Fancd2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fancd2
Entrez Gene ID	312641
Full Name	Fanconi anemia, complementation group D2
General protein information	Preferred Names Fanconi anemia, complementation group D2 Names Fanconi anemia group D2 protein homolog Fanconi anemia D2 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001719.1	NP_001001719.1	Fanconi anemia group D2 protein homolog

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os07g0154400	NP_001058915.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011769	XP_320741.4
Gallus gallus (chicken)	FANCD2	NP_001034350.1
Homo sapiens (human)	FANCD2	NP_001018125.1
Rattus norvegicus (Norway rat)	Fancd2	NP_001001719.1
Danio rerio (zebrafish)	fancd2	NP_958498.1
Xenopus tropicalis (tropical clawed frog)	fancd2	XP_002934277.2
Pan troglodytes (chimpanzee)	FANCD2	XP_003309761.1
Mus musculus (house mouse)	Fancd2	NP_001028416.2
Arabidopsis thaliana (thale cress)	AT4G14970	NP_193233.5
Drosophila melanogaster (fruit fly)	Fancd2	NP_996246.1
Bos taurus (cattle)	FANCD2	NP_001179358.1
Macaca mulatta (Rhesus monkey)	LOC716070	XP_002803125.1
Canis lupus familiaris (dog)	FANCD2	XP_005632233.1

Gene Ontology
Bibliography

Related articles in PubMed

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability.
Parplys AC, Zhao W, Sharma N, Groesser T, Liang F, Maranon DG, Leung SG, Grundt K, Dray E, Idate R, Østvold AC, Schild D, Sung P, Wiese C
Nucleic acids research43(20)9817-34(2015 Nov)

Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus.
Li X, Li L, Li J, Sipple J, Schick J, Mehta PA, Davies SM, Dasgupta B, Waclaw RR, Pang Q
Antioxidants & redox signaling21(12)1675-92(2014 Oct)

Deletion of Fanca or Fancd2 dysregulates Treg in mice.
Du W, Erden O, Wilson A, Sipple JM, Schick J, Mehta P, Myers KC, Steinbrecher KA, Davies SM, Pang Q
Blood123(12)1938-47(2014 Mar)

Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer.
Fagerholm R, Sprott K, Heikkinen T, Bartkova J, Heikkilä P, Aittomäki K, Bartek J, Weaver D, Blomqvist C, Nevanlinna H
Annals of oncology : official journal of the European Society for Medical Oncology24(11)2780-5(2013 Nov)

Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice.
Park E, Kim JM, Primack B, Weinstock DM, Moreau LA, Parmar K, D'Andrea AD
Molecular and cellular biology33(22)4360-70(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fancd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fancd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09694	NM_001001719.1 Latest version!	Rattus norvegicus FA complementation group D2 (Fancd2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fancd2 ( NM_001001719.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001001719.1 Rattus norvegicus FA complementation group D2 (Fancd2), mRNA.

Price & Availability↑

CloneID	ORa09694
Clone ID Related Accession (Same CDS sequence)	NM_001001719.1
Accession Version	NM_001001719.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	Fanconi anemia group D2 protein homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY621075.1. On Aug 30, 2004 this sequence version replaced XM_232273.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY621075.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMEA2689599 [ECO:0000350] ##Evidence-Data-END##

ATGGTCAAAA TGGTTTCCAA AAGAAGTCGG TTAGATTTTG AGGATAAAGA AACCCTGGCA 
GAAGATGCCT CCAAAATCAT GAAGCAACCC CTTTCCAAGT TGGCAAAGAA GTCTTGTGGT 
TCTCATGAAG TTGAAGAAAA TGGCAGTGTT TTTGTAAGGC TTCTTAAGGC GTCAGGACTC 
ACTCTGAAAA CTGGAGACAA CCAAAATCAG CTAGGTGTGG ATCAGATAAT CTTCCAAAGG 
AAGCTCTTTC AGGCCTTGAG GAAGCATCCT TCTTATCCCA AAGTAATAGA AGAATTTGTT 
AATGGCCTGG AGTCCTACAC TGAGGACATT GACAGTCTCA GGAACTGCCT GCTGTCTTGT 
GAGCGCCTGC AGGATGAGGA AGCCAGCATG GGCACATTTT ACTCCAAGAG TCTGATCAAG 
CTTCTTCTGG GGATTGACAT TTTGCAGCCT GCCATTATCA AAATGCTATT TGAAAAAGTG 
CCACAGTTTC TTTTTGAAAG CGAGAGCAGA GATGGGATCA GCATGCCCCG ACTCATCATC 
AGTCAGCTAA AGTGGCTGGA TAGAATCGTG GACAGCAAGG ACCTCACAAC CCAGATGATG 
CAGTTGATCA GTGTTGCTCC AGTGAATTTA CAACATGACT TCATCACTAG CCTTCCTGAG 
ATCCTAGGGG ATTCCCAGCA TGCTAATGTG GGGAAAGAGC TCAGTGAGCT GCTGGTGCAG 
AATACTTCAC TGACTGTTCC GATCTTGGAT GTCTTTTCCA GTCTCCGACT TGACCCAAAC 
TTCCTGTCTG AGATCCGCCA GTTGGTGATG GGCAAGCTGT CATCTGTCCG TCTAGAGGAC 
TTACCTGTGA TAGTAAAGTT CATTCTTCAT TCTGTGACAG ACAGCACTTC ACTAGAGGTG 
ATTGCTGAGC TGCGGGAGAA GTTGAACGTC CAGCATTTTA CCTTGCCGTC ACGAATTCAG 
GCTTCCCAAA GCAAGTTGAA AAGTAAAGGA TTAGCAAGCT CTTCAGGAAA TCAAGAAAAC 
AGTGATAAAG ACTGTATTGT TCTCCTCTTT GATGTAATAA AGTCAGCCAT TAGATACGAG 
AAAACCATTT CAGAAGCCTG GATCAAGGCA ATTGAACGCA TTCAGTCAGC GGCTGAACAT 
AAGGCTTTGG ACGTGGCAAT GTTGCTCATC ATCTATGGAA CCAGCACTCA GACAAAGAAG 
GGCGTTGAGA GGCTTCTGAG AAACAAGATT CAGTCAGACT GCATTCAAGA ACAGCTCCTT 
GACAGTACGT TCTCTACACA TTGCTTGGTT CTTAAGGATA TTTGCCCATC TATCCTTCTG 
CTGGCTCAGA CTTTGTTTCA CTCCCAAGAC CAGAGGATAA TTTTGTTTGG CAGTCTTCTA 
TGCAAATATG CCTTTAAGTT TTTTGATACC TACTGCCAGC AGGAAGTGGT TGGTGCTTTA 
GTAACCCATG TATGCAGTGG GAATGAGGCT GAAGTTGATG CTGCATTAGA TGTCCTCCTG 
GAGCTGATTG TGCTAAACGC CTCTGCCATG AGGCTCAACG CTGCTTTTAT TAAGGGCATT 
TTAGATTATT TGGAAAATAT GTCCCCTCAA CAAATACGAA AAATCTTCTG TATTCTCAGC 
ACTCTAGCAT TTAGCCAACA GCCCGGAACC AGCAACCATA TCCAGGATGA CATGCACCTG 
GTGATCCGGA AGCAGCTCTC TAGCACTGTG TTCAAGTACA AACTCATTGG GATCATCGGT 
GCAGTCACCA TGGCCGGCAT CATGGCAGAA GACAGAACTA TGCCATCTAA TTCAACCCAG 
AGGAGCGCCA GTGTGAGCAG TGAACAGCAC ACACAGGTGA CTTCTTTGTT ACAACTGGTT 
CATTCCTGCA CCGAACACTC TCCTTGGGCC TCTTCTCTTT ATTATGATGA ATTTGCCAAC 
CTCATCCAAG AAAGAAAGTT GGCTCCAAAA ACCTTGGAAT GGGTTGCTCA GACGATCTTT 
AATGATTTCC AAGATGCCTT TGTGGTGGAC TTCTGTGCTG TTCCAGAAGG TGACTTTCCA 
TTTCCTGTGA AAGCGCTCTA TGGACTGGAA GAATGCAACA CTCAAGATGG CATTGTCATC 
AACCTCCTGC CACTGTTCTT TCAGGAATTT GCAAAAGATG TCAGTCAAGT GACTTCACAA 
GAATCAAGCC AGAAATCAAT GTCTCCTTTG TGCCTGGCTT CCCATTTCCG GCTGCTGAGA 
CTTTGCGTGG CAAGACAACA TAACGGAAAC TTGGATGAGA TCGATGCTCT CTTAGATTGT 
CCCCTGTTCC TCCCTGACCT GGAACCTGGA GAGAAACTGG AGTCCATGTC TGCTAAAGAC 
CGTTCACTCA TGTGTTCACT CACATTCTTA ACTTTCAACT GGTTCAGAGA GGTTGTGAAT 
GCCTTCTGCC AACAAACTTC TCCTGAGATG AAGGGCAAGG TTCTTAGTCG GCTAAAGGAC 
CTTGTGGAGC TTCAGGAGAT CCTAGAGAAG TACTTGGCAG TCATCCCAGA CTATGTCCCA 
CCTTTCACAA GCGTTGACTT GGATACTTTA GATGTGATAC CTAGGAGCAA TTCTGCTGTT 
GCTGCAAAAA GCAGACACAA GGGAAAGACC GGGGGAAAGA AACAGAAAGC TGATAGCAGC 
ACAGCATCCT GCACGGACAC ACTTCTCACA GAAGACACTT CAGAATGTGA CGTGGCACCG 
TCTGGGAAAA GCCAAGTAGA CAAGGAGTCT ACAGGGAAGG AAGGAAAGAC GTTTGTGTCA 
CTGCAGAATT ACCGTGCTTT CTTCCGAGAG CTGGACATTG AAGTCTTCTC TATTCTGCAT 
TCTGGACTTG TGACCAAGTT CATCTTAGAC ACTGAAATGC ACACTGAAGC TACAGAAGTT 
GTCCAGCTGG GGCCTGCTGA GCTGCTTTTC TTGCTGGAAG ATCTTTCCCA GAAGCTAGAG 
AATAGACTCA CTCCTTCCTT TACCAAGAGA GTCTGTTTCT TCAAGAATAA AGGAAGCCGG 
AATATTGGAT TCTCACATCT TCATCAGAGA TCTGTCCAGG ACATTGTGCA TTGTGTTGTT 
CAGCTGCTAA CCCCCATGTG TAACCATCTG GAGAACATTC ACAACTTCTT CCAGTGCTTA 
GGTGCTGAGA ATCTCAGTGT AAATGACAAG GCCAGAGTGA CAGCTCAGGA GCACTACACC 
ATGTCCTCCT GCTACCAGAA GCTGCTGCAG GTCTTCCATG CACTCTTGGC TTGGAAAGGA 
TTTACTCACC AATCAAACCA CCGCCTCCTG CGCTCAGCCC TTGAGGTCCT TGCGAGCCGA 
CTGAAGCAGA CGGAAGAGGG GCAGCCCTTG GAGGAACTGC TCAGCCAGAG CTTCAGTTAC 
TTGCAGAATT TGCAGCACAG CATTCCCAGT TTCCAGTGTG GTCTTTATCT CCTCAGACTT 
CTGATGGCCC TTCTGGAGAA GTCTGCAGTA CCTACCCAGA AGAAAGAAAA ACTTGCCTCT 
CTGGCCAAAC AGCTGCTTTG TCGAGCATGG CCTCATGGGG ACAAAGAGAA GAACCCCACT 
TTTAATGACC ACCTCCATGA CTTGCTTTGC ATCTACTTGG AGCACACAGA CAATGTTCTG 
AAGGCCATAG AGGAGATCAC TGGTGTTGGT GTCCCAGAAC TGGTCAATGC TCCGAAAGAT 
GCCTCCTCTT CTACATTCCC CACGTTGACC AGGCACACCT TTGTCATCTT CTTCCGTGTG 
ATGATGGCTG AACTTGAGAA GACGGTGAAA GGTCTTCAGG CTGGCACAGC TACAGATTCC 
CAGCAGGTTC ACGAAGAGAA GCTTCTCTAT TGGAACATGG CTGTCCGAGA CTTCAGCATC 
CTTATCAATC TGATGAAGGT ATTTGACAGT TATCCTGTTC TGCATGTGTG TTTAAAGTAT 
GGCCGTCGCT TTGTGGAGGC ATTTCTGAAG CAGTGCATGC CGCTCCTCGA CTTCAGCTTT 
AGAAAGCATC GGGATGATGT TCTGAGCTTG CTGCAAACCC TTCAGTTGAA CACAAGGCTA 
CTTCATCACC TTTGTGGACA CTCCAAGATT CACCAGGACA CAAGACTCAC CAAACATGTG 
CCTTTACTCA AAAAGTCACT GGAGCTGTTA GTTTGCAGAG TCAAAGCCAT GCTTGTCCTC 
AACAATTGTA GAGAGGCTTT CTGGTTGGGT ACTCTCAAAA ACCGAGACTT ACAGGGTGAA 
GAAATTATTT CCCAGCATCC CTCCTCCCCA GAAAACACTT CAGAGGACAG TGAGGATGGC 
ATGACATCCT ATGTCTCCAG GAACAGAGCA ATAGAGGATG GGGAAGATGA AGCAAATGAT 
GGACAGGACA GGGACAGTGA TGAGAGTGAC GACAGCTCCA GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001719.1
CDS	1..4365
Translation	MVKMVSKRSRLDFEDKETLAEDASKIMKQPLSKLAKKSCGSHEVEENGSVFVRLLKASGLTLKTGDNQNQLGVDQIIFQRKLFQALRKHPSYPKVIEEFVNGLESYTEDIDSLRNCLLSCERLQDEEASMGTFYSKSLIKLLLGIDILQPAIIKMLFEKVPQFLFESESRDGISMPRLIISQLKWLDRIVDSKDLTTQMMQLISVAPVNLQHDFITSLPEILGDSQHANVGKELSELLVQNTSLTVPILDVFSSLRLDPNFLSEIRQLVMGKLSSVRLEDLPVIVKFILHSVTDSTSLEVIAELREKLNVQHFTLPSRIQASQSKLKSKGLASSSGNQENSDKDCIVLLFDVIKSAIRYEKTISEAWIKAIERIQSAAEHKALDVAMLLIIYGTSTQTKKGVERLLRNKIQSDCIQEQLLDSTFSTHCLVLKDICPSILLLAQTLFHSQDQRIILFGSLLCKYAFKFFDTYCQQEVVGALVTHVCSGNEAEVDAALDVLLELIVLNASAMRLNAAFIKGILDYLENMSPQQIRKIFCILSTLAFSQQPGTSNHIQDDMHLVIRKQLSSTVFKYKLIGIIGAVTMAGIMAEDRTMPSNSTQRSASVSSEQHTQVTSLLQLVHSCTEHSPWASSLYYDEFANLIQERKLAPKTLEWVAQTIFNDFQDAFVVDFCAVPEGDFPFPVKALYGLEECNTQDGIVINLLPLFFQEFAKDVSQVTSQESSQKSMSPLCLASHFRLLRLCVARQHNGNLDEIDALLDCPLFLPDLEPGEKLESMSAKDRSLMCSLTFLTFNWFREVVNAFCQQTSPEMKGKVLSRLKDLVELQEILEKYLAVIPDYVPPFTSVDLDTLDVIPRSNSAVAAKSRHKGKTGGKKQKADSSTASCTDTLLTEDTSECDVAPSGKSQVDKESTGKEGKTFVSLQNYRAFFRELDIEVFSILHSGLVTKFILDTEMHTEATEVVQLGPAELLFLLEDLSQKLENRLTPSFTKRVCFFKNKGSRNIGFSHLHQRSVQDIVHCVVQLLTPMCNHLENIHNFFQCLGAENLSVNDKARVTAQEHYTMSSCYQKLLQVFHALLAWKGFTHQSNHRLLRSALEVLASRLKQTEEGQPLEELLSQSFSYLQNLQHSIPSFQCGLYLLRLLMALLEKSAVPTQKKEKLASLAKQLLCRAWPHGDKEKNPTFNDHLHDLLCIYLEHTDNVLKAIEEITGVGVPELVNAPKDASSSTFPTLTRHTFVIFFRVMMAELEKTVKGLQAGTATDSQQVHEEKLLYWNMAVRDFSILINLMKVFDSYPVLHVCLKYGRRFVEAFLKQCMPLLDFSFRKHRDDVLSLLQTLQLNTRLLHHLCGHSKIHQDTRLTKHVPLLKKSLELLVCRVKAMLVLNNCREAFWLGTLKNRDLQGEEIISQHPSSPENTSEDSEDGMTSYVSRNRAIEDGEDEANDGQDRDSDESDDSSS

Target ORF information:

RefSeq Version	NM_001001719.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FA complementation group D2 (Fancd2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001719.1

ORF Insert Sequence:

ATGGTCAAAA TGGTTTCCAA AAGAAGTCGG TTAGATTTTG AGGATAAAGA AACCCTGGCA 
GAAGATGCCT CCAAAATCAT GAAGCAACCC CTTTCCAAGT TGGCAAAGAA GTCTTGTGGT 
TCTCATGAAG TTGAAGAAAA TGGCAGTGTT TTTGTAAGGC TTCTTAAGGC GTCAGGACTC 
ACTCTGAAAA CTGGAGACAA CCAAAATCAG CTAGGTGTGG ATCAGATAAT CTTCCAAAGG 
AAGCTCTTTC AGGCCTTGAG GAAGCATCCT TCTTATCCCA AAGTAATAGA AGAATTTGTT 
AATGGCCTGG AGTCCTACAC TGAGGACATT GACAGTCTCA GGAACTGCCT GCTGTCTTGT 
GAGCGCCTGC AGGATGAGGA AGCCAGCATG GGCACATTTT ACTCCAAGAG TCTGATCAAG 
CTTCTTCTGG GGATTGACAT TTTGCAGCCT GCCATTATCA AAATGCTATT TGAAAAAGTG 
CCACAGTTTC TTTTTGAAAG CGAGAGCAGA GATGGGATCA GCATGCCCCG ACTCATCATC 
AGTCAGCTAA AGTGGCTGGA TAGAATCGTG GACAGCAAGG ACCTCACAAC CCAGATGATG 
CAGTTGATCA GTGTTGCTCC AGTGAATTTA CAACATGACT TCATCACTAG CCTTCCTGAG 
ATCCTAGGGG ATTCCCAGCA TGCTAATGTG GGGAAAGAGC TCAGTGAGCT GCTGGTGCAG 
AATACTTCAC TGACTGTTCC GATCTTGGAT GTCTTTTCCA GTCTCCGACT TGACCCAAAC 
TTCCTGTCTG AGATCCGCCA GTTGGTGATG GGCAAGCTGT CATCTGTCCG TCTAGAGGAC 
TTACCTGTGA TAGTAAAGTT CATTCTTCAT TCTGTGACAG ACAGCACTTC ACTAGAGGTG 
ATTGCTGAGC TGCGGGAGAA GTTGAACGTC CAGCATTTTA CCTTGCCGTC ACGAATTCAG 
GCTTCCCAAA GCAAGTTGAA AAGTAAAGGA TTAGCAAGCT CTTCAGGAAA TCAAGAAAAC 
AGTGATAAAG ACTGTATTGT TCTCCTCTTT GATGTAATAA AGTCAGCCAT TAGATACGAG 
AAAACCATTT CAGAAGCCTG GATCAAGGCA ATTGAACGCA TTCAGTCAGC GGCTGAACAT 
AAGGCTTTGG ACGTGGCAAT GTTGCTCATC ATCTATGGAA CCAGCACTCA GACAAAGAAG 
GGCGTTGAGA GGCTTCTGAG AAACAAGATT CAGTCAGACT GCATTCAAGA ACAGCTCCTT 
GACAGTACGT TCTCTACACA TTGCTTGGTT CTTAAGGATA TTTGCCCATC TATCCTTCTG 
CTGGCTCAGA CTTTGTTTCA CTCCCAAGAC CAGAGGATAA TTTTGTTTGG CAGTCTTCTA 
TGCAAATATG CCTTTAAGTT TTTTGATACC TACTGCCAGC AGGAAGTGGT TGGTGCTTTA 
GTAACCCATG TATGCAGTGG GAATGAGGCT GAAGTTGATG CTGCATTAGA TGTCCTCCTG 
GAGCTGATTG TGCTAAACGC CTCTGCCATG AGGCTCAACG CTGCTTTTAT TAAGGGCATT 
TTAGATTATT TGGAAAATAT GTCCCCTCAA CAAATACGAA AAATCTTCTG TATTCTCAGC 
ACTCTAGCAT TTAGCCAACA GCCCGGAACC AGCAACCATA TCCAGGATGA CATGCACCTG 
GTGATCCGGA AGCAGCTCTC TAGCACTGTG TTCAAGTACA AACTCATTGG GATCATCGGT 
GCAGTCACCA TGGCCGGCAT CATGGCAGAA GACAGAACTA TGCCATCTAA TTCAACCCAG 
AGGAGCGCCA GTGTGAGCAG TGAACAGCAC ACACAGGTGA CTTCTTTGTT ACAACTGGTT 
CATTCCTGCA CCGAACACTC TCCTTGGGCC TCTTCTCTTT ATTATGATGA ATTTGCCAAC 
CTCATCCAAG AAAGAAAGTT GGCTCCAAAA ACCTTGGAAT GGGTTGCTCA GACGATCTTT 
AATGATTTCC AAGATGCCTT TGTGGTGGAC TTCTGTGCTG TTCCAGAAGG TGACTTTCCA 
TTTCCTGTGA AAGCGCTCTA TGGACTGGAA GAATGCAACA CTCAAGATGG CATTGTCATC 
AACCTCCTGC CACTGTTCTT TCAGGAATTT GCAAAAGATG TCAGTCAAGT GACTTCACAA 
GAATCAAGCC AGAAATCAAT GTCTCCTTTG TGCCTGGCTT CCCATTTCCG GCTGCTGAGA 
CTTTGCGTGG CAAGACAACA TAACGGAAAC TTGGATGAGA TCGATGCTCT CTTAGATTGT 
CCCCTGTTCC TCCCTGACCT GGAACCTGGA GAGAAACTGG AGTCCATGTC TGCTAAAGAC 
CGTTCACTCA TGTGTTCACT CACATTCTTA ACTTTCAACT GGTTCAGAGA GGTTGTGAAT 
GCCTTCTGCC AACAAACTTC TCCTGAGATG AAGGGCAAGG TTCTTAGTCG GCTAAAGGAC 
CTTGTGGAGC TTCAGGAGAT CCTAGAGAAG TACTTGGCAG TCATCCCAGA CTATGTCCCA 
CCTTTCACAA GCGTTGACTT GGATACTTTA GATGTGATAC CTAGGAGCAA TTCTGCTGTT 
GCTGCAAAAA GCAGACACAA GGGAAAGACC GGGGGAAAGA AACAGAAAGC TGATAGCAGC 
ACAGCATCCT GCACGGACAC ACTTCTCACA GAAGACACTT CAGAATGTGA CGTGGCACCG 
TCTGGGAAAA GCCAAGTAGA CAAGGAGTCT ACAGGGAAGG AAGGAAAGAC GTTTGTGTCA 
CTGCAGAATT ACCGTGCTTT CTTCCGAGAG CTGGACATTG AAGTCTTCTC TATTCTGCAT 
TCTGGACTTG TGACCAAGTT CATCTTAGAC ACTGAAATGC ACACTGAAGC TACAGAAGTT 
GTCCAGCTGG GGCCTGCTGA GCTGCTTTTC TTGCTGGAAG ATCTTTCCCA GAAGCTAGAG 
AATAGACTCA CTCCTTCCTT TACCAAGAGA GTCTGTTTCT TCAAGAATAA AGGAAGCCGG 
AATATTGGAT TCTCACATCT TCATCAGAGA TCTGTCCAGG ACATTGTGCA TTGTGTTGTT 
CAGCTGCTAA CCCCCATGTG TAACCATCTG GAGAACATTC ACAACTTCTT CCAGTGCTTA 
GGTGCTGAGA ATCTCAGTGT AAATGACAAG GCCAGAGTGA CAGCTCAGGA GCACTACACC 
ATGTCCTCCT GCTACCAGAA GCTGCTGCAG GTCTTCCATG CACTCTTGGC TTGGAAAGGA 
TTTACTCACC AATCAAACCA CCGCCTCCTG CGCTCAGCCC TTGAGGTCCT TGCGAGCCGA 
CTGAAGCAGA CGGAAGAGGG GCAGCCCTTG GAGGAACTGC TCAGCCAGAG CTTCAGTTAC 
TTGCAGAATT TGCAGCACAG CATTCCCAGT TTCCAGTGTG GTCTTTATCT CCTCAGACTT 
CTGATGGCCC TTCTGGAGAA GTCTGCAGTA CCTACCCAGA AGAAAGAAAA ACTTGCCTCT 
CTGGCCAAAC AGCTGCTTTG TCGAGCATGG CCTCATGGGG ACAAAGAGAA GAACCCCACT 
TTTAATGACC ACCTCCATGA CTTGCTTTGC ATCTACTTGG AGCACACAGA CAATGTTCTG 
AAGGCCATAG AGGAGATCAC TGGTGTTGGT GTCCCAGAAC TGGTCAATGC TCCGAAAGAT 
GCCTCCTCTT CTACATTCCC CACGTTGACC AGGCACACCT TTGTCATCTT CTTCCGTGTG 
ATGATGGCTG AACTTGAGAA GACGGTGAAA GGTCTTCAGG CTGGCACAGC TACAGATTCC 
CAGCAGGTTC ACGAAGAGAA GCTTCTCTAT TGGAACATGG CTGTCCGAGA CTTCAGCATC 
CTTATCAATC TGATGAAGGT ATTTGACAGT TATCCTGTTC TGCATGTGTG TTTAAAGTAT 
GGCCGTCGCT TTGTGGAGGC ATTTCTGAAG CAGTGCATGC CGCTCCTCGA CTTCAGCTTT 
AGAAAGCATC GGGATGATGT TCTGAGCTTG CTGCAAACCC TTCAGTTGAA CACAAGGCTA 
CTTCATCACC TTTGTGGACA CTCCAAGATT CACCAGGACA CAAGACTCAC CAAACATGTG 
CCTTTACTCA AAAAGTCACT GGAGCTGTTA GTTTGCAGAG TCAAAGCCAT GCTTGTCCTC 
AACAATTGTA GAGAGGCTTT CTGGTTGGGT ACTCTCAAAA ACCGAGACTT ACAGGGTGAA 
GAAATTATTT CCCAGCATCC CTCCTCCCCA GAAAACACTT CAGAGGACAG TGAGGATGGC 
ATGACATCCT ATGTCTCCAG GAACAGAGCA ATAGAGGATG GGGAAGATGA AGCAAATGAT 
GGACAGGACA GGGACAGTGA TGAGAGTGAC GACAGCTCCA GTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability.
Nucleic acids research43(20)9817-34(2015 Nov)
Parplys AC,Zhao W,Sharma N,Groesser T,Liang F,Maranon DG,Leung SG,Grundt K,Dray E,Idate R,Østvold AC,Schild D,Sung P,Wiese C

Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus.
Antioxidants & redox signaling21(12)1675-92(2014 Oct)
Li X,Li L,Li J,Sipple J,Schick J,Mehta PA,Davies SM,Dasgupta B,Waclaw RR,Pang Q

Deletion of Fanca or Fancd2 dysregulates Treg in mice.
Blood123(12)1938-47(2014 Mar)
Du W,Erden O,Wilson A,Sipple JM,Schick J,Mehta P,Myers KC,Steinbrecher KA,Davies SM,Pang Q

Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology24(11)2780-5(2013 Nov)
Fagerholm R,Sprott K,Heikkinen T,Bartkova J,Heikkilä P,Aittomäki K,Bartek J,Weaver D,Blomqvist C,Nevanlinna H

Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice.
Molecular and cellular biology33(22)4360-70(2013 Nov)
Park E,Kim JM,Primack B,Weinstock DM,Moreau LA,Parmar K,D'Andrea AD

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Fancd2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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