van Bon BW,Sergaki MC,Gstrein T,Breuss M,Tian G,Bahi-Buisson N,Paciorkowski AR,Pagnamenta AT,Wenninger-Weinzierl A,Martinez-Reza MF,Landler L,Lise S,Taylor JC,Terrone G,Vitiello G,Del Giudice E,Brunetti-Pierri N,D'Amico A,Reymond A,Voisin N,Bernstein JA,Farrelly E,Kini U,Leonard TA,Valence S,Burglen L,Armstrong L,Hiatt SM,Cooper GM,Aldinger KA,Dobyns WB,Mirzaa G,Pierson TM,Baas F,Chelly J,Cowan NJ,Keays DA

Expression of the MAST family of serine/threonine kinases.
Brain research119512-9(2008 Feb)
Garland P,Quraishe S,French P,O'Connor V

Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions.
Neuroscience117(2)373-81(2003)
Yano R,Yap CC,Yamazaki Y,Muto Y,Kishida H,Okada D,Hashikawa T

Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.
Nature neuroscience2(7)611-7(1999 Jul)
Lumeng C,Phelps S,Crawford GE,Walden PD,Barald K,Chamberlain JS

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