Zfp36l1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zfp36l1
Entrez Gene ID	29344
Full Name	zinc finger protein 36, C3H type-like 1
Synonyms	Berg36,Brf1,ERF1,TIS11b,cMG1
General protein information	Preferred Names zinc finger protein 36, C3H type-like 1 Names mRNA decay activator protein ZFP36L1 EGF-inducible protein CMG1 TPA-induced sequence 11b ZFP36-like 1 butyrate response factor 1 zinc finger protein 36, C3H1 type-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q24
Summary	putative nuclear transcription factor; member of the TIS11 family of early response genes; may regulate the response to growth factors [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017172.1	NP_058868.1	mRNA decay activator protein ZFP36L1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ZFP36L1	XP_003314464.2
Homo sapiens (human)	ZFP36L1	NP_001231630.1
Canis lupus familiaris (dog)	ZFP36L1	XP_005623625.1
Bos taurus (cattle)	ZFP36L1	NP_001094704.1
Xenopus tropicalis (tropical clawed frog)	zfp36l1	NP_001072758.1
Danio rerio (zebrafish)	zfp36l1a	NP_001070621.1
Mus musculus (house mouse)	Zfp36l1	NP_031590.1
Rattus norvegicus (Norway rat)	Zfp36l1	NP_058868.1
Gallus gallus (chicken)	ZFP36L1	XP_004951161.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional analysis of ZFP36 proteins in keratinocytes.
Prenzler F, Fragasso A, Schmitt A, Munz B
European journal of cell biology95(8)277-84(2016 Aug)

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.
Galloway A, Saveliev A, Łukasiak S, Hodson DJ, Bolland D, Balmanno K, Ahlfors H, Monzón-Casanova E, Mannurita SC, Bell LS, Andrews S, Díaz-Muñoz MD, Cook SJ, Corcoran A, Turner M
Science (New York, N.Y.)352(6284)453-9(2016 Apr)

ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Chen MT, Dong L, Zhang XH, Yin XL, Ning HM, Shen C, Su R, Li F, Song L, Ma YN, Wang F, Zhao HL, Yu J, Zhang JW
Scientific reports516229(2015 Nov)

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T
Nucleic acids research42(15)10037-49(2014 Sep)

Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.
Zekavati A, Nasir A, Alcaraz A, Aldrovandi M, Marsh P, Norton JD, Murphy JJ
PloS one9(7)e102625(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zfp36l1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zfp36l1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42730	NM_017172.1 Latest version!	Rattus norvegicus zinc finger protein 36, C3H type-like 1 (Zfp36l1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zfp36l1 ( NM_017172.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058868.1 Rattus norvegicus zinc finger protein 36, C3H type-like 1 (Zfp36l1), mRNA.

Price & Availability↑

CloneID	ORa42730
Clone ID Related Accession (Same CDS sequence)	NM_017172.1
Accession Version	NM_017172.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Rattus norvegicus(Norway rat)
Product	mRNA decay activator protein ZFP36L1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X52590.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52590.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACCACCA CCCTCGTGTC CGCCACCATT TTCGACTTGA GCGAAGTTTT ATGCAAGGGT 
AACAAGATGC TCAACTACAG CACTCCCAGT GCTGGGGGCT GCCTGCTGGA CAGGAAGGCA 
GTGGGCACCC CTGCTGGCGG GGGCTTCCCT CGGAGGCACT CGGTCACTCT GCCCAGCTCC 
AAGTTCCATC AGAACCAGCT TCTCAGCAGT CTTAAGGGTG AGCCGGCCCC GACCCTGAGC 
TCACGCGACA GCCGCTTTCG AGACCGCTCT TTCTCCGAAG GGGGCGAGCG GCTGCTGCCC 
ACTCAGAAGC AGCCTGGGAG CGGCCAGGTC AACTCCAGCC GCTACAAAAC GGAGCTGTGC 
CGCCCCTTCG AAGAAAACGG TGCCTGTAAG TACGGGGACA AGTGCCAGTT CGCGCACGGC 
ATCCACGAGC TCCGCAGCCT GACCCGCCAC CCCAAGTACA AGACGGAGCT GTGCCGCACC 
TTCCACACCA TCGGCTTTTG CCCTTATGGG CCCCGCTGCC ACTTCATTCA CAACGCCGAG 
GAGCGACGCG CCCTGGCGGG GGGCCGGGAC CTCTCCGCTG ACCGTCCCCG CCTCCAGCAT 
AGCTTTAGCT TTGCTGGGTT TCCCAGTGCC GCTGCCACCG CCGCTGCCAC GGGGCTGCTG 
GACAGCCCCA CGTCCATCAC CCCACCCCCC ATCCTGAGCG CCGATGACCT CTTGGGCTCA 
CCTACCCTGC CCGATGGCAC CAATAACCCC TTCGCCTTTT CCAGCCAGGA GCTGGCGAGC 
CTCTTTGCTC CTAGCATGGG GCTGCCCGGG GGAGGCTCCC CCACCACCTT CCTCTTCCGG 
CCTATGTCCG AATCCCCTCA CATGTTTGAC TCTCCCCCCA GCCCTCAGGA TTCTCTCTCG 
GACCATGAGG GCTACCTGAG CAGCTCCAGC AGCAGCCACA GTGGCTCAGA CTCCCCTACC 
TTGGACAACT CAAGACGCCT GCCCATTTTC AGCAGACTCT CCATCTCAGA TGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058868.1
CDS	114..1130
Translation	MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPTLSSRDSRFRDRSFSEGGERLLPTQKQPGSGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRALAGGRDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD

Target ORF information:

RefSeq Version	NM_017172.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 36, C3H type-like 1 (Zfp36l1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017172.1

ORF Insert Sequence:

ATGACCACCA CCCTCGTGTC CGCCACCATT TTCGACTTGA GCGAAGTTTT ATGCAAGGGT 
AACAAGATGC TCAACTACAG CACTCCCAGT GCTGGGGGCT GCCTGCTGGA CAGGAAGGCA 
GTGGGCACCC CTGCTGGCGG GGGCTTCCCT CGGAGGCACT CGGTCACTCT GCCCAGCTCC 
AAGTTCCATC AGAACCAGCT TCTCAGCAGT CTTAAGGGTG AGCCGGCCCC GACCCTGAGC 
TCACGCGACA GCCGCTTTCG AGACCGCTCT TTCTCCGAAG GGGGCGAGCG GCTGCTGCCC 
ACTCAGAAGC AGCCTGGGAG CGGCCAGGTC AACTCCAGCC GCTACAAAAC GGAGCTGTGC 
CGCCCCTTCG AAGAAAACGG TGCCTGTAAG TACGGGGACA AGTGCCAGTT CGCGCACGGC 
ATCCACGAGC TCCGCAGCCT GACCCGCCAC CCCAAGTACA AGACGGAGCT GTGCCGCACC 
TTCCACACCA TCGGCTTTTG CCCTTATGGG CCCCGCTGCC ACTTCATTCA CAACGCCGAG 
GAGCGACGCG CCCTGGCGGG GGGCCGGGAC CTCTCCGCTG ACCGTCCCCG CCTCCAGCAT 
AGCTTTAGCT TTGCTGGGTT TCCCAGTGCC GCTGCCACCG CCGCTGCCAC GGGGCTGCTG 
GACAGCCCCA CGTCCATCAC CCCACCCCCC ATCCTGAGCG CCGATGACCT CTTGGGCTCA 
CCTACCCTGC CCGATGGCAC CAATAACCCC TTCGCCTTTT CCAGCCAGGA GCTGGCGAGC 
CTCTTTGCTC CTAGCATGGG GCTGCCCGGG GGAGGCTCCC CCACCACCTT CCTCTTCCGG 
CCTATGTCCG AATCCCCTCA CATGTTTGAC TCTCCCCCCA GCCCTCAGGA TTCTCTCTCG 
GACCATGAGG GCTACCTGAG CAGCTCCAGC AGCAGCCACA GTGGCTCAGA CTCCCCTACC 
TTGGACAACT CAAGACGCCT GCCCATTTTC AGCAGACTCT CCATCTCAGA TGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional analysis of ZFP36 proteins in keratinocytes.
European journal of cell biology95(8)277-84(2016 Aug)
Prenzler F,Fragasso A,Schmitt A,Munz B

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.
Science (New York, N.Y.)352(6284)453-9(2016 Apr)
Galloway A,Saveliev A,Łukasiak S,Hodson DJ,Bolland D,Balmanno K,Ahlfors H,Monzón-Casanova E,Mannurita SC,Bell LS,Andrews S,Díaz-Muñoz MD,Cook SJ,Corcoran A,Turner M

ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Scientific reports516229(2015 Nov)
Chen MT,Dong L,Zhang XH,Yin XL,Ning HM,Shen C,Su R,Li F,Song L,Ma YN,Wang F,Zhao HL,Yu J,Zhang JW

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Nucleic acids research42(15)10037-49(2014 Sep)
Adachi S,Homoto M,Tanaka R,Hioki Y,Murakami H,Suga H,Matsumoto M,Nakayama KI,Hatta T,Iemura S,Natsume T

Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.
PloS one9(7)e102625(2014)
Zekavati A,Nasir A,Alcaraz A,Aldrovandi M,Marsh P,Norton JD,Murphy JJ

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Zfp36l1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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