Gpr15 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gpr15
Entrez Gene ID	288181
Full Name	G protein-coupled receptor 15
General protein information	Preferred Names G protein-coupled receptor 15 Names G-protein coupled receptor 15
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105890.1	NP_001099360.1	G-protein coupled receptor 15
XM_017597937.1	XP_017453426.1	G-protein coupled receptor 15 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	GPR15	NP_005281.1
Pan troglodytes (chimpanzee)	GPR15	NP_001009030.1
Rattus norvegicus (Norway rat)	Gpr15	NP_001099360.1
Macaca mulatta (Rhesus monkey)	GPR15	NP_001036112.1
Bos taurus (cattle)	GPR15	XP_005201274.1
Gallus gallus (chicken)	GPR15	XP_004938269.1
Mus musculus (house mouse)	Gpr15	NP_001156427.1
Canis lupus familiaris (dog)	GPR15	XP_005639430.1

Gene Ontology
Bibliography

Related articles in PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Suply T, Hannedouche S, Carte N, Li J, Grosshans B, Schaefer M, Raad L, Beck V, Vidal S, Hiou-Feige A, Beluch N, Barbieri S, Wirsching J, Lageyre N, Hillger F, Debon C, Dawson J, Smith P, Lannoy V, Detheux M, Bitsch F, Falchetto R, Bouwmeester T, Porter J, Baumgarten B, Mansfield K, Carballido JM, Seuwen K, Bassilana F
Science signaling10(496)(2017 Sep)

Differential phosphorylation signals control endocytosis of GPR15.
Okamoto Y, Shikano S
Molecular biology of the cell28(17)2267-2281(2017 Aug)

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Ocón B, Pan J, Dinh TT, Chen W, Ballet R, Bscheider M, Habtezion A, Tu H, Zabel BA, Butcher EC
Frontiers in immunology81111(2017)

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
Kim SV, Xiang WV, Kwak C, Yang Y, Lin XW, Ota M, Sarpel U, Rifkin DB, Xu R, Littman DR
Science (New York, N.Y.)340(6139)1456-9(2013 Jun)

CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.
Blaak H, Boers PH, Gruters RA, Schuitemaker H, van der Ende ME, Osterhaus AD
Journal of virology79(3)1686-700(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gpr15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gpr15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41465	NM_001105890.1 Latest version!	Rattus norvegicus G protein-coupled receptor 15 (Gpr15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa41465	XM_017597937.1 Latest version!	Rattus norvegicus G protein-coupled receptor 15 (Gpr15), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gpr15 ( NM_001105890.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099360.1 Rattus norvegicus G protein-coupled receptor 15 (Gpr15), mRNA.

Price & Availability↑

CloneID	ORa41465
Clone ID Related Accession (Same CDS sequence)	NM_001105890.1 , XM_017597937.1
Accession Version	NM_001105890.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1517673600000
Organism	Rattus norvegicus(Norway rat)
Product	G-protein coupled receptor 15
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473967.1. On or before Oct 3, 2007 this sequence version replaced XM_221546.1, XM_001059659.1.

ATGGAACCAG CAACAACCCT GTTTTATCTG GATTACTATG ATGCTACGAG CCCGGATCCT 
CGTATCATGG AGACTCCCTC CCACACTTCC TACACATCTG TCTTCCTCCC TGTCTTTTAC 
ACAGCTGTGT TCCTGACTGG AGTGTTGGGG AATTTCATCC TCATGGTCAC TCTGCATTTC 
AAACACCGCA ACCGAAGATT GATCGATATC TTTATCATCA ACCTGGCTGC CTCGGACTTC 
ATTTTCCTTG TCACACTGCC ACTTTGGGTA GATAAGGAAG CCTCTCTGGG ACTGTGGAGG 
ACTGGCTCTC TCCTGTGCAA AGGCAGCTCC TATACGATCT CAGTGAACAT GCACTGTAAT 
GTCTTCTTGC TCACGTGTAT GAGCATGGAC CGCTACCTGG CCATCATGCG CCCAACCTTA 
GCCAGGAGAT TAAGAAGGAG AAGCTGTGCA TACGCGGTGT GTGCTGTCAT CTGGATCATC 
TCATGCCTCT TAGGATTACC CACTCTTCTG TCCAGAGGGC TCACTCACAT TGAAGGCAAG 
CCGTACTGTG CAGAGAAGAA ACCCACGTCA TTAAAACTGA TGTGGGGGCT GGTAGCCTTG 
ATTGCCACCT TTTTTGTCCC CCTCCTGAGC ATTGTGTCCA GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAATTGAG GAAGTCCATA 
AAGATCATCG TTATTGTGGT GGCGGCCTTC ACCATCTCCT GGGTGCCCTT TAACACTGTC 
AAGCTCCTAG CCATTGTTTC AGGATTGCAA CCTGAAAGCC AGTTTCCCTC CGAGTCTCTT 
CAGCAGGCCA TGAAGGTGAC TGGGTCCTTG GCATTTGCCA ACAGCTGCGT CAACCCTCTC 
CTTTACTATA TCTTTGACAG CTATATCCGC CGGGCCATTG TACGCAGTCT GTGCCCTTGT 
CTGAAGATCC ACAACATTGG GAGTAGCACT GAGACATTAG ACAGTCACCT CACCAAGGCT 
CTTGCCAACT TCATTCACTC AGAAGATTTT GTCAAGCGGA GGAAGAGGTC TGTGTCACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099360.1
CDS	1..1083
Translation	MEPATTLFYLDYYDATSPDPRIMETPSHTSYTSVFLPVFYTAVFLTGVLGNFILMVTLHFKHRNRRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLWRTGSLLCKGSSYTISVNMHCNVFLLTCMSMDRYLAIMRPTLARRLRRRSCAYAVCAVIWIISCLLGLPTLLSRGLTHIEGKPYCAEKKPTSLKLMWGLVALIATFFVPLLSIVSSYCCITRRLCAHYQQSGKHNKKLRKSIKIIVIVVAAFTISWVPFNTVKLLAIVSGLQPESQFPSESLQQAMKVTGSLAFANSCVNPLLYYIFDSYIRRAIVRSLCPCLKIHNIGSSTETLDSHLTKALANFIHSEDFVKRRKRSVSL

Target ORF information:

RefSeq Version	NM_001105890.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor 15 (Gpr15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105890.1

ORF Insert Sequence:

ATGGAACCAG CAACAACCCT GTTTTATCTG GATTACTATG ATGCTACGAG CCCGGATCCT 
CGTATCATGG AGACTCCCTC CCACACTTCC TACACATCTG TCTTCCTCCC TGTCTTTTAC 
ACAGCTGTGT TCCTGACTGG AGTGTTGGGG AATTTCATCC TCATGGTCAC TCTGCATTTC 
AAACACCGCA ACCGAAGATT GATCGATATC TTTATCATCA ACCTGGCTGC CTCGGACTTC 
ATTTTCCTTG TCACACTGCC ACTTTGGGTA GATAAGGAAG CCTCTCTGGG ACTGTGGAGG 
ACTGGCTCTC TCCTGTGCAA AGGCAGCTCC TATACGATCT CAGTGAACAT GCACTGTAAT 
GTCTTCTTGC TCACGTGTAT GAGCATGGAC CGCTACCTGG CCATCATGCG CCCAACCTTA 
GCCAGGAGAT TAAGAAGGAG AAGCTGTGCA TACGCGGTGT GTGCTGTCAT CTGGATCATC 
TCATGCCTCT TAGGATTACC CACTCTTCTG TCCAGAGGGC TCACTCACAT TGAAGGCAAG 
CCGTACTGTG CAGAGAAGAA ACCCACGTCA TTAAAACTGA TGTGGGGGCT GGTAGCCTTG 
ATTGCCACCT TTTTTGTCCC CCTCCTGAGC ATTGTGTCCA GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAATTGAG GAAGTCCATA 
AAGATCATCG TTATTGTGGT GGCGGCCTTC ACCATCTCCT GGGTGCCCTT TAACACTGTC 
AAGCTCCTAG CCATTGTTTC AGGATTGCAA CCTGAAAGCC AGTTTCCCTC CGAGTCTCTT 
CAGCAGGCCA TGAAGGTGAC TGGGTCCTTG GCATTTGCCA ACAGCTGCGT CAACCCTCTC 
CTTTACTATA TCTTTGACAG CTATATCCGC CGGGCCATTG TACGCAGTCT GTGCCCTTGT 
CTGAAGATCC ACAACATTGG GAGTAGCACT GAGACATTAG ACAGTCACCT CACCAAGGCT 
CTTGCCAACT TCATTCACTC AGAAGATTTT GTCAAGCGGA GGAAGAGGTC TGTGTCACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gpr15 ( XM_017597937.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453426.1 Rattus norvegicus G protein-coupled receptor 15 (Gpr15), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa41465
Clone ID Related Accession (Same CDS sequence)	NM_001105890.1 , XM_017597937.1
Accession Version	XM_017597937.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	G-protein coupled receptor 15 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCAG CAACAACCCT GTTTTATCTG GATTACTATG ATGCTACGAG CCCGGATCCT 
CGTATCATGG AGACTCCCTC CCACACTTCC TACACATCTG TCTTCCTCCC TGTCTTTTAC 
ACAGCTGTGT TCCTGACTGG AGTGTTGGGG AATTTCATCC TCATGGTCAC TCTGCATTTC 
AAACACCGCA ACCGAAGATT GATCGATATC TTTATCATCA ACCTGGCTGC CTCGGACTTC 
ATTTTCCTTG TCACACTGCC ACTTTGGGTA GATAAGGAAG CCTCTCTGGG ACTGTGGAGG 
ACTGGCTCTC TCCTGTGCAA AGGCAGCTCC TATACGATCT CAGTGAACAT GCACTGTAAT 
GTCTTCTTGC TCACGTGTAT GAGCATGGAC CGCTACCTGG CCATCATGCG CCCAACCTTA 
GCCAGGAGAT TAAGAAGGAG AAGCTGTGCA TACGCGGTGT GTGCTGTCAT CTGGATCATC 
TCATGCCTCT TAGGATTACC CACTCTTCTG TCCAGAGGGC TCACTCACAT TGAAGGCAAG 
CCGTACTGTG CAGAGAAGAA ACCCACGTCA TTAAAACTGA TGTGGGGGCT GGTAGCCTTG 
ATTGCCACCT TTTTTGTCCC CCTCCTGAGC ATTGTGTCCA GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAATTGAG GAAGTCCATA 
AAGATCATCG TTATTGTGGT GGCGGCCTTC ACCATCTCCT GGGTGCCCTT TAACACTGTC 
AAGCTCCTAG CCATTGTTTC AGGATTGCAA CCTGAAAGCC AGTTTCCCTC CGAGTCTCTT 
CAGCAGGCCA TGAAGGTGAC TGGGTCCTTG GCATTTGCCA ACAGCTGCGT CAACCCTCTC 
CTTTACTATA TCTTTGACAG CTATATCCGC CGGGCCATTG TACGCAGTCT GTGCCCTTGT 
CTGAAGATCC ACAACATTGG GAGTAGCACT GAGACATTAG ACAGTCACCT CACCAAGGCT 
CTTGCCAACT TCATTCACTC AGAAGATTTT GTCAAGCGGA GGAAGAGGTC TGTGTCACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453426.1
CDS	1474..2556
Translation	MEPATTLFYLDYYDATSPDPRIMETPSHTSYTSVFLPVFYTAVFLTGVLGNFILMVTLHFKHRNRRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLWRTGSLLCKGSSYTISVNMHCNVFLLTCMSMDRYLAIMRPTLARRLRRRSCAYAVCAVIWIISCLLGLPTLLSRGLTHIEGKPYCAEKKPTSLKLMWGLVALIATFFVPLLSIVSSYCCITRRLCAHYQQSGKHNKKLRKSIKIIVIVVAAFTISWVPFNTVKLLAIVSGLQPESQFPSESLQQAMKVTGSLAFANSCVNPLLYYIFDSYIRRAIVRSLCPCLKIHNIGSSTETLDSHLTKALANFIHSEDFVKRRKRSVSL

Target ORF information:

RefSeq Version	XM_017597937.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor 15 (Gpr15), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597937.1

ORF Insert Sequence:

ATGGAACCAG CAACAACCCT GTTTTATCTG GATTACTATG ATGCTACGAG CCCGGATCCT 
CGTATCATGG AGACTCCCTC CCACACTTCC TACACATCTG TCTTCCTCCC TGTCTTTTAC 
ACAGCTGTGT TCCTGACTGG AGTGTTGGGG AATTTCATCC TCATGGTCAC TCTGCATTTC 
AAACACCGCA ACCGAAGATT GATCGATATC TTTATCATCA ACCTGGCTGC CTCGGACTTC 
ATTTTCCTTG TCACACTGCC ACTTTGGGTA GATAAGGAAG CCTCTCTGGG ACTGTGGAGG 
ACTGGCTCTC TCCTGTGCAA AGGCAGCTCC TATACGATCT CAGTGAACAT GCACTGTAAT 
GTCTTCTTGC TCACGTGTAT GAGCATGGAC CGCTACCTGG CCATCATGCG CCCAACCTTA 
GCCAGGAGAT TAAGAAGGAG AAGCTGTGCA TACGCGGTGT GTGCTGTCAT CTGGATCATC 
TCATGCCTCT TAGGATTACC CACTCTTCTG TCCAGAGGGC TCACTCACAT TGAAGGCAAG 
CCGTACTGTG CAGAGAAGAA ACCCACGTCA TTAAAACTGA TGTGGGGGCT GGTAGCCTTG 
ATTGCCACCT TTTTTGTCCC CCTCCTGAGC ATTGTGTCCA GCTACTGTTG CATCACAAGG 
AGGCTGTGTG CTCATTACCA GCAGTCGGGA AAGCATAACA AGAAATTGAG GAAGTCCATA 
AAGATCATCG TTATTGTGGT GGCGGCCTTC ACCATCTCCT GGGTGCCCTT TAACACTGTC 
AAGCTCCTAG CCATTGTTTC AGGATTGCAA CCTGAAAGCC AGTTTCCCTC CGAGTCTCTT 
CAGCAGGCCA TGAAGGTGAC TGGGTCCTTG GCATTTGCCA ACAGCTGCGT CAACCCTCTC 
CTTTACTATA TCTTTGACAG CTATATCCGC CGGGCCATTG TACGCAGTCT GTGCCCTTGT 
CTGAAGATCC ACAACATTGG GAGTAGCACT GAGACATTAG ACAGTCACCT CACCAAGGCT 
CTTGCCAACT TCATTCACTC AGAAGATTTT GTCAAGCGGA GGAAGAGGTC TGTGTCACTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.
Science signaling10(496)(2017 Sep)
Suply T,Hannedouche S,Carte N,Li J,Grosshans B,Schaefer M,Raad L,Beck V,Vidal S,Hiou-Feige A,Beluch N,Barbieri S,Wirsching J,Lageyre N,Hillger F,Debon C,Dawson J,Smith P,Lannoy V,Detheux M,Bitsch F,Falchetto R,Bouwmeester T,Porter J,Baumgarten B,Mansfield K,Carballido JM,Seuwen K,Bassilana F

Differential phosphorylation signals control endocytosis of GPR15.
Molecular biology of the cell28(17)2267-2281(2017 Aug)
Okamoto Y,Shikano S

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.
Frontiers in immunology81111(2017)
Ocón B,Pan J,Dinh TT,Chen W,Ballet R,Bscheider M,Habtezion A,Tu H,Zabel BA,Butcher EC

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
Science (New York, N.Y.)340(6139)1456-9(2013 Jun)
Kim SV,Xiang WV,Kwak C,Yang Y,Lin XW,Ota M,Sarpel U,Rifkin DB,Xu R,Littman DR

CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.
Journal of virology79(3)1686-700(2005 Feb)
Blaak H,Boers PH,Gruters RA,Schuitemaker H,van der Ende ME,Osterhaus AD

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Gpr15 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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