Ppargc1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ppargc1b
Entrez Gene ID	291567
Full Name	PPARG coactivator 1 beta
Synonyms	PGC1beta,Perc
General protein information	Preferred Names PPARG coactivator 1 beta Names peroxisome proliferator-activated receptor gamma coactivator 1-beta PGC-1-beta PPAR-gamma coactivator 1-beta PPARGC-1-beta peroxisome proliferative activated receptor, gamma, coactivator 1 beta peroxisome proliferator-activated receptor gamma coactivator 1beta-2a
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_176075.2	NP_788264.1	peroxisome proliferator-activated receptor gamma coactivator 1-beta

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PPARGC1B	XP_546308.3
Xenopus tropicalis (tropical clawed frog)	ppargc1b	XP_002936744.2
Bos taurus (cattle)	PPARGC1B	XP_003586376.1
Rattus norvegicus (Norway rat)	Ppargc1b	NP_788264.1
Pan troglodytes (chimpanzee)	PPARGC1B	XP_003310943.1
Macaca mulatta (Rhesus monkey)	LOC711027	XP_002804631.1
Danio rerio (zebrafish)	ppargc1b	XP_003199944.2
Homo sapiens (human)	PPARGC1B	NP_573570.3
Mus musculus (house mouse)	Ppargc1b	NP_573512.1
Gallus gallus (chicken)	PPARGC1B	XP_414479.4

Gene Ontology
Bibliography

Related articles in PubMed

MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα.
Yin Z, Zhao Y, He M, Li H, Fan J, Nie X, Yan M, Chen C, Wang DW
Cardiovascular diabetology18(1)7(2019 01)

PPAR Gamma Coactivator 1 Beta (PGC-1β) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons.
Liu YC, Gao XX, Zhang ZG, Lin ZH, Zou QL
Cellular and molecular neurobiology37(5)879-887(2017 Jul)

Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.
Cho Y, Hazen BC, Russell AP, Kralli A
The Journal of biological chemistry288(35)25207-18(2013 Aug)

Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.
Guo Y, Fan Y, Zhang J, Chang L, Lin JD, Chen YE
The Journal of biological chemistry288(7)4625-36(2013 Feb)

PGC-1β modulates the expression of genes involved in mitochondrial function and adipogenesis during preadipocyte differentiation.
Ji H, Lu RH, Chang ZG, Su SS, Yang GS
Reproduction in domestic animals = Zuchthygiene47(3)419-27(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ppargc1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppargc1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03985	NM_176075.2 Latest version!	Rattus norvegicus PPARG coactivator 1 beta (Ppargc1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ppargc1b ( NM_176075.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_788264.1 Rattus norvegicus PPARG coactivator 1 beta (Ppargc1b), mRNA.

Price & Availability↑

CloneID	ORa03985
Clone ID Related Accession (Same CDS sequence)	NM_176075.2
Accession Version	NM_176075.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2973bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556640000000
Organism	Rattus norvegicus(Norway rat)
Product	peroxisome proliferator-activated receptor gamma coactivator 1-beta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY188951.1. On Jun 3, 2003 this sequence version replaced NM_176075.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY188951.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCAGGGGG AAGGGAAGGG TGGGGAGTCT GGAGAGGAAC AGTTATGTGC TGACTTGCCA 
GAGCTCGACC TCTCCCAGCT GGATGCCAGT GACTTCGACT CAGCCACGTG CTTTGGGGAG 
CTGCAGTGGT GCCCGGAGAC CTCAGAGACA GAGCCCAGCC AGTACAGCCC TGATGATTCC 
GAGTTCTTCC AGATTGACAG TGAGAATGAA GCTCTCTTGG CTGCGCTTAC CAAGACCCTG 
GATGACATCC CCGAAGACGA TGTGGGGCTG GCTGCCTTCC CAGGACTGGA TGAAGGCGAC 
ACACCCTCCT GCACCCCAGC TTCACCTGCT CCTTTATCTG TGCCCCCCAG CCCCGCCTTG 
GAGAGGCTTC TGTCCCCAGT GTCTGAAGTG GATGAGCTTT CACTGCTGCA GAAGCTCCTC 
CTGGCCACAT CCTCCCCAAC AGCAAGCTCT GATGCTCTGA AGGACGGGGC CACCTGGTCG 
CAGACCAGCC TCAGTTCCAG AAGTCAGCGG CCTTGTGTCA AGGTGGATGG CACCCAGGAC 
AAGAAGACCC CCATGCTACG GTCTCAGAGC CGGCCTTGTA CAGAACTGCA TAAGCACCTC 
ACTTCGGTGC TGCCCTGCCC CAGGGGAAAA GCCTGTTCCC CACCTCCCCA CCCAAGTCCT 
CAGCTCCTCT CCAAAGAGGA TGAGGAGGTG GGAGAGGATT GCCCAAGCCC CTGGCCAGCT 
CCAGCGTCTC CCCAAGACTC ACTAGGACAG GACACGGCCA ACCCCAACAG TGCCCAAGTT 
CCCAAGGACG ACGTGAGGGC CATGGTACAG CTCATTCGCT ACATGCATAC CTACTGCCTG 
CCTCAGAGGA AGCTGCCCCA ACGGGCCTCA GAGCCAATCC CCCAGTCCTG CAGCAGCCCC 
TTGAGGAAGG TCCCACCCCG ATCCCGGCAA ACCCCCAAAG CCTTCTGGAC TGAGTTCTCC 
ATCCTAAGGG AACTTCTGGC CCAAGATATC CTCTGTGATG TTAGCAAGCC CTACCGCCTG 
GCCACACCTG TCTATGCTTC TCTCACACCC CAGTCCAGAA CCAGGCCCCC CAAAGACAGT 
CAGGCCTCCC CTGCCCACTC TGCCATGGCA GAAGAGGTGA GAATCACTGC TTCCCCCAAG 
AGCACTGGAC CTAGACCCAG CCTCCGTCCT CTGAGGCTAG AGGTGAAACG GGATGTCAAC 
AAGCCTGCAA GGCAAAAGCG GGAGGAAGAT GAGGAGGAGG AAGAGGAAGA AGAAGAGGAA 
GAAGAAAAAG AGGATGAAGA AGAGGAGTGG GGCAGGAAGA GACCAGGTCG TGGCCTGCCA 
TGGACCAAAC TAGGGAGGAA GATGGACAGC TCTGTGTGCC CTGTGCGGCG CTCCAGGAGA 
CTGAATCCAG AGCTGGGCCC TTGGCTGACA TTCACTGATG AGCCCCTAGG TGCTCTACCC 
TCGATGTGCC TGGCTACAGA GACCCACGAC CTGGAAGAAG AGCTGGGCGG CCTCACAGAC 
AGTAGTCAAG GCCAGCAGCT CCCCCTGGGA TCCCAGATCC CCACCCTGGA AAGCCCCTGT 
GAAAGTGGGT GTGGGGACAC AGATGAAGAT CCAAGCTGCC CGCGGCCCCC TTCCAGAGAC 
TCCCCCAGGT GCCTCATGCT GGCCTTGTCA CAAAGTGACC CTCTTGGCAA GAAGAGCTTT 
GAGGAGTCCT TGACAGTGGA GCTTTGTGGC ACAGCAGGAC TCACTCCACC CACCACACCT 
CCATATAAGC CCATGGAGGA GGACCCCTTC AAGCAGGACA CCAAGCACAG CCCAGGCCAA 
GACACAGCTC CCAGCCTCCC TTCCCCTGAG ACTCTTCAGC TCACAGCCAC CCCAGGGGCT 
TCCCACAAGC TGCCCAAGAG GCACCCGGAG CGAAGTGAGC TCCTGTCTCA TCTGCAACAT 
GCCACAACCC AGCCAGTCTC ACAGGCTGGC CAGAAGCGTC CCTTCTCCTG CTCCTTTGGA 
GACCATGACT ACTGCCAGGT GATCAGGCCA GAGGCTGCCC TGCAGAGGAA GGTGCTGCGG 
TCCTGGGAGC CAATCAAGGT CCACCTTGAA GACTTGGCCC ACCAGGGTGC AACCCTGCCA 
GTGGAAACAA AGACCCCTAG GAGGGAGGCA GACCAGAACT GTGACCCCAC CCCCAAGGAC 
AGCATGCAGC TAAGAGACCA TGAGATCCGT GCCAGCCTCA CAAAGCACTT TGGGCTGCTG 
GAAACCGCTC TGGAGGAGGA AGACTTGGCT TCATGTAAAA GCCCGGAGTA TGACACCGTA 
TTTGAGGACA GCAGCAGCAG CAGTGGCGAG AGCAGCTTCC TGCTAGAGGA GGAGGAAGAG 
GAGGGAGGGG AAGAGGACGA TGAAGGAGAG GACTCAGGGG TCAGCCCTCC CTGCTCCGAC 
CACTGCCCCT ACCAGAGCCC ACCCAGTAAG GCCAGTCGGC AGCTCTGTTC CCGAAGCCGC 
TCCAGTTCTG GCTCCTCATC CTGTAGCTCC TGGTCACCAG CTACCCGGAA GAACTTCAGA 
CTTGAGAGCA GAGGGCCCTG TTCAGATGGA ACCCCAAGCG CCCGGCATGC CAAGAAGCGG 
CGGGAAAAGG CCATCGGTGA AGGTCGTGTG GTATACATCC GAAATCTCTC CGGTGACATG 
AGCTCTCGAG AACTAAAGAA GCGCTTCGAG GTGTTTGGTG AGATAGTCGA GTGCCAGGTG 
CTGAGGAGAA GTAAGAGAGG CCAGAAGCAC GGTTTTATTA CCTTCCGGTG TTCGGAGCAT 
GCCGCCCTGT CCGTGAGGAA CGGCGCTACC CTGAGAAAAC GCAATGAGCC CTCCTTCCAC 
CTGAGCTATG GAGGGCTCCG GCACTTCCGC TGGCCCAGAT ACACCGACTA TGATCCCACG 
TCTGAAGAGT CCCTTCCCTC GTCTGGGAAA AGCAAGTACG AAGCCATGGA TTTTGACAGC 
TTACTGAAAG AGGCCCAGCA GAGCCTGCAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_788264.1
CDS	1..2973
Translation	MQGEGKGGESGEEQLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSEFFQIDSENEALLAALTKTLDDIPEDDVGLAAFPGLDEGDTPSCTPASPAPLSVPPSPALERLLSPVSEVDELSLLQKLLLATSSPTASSDALKDGATWSQTSLSSRSQRPCVKVDGTQDKKTPMLRSQSRPCTELHKHLTSVLPCPRGKACSPPPHPSPQLLSKEDEEVGEDCPSPWPAPASPQDSLGQDTANPNSAQVPKDDVRAMVQLIRYMHTYCLPQRKLPQRASEPIPQSCSSPLRKVPPRSRQTPKAFWTEFSILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVNKPARQKREEDEEEEEEEEEEEEKEDEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPELGPWLTFTDEPLGALPSMCLATETHDLEEELGGLTDSSQGQQLPLGSQIPTLESPCESGCGDTDEDPSCPRPPSRDSPRCLMLALSQSDPLGKKSFEESLTVELCGTAGLTPPTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETLQLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAGQKRPFSCSFGDHDYCQVIRPEAALQRKVLRSWEPIKVHLEDLAHQGATLPVETKTPRREADQNCDPTPKDSMQLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLLEEEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRLESRGPCSDGTPSARHAKKRREKAIGEGRVVYIRNLSGDMSSRELKKRFEVFGEIVECQVLRRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLPSSGKSKYEAMDFDSLLKEAQQSLH

Target ORF information:

RefSeq Version	NM_176075.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PPARG coactivator 1 beta (Ppargc1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176075.2

ORF Insert Sequence:

ATGCAGGGGG AAGGGAAGGG TGGGGAGTCT GGAGAGGAAC AGTTATGTGC TGACTTGCCA 
GAGCTCGACC TCTCCCAGCT GGATGCCAGT GACTTCGACT CAGCCACGTG CTTTGGGGAG 
CTGCAGTGGT GCCCGGAGAC CTCAGAGACA GAGCCCAGCC AGTACAGCCC TGATGATTCC 
GAGTTCTTCC AGATTGACAG TGAGAATGAA GCTCTCTTGG CTGCGCTTAC CAAGACCCTG 
GATGACATCC CCGAAGACGA TGTGGGGCTG GCTGCCTTCC CAGGACTGGA TGAAGGCGAC 
ACACCCTCCT GCACCCCAGC TTCACCTGCT CCTTTATCTG TGCCCCCCAG CCCCGCCTTG 
GAGAGGCTTC TGTCCCCAGT GTCTGAAGTG GATGAGCTTT CACTGCTGCA GAAGCTCCTC 
CTGGCCACAT CCTCCCCAAC AGCAAGCTCT GATGCTCTGA AGGACGGGGC CACCTGGTCG 
CAGACCAGCC TCAGTTCCAG AAGTCAGCGG CCTTGTGTCA AGGTGGATGG CACCCAGGAC 
AAGAAGACCC CCATGCTACG GTCTCAGAGC CGGCCTTGTA CAGAACTGCA TAAGCACCTC 
ACTTCGGTGC TGCCCTGCCC CAGGGGAAAA GCCTGTTCCC CACCTCCCCA CCCAAGTCCT 
CAGCTCCTCT CCAAAGAGGA TGAGGAGGTG GGAGAGGATT GCCCAAGCCC CTGGCCAGCT 
CCAGCGTCTC CCCAAGACTC ACTAGGACAG GACACGGCCA ACCCCAACAG TGCCCAAGTT 
CCCAAGGACG ACGTGAGGGC CATGGTACAG CTCATTCGCT ACATGCATAC CTACTGCCTG 
CCTCAGAGGA AGCTGCCCCA ACGGGCCTCA GAGCCAATCC CCCAGTCCTG CAGCAGCCCC 
TTGAGGAAGG TCCCACCCCG ATCCCGGCAA ACCCCCAAAG CCTTCTGGAC TGAGTTCTCC 
ATCCTAAGGG AACTTCTGGC CCAAGATATC CTCTGTGATG TTAGCAAGCC CTACCGCCTG 
GCCACACCTG TCTATGCTTC TCTCACACCC CAGTCCAGAA CCAGGCCCCC CAAAGACAGT 
CAGGCCTCCC CTGCCCACTC TGCCATGGCA GAAGAGGTGA GAATCACTGC TTCCCCCAAG 
AGCACTGGAC CTAGACCCAG CCTCCGTCCT CTGAGGCTAG AGGTGAAACG GGATGTCAAC 
AAGCCTGCAA GGCAAAAGCG GGAGGAAGAT GAGGAGGAGG AAGAGGAAGA AGAAGAGGAA 
GAAGAAAAAG AGGATGAAGA AGAGGAGTGG GGCAGGAAGA GACCAGGTCG TGGCCTGCCA 
TGGACCAAAC TAGGGAGGAA GATGGACAGC TCTGTGTGCC CTGTGCGGCG CTCCAGGAGA 
CTGAATCCAG AGCTGGGCCC TTGGCTGACA TTCACTGATG AGCCCCTAGG TGCTCTACCC 
TCGATGTGCC TGGCTACAGA GACCCACGAC CTGGAAGAAG AGCTGGGCGG CCTCACAGAC 
AGTAGTCAAG GCCAGCAGCT CCCCCTGGGA TCCCAGATCC CCACCCTGGA AAGCCCCTGT 
GAAAGTGGGT GTGGGGACAC AGATGAAGAT CCAAGCTGCC CGCGGCCCCC TTCCAGAGAC 
TCCCCCAGGT GCCTCATGCT GGCCTTGTCA CAAAGTGACC CTCTTGGCAA GAAGAGCTTT 
GAGGAGTCCT TGACAGTGGA GCTTTGTGGC ACAGCAGGAC TCACTCCACC CACCACACCT 
CCATATAAGC CCATGGAGGA GGACCCCTTC AAGCAGGACA CCAAGCACAG CCCAGGCCAA 
GACACAGCTC CCAGCCTCCC TTCCCCTGAG ACTCTTCAGC TCACAGCCAC CCCAGGGGCT 
TCCCACAAGC TGCCCAAGAG GCACCCGGAG CGAAGTGAGC TCCTGTCTCA TCTGCAACAT 
GCCACAACCC AGCCAGTCTC ACAGGCTGGC CAGAAGCGTC CCTTCTCCTG CTCCTTTGGA 
GACCATGACT ACTGCCAGGT GATCAGGCCA GAGGCTGCCC TGCAGAGGAA GGTGCTGCGG 
TCCTGGGAGC CAATCAAGGT CCACCTTGAA GACTTGGCCC ACCAGGGTGC AACCCTGCCA 
GTGGAAACAA AGACCCCTAG GAGGGAGGCA GACCAGAACT GTGACCCCAC CCCCAAGGAC 
AGCATGCAGC TAAGAGACCA TGAGATCCGT GCCAGCCTCA CAAAGCACTT TGGGCTGCTG 
GAAACCGCTC TGGAGGAGGA AGACTTGGCT TCATGTAAAA GCCCGGAGTA TGACACCGTA 
TTTGAGGACA GCAGCAGCAG CAGTGGCGAG AGCAGCTTCC TGCTAGAGGA GGAGGAAGAG 
GAGGGAGGGG AAGAGGACGA TGAAGGAGAG GACTCAGGGG TCAGCCCTCC CTGCTCCGAC 
CACTGCCCCT ACCAGAGCCC ACCCAGTAAG GCCAGTCGGC AGCTCTGTTC CCGAAGCCGC 
TCCAGTTCTG GCTCCTCATC CTGTAGCTCC TGGTCACCAG CTACCCGGAA GAACTTCAGA 
CTTGAGAGCA GAGGGCCCTG TTCAGATGGA ACCCCAAGCG CCCGGCATGC CAAGAAGCGG 
CGGGAAAAGG CCATCGGTGA AGGTCGTGTG GTATACATCC GAAATCTCTC CGGTGACATG 
AGCTCTCGAG AACTAAAGAA GCGCTTCGAG GTGTTTGGTG AGATAGTCGA GTGCCAGGTG 
CTGAGGAGAA GTAAGAGAGG CCAGAAGCAC GGTTTTATTA CCTTCCGGTG TTCGGAGCAT 
GCCGCCCTGT CCGTGAGGAA CGGCGCTACC CTGAGAAAAC GCAATGAGCC CTCCTTCCAC 
CTGAGCTATG GAGGGCTCCG GCACTTCCGC TGGCCCAGAT ACACCGACTA TGATCCCACG 
TCTGAAGAGT CCCTTCCCTC GTCTGGGAAA AGCAAGTACG AAGCCATGGA TTTTGACAGC 
TTACTGAAAG AGGCCCAGCA GAGCCTGCAT TAA