Cd46 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd46
Entrez Gene ID	29333
Full Name	CD46 molecule
Synonyms	Mcp
General protein information	Preferred Names CD46 molecule Names membrane cofactor protein CD46 antigen, complement regulatory protein CD46 molecule, complement regulatory protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q27
Summary	may be involved in fertilization or reproduction; human homolog acts as an inhibitor of plasma membrane complement [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006250478.3	XP_006250540.1	membrane cofactor protein isoform X2
XM_008769849.2	XP_008768071.1	membrane cofactor protein isoform X1
NM_019190.1	NP_062063.1	membrane cofactor protein precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CD46	NP_722548.1
Macaca mulatta (Rhesus monkey)	CD46	XP_001111698.2
Rattus norvegicus (Norway rat)	Cd46	NP_062063.1
Pan troglodytes (chimpanzee)	CD46	XP_001167573.2
Bos taurus (cattle)	CD46	XP_002694273.2
Mus musculus (house mouse)	Cd46	NP_034908.1
Canis lupus familiaris (dog)	LOC102156626	XP_005622373.1

Gene Ontology
Bibliography

Related articles in PubMed

Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism.
Lewis DA, Suchindran S, Beckman MG, Hooper WC, Grant AM, Heit JA, Manco-Johnson M, Moll S, Philipp CS, Kenney K, De Staercke C, Pyle ME, Chi JT, Ortel TL
Thrombosis research135(4)659-65(2015 Apr)

Genetic analysis of membrane cofactor protein (CD46) of the complement system in women with and without preeclamptic pregnancies.
Lokki AI, Aalto-Viljakainen T, Meri S, Laivuori H,
PloS one10(2)e0117840(2015)

Use of complement regulators, CD35, CD46, CD55, and CD59, on leukocytes as markers for diagnosis of viral and bacterial infections.
Nuutila J, Jalava-Karvinen P, Hohenthal U, Kotilainen P, Pelliniemi TT, Nikoskelainen J, Lilius EM
Human immunology74(5)522-30(2013 May)

The CD46-Jagged1 interaction is critical for human TH1 immunity.
Le Friec G, Sheppard D, Whiteman P, Karsten CM, Shamoun SA, Laing A, Bugeon L, Dallman MJ, Melchionna T, Chillakuri C, Smith RA, Drouet C, Couzi L, Fremeaux-Bacchi V, Köhl J, Waddington SN, McDonnell JM, Baker A, Handford PA, Lea SM, Kemper C
Nature immunology13(12)1213-21(2012 Dec)

Complement inhibitory proteins expression in placentas of thrombophilic women.
Wirstlein PK, Jasiński P, Rajewski M, Goździewicz T, Skrzypczak J
Folia histochemica et cytobiologica50(3)460-7(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cd46 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd46 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03982	NM_019190.1 Latest version!	Rattus norvegicus CD46 molecule (Cd46), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa35743	XM_006250478.3 Latest version!	Rattus norvegicus CD46 molecule (Cd46), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa43249	XM_008769849.2 Latest version!	Rattus norvegicus CD46 molecule (Cd46), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd46 ( NM_019190.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062063.1 Rattus norvegicus CD46 molecule (Cd46), mRNA.

Price & Availability↑

CloneID	ORa03982
Clone ID Related Accession (Same CDS sequence)	NM_019190.1
Accession Version	NM_019190.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Rattus norvegicus(Norway rat)
Product	membrane cofactor protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB010920.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB010920.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGACAGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGTTGT TGGAGTTATT 
GTAATTTGTC TCATCATACT CAGGTGTTCT GAGTACAGGA AGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062063.1
CDS	12..1079
Translation	MTAAPLTPDPTHPRRRRKSYTFFSLGIYAEALLFLLSSLSDACEPPPPFEAMELKDKPKPHYAIGEIIEYTCKKGYLYLSPYPMTAICQPNHTWVPISDHGCIKVQCTMLQDPSFGKVHYIDGRFSWGARVKYTCMNGYYMVGMSVLQCELNGNGDAFWNGHPPSCKKVYCLPPPKIKNGTHTFTDIKVFKYHEAVIYSCDPNPGPDKFSLVGPSMLFCAGHNTWSSDPPECKVVKCPFPVLQNGRQISRTEKKFSYQALVLFQCLEGFYMEGSSMVVCGAKSSWEPSIPQCLKGPKPHSTKPPVYSESGYPSPREGIFGQEFDAWIIALIVVTSVVGVIVICLIILRCSEYRKK

Target ORF information:

RefSeq Version	NM_019190.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD46 molecule (Cd46), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019190.1

ORF Insert Sequence:

ATGACAGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGTTGT TGGAGTTATT 
GTAATTTGTC TCATCATACT CAGGTGTTCT GAGTACAGGA AGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd46 ( XM_006250478.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250540.1 Rattus norvegicus CD46 molecule (Cd46), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa35743
Clone ID Related Accession (Same CDS sequence)	XM_006250478.3
Accession Version	XM_006250478.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	membrane cofactor protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250478.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGAAAT GTATCTGCAG 
CAAGATGAAA AATCCCACGT GTGGAAGTCA TTACTGTTCC ATTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250540.1
CDS	758..1825
Translation	MTAAPLTPDPTHPRRRRKSYTFFSLGIYAEALLFLLSSLSDACEPPPPFEAMELKDKPKPHYAIGEIIEYTCKKGYLYLSPYPMTAICQPNHTWVPISDHGCIKVQCTMLQDPSFGKVHYIDGRFSWGARVKYTCMNGYYMVGMSVLQCELNGNGDAFWNGHPPSCKKVYCLPPPKIKNGTHTFTDIKVFKYHEAVIYSCDPNPGPDKFSLVGPSMLFCAGHNTWSSDPPECKVVKCPFPVLQNGRQISRTEKKFSYQALVLFQCLEGFYMEGSSMVVCGAKSSWEPSIPQCLKGPKPHSTKPPVYSESGYPSPREGIFGQEFDAWIIALIVVTSEMYLQQDEKSHVWKSLLFHF

Target ORF information:

RefSeq Version	XM_006250478.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD46 molecule (Cd46), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250478.3

ORF Insert Sequence:

ATGACGGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGAAAT GTATCTGCAG 
CAAGATGAAA AATCCCACGT GTGGAAGTCA TTACTGTTCC ATTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd46 ( XM_008769849.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768071.1 Rattus norvegicus CD46 molecule (Cd46), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43249
Clone ID Related Accession (Same CDS sequence)	XM_008769849.2
Accession Version	XM_008769849.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	membrane cofactor protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769849.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGTTGT TGGAGTTATT 
GTAATTTGTC TCATCATACT CAGGTGTTCT GAGTACAGGA AGAAATGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768071.1
CDS	143..1213
Translation	MTAAPLTPDPTHPRRRRKSYTFFSLGIYAEALLFLLSSLSDACEPPPPFEAMELKDKPKPHYAIGEIIEYTCKKGYLYLSPYPMTAICQPNHTWVPISDHGCIKVQCTMLQDPSFGKVHYIDGRFSWGARVKYTCMNGYYMVGMSVLQCELNGNGDAFWNGHPPSCKKVYCLPPPKIKNGTHTFTDIKVFKYHEAVIYSCDPNPGPDKFSLVGPSMLFCAGHNTWSSDPPECKVVKCPFPVLQNGRQISRTEKKFSYQALVLFQCLEGFYMEGSSMVVCGAKSSWEPSIPQCLKGPKPHSTKPPVYSESGYPSPREGIFGQEFDAWIIALIVVTSVVGVIVICLIILRCSEYRKKW

Target ORF information:

RefSeq Version	XM_008769849.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD46 molecule (Cd46), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769849.2

ORF Insert Sequence:

ATGACGGCGG CGCCTCTCAC GCCAGACCCA ACGCATCCCC GTCGCAGAAG GAAGAGCTAC 
ACTTTCTTCT CCCTGGGCAT TTACGCTGAG GCCCTTCTGT TTCTGCTGTC TAGTTTATCT 
GATGCCTGTG AACCACCACC ACCATTTGAA GCTATGGAAC TCAAGGATAA GCCTAAACCC 
CATTATGCGA TTGGAGAGAT AATAGAATAT ACGTGTAAAA AAGGATACCT ATATCTGTCT 
CCATACCCAA TGACTGCTAT CTGTCAGCCA AATCACACAT GGGTCCCTAT TTCAGATCAT 
GGTTGTATTA AAGTTCAATG TACTATGTTA CAGGACCCTT CGTTTGGCAA AGTACACTAC 
ATAGATGGTA GATTTTCATG GGGTGCTCGA GTTAAATATA CTTGTATGAA TGGTTATTAC 
ATGGTTGGTA TGTCAGTTCT ACAGTGTGAG CTTAATGGCA ACGGTGATGC ATTCTGGAAT 
GGCCATCCCC CAAGTTGTAA AAAAGTCTAT TGTTTACCAC CTCCAAAAAT AAAAAATGGA 
ACACACACCT TTACTGATAT AAAAGTATTC AAATACCATG AAGCAGTAAT TTACAGTTGT 
GATCCTAACC CAGGGCCAGA TAAGTTTTCC CTTGTTGGAC CGAGCATGCT ATTCTGTGCT 
GGCCATAACA CCTGGAGTAG CGACCCTCCG GAGTGTAAAG TGGTAAAATG TCCATTTCCA 
GTGCTACAAA ATGGAAGACA GATATCAAGA ACTGAAAAAA AATTTTCCTA CCAAGCACTA 
GTGCTGTTTC AGTGTTTGGA GGGATTTTAC ATGGAGGGCA GTAGCATGGT GGTCTGTGGT 
GCTAAGAGCT CTTGGGAGCC CTCTATCCCA CAATGTCTTA AAGGTCCTAA GCCTCATTCT 
ACCAAGCCTC CAGTTTACAG TGAATCAGGA TATCCTAGTC CCCGTGAAGG AATATTTGGC 
CAAGAATTCG ATGCATGGAT CATTGCTTTG ATTGTTGTTA CTTCAGTTGT TGGAGTTATT 
GTAATTTGTC TCATCATACT CAGGTGTTCT GAGTACAGGA AGAAATGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism.
Thrombosis research135(4)659-65(2015 Apr)
Lewis DA,Suchindran S,Beckman MG,Hooper WC,Grant AM,Heit JA,Manco-Johnson M,Moll S,Philipp CS,Kenney K,De Staercke C,Pyle ME,Chi JT,Ortel TL

Genetic analysis of membrane cofactor protein (CD46) of the complement system in women with and without preeclamptic pregnancies.
PloS one10(2)e0117840(2015)
Lokki AI,Aalto-Viljakainen T,Meri S,Laivuori H,

Use of complement regulators, CD35, CD46, CD55, and CD59, on leukocytes as markers for diagnosis of viral and bacterial infections.
Human immunology74(5)522-30(2013 May)
Nuutila J,Jalava-Karvinen P,Hohenthal U,Kotilainen P,Pelliniemi TT,Nikoskelainen J,Lilius EM

The CD46-Jagged1 interaction is critical for human TH1 immunity.
Nature immunology13(12)1213-21(2012 Dec)
Le Friec G,Sheppard D,Whiteman P,Karsten CM,Shamoun SA,Laing A,Bugeon L,Dallman MJ,Melchionna T,Chillakuri C,Smith RA,Drouet C,Couzi L,Fremeaux-Bacchi V,Köhl J,Waddington SN,McDonnell JM,Baker A,Handford PA,Lea SM,Kemper C

Complement inhibitory proteins expression in placentas of thrombophilic women.
Folia histochemica et cytobiologica50(3)460-7(2012 Oct)
Wirstlein PK,Jasiński P,Rajewski M,Goździewicz T,Skrzypczak J

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Cd46 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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