Ints7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ints7
Entrez Gene ID	289382
Full Name	integrator complex subunit 7
Synonyms	RGD1308014
General protein information	Preferred Names integrator complex subunit 7 Names integrator complex subunit 7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q27

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191675.1	NP_001178604.1	integrator complex subunit 7

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011393	XP_317927.4
Macaca mulatta (Rhesus monkey)	INTS7	XP_001108251.1
Rattus norvegicus (Norway rat)	Ints7	NP_001178604.1
Gallus gallus (chicken)	INTS7	NP_001006399.1
Mus musculus (house mouse)	Ints7	NP_848747.4
Drosophila melanogaster (fruit fly)	defl	NP_648352.2
Bos taurus (cattle)	INTS7	NP_001069512.1
Homo sapiens (human)	INTS7	NP_056249.1
Pan troglodytes (chimpanzee)	INTS7	XP_514179.4
Canis lupus familiaris (dog)	INTS7	XP_857568.2
Danio rerio (zebrafish)	ints7	NP_775374.1
Xenopus tropicalis (tropical clawed frog)	ints7	XP_002934743.1

Gene Ontology
Bibliography

Related articles in PubMed

Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.
Jodoin JN, Sitaram P, Albrecht TR, May SB, Shboul M, Lee E, Reversade B, Wagner EJ, Lee LA
Molecular biology of the cell24(18)2954-65(2013 Sep)

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.
Cotta-Ramusino C, McDonald ER 3rd, Hurov K, Sowa ME, Harper JW, Elledge SJ
Science (New York, N.Y.)332(6035)1313-7(2011 Jun)

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R
Cell123(2)265-76(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ints7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ints7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07373	NM_001191675.1 Latest version!	Rattus norvegicus integrator complex subunit 7 (Ints7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ints7 ( NM_001191675.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178604.1 Rattus norvegicus integrator complex subunit 7 (Ints7), mRNA.

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CloneID	ORa07373
Clone ID Related Accession (Same CDS sequence)	NM_001191675.1
Accession Version	NM_001191675.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2904bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527696000000
Organism	Rattus norvegicus(Norway rat)
Product	integrator complex subunit 7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07022157.1. On Jul 17, 2010 this sequence version replaced XM_223075.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCAA ACTCAACCAA GTCTTTCCTG GCCGATGCCG GCTATGGCGA ACAGGAGCTG 
GACGCTAACT CCGCTCTTAT GGAACTGGAC AAAGGTCTGA GGTCTGGCAA ACTCGGGGAG 
CAGTGTGAAG CGGTCGTGCG CTTTCCCAGG CTTTTCCAGA AGTACCCGTT CCCTATTCTC 
ATCAATTCAG CGTTCCTAAA GTTAGCTGAC GTTTTCAGAG TTGGAAACAA CTTCCTGCGG 
CTGTGTGTTC TCAAAGTGAC CCAGCAAAGT GAAAAGCACC TGGAGAAGAT TCTAAACGTG 
GATGAATTTG TGAAGAGGGT TTTCTCGGTG ATTCACAGTA ATGACCCTGT GGCGAGAGCC 
ATCACCCTAC GGATGTTGGG AAGTCTGGCG TCAATCATCC CTGAGAGGAA GAATGCCCAC 
CACAGCATCC GTCAGAGTCT GGACTCCCAT GACAATGTAG AAGTTGAAGC TGCTGTCTTT 
GCAGCCGCAA ACTTCTCGGC ACAGTCAAAG GATTTTGCTG TGGGGATCTG TAACAAAATC 
AGCGAAATGA TTCAAGGCTT AGCTACACCA GTGGACCTGA AGCTGAAACT GATCCCCATC 
CTGCAGCACA TGCACCATGA TGCCATCTTG GCCTCCAGTG CCCGCCAGCT CCTGCAGCAG 
CTGGTCACCT CATACCCCTC CACCAAAATG GTCATCGTGT CTCTACACAC TTTCACTCTG 
CTCGCAGCCT CCTCTTTGGT TGACACACCC AAGCAGATTC AACTTCTGCT GCAGTATTTG 
AAGAGCGACC CCAGGAAAGC TGTGAAGAGA CTTGCTGTTC AGGATCTGAA GCTGCTCGCT 
AGTAAGACAC CACACACGTG GAGTAAAGAG AACATTCAGG CACTCTGTGA GTGTGCACTG 
CATACTCCTT ATGACAGCTT GAAGCTAGGG ATGTTGTCTG TCCTCTCCAC ACTGTCAGGG 
ACCATCGCCA TTAAACATTA CTTCAGTGTG GCTCCAGGAA ATGTAGGCTC GTCCCCCAGA 
TCTTCTGATT TAGTCAAATT AGCCCAAGAA TGCTGTTACC ATAGCAACAG GGCCATTGCA 
GCACATGGAG TGAGAGTGCT GACTAATATA ACTGTGTCTT GTCAAGAAAA AGATCTCTTG 
TCTCTGGAGC AAGATGCTGT CTTTGGCCTG GAATCCCTTC TGGTGCTTTG TAGTCAAGAT 
GACAGTCCAG GTGCTCAGTC CACTGTGAAG AGTGCTCTCA GCTGTATGGT GAAGCTGGCC 
AAGGGCCGCC CACATTTGAG CCGGTCAGTG GTTGACACTC TGCTAACTCA GCTGCACAGC 
TCTCAGGATG CTGCCCGGAT CCTCATGTGC CACTGCCTGG CAGCCATTGC CATGAAGCTC 
CCAGTACTGG GTGATGGAAT GCTTGGTGAC CTCGTGGAGC TCTACAAGGT GATTGGACGA 
TCAGCCACAG ACAAGCAACA GGAGCTTCTG GTAAGTTTGG CTACTGTGAT TTTCGTAGCC 
AGCCAGAAAG CATTGTCTGC GGAAGTAAAG GCAGTAATCA AGCAGCAACT TGAAAGCGTC 
TCCAGTGGGT GGACCGTATA CCGGATTGCC AGGCAGGCTT CCAGAATGGG CAACCATGAC 
ATGGCCCGAG AGCTCTACCA GAGTTTGCTG ACGCAGGTCG CATCAGAGCA CTTCTACTTC 
TGGCTGAACA GTCTGAAGGA GTTCTCACAC GCAGAGCAGT GTCTGACTGG GCTGCAGGAG 
GGTAGCTTCA GCTCAGCACT TTCCTGCATT GCTGAGTCTT TGAAATTCTA CCACAAAGGG 
ATCGCCTCCT TAACAGCTGC CAGCACGCCA CTGAATCCTT TAAGCTTTCA GTGTGAGTTT 
GTGAAACTCA GGATCGATCT TCTCCAAGCC TTCTCGCAAC TTATTTGTAC TTGTAACAGC 
CTGAAGACAA GCCCTCCCCC TGCGATCGCC ACGACGATTG CCATGACCTT AGGGAATGAT 
CTTCAGAGGT GTGGCCGGAT CTCCAATCAG ATGAAGCAGT CCATGGAAGA GTTCCGAAGC 
CTTGCCTCCC GGTACCGGGA TCTCTATCAG GCGTCCTTCG ATGCAGACTC GGCAACTCTG 
AGGAACGTAG AACTCCAGCA GCAGAGCTGC TTACTGATAG CCCACGCTAT AGAAGCCCTG 
GTTTTGGATC CTGAATCAGC AAGTTTCCAG GAGTATGGGT CCACAGGCGC TGCCCACGCG 
GACAGCGAGT ATGAGAGAAG GATGATGTCC GTGTACAGCC ACGTCCTAGA GGAGGTGGAG 
TCGCTTAACC GGAAGTACGC CCCAGTTTCC TACATGCACA CAGCATGCCT CTGCAATGCC 
ATCATCGCTT TGCTGAAAGT TCCTCTCTCA TTTCAGAGAT ACTTTTTCCA GAAACTGCAG 
TCTACCAGCA TCAAGCTTGC TCTGTCACCC TCTCCCCGGA ACCCTGCAGA GCCCATTGCT 
GTACAGAATA ACCAGCAGCT GGCATTAAAG GTAGAAGGCG TTGTTCAGCA CGGGTCTAAA 
CCAGGACTGT TCCGCAGAAT CCAATCTGTG TGTCTGAATG TTTCTTCTAC ACTCCAGAGT 
AAATCCAGCC AGGACTACAA GATTCCCGTT GACAGCATGA CCAATGAGAT GGAGCAGAGG 
GTCGAGCCAC ATAATGATTA CTTCAGCACT CAGTTTCTGT TGAACTTCGC TGTCCTTGGA 
ACGCACAGCA TTACAGTGGA GTCATCAGTG AGAGATGCCA ATGGCATCGT CTGGAAGACG 
GGTCCCAGAA CTACCATGTT TGTCAAATCC CTGGAAGACC CCTATTCCCA GCAGATTCGC 
CTACAGCAGC AGCAAGCCCA GCAGCCTTTG CAGCCACAGC CGCAGCCGCA GCCGCAGCCT 
CGCGGTGCCT ACACCCGGTT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178604.1
CDS	64..2967
Translation	MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKSDPRKAVKRLAVQDLKLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVAPGNVGSSPRSSDLVKLAQECCYHSNRAIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLESLLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSSQDAARILMCHCLAAIAMKLPVLGDGMLGDLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEGSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHADSEYERRMMSVYSHVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRRIQSVCLNVSSTLQSKSSQDYKIPVDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQQIRLQQQQAQQPLQPQPQPQPQPRGAYTRF

Target ORF information:

RefSeq Version	NM_001191675.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrator complex subunit 7 (Ints7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191675.1

ORF Insert Sequence:

ATGGCGTCAA ACTCAACCAA GTCTTTCCTG GCCGATGCCG GCTATGGCGA ACAGGAGCTG 
GACGCTAACT CCGCTCTTAT GGAACTGGAC AAAGGTCTGA GGTCTGGCAA ACTCGGGGAG 
CAGTGTGAAG CGGTCGTGCG CTTTCCCAGG CTTTTCCAGA AGTACCCGTT CCCTATTCTC 
ATCAATTCAG CGTTCCTAAA GTTAGCTGAC GTTTTCAGAG TTGGAAACAA CTTCCTGCGG 
CTGTGTGTTC TCAAAGTGAC CCAGCAAAGT GAAAAGCACC TGGAGAAGAT TCTAAACGTG 
GATGAATTTG TGAAGAGGGT TTTCTCGGTG ATTCACAGTA ATGACCCTGT GGCGAGAGCC 
ATCACCCTAC GGATGTTGGG AAGTCTGGCG TCAATCATCC CTGAGAGGAA GAATGCCCAC 
CACAGCATCC GTCAGAGTCT GGACTCCCAT GACAATGTAG AAGTTGAAGC TGCTGTCTTT 
GCAGCCGCAA ACTTCTCGGC ACAGTCAAAG GATTTTGCTG TGGGGATCTG TAACAAAATC 
AGCGAAATGA TTCAAGGCTT AGCTACACCA GTGGACCTGA AGCTGAAACT GATCCCCATC 
CTGCAGCACA TGCACCATGA TGCCATCTTG GCCTCCAGTG CCCGCCAGCT CCTGCAGCAG 
CTGGTCACCT CATACCCCTC CACCAAAATG GTCATCGTGT CTCTACACAC TTTCACTCTG 
CTCGCAGCCT CCTCTTTGGT TGACACACCC AAGCAGATTC AACTTCTGCT GCAGTATTTG 
AAGAGCGACC CCAGGAAAGC TGTGAAGAGA CTTGCTGTTC AGGATCTGAA GCTGCTCGCT 
AGTAAGACAC CACACACGTG GAGTAAAGAG AACATTCAGG CACTCTGTGA GTGTGCACTG 
CATACTCCTT ATGACAGCTT GAAGCTAGGG ATGTTGTCTG TCCTCTCCAC ACTGTCAGGG 
ACCATCGCCA TTAAACATTA CTTCAGTGTG GCTCCAGGAA ATGTAGGCTC GTCCCCCAGA 
TCTTCTGATT TAGTCAAATT AGCCCAAGAA TGCTGTTACC ATAGCAACAG GGCCATTGCA 
GCACATGGAG TGAGAGTGCT GACTAATATA ACTGTGTCTT GTCAAGAAAA AGATCTCTTG 
TCTCTGGAGC AAGATGCTGT CTTTGGCCTG GAATCCCTTC TGGTGCTTTG TAGTCAAGAT 
GACAGTCCAG GTGCTCAGTC CACTGTGAAG AGTGCTCTCA GCTGTATGGT GAAGCTGGCC 
AAGGGCCGCC CACATTTGAG CCGGTCAGTG GTTGACACTC TGCTAACTCA GCTGCACAGC 
TCTCAGGATG CTGCCCGGAT CCTCATGTGC CACTGCCTGG CAGCCATTGC CATGAAGCTC 
CCAGTACTGG GTGATGGAAT GCTTGGTGAC CTCGTGGAGC TCTACAAGGT GATTGGACGA 
TCAGCCACAG ACAAGCAACA GGAGCTTCTG GTAAGTTTGG CTACTGTGAT TTTCGTAGCC 
AGCCAGAAAG CATTGTCTGC GGAAGTAAAG GCAGTAATCA AGCAGCAACT TGAAAGCGTC 
TCCAGTGGGT GGACCGTATA CCGGATTGCC AGGCAGGCTT CCAGAATGGG CAACCATGAC 
ATGGCCCGAG AGCTCTACCA GAGTTTGCTG ACGCAGGTCG CATCAGAGCA CTTCTACTTC 
TGGCTGAACA GTCTGAAGGA GTTCTCACAC GCAGAGCAGT GTCTGACTGG GCTGCAGGAG 
GGTAGCTTCA GCTCAGCACT TTCCTGCATT GCTGAGTCTT TGAAATTCTA CCACAAAGGG 
ATCGCCTCCT TAACAGCTGC CAGCACGCCA CTGAATCCTT TAAGCTTTCA GTGTGAGTTT 
GTGAAACTCA GGATCGATCT TCTCCAAGCC TTCTCGCAAC TTATTTGTAC TTGTAACAGC 
CTGAAGACAA GCCCTCCCCC TGCGATCGCC ACGACGATTG CCATGACCTT AGGGAATGAT 
CTTCAGAGGT GTGGCCGGAT CTCCAATCAG ATGAAGCAGT CCATGGAAGA GTTCCGAAGC 
CTTGCCTCCC GGTACCGGGA TCTCTATCAG GCGTCCTTCG ATGCAGACTC GGCAACTCTG 
AGGAACGTAG AACTCCAGCA GCAGAGCTGC TTACTGATAG CCCACGCTAT AGAAGCCCTG 
GTTTTGGATC CTGAATCAGC AAGTTTCCAG GAGTATGGGT CCACAGGCGC TGCCCACGCG 
GACAGCGAGT ATGAGAGAAG GATGATGTCC GTGTACAGCC ACGTCCTAGA GGAGGTGGAG 
TCGCTTAACC GGAAGTACGC CCCAGTTTCC TACATGCACA CAGCATGCCT CTGCAATGCC 
ATCATCGCTT TGCTGAAAGT TCCTCTCTCA TTTCAGAGAT ACTTTTTCCA GAAACTGCAG 
TCTACCAGCA TCAAGCTTGC TCTGTCACCC TCTCCCCGGA ACCCTGCAGA GCCCATTGCT 
GTACAGAATA ACCAGCAGCT GGCATTAAAG GTAGAAGGCG TTGTTCAGCA CGGGTCTAAA 
CCAGGACTGT TCCGCAGAAT CCAATCTGTG TGTCTGAATG TTTCTTCTAC ACTCCAGAGT 
AAATCCAGCC AGGACTACAA GATTCCCGTT GACAGCATGA CCAATGAGAT GGAGCAGAGG 
GTCGAGCCAC ATAATGATTA CTTCAGCACT CAGTTTCTGT TGAACTTCGC TGTCCTTGGA 
ACGCACAGCA TTACAGTGGA GTCATCAGTG AGAGATGCCA ATGGCATCGT CTGGAAGACG 
GGTCCCAGAA CTACCATGTT TGTCAAATCC CTGGAAGACC CCTATTCCCA GCAGATTCGC 
CTACAGCAGC AGCAAGCCCA GCAGCCTTTG CAGCCACAGC CGCAGCCGCA GCCGCAGCCT 
CGCGGTGCCT ACACCCGGTT TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.
Molecular biology of the cell24(18)2954-65(2013 Sep)
Jodoin JN,Sitaram P,Albrecht TR,May SB,Shboul M,Lee E,Reversade B,Wagner EJ,Lee LA

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.
Science (New York, N.Y.)332(6035)1313-7(2011 Jun)
Cotta-Ramusino C,McDonald ER 3rd,Hurov K,Sowa ME,Harper JW,Elledge SJ

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Cell123(2)265-76(2005 Oct)
Baillat D,Hakimi MA,Näär AM,Shilatifard A,Cooch N,Shiekhattar R

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Ints7 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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