| Gene Symbol | Yars2 |
| Entrez Gene ID | 287924 |
| Full Name | tyrosyl-tRNA synthetase 2 |
| Synonyms | CGI-04,RGD1311696 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Yars2 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Yars2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Yars2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa12982 Clone ID Related Accession (Same CDS sequence) NM_001009627.1 Accession Version NM_001009627.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1416bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550246400000 Organism Rattus norvegicus(Norway rat) Product tyrosine--tRNA ligase, mitochondrial Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC088224.1. On Jan 13, 2005 this sequence version replaced XM_213561.2. ##Evidence-Data-START## Transcript exon combination :: BC088224.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381ATGGCGGCGC CCATGCTGAG ACACCTGTGC CGCGTTCCGC AGTCAGGGGT CTGGACACGG
GGGCCGCGTG CGGTGCGCCC TGGCGCGCGG GGAATGTTGG TGGCACCAAG GGCCCGCGGC
CTGTTCAAGG AGTTCTTCCC CGAGAGCGGC ACGAAGACAG AGCTCCCCGA ACTCTTTGAC
CGCCGCAGGG CGGGTTCGCC CCAGACTGTG TACTGCGGTT TCGACCCCAC GGGCGATTCG
CTGCACGTGG GGCACCTGTT AACTTTATTG GGTCTGTTCC ACTTCCAGCG AGCCGGCCAC
AACGTGATCG CGCTCGTGGG AGGCTCCACG GCTCTCCTGG GAGACCCCAG CGGCCGGACC
AAGGAGCGCG AGGCGCTGAG CGCTGAGTGC GTGCGGGCCA ACGCGCGCGC CCTGCAGCGA
GGGCTGGAGA CCTTGGCGGC CAACCACGCG CGCCTCTTCG CGGACGGGCG GCCCTGGGGC
ACTTTCACGG TGCTCGACAA TGCAGCCTGG TTCCAGAAGC AGCACCTAAT GGATTTTCTG
GCCACGGTGG GCGGCCACTT CCGCATGGGC ACTCTGCTTA GCCGGCTGAG CGTGCAGTCC
CGTCTCAAGA GCCCAGAGGG CATGAGCTTG GCTGAGTTCT TTTACCAGGT GCTCCAGGCC
TATGACTTCT ACTACCTTTT CCGGCACTAT GGATGCCGGG TCCAGCTGGG CGGATCAGAT
CAGTTGGGCA ACATCATGTC TGGCTACGAG TTTATCCACA AGTTGACTGG AGAAGATGTG
TTTGGAATCA CTGTACCTCT AATTACAAGT ACAACTGGAG CGAAGCTGGG AAAGTCTGCT
GGCAACGCGG TTTGGCTAAA CAGAGAGAAA ACATCTCCGT TTGAACTTTA CCAGTTCTTT
ATCAGACAGC AAGATGATTC TGTAGAAAGG TACCTGAAGC TTTTCACTTT CCTTCCCCTC
CCAGAGATTG ATCATATTAT GCAGCTACAT GTCAAAGAAC CAGAAAAGCG AATTGCTCAG
AAACGACTTG CTGCAGAAGT AACAAAGCTT GTTCATGGAC AAGAAGGTCT GGACTCTGCG
AAAAGGTGTA CACAAGCCCT TTACCATAGC AGCATAGAGG CACTGGAGGT CATGTCTGAC
CAAGAGTTAA AGGAATTGTT TAAAGAAGCT TCATTTTCTG AATTAGTTCT TGACCCTGGA
ACGAGTGTCA TAGACACATG CCGTAAAGCA AATGCCATTC CTGATGGTCC CCGAGGGTAT
CGGATGATCA CAGAAGGTGG AGTCAGTATA AATCACAGAC AGGTAACAAA TCCTGAAAGT
GTTTTAGTAA TTGGACAACA TATTCTCAAG AATGGACTTT CCTTACTTAA AATAGGAAAA
AGGAATTTCT ACATTATAAA ATGGCTTCAG TTGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001009627.1 CDS 7..1422 Translation 
Target ORF information:
RefSeq Version NM_001009627.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus tyrosyl-tRNA synthetase 2 (Yars2), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001009627.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381ATGGCGGCGC CCATGCTGAG ACACCTGTGC CGCGTTCCGC AGTCAGGGGT CTGGACACGG
GGGCCGCGTG CGGTGCGCCC TGGCGCGCGG GGAATGTTGG TGGCACCAAG GGCCCGCGGC
CTGTTCAAGG AGTTCTTCCC CGAGAGCGGC ACGAAGACAG AGCTCCCCGA ACTCTTTGAC
CGCCGCAGGG CGGGTTCGCC CCAGACTGTG TACTGCGGTT TCGACCCCAC GGGCGATTCG
CTGCACGTGG GGCACCTGTT AACTTTATTG GGTCTGTTCC ACTTCCAGCG AGCCGGCCAC
AACGTGATCG CGCTCGTGGG AGGCTCCACG GCTCTCCTGG GAGACCCCAG CGGCCGGACC
AAGGAGCGCG AGGCGCTGAG CGCTGAGTGC GTGCGGGCCA ACGCGCGCGC CCTGCAGCGA
GGGCTGGAGA CCTTGGCGGC CAACCACGCG CGCCTCTTCG CGGACGGGCG GCCCTGGGGC
ACTTTCACGG TGCTCGACAA TGCAGCCTGG TTCCAGAAGC AGCACCTAAT GGATTTTCTG
GCCACGGTGG GCGGCCACTT CCGCATGGGC ACTCTGCTTA GCCGGCTGAG CGTGCAGTCC
CGTCTCAAGA GCCCAGAGGG CATGAGCTTG GCTGAGTTCT TTTACCAGGT GCTCCAGGCC
TATGACTTCT ACTACCTTTT CCGGCACTAT GGATGCCGGG TCCAGCTGGG CGGATCAGAT
CAGTTGGGCA ACATCATGTC TGGCTACGAG TTTATCCACA AGTTGACTGG AGAAGATGTG
TTTGGAATCA CTGTACCTCT AATTACAAGT ACAACTGGAG CGAAGCTGGG AAAGTCTGCT
GGCAACGCGG TTTGGCTAAA CAGAGAGAAA ACATCTCCGT TTGAACTTTA CCAGTTCTTT
ATCAGACAGC AAGATGATTC TGTAGAAAGG TACCTGAAGC TTTTCACTTT CCTTCCCCTC
CCAGAGATTG ATCATATTAT GCAGCTACAT GTCAAAGAAC CAGAAAAGCG AATTGCTCAG
AAACGACTTG CTGCAGAAGT AACAAAGCTT GTTCATGGAC AAGAAGGTCT GGACTCTGCG
AAAAGGTGTA CACAAGCCCT TTACCATAGC AGCATAGAGG CACTGGAGGT CATGTCTGAC
CAAGAGTTAA AGGAATTGTT TAAAGAAGCT TCATTTTCTG AATTAGTTCT TGACCCTGGA
ACGAGTGTCA TAGACACATG CCGTAAAGCA AATGCCATTC CTGATGGTCC CCGAGGGTAT
CGGATGATCA CAGAAGGTGG AGTCAGTATA AATCACAGAC AGGTAACAAA TCCTGAAAGT
GTTTTAGTAA TTGGACAACA TATTCTCAAG AATGGACTTT CCTTACTTAA AATAGGAAAA
AGGAATTTCT ACATTATAAA ATGGCTTCAG TTGTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M
Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome.
American journal of human genetics87(1)52-9(2010 Jul)
Riley LG,Cooper S,Hickey P,Rudinger-Thirion J,McKenzie M,Compton A,Lim SC,Thorburn D,Ryan MT,Giegé R,Bahlo M,Christodoulou J
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features.
Structure (London, England : 1993)15(11)1505-16(2007 Nov)
Bonnefond L,Frugier M,Touzé E,Lorber B,Florentz C,Giegé R,Sauter C,Rudinger-Thirion J
Human mitochondrial TyrRS disobeys the tyrosine identity rules.
RNA (New York, N.Y.)11(5)558-62(2005 May)
Bonnefond L,Frugier M,Giegé R,Rudinger-Thirion J
Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS.
Biochemistry44(12)4805-16(2005 Mar)
Bonnefond L,Fender A,Rudinger-Thirion J,Giegé R,Florentz C,Sissler M
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