Gas2l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gas2l2
Entrez Gene ID	287570
Full Name	growth arrest-specific 2 like 2
Synonyms	Gas2
General protein information	Preferred Names growth arrest-specific 2 like 2 Names GAS2-like protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q26

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105823.2	NP_001099293.2	GAS2-like protein 2

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	GAS2L2	XP_001114413.1
Rattus norvegicus (Norway rat)	Gas2l2	NP_001099293.2
Homo sapiens (human)	GAS2L2	NP_644814.1
Pan troglodytes (chimpanzee)	GAS2L2	XP_001174066.1
Bos taurus (cattle)	GAS2L2	NP_001192571.1
Mus musculus (house mouse)	Gas2l2	NP_001013781.1
Rattus norvegicus (Norway rat)	LOC100912215	XP_003750924.1
Canis lupus familiaris (dog)	GAS2L2	XP_005625054.1

Gene Ontology
Bibliography

Related articles in PubMed

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance.
Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refabért L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE
American journal of human genetics104(2)229-245(2019 02)

GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.
Stroud MJ, Nazgiewicz A, McKenzie EA, Wang Y, Kammerer RA, Ballestrem C
Journal of cell science127(Pt 12)2672-82(2014 Jun)

A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.
Wu YC, Lai HL, Chang WC, Lin JT, Liu YJ, Chern Y
Biochimica et biophysica acta1833(12)3145-3154(2013 Dec)

Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.
Goriounov D, Leung CL, Liem RK
Journal of cell science116(Pt 6)1045-58(2003 Mar)

Growth arrest-specific 2 gene expression during patellar tendon healing.
Lee KK, Cai DQ, Tang MK, Tsang KF, Kwong WH, Chow PH
Cells, tissues, organs173(3)138-46(2003)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gas2l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gas2l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12182	NM_001105823.2 Latest version!	Rattus norvegicus growth arrest-specific 2 like 2 (Gas2l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gas2l2 ( NM_001105823.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099293.2 Rattus norvegicus growth arrest-specific 2 like 2 (Gas2l2), mRNA.

Price & Availability↑

CloneID	ORa12182
Clone ID Related Accession (Same CDS sequence)	NM_001105823.2
Accession Version	NM_001105823.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2574bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Rattus norvegicus(Norway rat)
Product	GAS2-like protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC119615.7. On or before Sep 2, 2010 this sequence version replaced XM_220783.4, XM_001081061.2, NM_001105823.1. This RefSeq record was created from genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689599, SAMEA2689601 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGTCTCAGC ATGTGGGACA CGGGAGGAAA CCCAGGACCC CAGGACCTCC TGTGCGCAGC 
ATCCGACCCT TCAAGTCCAG CGAGCAGTAC CTGGAGGTCA TGAAGGAAGA CCTGGCTGAG 
TGGCTTCGGG ATCTGTACGG GCTGGACATT GACGCAGCCA ACTTCCTGCG GGTGCTGGAG 
ACTGGCCTGG TGTTGTGCCG GCATGCCAAC ACCGTCACGG AGGCTGCTCT GGCTTTCCTG 
GCTGAGGCAC CTGAGAGAGT TCAAAAGATT CCCATGCCCC AGGTTGGCGT TTTCTGCAAT 
GGGGCTGCTC AGCCGGGTAC GTTCCAGGCC AGGGACAACA TCTCCAACTT TATCCAGTGG 
TGTCGCAAGG AGATGGGGAT CCAAGAGGTG CTGATGTTCG AGACAGAGGA CCTGGTACTA 
CGCAAGAACG TCAAGAGCGT GGTATTATGT CTACTGGAGC TGGGTCGCCG CGCTTGGCGC 
TTTGGGGTGG CAGCGCCCTC CCTGGTGTAT CTGGAAGAGG AAATTGAGGA GGAGCTGCGG 
CGCGACCTGG ACCTGCCCTC CCCGGACCCG CCACCACCCG TACCCCCTGC CCGCAGGCCT 
TGCCACTTCC ACAACCTGGA CCAGATGGTG CAGAGCCTTG TGAGCCACTG CACATGCCCA 
GTGCAATTCT CCATGGTCAA GATATCTGAT GGCAAGTACA GAGTGGGGGA CTCCAACACT 
CTCATCTTCA TCCGGATCCT CCGGAGCCAC GTGATGGTAC GTGTTGGGGG TGGCTGGGAC 
ACGCTGGGTC ATTATCTGGA TAAACATGAC CCCTGCCGGT GCACATCCCT CTCCCACAAA 
CCAGGCAGCT TCCTGAAGCC TCCAGGACCA CCGGTGCAGC ATGAAGTGAA GGTACAGGAT 
GGGCCTTCAC AGCCCCAGCC TCTGATGACC ATCAGCCGCT CACAGAGCCC ACTGCCTCCA 
GTGGACTGGA AGACATACAC CTCTTCCAGC CGAAAACTGA GGCCTCCCAC TCCCTCTTCT 
TCTGGACCCC GTAGTGAATT CCCAGCGAGG GCCAGAACCC CTAGAGAGAT GGCTCCATTC 
CTGAGGTCCC AAGAAAAACC AACTCTGTCT CAGAGGATGT CATCACCTGG TCCCCAACTA 
TCATCTCCTT GTAGGGGACC AGACCTACAG AGTACCCTAT CAGAAAGGAG AGTAAATAGA 
AGCCCAGGTG AACTGCCCAG AGGAAGGACA CCCACGTCTT GGGTTCCCAA GGAAGCAGAC 
AGTCAAGGAG CACACACCAA GGCTCCCATA CCCCAGAGGC TCCAAATCCC TGAGACCACC 
AGTAAAAAGA CACCAGCAAG AGGACCATCT CCCCCACCTC GTTCCTCCAG CCTAGCCAGT 
CCTCACACTA TCTGGCTCCC CGACCAGGGA GCCTCCCCAG AGATTAGTGA ACCCATGTCT 
GCTCAATCTT CATCCCCTGG CAAAGGGCTC ACCAAGATCC CTATTCGGCT GTCCCCTGCC 
CGACCCCCAA CTCCAGGAAG AGGCTCTTTG GGTACTGAAG GTGGAGGCTC CATGCAGAGA 
GGTTCCCTCT CATCGAGGGC CCTTGCAGGG AATCTGGATA GATCTACACA TGGGCATCAT 
TCTGTGGACG TAAGCAAGGA CCACCAGAAA GTCATACAGA TTTCTTCAGG GACTGAAGAT 
CCCAGGAGCT TGGGTACACA GGAACGGAAA GAGAGATACA CCTCTCTGCC CCTGGGCAGG 
ACCAGAGAGC CAGCCCTCTA TGATAACCTT AAAGAGGAGC TTGTGGCCAA CATGAAACTG 
CTGGAGGTGG GGGCTGCCTG CACTCAGGGT ACAAGGTCTC AAGCCATCCC TCGAAGTGGG 
GTCTATGTCC CCAGCCTGGG TGGGATGTGG CCTGAGCCTA GGGGTCCTTA TGATAAAGTC 
ATCCAGGAAC TGGTTCAGGG TCCTCCACGC CTCCTAAAAG TGGATCTGAA AGCCTGGAAG 
GTAGGATCTG AATGCCTCCC TAGGCCAATT GTGAACCCAG GAAGCCCCAA AGAGGAGCAA 
GTTTCCAGAG AGAGGGGAAC AAGGAGAAAG GCACGCCCAA GTGCCCAGGG TACCACGGTG 
AAGACCACGT CACCTGCAAG AGGGCAGGAC TGCTCAACCT TGCCTGTATC TGCCAACCTG 
AAAGCTCCCA CACATTCATG TTCAGACCCC AGTTCTGATA AAGCCAAGGT ATGTCTGGGC 
AAGGGCAAAA GAACTCTCCG GAAACCCCAG AAGGTCCCAT CCATTTACAA GCTGAAGCTG 
AGACCCCGAA TCCGGCCCCG TAGAGACCAC AGGCCCGAAA AGAGACCTTC CAGGATTCCC 
AAGCCACTGG TTTACCCCTT CCTTGGTCCA GCCAGGACAG CTCCTGGAAG CAGGCTCTTA 
AAAGCTACAT TAGGTGGCAC AGGAGGGGAT GTGAATGGAG TAGGTAAAAA GGAGGAAGAG 
AAAAAGAAAG AAACCAGCAT CTCATTGGAG AGCAGCATCC AGCCTTCAGA GAGCCGGGAG 
CCTATGCAGC TTGATGGAAC CCCACTTCCA CCGGAGGAGG AATCTTGGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099293.2
CDS	1..2574
Translation	MSQHVGHGRKPRTPGPPVRSIRPFKSSEQYLEVMKEDLAEWLRDLYGLDIDAANFLRVLETGLVLCRHANTVTEAALAFLAEAPERVQKIPMPQVGVFCNGAAQPGTFQARDNISNFIQWCRKEMGIQEVLMFETEDLVLRKNVKSVVLCLLELGRRAWRFGVAAPSLVYLEEEIEEELRRDLDLPSPDPPPPVPPARRPCHFHNLDQMVQSLVSHCTCPVQFSMVKISDGKYRVGDSNTLIFIRILRSHVMVRVGGGWDTLGHYLDKHDPCRCTSLSHKPGSFLKPPGPPVQHEVKVQDGPSQPQPLMTISRSQSPLPPVDWKTYTSSSRKLRPPTPSSSGPRSEFPARARTPREMAPFLRSQEKPTLSQRMSSPGPQLSSPCRGPDLQSTLSERRVNRSPGELPRGRTPTSWVPKEADSQGAHTKAPIPQRLQIPETTSKKTPARGPSPPPRSSSLASPHTIWLPDQGASPEISEPMSAQSSSPGKGLTKIPIRLSPARPPTPGRGSLGTEGGGSMQRGSLSSRALAGNLDRSTHGHHSVDVSKDHQKVIQISSGTEDPRSLGTQERKERYTSLPLGRTREPALYDNLKEELVANMKLLEVGAACTQGTRSQAIPRSGVYVPSLGGMWPEPRGPYDKVIQELVQGPPRLLKVDLKAWKVGSECLPRPIVNPGSPKEEQVSRERGTRRKARPSAQGTTVKTTSPARGQDCSTLPVSANLKAPTHSCSDPSSDKAKVCLGKGKRTLRKPQKVPSIYKLKLRPRIRPRRDHRPEKRPSRIPKPLVYPFLGPARTAPGSRLLKATLGGTGGDVNGVGKKEEEKKKETSISLESSIQPSESREPMQLDGTPLPPEEESWV

Target ORF information:

RefSeq Version	NM_001105823.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus growth arrest-specific 2 like 2 (Gas2l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105823.2

ORF Insert Sequence:

ATGTCTCAGC ATGTGGGACA CGGGAGGAAA CCCAGGACCC CAGGACCTCC TGTGCGCAGC 
ATCCGACCCT TCAAGTCCAG CGAGCAGTAC CTGGAGGTCA TGAAGGAAGA CCTGGCTGAG 
TGGCTTCGGG ATCTGTACGG GCTGGACATT GACGCAGCCA ACTTCCTGCG GGTGCTGGAG 
ACTGGCCTGG TGTTGTGCCG GCATGCCAAC ACCGTCACGG AGGCTGCTCT GGCTTTCCTG 
GCTGAGGCAC CTGAGAGAGT TCAAAAGATT CCCATGCCCC AGGTTGGCGT TTTCTGCAAT 
GGGGCTGCTC AGCCGGGTAC GTTCCAGGCC AGGGACAACA TCTCCAACTT TATCCAGTGG 
TGTCGCAAGG AGATGGGGAT CCAAGAGGTG CTGATGTTCG AGACAGAGGA CCTGGTACTA 
CGCAAGAACG TCAAGAGCGT GGTATTATGT CTACTGGAGC TGGGTCGCCG CGCTTGGCGC 
TTTGGGGTGG CAGCGCCCTC CCTGGTGTAT CTGGAAGAGG AAATTGAGGA GGAGCTGCGG 
CGCGACCTGG ACCTGCCCTC CCCGGACCCG CCACCACCCG TACCCCCTGC CCGCAGGCCT 
TGCCACTTCC ACAACCTGGA CCAGATGGTG CAGAGCCTTG TGAGCCACTG CACATGCCCA 
GTGCAATTCT CCATGGTCAA GATATCTGAT GGCAAGTACA GAGTGGGGGA CTCCAACACT 
CTCATCTTCA TCCGGATCCT CCGGAGCCAC GTGATGGTAC GTGTTGGGGG TGGCTGGGAC 
ACGCTGGGTC ATTATCTGGA TAAACATGAC CCCTGCCGGT GCACATCCCT CTCCCACAAA 
CCAGGCAGCT TCCTGAAGCC TCCAGGACCA CCGGTGCAGC ATGAAGTGAA GGTACAGGAT 
GGGCCTTCAC AGCCCCAGCC TCTGATGACC ATCAGCCGCT CACAGAGCCC ACTGCCTCCA 
GTGGACTGGA AGACATACAC CTCTTCCAGC CGAAAACTGA GGCCTCCCAC TCCCTCTTCT 
TCTGGACCCC GTAGTGAATT CCCAGCGAGG GCCAGAACCC CTAGAGAGAT GGCTCCATTC 
CTGAGGTCCC AAGAAAAACC AACTCTGTCT CAGAGGATGT CATCACCTGG TCCCCAACTA 
TCATCTCCTT GTAGGGGACC AGACCTACAG AGTACCCTAT CAGAAAGGAG AGTAAATAGA 
AGCCCAGGTG AACTGCCCAG AGGAAGGACA CCCACGTCTT GGGTTCCCAA GGAAGCAGAC 
AGTCAAGGAG CACACACCAA GGCTCCCATA CCCCAGAGGC TCCAAATCCC TGAGACCACC 
AGTAAAAAGA CACCAGCAAG AGGACCATCT CCCCCACCTC GTTCCTCCAG CCTAGCCAGT 
CCTCACACTA TCTGGCTCCC CGACCAGGGA GCCTCCCCAG AGATTAGTGA ACCCATGTCT 
GCTCAATCTT CATCCCCTGG CAAAGGGCTC ACCAAGATCC CTATTCGGCT GTCCCCTGCC 
CGACCCCCAA CTCCAGGAAG AGGCTCTTTG GGTACTGAAG GTGGAGGCTC CATGCAGAGA 
GGTTCCCTCT CATCGAGGGC CCTTGCAGGG AATCTGGATA GATCTACACA TGGGCATCAT 
TCTGTGGACG TAAGCAAGGA CCACCAGAAA GTCATACAGA TTTCTTCAGG GACTGAAGAT 
CCCAGGAGCT TGGGTACACA GGAACGGAAA GAGAGATACA CCTCTCTGCC CCTGGGCAGG 
ACCAGAGAGC CAGCCCTCTA TGATAACCTT AAAGAGGAGC TTGTGGCCAA CATGAAACTG 
CTGGAGGTGG GGGCTGCCTG CACTCAGGGT ACAAGGTCTC AAGCCATCCC TCGAAGTGGG 
GTCTATGTCC CCAGCCTGGG TGGGATGTGG CCTGAGCCTA GGGGTCCTTA TGATAAAGTC 
ATCCAGGAAC TGGTTCAGGG TCCTCCACGC CTCCTAAAAG TGGATCTGAA AGCCTGGAAG 
GTAGGATCTG AATGCCTCCC TAGGCCAATT GTGAACCCAG GAAGCCCCAA AGAGGAGCAA 
GTTTCCAGAG AGAGGGGAAC AAGGAGAAAG GCACGCCCAA GTGCCCAGGG TACCACGGTG 
AAGACCACGT CACCTGCAAG AGGGCAGGAC TGCTCAACCT TGCCTGTATC TGCCAACCTG 
AAAGCTCCCA CACATTCATG TTCAGACCCC AGTTCTGATA AAGCCAAGGT ATGTCTGGGC 
AAGGGCAAAA GAACTCTCCG GAAACCCCAG AAGGTCCCAT CCATTTACAA GCTGAAGCTG 
AGACCCCGAA TCCGGCCCCG TAGAGACCAC AGGCCCGAAA AGAGACCTTC CAGGATTCCC 
AAGCCACTGG TTTACCCCTT CCTTGGTCCA GCCAGGACAG CTCCTGGAAG CAGGCTCTTA 
AAAGCTACAT TAGGTGGCAC AGGAGGGGAT GTGAATGGAG TAGGTAAAAA GGAGGAAGAG 
AAAAAGAAAG AAACCAGCAT CTCATTGGAG AGCAGCATCC AGCCTTCAGA GAGCCGGGAG 
CCTATGCAGC TTGATGGAAC CCCACTTCCA CCGGAGGAGG AATCTTGGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance.
American journal of human genetics104(2)229-245(2019 02)
Bustamante-Marin XM,Yin WN,Sears PR,Werner ME,Brotslaw EJ,Mitchell BJ,Jania CM,Zeman KL,Rogers TD,Herring LE,Refabért L,Thomas L,Amselem S,Escudier E,Legendre M,Grubb BR,Knowles MR,Zariwala MA,Ostrowski LE

GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins.
Journal of cell science127(Pt 12)2672-82(2014 Jun)
Stroud MJ,Nazgiewicz A,McKenzie EA,Wang Y,Kammerer RA,Ballestrem C

A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.
Biochimica et biophysica acta1833(12)3145-3154(2013 Dec)
Wu YC,Lai HL,Chang WC,Lin JT,Liu YJ,Chern Y

Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.
Journal of cell science116(Pt 6)1045-58(2003 Mar)
Goriounov D,Leung CL,Liem RK

Growth arrest-specific 2 gene expression during patellar tendon healing.
Cells, tissues, organs173(3)138-46(2003)
Lee KK,Cai DQ,Tang MK,Tsang KF,Kwong WH,Chow PH

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Gas2l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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