| Gene Symbol | Actl6b |
| Entrez Gene ID | 288563 |
| Full Name | actin-like 6B |
| Synonyms | Actl6 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Actl6b cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Actl6b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Actl6b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa11669 Clone ID Related Accession (Same CDS sequence) NM_001105917.1 Accession Version NM_001105917.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1281bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577203200000 Organism Rattus norvegicus(Norway rat) Product actin-like protein 6B Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473973.1. On or before Oct 3, 2007 this sequence version replaced XM_213739.4, XM_001069085.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261ATGAGCGGGG GCGTCTACGG CGGAGATGAG GTGGGGGCGC TCGTCTTTGA CATTGGCTCC
TTCTCAGTCC GAGCTGGGTA CGCTGGGGAG GACTGCCCCA AGGCTGACTT CCCCACCACT
GTGGGGCTGC TGGCCGCAGA AGAGGGGGGC GGGCTGGAGC TGGAGGGGGA GAAAGAGAAG
AAAGGGAAGA TTTTCCACAT CGACACCAAT GCCCTGCACG TGCCTCGGGA TGGAGCAGAG
GTCATGTCGC CCCTCAAGAA CGGCATGATT GAGGACTGGG AGTGCTTCCG AGCCATCCTG
GATCATACCT ACAGCAAACA TGTCAAGTCC GAACCAAACC TGCACCCAGT ACTCATGTCG
GAGGCTCCGT GGAACACTCG GGCCAAGCGG GAGAAGCTGA CAGAGCTGAT GTTCGAGCAG
TACAACATTC CTGCCTTCTT CTTATGCAAG ACGGCCGTGC TCACAGCCTT TGCAAATGGA
CGCTCCACAG GCCTGGTGCT AGACAGCGGG GCCACCCACA CTACAGCCAT CCCAGTCCAT
GATGGCTATG TCCTACAGCA AGGCATCGTC AAGTCACCCC TGGCTGGCGA CTTCATATCC
ATGCAGTGCC GGGAGCTCTT CCAGGAAATG GCTATTGATA TCATCCCTCC TTACATGATT
GCTGCCAAGG AGCCTGTACG GGAGGGAGCC CCCCCAAACT GGAAGAAGAA GGAGAAGCTA
CCCCAAGTCT CCAAGTCCTG GCATAACTAC ATGTGTAACG AGGTGATCCA AGACTTCCAG
GCCTCTGTAC TGCAGGTGTC TGATTCCCCT TACGATGAAC AGGTAGCTGC ACAAATGCCC
ACAGTGCATT ATGAAATGCC CAATGGCTAC AACACAGACT ATGGTGCTGA GAGACTTCGC
ATCCCTGAGG GCCTGTTTGA TCCCTCTAAT GTCAAGGGTC TGTCTGGGAA CACCATGCTA
GGAGTGGGTC ACGTGGTCAC CACCAGCATC GGCATGTGTG ACATCGACAT TCGCCCGGGT
CTCTATGGCA GTGTCATTGT CACTGGCGGC AACACTCTGC TTCAGGGGTT CACAGACAGA
CTTAATCGGG AGCTTTCCCA GAAGACCCCA CCGAGCATGC GGCTCAAGCT TATCGCCAGC
AACAGCACCA TGGAACGCAA GTTCAGCCCC TGGATTGGGG GCTCCATCTT GGCCTCACTG
GGCACGTTCC AGCAGATGTG GATCTCCAAG CAGGAATATG AGGAGGGAGG GAAGCAGTGT
GTGGAGCGGA AGTGCCCCTG AThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001099387.2 CDS 81..1361 Translation 
Target ORF information:
RefSeq Version NM_001105917.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus actin-like 6B (Actl6b), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001105917.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261ATGAGCGGGG GCGTCTACGG CGGAGATGAG GTGGGGGCGC TCGTCTTTGA CATTGGCTCC
TTCTCAGTCC GAGCTGGGTA CGCTGGGGAG GACTGCCCCA AGGCTGACTT CCCCACCACT
GTGGGGCTGC TGGCCGCAGA AGAGGGGGGC GGGCTGGAGC TGGAGGGGGA GAAAGAGAAG
AAAGGGAAGA TTTTCCACAT CGACACCAAT GCCCTGCACG TGCCTCGGGA TGGAGCAGAG
GTCATGTCGC CCCTCAAGAA CGGCATGATT GAGGACTGGG AGTGCTTCCG AGCCATCCTG
GATCATACCT ACAGCAAACA TGTCAAGTCC GAACCAAACC TGCACCCAGT ACTCATGTCG
GAGGCTCCGT GGAACACTCG GGCCAAGCGG GAGAAGCTGA CAGAGCTGAT GTTCGAGCAG
TACAACATTC CTGCCTTCTT CTTATGCAAG ACGGCCGTGC TCACAGCCTT TGCAAATGGA
CGCTCCACAG GCCTGGTGCT AGACAGCGGG GCCACCCACA CTACAGCCAT CCCAGTCCAT
GATGGCTATG TCCTACAGCA AGGCATCGTC AAGTCACCCC TGGCTGGCGA CTTCATATCC
ATGCAGTGCC GGGAGCTCTT CCAGGAAATG GCTATTGATA TCATCCCTCC TTACATGATT
GCTGCCAAGG AGCCTGTACG GGAGGGAGCC CCCCCAAACT GGAAGAAGAA GGAGAAGCTA
CCCCAAGTCT CCAAGTCCTG GCATAACTAC ATGTGTAACG AGGTGATCCA AGACTTCCAG
GCCTCTGTAC TGCAGGTGTC TGATTCCCCT TACGATGAAC AGGTAGCTGC ACAAATGCCC
ACAGTGCATT ATGAAATGCC CAATGGCTAC AACACAGACT ATGGTGCTGA GAGACTTCGC
ATCCCTGAGG GCCTGTTTGA TCCCTCTAAT GTCAAGGGTC TGTCTGGGAA CACCATGCTA
GGAGTGGGTC ACGTGGTCAC CACCAGCATC GGCATGTGTG ACATCGACAT TCGCCCGGGT
CTCTATGGCA GTGTCATTGT CACTGGCGGC AACACTCTGC TTCAGGGGTT CACAGACAGA
CTTAATCGGG AGCTTTCCCA GAAGACCCCA CCGAGCATGC GGCTCAAGCT TATCGCCAGC
AACAGCACCA TGGAACGCAA GTTCAGCCCC TGGATTGGGG GCTCCATCTT GGCCTCACTG
GGCACGTTCC AGCAGATGTG GATCTCCAAG CAGGAATATG AGGAGGGAGG GAAGCAGTGT
GTGGAGCGGA AGTGCCCCTG AThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa34747 Clone ID Related Accession (Same CDS sequence) XM_006249120.2 Accession Version XM_006249120.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1335bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product actin-like protein 6B isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006249120.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321ATGAGCGGGG GCGTCTACGG CGGAGATGAG GTGGGGGCGC TCGTCTTTGA CATTGGCTCC
TTCTCAGTCC GAGCTGGGTA CGCTGGGGAG GACTGCCCCA AGGTGAGCCT TCCAGTCCCC
TCCCCATATC CCAGGGGCTC GGACACCCTC TGCCAGGCTG ACTTCCCCAC CACTGTGGGG
CTGCTGGCCG CAGAAGAGGG GGGCGGGCTG GAGCTGGAGG GGGAGAAAGA GAAGAAAGGG
AAGATTTTCC ACATCGACAC CAATGCCCTG CACGTGCCTC GGGATGGAGC AGAGGTCATG
TCGCCCCTCA AGAACGGCAT GATTGAGGAC TGGGAGTGCT TCCGAGCCAT CCTGGATCAT
ACCTACAGCA AACATGTCAA GTCCGAACCA AACCTGCACC CAGTACTCAT GTCGGAGGCT
CCGTGGAACA CTCGGGCCAA GCGGGAGAAG CTGACAGAGC TGATGTTCGA GCAGTACAAC
ATTCCTGCCT TCTTCTTATG CAAGACGGCC GTGCTCACAG CCTTTGCAAA TGGACGCTCC
ACAGGCCTGG TGCTAGACAG CGGGGCCACC CACACTACAG CCATCCCAGT CCATGATGGC
TATGTCCTAC AGCAAGGCAT CGTCAAGTCA CCCCTGGCTG GCGACTTCAT ATCCATGCAG
TGCCGGGAGC TCTTCCAGGA AATGGCTATT GATATCATCC CTCCTTACAT GATTGCTGCC
AAGGAGCCTG TACGGGAGGG AGCCCCCCCA AACTGGAAGA AGAAGGAGAA GCTACCCCAA
GTCTCCAAGT CCTGGCATAA CTACATGTGT AACGAGGTGA TCCAAGACTT CCAGGCCTCT
GTACTGCAGG TGTCTGATTC CCCTTACGAT GAACAGGTAG CTGCACAAAT GCCCACAGTG
CATTATGAAA TGCCCAATGG CTACAACACA GACTATGGTG CTGAGAGACT TCGCATCCCT
GAGGGCCTGT TTGATCCCTC TAATGTCAAG GGTCTGTCTG GGAACACCAT GCTAGGAGTG
GGTCACGTGG TCACCACCAG CATCGGCATG TGTGACATCG ACATTCGCCC GGGTCTCTAT
GGCAGTGTCA TTGTCACTGG CGGCAACACT CTGCTTCAGG GGTTCACAGA CAGACTTAAT
CGGGAGCTTT CCCAGAAGAC CCCACCGAGC ATGCGGCTCA AGCTTATCGC CAGCAACAGC
ACCATGGAAC GCAAGTTCAG CCCCTGGATT GGGGGCTCCA TCTTGGCCTC ACTGGGCACG
TTCCAGCAGA TGTGGATCTC CAAGCAGGAA TATGAGGAGG GAGGGAAGCA GTGTGTGGAG
CGGAAGTGCC CCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006249182.1 CDS 108..1442 Translation
Target ORF information:
RefSeq Version XM_006249120.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus actin-like 6B (Actl6b), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006249120.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321ATGAGCGGGG GCGTCTACGG CGGAGATGAG GTGGGGGCGC TCGTCTTTGA CATTGGCTCC
TTCTCAGTCC GAGCTGGGTA CGCTGGGGAG GACTGCCCCA AGGTGAGCCT TCCAGTCCCC
TCCCCATATC CCAGGGGCTC GGACACCCTC TGCCAGGCTG ACTTCCCCAC CACTGTGGGG
CTGCTGGCCG CAGAAGAGGG GGGCGGGCTG GAGCTGGAGG GGGAGAAAGA GAAGAAAGGG
AAGATTTTCC ACATCGACAC CAATGCCCTG CACGTGCCTC GGGATGGAGC AGAGGTCATG
TCGCCCCTCA AGAACGGCAT GATTGAGGAC TGGGAGTGCT TCCGAGCCAT CCTGGATCAT
ACCTACAGCA AACATGTCAA GTCCGAACCA AACCTGCACC CAGTACTCAT GTCGGAGGCT
CCGTGGAACA CTCGGGCCAA GCGGGAGAAG CTGACAGAGC TGATGTTCGA GCAGTACAAC
ATTCCTGCCT TCTTCTTATG CAAGACGGCC GTGCTCACAG CCTTTGCAAA TGGACGCTCC
ACAGGCCTGG TGCTAGACAG CGGGGCCACC CACACTACAG CCATCCCAGT CCATGATGGC
TATGTCCTAC AGCAAGGCAT CGTCAAGTCA CCCCTGGCTG GCGACTTCAT ATCCATGCAG
TGCCGGGAGC TCTTCCAGGA AATGGCTATT GATATCATCC CTCCTTACAT GATTGCTGCC
AAGGAGCCTG TACGGGAGGG AGCCCCCCCA AACTGGAAGA AGAAGGAGAA GCTACCCCAA
GTCTCCAAGT CCTGGCATAA CTACATGTGT AACGAGGTGA TCCAAGACTT CCAGGCCTCT
GTACTGCAGG TGTCTGATTC CCCTTACGAT GAACAGGTAG CTGCACAAAT GCCCACAGTG
CATTATGAAA TGCCCAATGG CTACAACACA GACTATGGTG CTGAGAGACT TCGCATCCCT
GAGGGCCTGT TTGATCCCTC TAATGTCAAG GGTCTGTCTG GGAACACCAT GCTAGGAGTG
GGTCACGTGG TCACCACCAG CATCGGCATG TGTGACATCG ACATTCGCCC GGGTCTCTAT
GGCAGTGTCA TTGTCACTGG CGGCAACACT CTGCTTCAGG GGTTCACAGA CAGACTTAAT
CGGGAGCTTT CCCAGAAGAC CCCACCGAGC ATGCGGCTCA AGCTTATCGC CAGCAACAGC
ACCATGGAAC GCAAGTTCAG CCCCTGGATT GGGGGCTCCA TCTTGGCCTC ACTGGGCACG
TTCCAGCAGA TGTGGATCTC CAAGCAGGAA TATGAGGAGG GAGGGAAGCA GTGTGTGGAG
CGGAAGTGCC CCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.
American journal of human genetics104(5)815-834(2019 05)
Bell S,Rousseau J,Peng H,Aouabed Z,Priam P,Theroux JF,Jefri M,Tanti A,Wu H,Kolobova I,Silviera H,Manzano-Vargas K,Ehresmann S,Hamdan FF,Hettige N,Zhang X,Antonyan L,Nassif C,Ghaloul-Gonzalez L,Sebastian J,Vockley J,Begtrup AG,Wentzensen IM,Crunk A,Nicholls RD,Herman KC,Deignan JL,Al-Hertani W,Efthymiou S,Salpietro V,Miyake N,Makita Y,Matsumoto N,Østern R,Houge G,Hafström M,Fassi E,Houlden H,Klein Wassink-Ruiter JS,Nelson D,Goldstein A,Dabir T,van Gils J,Bourgeron T,Delorme R,Cooper GM,Martinez JE,Finnila CR,Carmant L,Lortie A,Oegema R,van Gassen K,Mehta SG,Huhle D,Abou Jamra R,Martin S,Brunner HG,Lindhout D,Au M,Graham JM Jr,Coubes C,Turecki G,Gravel S,Mechawar N,Rossignol E,Michaud JL,Lessard J,Ernst C,Campeau PM
miR-9*- and miR-124a-Mediated switching of chromatin remodelling complexes is altered in rat spina bifida aperta.
Neurochemical research38(8)1605-15(2013 Aug)
Wei X,Li H,Miao J,Liu B,Zhan Y,Wu D,Zhang Y,Wang L,Fan Y,Gu H,Wang W,Yuan Z
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(25)10348-61(2013 Jun)
Staahl BT,Tang J,Wu W,Sun A,Gitler AD,Yoo AS,Crabtree GR
The spectrum of SWI/SNF mutations, ubiquitous in human cancers.
PloS one8(1)e55119(2013)
Shain AH,Pollack JR
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.
Cell research21(3)396-420(2011 Mar)
Hargreaves DC,Crabtree GR
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