Cyss cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cyss
Entrez Gene ID	296234
Full Name	cystatin S
Synonyms	Cst4
General protein information	Preferred Names cystatin S Names cystatin-S LM protein cystatin-1 protein LM
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41
Summary	cysteine proteinase inhibitor; may be regulated by cAMP mediated signaling and by estrogen [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_198685.1	NP_941958.1	cystatin-S precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	LOC689220	XP_003749635.1
Rattus norvegicus (Norway rat)	Cyss	NP_941958.1
Rattus norvegicus (Norway rat)	LOC296235	NP_001032427.1
Rattus norvegicus (Norway rat)	LOC689168	XP_006235248.1

Gene Ontology
Bibliography

Related articles in PubMed

Changes in submaxillary gland gene expression in F344 rats by multiple dosing of theophylline.
Kajikawa S, Kigami D, Nakayama H, Doi K
Experimental animals55(2)143-6(2006 Apr)

Impaired induction of cystatin S gene expression by isoproterenol in the submandibular gland of hypophysectomized rats.
Iseki S, Kim JG, Kudo Y, Naito Y, Hipkaeo W
Archives of oral biology50(7)653-60(2005 Jul)

Sympathetic and parasympathetic regulation of cystatin S gene expression.
Shaw PA, Yu WH
Life sciences70(3)301-13(2001 Dec)

Postnatal changes of gene expression for tissue inhibitors of metalloproteinase-1 and -2 and cystatins S and C, in rat submandibular gland demonstrated by quantitative reverse transcription-polymerase chain reaction.
Nishiura T, Abe K
Archives of oral biology44(1)15-26(1999 Jan)

Abnormally high levels of cystatin S in submandibular glands, saliva, and gingiva of plaque-resistant rats.
Abe K, Okina A, Yano T, Gao C, Ohmori H, Ishibashi K, Nishiura T, Letić-Gavrilović A
Journal of dental research77(11)1913-9(1998 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cyss gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cyss cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42520	NM_198685.1 Latest version!	Rattus norvegicus cystatin S (Cyss), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cyss ( NM_198685.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_941958.1 Rattus norvegicus cystatin S (Cyss), mRNA.

Price & Availability↑

CloneID	ORa42520
Clone ID Related Accession (Same CDS sequence)	NM_198685.1
Accession Version	NM_198685.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 426bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	cystatin-S precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M75281.1. On Dec 17, 2003 this sequence version replaced XM_215879.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J04206.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCCTACC TGCTCCATGC TCAACTATTT CTACTGACTA CCTTTATATT AGTTTTGAAC 
ATGAGACTTT GTCCTGTTCT AGGTCACTTT CTGGGTGGCA TAGAGAAGTC TAGCATGGAG 
GAGGAAGGAG CCTCAGAAGC ATTGAACTAT GCTGTCAATG AGTATAATGA AAAGAACAGT 
GACTTGTACC TGAGCCGTGT GGTGGAAGTG AAGGATGTCC AAAAGCAGGT GGTGGCTGGA 
ACCAAATTTT TCTTTGATGT GATTCTAGGC AAAACAATAT GTTTGAAGAC ACAGGGTGAC 
TTGACCAACT GTCCCTTAAA TGAAGAGGCT GATCAGCAGG AGCATGAATT CTGCTCTTTC 
GTGGTTCATG ATATCCCATG GGAGAATTAT ATTGTCTTGC TGAGCTCCAG CTGTCATAGT 
ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_941958.1
CDS	1..426
Translation	MAYLLHAQLFLLTTFILVLNMRLCPVLGHFLGGIEKSSMEEEGASEALNYAVNEYNEKNSDLYLSRVVEVKDVQKQVVAGTKFFFDVILGKTICLKTQGDLTNCPLNEEADQQEHEFCSFVVHDIPWENYIVLLSSSCHSI

Target ORF information:

RefSeq Version	NM_198685.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cystatin S (Cyss), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198685.1

ORF Insert Sequence:

ATGGCCTACC TGCTCCATGC TCAACTATTT CTACTGACTA CCTTTATATT AGTTTTGAAC 
ATGAGACTTT GTCCTGTTCT AGGTCACTTT CTGGGTGGCA TAGAGAAGTC TAGCATGGAG 
GAGGAAGGAG CCTCAGAAGC ATTGAACTAT GCTGTCAATG AGTATAATGA AAAGAACAGT 
GACTTGTACC TGAGCCGTGT GGTGGAAGTG AAGGATGTCC AAAAGCAGGT GGTGGCTGGA 
ACCAAATTTT TCTTTGATGT GATTCTAGGC AAAACAATAT GTTTGAAGAC ACAGGGTGAC 
TTGACCAACT GTCCCTTAAA TGAAGAGGCT GATCAGCAGG AGCATGAATT CTGCTCTTTC 
GTGGTTCATG ATATCCCATG GGAGAATTAT ATTGTCTTGC TGAGCTCCAG CTGTCATAGT 
ATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Changes in submaxillary gland gene expression in F344 rats by multiple dosing of theophylline.
Experimental animals55(2)143-6(2006 Apr)
Kajikawa S,Kigami D,Nakayama H,Doi K

Impaired induction of cystatin S gene expression by isoproterenol in the submandibular gland of hypophysectomized rats.
Archives of oral biology50(7)653-60(2005 Jul)
Iseki S,Kim JG,Kudo Y,Naito Y,Hipkaeo W

Sympathetic and parasympathetic regulation of cystatin S gene expression.
Life sciences70(3)301-13(2001 Dec)
Shaw PA,Yu WH

Postnatal changes of gene expression for tissue inhibitors of metalloproteinase-1 and -2 and cystatins S and C, in rat submandibular gland demonstrated by quantitative reverse transcription-polymerase chain reaction.
Archives of oral biology44(1)15-26(1999 Jan)
Nishiura T,Abe K

Abnormally high levels of cystatin S in submandibular glands, saliva, and gingiva of plaque-resistant rats.
Journal of dental research77(11)1913-9(1998 Nov)
Abe K,Okina A,Yano T,Gao C,Ohmori H,Ishibashi K,Nishiura T,Letić-Gavrilović A