Stk10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stk10
Entrez Gene ID	29398
Full Name	serine/threonine kinase 10
General protein information	Preferred Names serine/threonine kinase 10 Names serine/threonine-protein kinase 10
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q12
Summary	an astrocyte gene which utilizes type 1 astrocyte-enriched cDNA library [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008767561.2	XP_008765783.1	serine/threonine-protein kinase 10 isoform X1
NM_019206.2	NP_062079.2	serine/threonine-protein kinase 10

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	STK10	XP_546239.2
Bos taurus (cattle)	STK10	NP_001179556.1
Rattus norvegicus (Norway rat)	Stk10	NP_062079.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010551	XP_314524.4
Homo sapiens (human)	STK10	NP_005981.3
Macaca mulatta (Rhesus monkey)	STK10	XP_002804682.1
Gallus gallus (chicken)	STK10	XP_414529.4
Caenorhabditis elegans (roundworm)	gck-4	NP_510290.1
Pan troglodytes (chimpanzee)	STK10	XP_518098.4
Mus musculus (house mouse)	Stk10	NP_033314.2
Danio rerio (zebrafish)	stk10	NP_957427.1
Drosophila melanogaster (fruit fly)	slik	NP_001014549.1
Xenopus tropicalis (tropical clawed frog)	stk10	NP_001072623.1

Gene Ontology
Bibliography

Related articles in PubMed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.
Belkina NV, Liu Y, Hao JJ, Karasuyama H, Shaw S
Proceedings of the National Academy of Sciences of the United States of America106(12)4707-12(2009 Mar)

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.
Pike AC, Rellos P, Niesen FH, Turnbull A, Oliver AW, Parker SA, Turk BE, Pearl LH, Knapp S
The EMBO journal27(4)704-14(2008 Feb)

Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.
Walter SA, Cutler RE Jr, Martinez R, Gishizky M, Hill RJ
The Journal of biological chemistry278(20)18221-8(2003 May)

Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes.
Endo J, Toyama-Sorimachi N, Taya C, Kuramochi-Miyagawa S, Nagata K, Kuida K, Takashi T, Yonekawa H, Yoshizawa Y, Miyasaka N, Karasuyama H
FEBS letters468(2-3)234-8(2000 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Stk10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stk10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04027	NM_019206.2 Latest version!	Rattus norvegicus serine/threonine kinase 10 (Stk10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa43263	XM_008767561.2 Latest version!	Rattus norvegicus serine/threonine kinase 10 (Stk10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stk10 ( NM_019206.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062079.2 Rattus norvegicus serine/threonine kinase 10 (Stk10), mRNA.

Price & Availability↑

CloneID	ORa04027
Clone ID Related Accession (Same CDS sequence)	NM_019206.2
Accession Version	NM_019206.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571587200000
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase 10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029242.1, AABR07029243.1 and AABR07029244.1. On or before Dec 16, 2009 this sequence version replaced XM_001065000.1, XM_001064952.1, XM_577078.2, NM_019206.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTTTCG CCAATTTTCG CCGCATCTTG CGGTTATCCA CCTTCGAGAA GAGAAAGTCC 
CGTGAATACG AGCATGTCCG CAGGGACCTG GACCCCAACG ACGTATGGGA GATCCTGGGC 
GAGCTGGGAG ACGGCGCCTT CGGCAAAGTC TACAAGGCCA AAAACAAGGA GACGGGCGCC 
CTGGCAGCAG CCAAAGTCAT TGAGACTAAG AGCGAGGAGG AGCTGGAGGA CTACATCGTG 
GAGATCGAGA TCCTCGCCAC CTGCGACCAC CCATATATCG TGAAGCTCCT GGGGGCCTAT 
TACTATGACG GGAAACTATG GATCATGATT GAGTTCTGCC CTGGGGGAGC TGTGGATGCC 
ATCATGCTAG AGCTGGATCG AGGCCTCACT GAGCCCCAGA TTCAGGTCGT TTGCCGCCAG 
ATGTTGGAGG CTCTCAACTT CCTGCACGGC AAGAGAATCA TCCACCGCGA CCTGAAAGCT 
GGCAACGTGC TTATGACCCT GGAGGGGGAC ATCAGGCTGG CTGATTTTGG AGTATCTGCC 
AAGAATCTGA AAACTCTGCA AAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCTGAGGTGG TGCTGTGTGA AACCATGAAG GACGCCCCCT ATGACTACAA GGCTGACATC 
TGGTCCCTGG GCATCACGCT GATCGAGATG GCGCAGATTG AGCCCCCACA CCATGAGCTC 
AACCCCATGC GGGTCCTGCT CAAGATCGCC AAGTCGGACC CTCCCACCCT GCTCACACCC 
TCCAAGTGGT CCACGGAGTT CCGAGACTTT CTGAAGATAG CCTTGGATAA GAACCCAGAA 
ACCCGGCCCA GTGCTGCGCA GCTGCTGCAG CATCCCTTCG TCAGTACAGT CACCAGTAAT 
AAGGCCCTTC GGGAGCTGGT GGCTGAGGCG AAGGCTGAGG TGATGGAGGA GATCGAGGAC 
GGCAAGGAGG ACGGCAGGGA GGACGGCAGG GAGGATGGAG AAGAGGAGGA TGGAGACGAG 
AAGGATGCTG TGAGTGCTGT TCCGCCCCCA GTCAACCACA CTCAGGACTC CTCTGCCAAT 
GGAACTCAGC CAAGCCTCAA CTCTGACAAG CTTCTCCAGG ATTCTTCTAC CCCCCTGCCT 
CCCAGCCAGC CTCAGGAGCC TGTGAACGGG CCCTGTAACC AACCCTCAGG GGATGGATCC 
CCCCAGAACA CCAGCCCTGC AGATGAGGTC TCCAAGAATG ACAATGGCTT AAAGGTACCT 
GTTCCCCTCC GGAAGTCCCG GCCATTGTCC GTGGATGCCA GAATTCAGGT GACCGAAGAG 
AAACAAATCA CTGACCAGGC TGAGAACCCC AGTTCTGCAG CCAGCAAACC CCCGAAGGTC 
AACCAGAGCC GACCTAACAG CAGCGCCCTG GAGACTTTGG GTGTCGAGAC TCTGGCCAAT 
GGAGGCCTGG AGCTCCCTGG CTCTGTAACT CCAAACCATT CTAAGAGGGC GTCGGACTGT 
AGCAACCTGT CTACCTCAGA GAGCATGGAC TACGGCACCT CCTTGTCTGC TGACCTGTCA 
TTGAACAAAG AGACGGGCTC ATTGTCTCTC AAGGGCTCAA AACTGCACAA CAAGACCCTG 
AAGAGGACCC GCCGGTTTGT GGTGGACGGT GTGGAGGTGA GCATCACCAC CTCCAAGATC 
ATCAGCGAAG ACGAGAAGAA AGACGAGGAG ATGAGGTTTC TCAGGCGCCA GGAACTCCGA 
GAGCTTCGGC TCCTGCAGAA AGAAGAGCAT CGGAACCAGA CGCAGCTGAG CACCAAGCAC 
GAGCTGCAGC TGGAGCAGAT GCACAGACGA TTTGAACAAG AAATCAACGC CAAGAAGAAA 
TTCTATGACG TGGAGCTAGA GAACCTGGAG CGGCAGCAGA AGCAGCAGGT GGAGAAGATG 
GAGCAGGACC ACAGCGTGCG TCGCAGAGAG GAGGCCAAGC GGATCCGCCT GGAGCAGGAT 
CGAGACTACG CCAGGTTCCA AGAGCAGCTC AAGCAGATGA AGAAGGAGGT GAAGCTGACT 
GTCGAGAGGT TGGCTAGAAA TAGTAGAAAT AGTTCTTCCT TCCAGGAACA GACTGAGCAT 
CCTCAGGCAG CTAGGAGGAG GGACCGAGAC TTTGTAGCCA AGCAGAAGGA AGACCTGGAG 
CTGGCCATGA AGAAGCTCAC GGCAGAAAAC AGGCGTGAGA TCTGTGACAA GGAACGTGAT 
TGCCTTAACA AGAAGCAGGA GCTCCTCCGA GACCGAGAGG CAGCCCTGTG GGAGATGGAG 
GAGCACCAGT TACAGGAGAG ACATCAGCTG GTGAAGCAGC AGCTTAAGGA CCAGTACTTC 
CTGCAGCGGC ATGACCTGCT GCGCAAGCAC GAGAAGGAGC GGGAGCAGAT GCAGCGCTAC 
AACCAGCGTA TGATGGAGCA GCTGAAGGTC AGACAGCAGC AGGAGAAGGC GCGGCTACCC 
AAGATCCAGA GGAGTGACGG CAAGACCCGC ATGGCCATGT ACAAGAAGAG CCTGCACATC 
AATGGTGCGG GCAGTGCCTC CGAGCAGCGG GAGAAGGTCA AGCAGTTCTC CCAGCAGGAA 
GAGAAGAGGC AGAAGGCGGA GAGGCTGCAG CAGCAGCAGA AACACGAGAA CCAGATGCGA 
GACATGGTGG CACAGTGCGA GAGCAACATG AACGAGCTGC AGCAGCTGCA GAATGAAAAG 
TGTCATCTGT TAGTGGAGCA TGAAACCCAG AAGCTGAAGG CCCTGGACGA GAGCCATAAC 
CAGAGCCTGA AGGAATGGCG AGACAAGCTT CGGCCACGCA AAAAGGCCCT GGAAGAGGAT 
TTGAACCAGA AGAAGCGGGA ACAGGAAATG TTCTTCAGAC TAAGTGAGGA GGCAGAGACC 
AGACCCACCA CACCCAACAG AGCCAGCAAG TTCTTCCCCT ACAGCTCTGG GGATGCTTCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062079.2
CDS	107..3049
Translation	MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQLLQHPFVSTVTSNKALRELVAEAKAEVMEEIEDGKEDGREDGREDGEEEDGDEKDAVSAVPPPVNHTQDSSANGTQPSLNSDKLLQDSSTPLPPSQPQEPVNGPCNQPSGDGSPQNTSPADEVSKNDNGLKVPVPLRKSRPLSVDARIQVTEEKQITDQAENPSSAASKPPKVNQSRPNSSALETLGVETLANGGLELPGSVTPNHSKRASDCSNLSTSESMDYGTSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSTKHELQLEQMHRRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYARFQEQLKQMKKEVKLTVERLARNSRNSSSFQEQTEHPQAARRRDRDFVAKQKEDLELAMKKLTAENRREICDKERDCLNKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHINGAGSASEQREKVKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMNELQQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLRPRKKALEEDLNQKKREQEMFFRLSEEAETRPTTPNRASKFFPYSSGDAS

Target ORF information:

RefSeq Version	NM_019206.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus serine/threonine kinase 10 (Stk10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019206.2

ORF Insert Sequence:

ATGGCTTTCG CCAATTTTCG CCGCATCTTG CGGTTATCCA CCTTCGAGAA GAGAAAGTCC 
CGTGAATACG AGCATGTCCG CAGGGACCTG GACCCCAACG ACGTATGGGA GATCCTGGGC 
GAGCTGGGAG ACGGCGCCTT CGGCAAAGTC TACAAGGCCA AAAACAAGGA GACGGGCGCC 
CTGGCAGCAG CCAAAGTCAT TGAGACTAAG AGCGAGGAGG AGCTGGAGGA CTACATCGTG 
GAGATCGAGA TCCTCGCCAC CTGCGACCAC CCATATATCG TGAAGCTCCT GGGGGCCTAT 
TACTATGACG GGAAACTATG GATCATGATT GAGTTCTGCC CTGGGGGAGC TGTGGATGCC 
ATCATGCTAG AGCTGGATCG AGGCCTCACT GAGCCCCAGA TTCAGGTCGT TTGCCGCCAG 
ATGTTGGAGG CTCTCAACTT CCTGCACGGC AAGAGAATCA TCCACCGCGA CCTGAAAGCT 
GGCAACGTGC TTATGACCCT GGAGGGGGAC ATCAGGCTGG CTGATTTTGG AGTATCTGCC 
AAGAATCTGA AAACTCTGCA AAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCTGAGGTGG TGCTGTGTGA AACCATGAAG GACGCCCCCT ATGACTACAA GGCTGACATC 
TGGTCCCTGG GCATCACGCT GATCGAGATG GCGCAGATTG AGCCCCCACA CCATGAGCTC 
AACCCCATGC GGGTCCTGCT CAAGATCGCC AAGTCGGACC CTCCCACCCT GCTCACACCC 
TCCAAGTGGT CCACGGAGTT CCGAGACTTT CTGAAGATAG CCTTGGATAA GAACCCAGAA 
ACCCGGCCCA GTGCTGCGCA GCTGCTGCAG CATCCCTTCG TCAGTACAGT CACCAGTAAT 
AAGGCCCTTC GGGAGCTGGT GGCTGAGGCG AAGGCTGAGG TGATGGAGGA GATCGAGGAC 
GGCAAGGAGG ACGGCAGGGA GGACGGCAGG GAGGATGGAG AAGAGGAGGA TGGAGACGAG 
AAGGATGCTG TGAGTGCTGT TCCGCCCCCA GTCAACCACA CTCAGGACTC CTCTGCCAAT 
GGAACTCAGC CAAGCCTCAA CTCTGACAAG CTTCTCCAGG ATTCTTCTAC CCCCCTGCCT 
CCCAGCCAGC CTCAGGAGCC TGTGAACGGG CCCTGTAACC AACCCTCAGG GGATGGATCC 
CCCCAGAACA CCAGCCCTGC AGATGAGGTC TCCAAGAATG ACAATGGCTT AAAGGTACCT 
GTTCCCCTCC GGAAGTCCCG GCCATTGTCC GTGGATGCCA GAATTCAGGT GACCGAAGAG 
AAACAAATCA CTGACCAGGC TGAGAACCCC AGTTCTGCAG CCAGCAAACC CCCGAAGGTC 
AACCAGAGCC GACCTAACAG CAGCGCCCTG GAGACTTTGG GTGTCGAGAC TCTGGCCAAT 
GGAGGCCTGG AGCTCCCTGG CTCTGTAACT CCAAACCATT CTAAGAGGGC GTCGGACTGT 
AGCAACCTGT CTACCTCAGA GAGCATGGAC TACGGCACCT CCTTGTCTGC TGACCTGTCA 
TTGAACAAAG AGACGGGCTC ATTGTCTCTC AAGGGCTCAA AACTGCACAA CAAGACCCTG 
AAGAGGACCC GCCGGTTTGT GGTGGACGGT GTGGAGGTGA GCATCACCAC CTCCAAGATC 
ATCAGCGAAG ACGAGAAGAA AGACGAGGAG ATGAGGTTTC TCAGGCGCCA GGAACTCCGA 
GAGCTTCGGC TCCTGCAGAA AGAAGAGCAT CGGAACCAGA CGCAGCTGAG CACCAAGCAC 
GAGCTGCAGC TGGAGCAGAT GCACAGACGA TTTGAACAAG AAATCAACGC CAAGAAGAAA 
TTCTATGACG TGGAGCTAGA GAACCTGGAG CGGCAGCAGA AGCAGCAGGT GGAGAAGATG 
GAGCAGGACC ACAGCGTGCG TCGCAGAGAG GAGGCCAAGC GGATCCGCCT GGAGCAGGAT 
CGAGACTACG CCAGGTTCCA AGAGCAGCTC AAGCAGATGA AGAAGGAGGT GAAGCTGACT 
GTCGAGAGGT TGGCTAGAAA TAGTAGAAAT AGTTCTTCCT TCCAGGAACA GACTGAGCAT 
CCTCAGGCAG CTAGGAGGAG GGACCGAGAC TTTGTAGCCA AGCAGAAGGA AGACCTGGAG 
CTGGCCATGA AGAAGCTCAC GGCAGAAAAC AGGCGTGAGA TCTGTGACAA GGAACGTGAT 
TGCCTTAACA AGAAGCAGGA GCTCCTCCGA GACCGAGAGG CAGCCCTGTG GGAGATGGAG 
GAGCACCAGT TACAGGAGAG ACATCAGCTG GTGAAGCAGC AGCTTAAGGA CCAGTACTTC 
CTGCAGCGGC ATGACCTGCT GCGCAAGCAC GAGAAGGAGC GGGAGCAGAT GCAGCGCTAC 
AACCAGCGTA TGATGGAGCA GCTGAAGGTC AGACAGCAGC AGGAGAAGGC GCGGCTACCC 
AAGATCCAGA GGAGTGACGG CAAGACCCGC ATGGCCATGT ACAAGAAGAG CCTGCACATC 
AATGGTGCGG GCAGTGCCTC CGAGCAGCGG GAGAAGGTCA AGCAGTTCTC CCAGCAGGAA 
GAGAAGAGGC AGAAGGCGGA GAGGCTGCAG CAGCAGCAGA AACACGAGAA CCAGATGCGA 
GACATGGTGG CACAGTGCGA GAGCAACATG AACGAGCTGC AGCAGCTGCA GAATGAAAAG 
TGTCATCTGT TAGTGGAGCA TGAAACCCAG AAGCTGAAGG CCCTGGACGA GAGCCATAAC 
CAGAGCCTGA AGGAATGGCG AGACAAGCTT CGGCCACGCA AAAAGGCCCT GGAAGAGGAT 
TTGAACCAGA AGAAGCGGGA ACAGGAAATG TTCTTCAGAC TAAGTGAGGA GGCAGAGACC 
AGACCCACCA CACCCAACAG AGCCAGCAAG TTCTTCCCCT ACAGCTCTGG GGATGCTTCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Stk10 ( XM_008767561.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765783.1 Rattus norvegicus serine/threonine kinase 10 (Stk10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43263
Clone ID Related Accession (Same CDS sequence)	XM_008767561.2
Accession Version	XM_008767561.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) and transcript sequence (U33472.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767561.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 90 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGGCTTTCG CCAATTTTCG CCGCATCTTG CGGTTATCCA CCTTCGAGAA GAGAAAGTCC 
CGTGAATACG AGCATGTCCG CAGGGACCTG GACCCCAACG ACGTATGGGA GATCCTGGGC 
GAGCTGGGAG ACGGCGCCTT CGGCAAAGTC TACAAGGCCA AAAACAAGGA GACGGGCGCC 
CTGGCAGCAG CCAAAGTCAT TGAGACTAAG AGCGAGGAGG AGCTGGAGGA CTACATCGTG 
GAGATCGAGA TCCTCGCCAC CTGCGACCAC CCATATATCG TGAAGCTCCT GGGGGCCTAT 
TACTATGACG GGAAACTATG GATCATGATT GAGTTCTGCC CTGGGGGAGC TGTGGATGCC 
ATCATGCTAG AGCTGGATCG AGGCCTCACT GAGCCCCAGA TTCAGGTCGT TTGCCGCCAG 
ATGTTGGAGG CTCTCAACTT CCTGCACGGC AAGAGAATCA TCCACCGCGA CCTGAAAGCT 
GGCAACGTGC TTATGACCCT GGAGGGGGAC ATCAGGCTGG CTGATTTTGG AGTATCTGCC 
AAGAATCTGA AAACTCTGCA AAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCTGAGGTGG TGCTGTGTGA AACCATGAAG GACGCCCCCT ATGACTACAA GGCTGACATC 
TGGTCCCTGG GCATCACGCT GATCGAGATG GCGCAGATTG AGCCCCCACA CCATGAGCTC 
AACCCCATGC GGGTCCTGCT CAAGATCGCC AAGTCGGACC CTCCCACCCT GCTCACACCC 
TCCAAGTGGT CCACGGAGTT CCGAGACTTT CTGAAGATAG CCTTGGATAA GAACCCAGAA 
ACCCGGCCCA GTGCTGCGCA GCTGCTGCAG CATCCCTTCG TCAGTACAGT CACCAGTAAT 
AAGGCCCTTC GGGAGCTGGT GGCTGAGGCG AAGGCTGAGG TGATGGAGGA GATCGAGGAC 
GGCAAGGAGG ACGGCAGGGA GGACGGCAGG GAGGATGGAG AAGAGGAGGA TGGAGACGAG 
AAGGATGCTG TGAGTGCTGT TCCGCCCCCA GTCAACCACA CTCAGGACTC CTCTGCCAAT 
GGAACTCAGC CAAGCCTCAA CTCTGACAAG CTTCTCCAGG ATTCTTCTAC CCCCCTGCCT 
CCCAGCCAGC CTCAGGAGCC TGTGAACGGG CCCTGTAACC AACCCTCAGG GGATGGATCC 
CCCCAGAACA CCAGCCCTGC AGATGAGGTC TCCAAGAATG ACAATGGCTT AAAGGTACCT 
GTTCCCCTCC GGAAGTCCCG GCCATTGTCC GTGGATGCCA GAATTCAGGT GACCGAAGAG 
AAACAAATCA CTGACCAGGC TGAGAACCCC AGTTCTGCAG CCAGCAAACC CCCGAAGGTC 
AACCAGAGCC GACCTAACAG CAGCGCCCTG GAGACTTTGG GTGTCGAGAC TCTGGCCAAT 
GGAGGCCTGG AGCTCCCTGG CTCTGTAACT CCAAACCATT CTAAGAGGGC GTCGGACTGT 
AGCAACCTGT CTACCTCAGA GAGCATGGAC TACGGCACCT CCTTGTCTGC TGACCTGTCA 
TTGAACAAAG AGACGGGCTC ATTGTCTCTC AAGGGCTCAA AACTGCACAA CAAGACCCTG 
AAGAGGACCC GCCGGTTTGT GGTGGACGGT GTGGAGGTGA GCATCACCAC CTCCAAGATC 
ATCAGCGAAG ACGAGAAGAA AGACGAGGAG ATGAGGTTTC TCAGGCGCCA GGAACTCCGA 
GAGCTTCGGC TCCTGCAGAA AGAAGAGCAT CGGAACCAGA CGCAGCTGAG CACCAAGCAC 
GAGCTGCAGC TGGAGCAGAT GCACAGACGA TTTGAACAAG AAATCAACGC CAAGAAGAAA 
TTCTATGACG TGGAGCTAGA GAACCTGGAG CGGCAGCAGA AGCAGCAGGT GGAGAAGATG 
GAGCAGGACC ACAGCGTGCG TCGCAGAGAG GAGGCCAAGC GGATCCGCCT GGAGCAGGAT 
CGAGACTACG CCAGGTTCCA AGAGCAGCTC AAGCAGATGA AGAAGGAGGT GAAGAATGAG 
GTTGAGAAAC TGCCCCGGCA ACAGCGGAAG GAGAGCATGA AGCAGAAGAT GGAGGAGCAC 
GCACAGAAGA AACAACTGCT GGACCGAGAC TTTGTAGCCA AGCAGAAGGA AGACCTGGAG 
CTGGCCATGA AGAAGCTCAC GGCAGAAAAC AGGCGTGAGA TCTGTGACAA GGAACGTGAT 
TGCCTTAACA AGAAGCAGGA GCTCCTCCGA GACCGAGAGG CAGCCCTGTG GGAGATGGAG 
GAGCACCAGT TACAGGAGAG ACATCAGCTG GTGAAGCAGC AGCTTAAGGA CCAGTACTTC 
CTGCAGCGGC ATGACCTGCT GCGCAAGCAC GAGAAGGAGC GGGAGCAGAT GCAGCGCTAC 
AACCAGCGTA TGATGGAGCA GCTGAAGGTC AGACAGCAGC AGGAGAAGGC GCGGCTACCC 
AAGATCCAGA GGAGTGACGG CAAGACCCGC ATGGCCATGT ACAAGAAGAG CCTGCACATC 
AATGGTGCGG GCAGTGCCTC CGAGCAGCGG GAGAAGGTCA AGCAGTTCTC CCAGCAGGAA 
GAGAAGAGGC AGAAGGCGGA GAGGCTGCAG CAGCAGCAGA AACACGAGAA CCAGATGCGA 
GACATGGTGG CACAGTGCGA GAGCAACATG AACGAGCTGC AGCAGCTGCA GAATGAAAAG 
TGTCATCTGT TAGTGGAGCA TGAAACCCAG AAGCTGAAGG CCCTGGACGA GAGCCATAAC 
CAGAGCCTGA AGGAATGGCG AGACAAGCTT CGGCCACGCA AAAAGGCCCT GGAAGAGGAT 
TTGAACCAGA AGAAGCGGGA ACAGGAAATG TTCTTCAGAC TAAGTGAGGA GGCAGAGACC 
AGACCCACCA CACCCAACAG AGCCAGCAAG TTCTTCCCCT ACAGCTCTGG GGATGCTTCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765783.1
CDS	112..3054
Translation	MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSTEFRDFLKIALDKNPETRPSAAQLLQHPFVSTVTSNKALRELVAEAKAEVMEEIEDGKEDGREDGREDGEEEDGDEKDAVSAVPPPVNHTQDSSANGTQPSLNSDKLLQDSSTPLPPSQPQEPVNGPCNQPSGDGSPQNTSPADEVSKNDNGLKVPVPLRKSRPLSVDARIQVTEEKQITDQAENPSSAASKPPKVNQSRPNSSALETLGVETLANGGLELPGSVTPNHSKRASDCSNLSTSESMDYGTSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSTKHELQLEQMHRRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYARFQEQLKQMKKEVKNEVEKLPRQQRKESMKQKMEEHAQKKQLLDRDFVAKQKEDLELAMKKLTAENRREICDKERDCLNKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHINGAGSASEQREKVKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMNELQQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLRPRKKALEEDLNQKKREQEMFFRLSEEAETRPTTPNRASKFFPYSSGDAS

Target ORF information:

RefSeq Version	XM_008767561.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus serine/threonine kinase 10 (Stk10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767561.2

ORF Insert Sequence:

ATGGCTTTCG CCAATTTTCG CCGCATCTTG CGGTTATCCA CCTTCGAGAA GAGAAAGTCC 
CGTGAATACG AGCATGTCCG CAGGGACCTG GACCCCAACG ACGTATGGGA GATCCTGGGC 
GAGCTGGGAG ACGGCGCCTT CGGCAAAGTC TACAAGGCCA AAAACAAGGA GACGGGCGCC 
CTGGCAGCAG CCAAAGTCAT TGAGACTAAG AGCGAGGAGG AGCTGGAGGA CTACATCGTG 
GAGATCGAGA TCCTCGCCAC CTGCGACCAC CCATATATCG TGAAGCTCCT GGGGGCCTAT 
TACTATGACG GGAAACTATG GATCATGATT GAGTTCTGCC CTGGGGGAGC TGTGGATGCC 
ATCATGCTAG AGCTGGATCG AGGCCTCACT GAGCCCCAGA TTCAGGTCGT TTGCCGCCAG 
ATGTTGGAGG CTCTCAACTT CCTGCACGGC AAGAGAATCA TCCACCGCGA CCTGAAAGCT 
GGCAACGTGC TTATGACCCT GGAGGGGGAC ATCAGGCTGG CTGATTTTGG AGTATCTGCC 
AAGAATCTGA AAACTCTGCA AAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 
CCTGAGGTGG TGCTGTGTGA AACCATGAAG GACGCCCCCT ATGACTACAA GGCTGACATC 
TGGTCCCTGG GCATCACGCT GATCGAGATG GCGCAGATTG AGCCCCCACA CCATGAGCTC 
AACCCCATGC GGGTCCTGCT CAAGATCGCC AAGTCGGACC CTCCCACCCT GCTCACACCC 
TCCAAGTGGT CCACGGAGTT CCGAGACTTT CTGAAGATAG CCTTGGATAA GAACCCAGAA 
ACCCGGCCCA GTGCTGCGCA GCTGCTGCAG CATCCCTTCG TCAGTACAGT CACCAGTAAT 
AAGGCCCTTC GGGAGCTGGT GGCTGAGGCG AAGGCTGAGG TGATGGAGGA GATCGAGGAC 
GGCAAGGAGG ACGGCAGGGA GGACGGCAGG GAGGATGGAG AAGAGGAGGA TGGAGACGAG 
AAGGATGCTG TGAGTGCTGT TCCGCCCCCA GTCAACCACA CTCAGGACTC CTCTGCCAAT 
GGAACTCAGC CAAGCCTCAA CTCTGACAAG CTTCTCCAGG ATTCTTCTAC CCCCCTGCCT 
CCCAGCCAGC CTCAGGAGCC TGTGAACGGG CCCTGTAACC AACCCTCAGG GGATGGATCC 
CCCCAGAACA CCAGCCCTGC AGATGAGGTC TCCAAGAATG ACAATGGCTT AAAGGTACCT 
GTTCCCCTCC GGAAGTCCCG GCCATTGTCC GTGGATGCCA GAATTCAGGT GACCGAAGAG 
AAACAAATCA CTGACCAGGC TGAGAACCCC AGTTCTGCAG CCAGCAAACC CCCGAAGGTC 
AACCAGAGCC GACCTAACAG CAGCGCCCTG GAGACTTTGG GTGTCGAGAC TCTGGCCAAT 
GGAGGCCTGG AGCTCCCTGG CTCTGTAACT CCAAACCATT CTAAGAGGGC GTCGGACTGT 
AGCAACCTGT CTACCTCAGA GAGCATGGAC TACGGCACCT CCTTGTCTGC TGACCTGTCA 
TTGAACAAAG AGACGGGCTC ATTGTCTCTC AAGGGCTCAA AACTGCACAA CAAGACCCTG 
AAGAGGACCC GCCGGTTTGT GGTGGACGGT GTGGAGGTGA GCATCACCAC CTCCAAGATC 
ATCAGCGAAG ACGAGAAGAA AGACGAGGAG ATGAGGTTTC TCAGGCGCCA GGAACTCCGA 
GAGCTTCGGC TCCTGCAGAA AGAAGAGCAT CGGAACCAGA CGCAGCTGAG CACCAAGCAC 
GAGCTGCAGC TGGAGCAGAT GCACAGACGA TTTGAACAAG AAATCAACGC CAAGAAGAAA 
TTCTATGACG TGGAGCTAGA GAACCTGGAG CGGCAGCAGA AGCAGCAGGT GGAGAAGATG 
GAGCAGGACC ACAGCGTGCG TCGCAGAGAG GAGGCCAAGC GGATCCGCCT GGAGCAGGAT 
CGAGACTACG CCAGGTTCCA AGAGCAGCTC AAGCAGATGA AGAAGGAGGT GAAGAATGAG 
GTTGAGAAAC TGCCCCGGCA ACAGCGGAAG GAGAGCATGA AGCAGAAGAT GGAGGAGCAC 
GCACAGAAGA AACAACTGCT GGACCGAGAC TTTGTAGCCA AGCAGAAGGA AGACCTGGAG 
CTGGCCATGA AGAAGCTCAC GGCAGAAAAC AGGCGTGAGA TCTGTGACAA GGAACGTGAT 
TGCCTTAACA AGAAGCAGGA GCTCCTCCGA GACCGAGAGG CAGCCCTGTG GGAGATGGAG 
GAGCACCAGT TACAGGAGAG ACATCAGCTG GTGAAGCAGC AGCTTAAGGA CCAGTACTTC 
CTGCAGCGGC ATGACCTGCT GCGCAAGCAC GAGAAGGAGC GGGAGCAGAT GCAGCGCTAC 
AACCAGCGTA TGATGGAGCA GCTGAAGGTC AGACAGCAGC AGGAGAAGGC GCGGCTACCC 
AAGATCCAGA GGAGTGACGG CAAGACCCGC ATGGCCATGT ACAAGAAGAG CCTGCACATC 
AATGGTGCGG GCAGTGCCTC CGAGCAGCGG GAGAAGGTCA AGCAGTTCTC CCAGCAGGAA 
GAGAAGAGGC AGAAGGCGGA GAGGCTGCAG CAGCAGCAGA AACACGAGAA CCAGATGCGA 
GACATGGTGG CACAGTGCGA GAGCAACATG AACGAGCTGC AGCAGCTGCA GAATGAAAAG 
TGTCATCTGT TAGTGGAGCA TGAAACCCAG AAGCTGAAGG CCCTGGACGA GAGCCATAAC 
CAGAGCCTGA AGGAATGGCG AGACAAGCTT CGGCCACGCA AAAAGGCCCT GGAAGAGGAT 
TTGAACCAGA AGAAGCGGGA ACAGGAAATG TTCTTCAGAC TAAGTGAGGA GGCAGAGACC 
AGACCCACCA CACCCAACAG AGCCAGCAAG TTCTTCCCCT ACAGCTCTGG GGATGCTTCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America106(12)4707-12(2009 Mar)
Belkina NV,Liu Y,Hao JJ,Karasuyama H,Shaw S

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.
The EMBO journal27(4)704-14(2008 Feb)
Pike AC,Rellos P,Niesen FH,Turnbull A,Oliver AW,Parker SA,Turk BE,Pearl LH,Knapp S

Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.
The Journal of biological chemistry278(20)18221-8(2003 May)
Walter SA,Cutler RE Jr,Martinez R,Gishizky M,Hill RJ

Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes.
FEBS letters468(2-3)234-8(2000 Feb)
Endo J,Toyama-Sorimachi N,Taya C,Kuramochi-Miyagawa S,Nagata K,Kuida K,Takashi T,Yonekawa H,Yoshizawa Y,Miyasaka N,Karasuyama H

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Stk10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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