Enc1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Enc1
Entrez Gene ID	294674
Full Name	ectodermal-neural cortex 1
Synonyms	Nrpb
General protein information	Preferred Names ectodermal-neural cortex 1 Names ectoderm-neural cortex protein 1 nuclear restrict protein in brain
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q12
Summary	mouse homolog binds actin and may play a role in nervous system induction and development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003401.1	NP_001003401.1	ectoderm-neural cortex protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENC1	NP_003624.1
Rattus norvegicus (Norway rat)	Enc1	NP_001003401.1
Pan troglodytes (chimpanzee)	ENC1	XP_003310724.1
Canis lupus familiaris (dog)	ENC1	XP_544373.4
Mus musculus (house mouse)	Enc1	NP_031956.3
Bos taurus (cattle)	ENC1	NP_001071535.1
Macaca mulatta (Rhesus monkey)	ENC1	XP_001103216.1
Gallus gallus (chicken)	ENC1	XP_004937417.1
Danio rerio (zebrafish)	LOC559101	XP_687500.2
Xenopus tropicalis (tropical clawed frog)	enc1	XP_002934870.1

Gene Ontology
Bibliography

Related articles in PubMed

Inhibition of Ectodermal-Neural Cortex 1 Protects Neural Cells from Apoptosis Induced by Hypoxia and Hypoglycemia.
Lei H, Li J, Zhao Z, Liu L
Journal of molecular neuroscience : MN59(1)126-34(2016 May)

Overexpression of Nrp/b (nuclear restrict protein in brain) suppresses the malignant phenotype in the C6/ST1 glioma cell line.
Degaki TL, Demasi MA, Sogayar MC
The Journal of steroid biochemistry and molecular biology117(4-5)107-16(2009 Nov)

Expression of ectodermal neural cortex 1 and its association with actin during the ovulatory process in the rat.
Kim SG, Jang SJ, Soh J, Lee K, Park JK, Chang WK, Park EW, Chun SY
Endocrinology150(8)3800-6(2009 Aug)

Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level.
Wang XJ, Zhang DD
PloS one4(5)e5492(2009)

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M
The Journal of biological chemistry280(34)30091-9(2005 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Enc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Enc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09843	NM_001003401.1 Latest version!	Rattus norvegicus ectodermal-neural cortex 1 (Enc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Enc1 ( NM_001003401.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001003401.1 Rattus norvegicus ectodermal-neural cortex 1 (Enc1), mRNA.

Price & Availability↑

CloneID	ORa09843
Clone ID Related Accession (Same CDS sequence)	NM_001003401.1
Accession Version	NM_001003401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527264000000
Organism	Rattus norvegicus(Norway rat)
Product	ectoderm-neural cortex protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY669396.1. On Aug 30, 2004 this sequence version replaced XM_215453.2. ##Evidence-Data-START## Transcript exon combination :: AY669396.1, DQ282125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCCGTCA GCGTGCATGA GAACCGCAAG TCCAGGGCCA GCAGCGGCTC CATCAACATC 
TACCTGTTTC ATAAGTCTTC CTATGCCGAC AGTGTTCTCA CTCACTTGAA CCTTCTGCGT 
CAGCAGAGGC TCTTTACAGA CGTCCTCCTT CATGCGGGAA ACAGGACCTT CCCTTGCCAC 
CGGGCAGTGT TGGCTGCCTG CAGCCGCTAC TTCGAAGCCA TGTTCAGTGG TGGCCTGAAA 
GAGAGCCAGG ACAGTGAGGT GAACTTCGAC AATTCCATCC ACCCAGAAGT CTTAGAGCTG 
CTTCTGGACT ACGCATACTC CTCCCGGGTC ATCATCAATG AAGAAAATGC TGAGTCCCTC 
CTGGAGGCTG GTGACATGCT GGAGTTTCAG GACATCAGGG ATGCATGTGC AGAATTCCTG 
GAGAAGAACC TGCATCCCAC CAACTGCTTA GGGATGCTGC TGCTGTCTGA CGCCCACCAG 
TGCACCAAGC TGTACGAACT CTCCTGGAGA ATGTGTCTGA GCAACTTCCA AACCATCCGG 
AAGAATGAAG ATTTTCTCCA GTTGCCCCAG GACATGGTGG TGCAGCTCCT GTCCAGCGAA 
GAACTGGAGA CAGAAGACGA AAGGCTGGTG TATGAGTCTG CAATGAACTG GATTAGCTAT 
GACCTGAAGA AACGCTACTG TTACCTCCCA GAACTGTTGC AGACAGTGAG GCTGGCCCTT 
CTTCCTGCCA TCTATCTCAT GGAGAACGTG GCAATGGAAG AACTCATCAC CAAGCAGAGA 
AAGAGTAAGG AGATTGTGGA AGAGGCCATC CGGTGCAAAC TAAAAATCTT ACAGAATGAC 
GGCGTGGTCA CCAGTCTCTG TGCTCGCCCT CGGAAAACTG GCCACGCCCT GTTCCTCCTG 
GGAGGGCAGA CTTTCATGTG TGACAAACTG TACTTGGTAG ACCAGAAGGC TAAAGAAATC 
ATTCCCAAGG CTGACATTCC CAGCCCGAGG AAAGAGTTCA GTGCGTGTGC GATTGGCTGC 
AAAGTGTATA TTACTGGGGG GCGGGGATCA GAGAACGGAG TCTCAAAAGA TGTCTGGGTT 
TATGATACCC TGCATGAGGA ATGGTCCAAG GCTGCCCCCA TGCTGGTGGC CAGGTTTGGC 
CATGGATCAG CCGAACTGAA GCACTGCCTG TATGTGGTCG GTGGGCACAC AGCTGCAACT 
GGCTGCCTCC CAGCCTCTCC TTCAGTCTCT CTAAAGCAAG TAGAACAATA TGACCCCACA 
ACCAACAAAT GGACCATGGT AGCCCCACTC CGAGAAGGTG TCAGCAATGC TGCTGTAGTG 
AGCGCCAAGC TCAAGCTGTT CGCTTTCGGA GGTACCAGCG TAAGCCACGA CAAGCTTCCT 
AAGGTTCAGT GTTATGACCA GTGTGAAAAC AGATGGACAG TTCCAGCCAC CTGTCCCCAG 
CCCTGGCGTT ACACAGCCGC AGCTGTGCTG GGGAACCAGA TTTTTATCAT GGGTGGGGAT 
ACAGAATTCT CAGCCTGCTC TGCTTACAAG TTCAACAGTG AAACTTACCA GTGGACCAAG 
GTAGGAGACG TGACAGCCAA GCGCATGAGC TGCCATGCCG TGGCCTCCGG GAACAAGCTT 
TACGTGGTTG GAGGATACTT CGGCATTCAG CGCTGCAAGA CGTTGGACTG TTACGATCCG 
ACTTTAGATG TGTGGAACAG CATAACCACG GTTCCCTACT CTCTGATCCC TACCGCGTTC 
GTCAGCACCT GGAAACACCT GCCTTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003401.1
CDS	329..2098
Translation	MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS

Target ORF information:

RefSeq Version	NM_001003401.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ectodermal-neural cortex 1 (Enc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003401.1

ORF Insert Sequence:

ATGTCCGTCA GCGTGCATGA GAACCGCAAG TCCAGGGCCA GCAGCGGCTC CATCAACATC 
TACCTGTTTC ATAAGTCTTC CTATGCCGAC AGTGTTCTCA CTCACTTGAA CCTTCTGCGT 
CAGCAGAGGC TCTTTACAGA CGTCCTCCTT CATGCGGGAA ACAGGACCTT CCCTTGCCAC 
CGGGCAGTGT TGGCTGCCTG CAGCCGCTAC TTCGAAGCCA TGTTCAGTGG TGGCCTGAAA 
GAGAGCCAGG ACAGTGAGGT GAACTTCGAC AATTCCATCC ACCCAGAAGT CTTAGAGCTG 
CTTCTGGACT ACGCATACTC CTCCCGGGTC ATCATCAATG AAGAAAATGC TGAGTCCCTC 
CTGGAGGCTG GTGACATGCT GGAGTTTCAG GACATCAGGG ATGCATGTGC AGAATTCCTG 
GAGAAGAACC TGCATCCCAC CAACTGCTTA GGGATGCTGC TGCTGTCTGA CGCCCACCAG 
TGCACCAAGC TGTACGAACT CTCCTGGAGA ATGTGTCTGA GCAACTTCCA AACCATCCGG 
AAGAATGAAG ATTTTCTCCA GTTGCCCCAG GACATGGTGG TGCAGCTCCT GTCCAGCGAA 
GAACTGGAGA CAGAAGACGA AAGGCTGGTG TATGAGTCTG CAATGAACTG GATTAGCTAT 
GACCTGAAGA AACGCTACTG TTACCTCCCA GAACTGTTGC AGACAGTGAG GCTGGCCCTT 
CTTCCTGCCA TCTATCTCAT GGAGAACGTG GCAATGGAAG AACTCATCAC CAAGCAGAGA 
AAGAGTAAGG AGATTGTGGA AGAGGCCATC CGGTGCAAAC TAAAAATCTT ACAGAATGAC 
GGCGTGGTCA CCAGTCTCTG TGCTCGCCCT CGGAAAACTG GCCACGCCCT GTTCCTCCTG 
GGAGGGCAGA CTTTCATGTG TGACAAACTG TACTTGGTAG ACCAGAAGGC TAAAGAAATC 
ATTCCCAAGG CTGACATTCC CAGCCCGAGG AAAGAGTTCA GTGCGTGTGC GATTGGCTGC 
AAAGTGTATA TTACTGGGGG GCGGGGATCA GAGAACGGAG TCTCAAAAGA TGTCTGGGTT 
TATGATACCC TGCATGAGGA ATGGTCCAAG GCTGCCCCCA TGCTGGTGGC CAGGTTTGGC 
CATGGATCAG CCGAACTGAA GCACTGCCTG TATGTGGTCG GTGGGCACAC AGCTGCAACT 
GGCTGCCTCC CAGCCTCTCC TTCAGTCTCT CTAAAGCAAG TAGAACAATA TGACCCCACA 
ACCAACAAAT GGACCATGGT AGCCCCACTC CGAGAAGGTG TCAGCAATGC TGCTGTAGTG 
AGCGCCAAGC TCAAGCTGTT CGCTTTCGGA GGTACCAGCG TAAGCCACGA CAAGCTTCCT 
AAGGTTCAGT GTTATGACCA GTGTGAAAAC AGATGGACAG TTCCAGCCAC CTGTCCCCAG 
CCCTGGCGTT ACACAGCCGC AGCTGTGCTG GGGAACCAGA TTTTTATCAT GGGTGGGGAT 
ACAGAATTCT CAGCCTGCTC TGCTTACAAG TTCAACAGTG AAACTTACCA GTGGACCAAG 
GTAGGAGACG TGACAGCCAA GCGCATGAGC TGCCATGCCG TGGCCTCCGG GAACAAGCTT 
TACGTGGTTG GAGGATACTT CGGCATTCAG CGCTGCAAGA CGTTGGACTG TTACGATCCG 
ACTTTAGATG TGTGGAACAG CATAACCACG GTTCCCTACT CTCTGATCCC TACCGCGTTC 
GTCAGCACCT GGAAACACCT GCCTTCCTAA