Camk4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Camk4
Entrez Gene ID	25050
Full Name	calcium/calmodulin-dependent protein kinase IV
Synonyms	Ccdpk,RATCCDPK
General protein information	Preferred Names calcium/calmodulin-dependent protein kinase IV Names calcium/calmodulin-dependent protein kinase type IV CAM kinase-GR Calmodulin-dependent protein kinase IV caMK IV calspermin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18p12
Summary	protein kinase that phosphorylates synapsin I; involved in neuronal calcium signaling; alternative transcript produces calspermin protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017600851.1	XP_017456340.1	calcium/calmodulin-dependent protein kinase type IV isoform X3
NM_012727.3	NP_036859.2	calcium/calmodulin-dependent protein kinase type IV
XM_017600850.1	XP_017456339.1	calcium/calmodulin-dependent protein kinase type IV isoform X1
XM_006254523.3	XP_006254585.1	calcium/calmodulin-dependent protein kinase type IV isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CAMK4	XP_517873.3
Xenopus tropicalis (tropical clawed frog)	camk4	XP_002943358.2
Rattus norvegicus (Norway rat)	Camk4	NP_036859.2
Gallus gallus (chicken)	CAMK4L	XP_424850.4
Danio rerio (zebrafish)	camk4	NP_001017607.1
Canis lupus familiaris (dog)	CAMK4	XP_005618268.1
Bos taurus (cattle)	CAMK4	XP_002691060.1
Macaca mulatta (Rhesus monkey)	CAMK4	XP_001101268.2
Gallus gallus (chicken)	CAMK4	NP_001029985.1
Homo sapiens (human)	CAMK4	NP_001735.1
Mus musculus (house mouse)	Camk4	NP_033923.2

Gene Ontology
Bibliography

Related articles in PubMed

All for One But Not One for All: Excitatory Synaptic Scaling and Intrinsic Excitability Are Coregulated by CaMKIV, Whereas Inhibitory Synaptic Scaling Is Under Independent Control.
Joseph A, Turrigiano GG
The Journal of neuroscience : the official journal of the Society for Neuroscience37(28)6778-6785(2017 07)

Inhibition of CaMKIV relieves streptozotocin-induced diabetic neuropathic pain through regulation of HMGB1.
Zhao X, Shen L, Xu L, Wang Z, Ma C, Huang Y
BMC anesthesiology16(1)27(2016 05)

Late maternal hypothyroidism alters the expression of Camk4 in neocortical subplate neurons: a comparison with Nurr1 labeling.
Navarro D, Alvarado M, Morte B, Berbel D, Sesma J, Pacheco P, Morreale de Escobar G, Bernal J, Berbel P
Cerebral cortex (New York, N.Y. : 1991)24(10)2694-706(2014 Oct)

IB4-binding sensory neurons in the adult rat express a novel 3' UTR-extended isoform of CaMK4 that is associated with its localization to axons.
Harrison BJ, Flight RM, Gomes C, Venkat G, Ellis SR, Sankar U, Twiss JL, Rouchka EC, Petruska JC
The Journal of comparative neurology522(2)308-36(2014 Feb)

Calcium/calmodulin-dependent protein kinase IV mediates distinct features of basal and activity-dependent dendrite complexity.
Nagendran T, Hardy LR
Neuroscience199548-62(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Camk4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Camk4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa00763	NM_012727.3 Latest version!	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa00763	XM_017600851.1 Latest version!	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa38261	XM_006254523.3 Latest version!	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa59211	XM_017600850.1 Latest version!	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Camk4 ( NM_012727.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036859.2 Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), mRNA.

Price & Availability↑

CloneID	ORa00763
Clone ID Related Accession (Same CDS sequence)	XM_017600851.1 , NM_012727.3
Accession Version	NM_012727.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568995200000
Organism	Rattus norvegicus(Norway rat)
Product	calcium/calmodulin-dependent protein kinase type IV
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC128706.1. On Jun 10, 2007 this sequence version replaced NM_012727.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC128706.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689604 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCAAAG TCACGGTGCC CTCCTGTCCC TCCTCGCCCT GCTCCTCGGT CACCTCCAGT 
ACTGAGAACC TCGTCCCGGA TTACTGGATC GACGGCTCTA AACGGGATCC TCTGAGCGAT 
TTCTTCGAGG TGGAGTCAGA GCTGGGACGG GGTGCTACAT CCATTGTGTA CAGATGCAAA 
CAGAAGGGGA CCCAGAAGCC CTATGCTCTC AAAGTGTTAA AGAAAACAGT GGACAAGAAG 
ATCGTGAGAA CTGAAATAGG AGTTCTCCTG AGACTCTCAC ACCCGAACAT CATAAAACTC 
AAGGAAATAT TTGAAACCCC CACAGAAATC AGCCTGGTTC TTGAGCTAGT CACAGGAGGA 
GAACTGTTTG ACAGGATTGT GGAGAAAGGC TATTACAGTG AACGCGACGC GGCCGATGCT 
GTGAAGCAGA TCCTGGAGGC AGTTGCTTAC CTGCACGAAA ATGGAATCGT CCATCGCGAC 
CTCAAACCAG AGAATCTTCT TTATGCAACG CCAGCCCCTG ATGCACCACT CAAAATTGCT 
GATTTTGGAC TTTCTAAAAT CGTGGAACAT CAAGTGCTCA TGAAGACGGT GTGTGGAACC 
CCGGGGTACT GTGCACCTGA GATTCTCCGA GGCTGTGCCT ATGGCCCCGA GGTGGACATG 
TGGTCTGTAG GAATAATTAC CTACATCCTA CTTTGTGGAT TTGAACCATT CTATGATGAG 
AGAGGTGATC AGTTCATGTT CAGGAGAATT CTGAATTGTG AATATTACTT TATCTCCCCC 
TGGTGGGATG AAGTTTCTTT AAATGCCAAG GACTTGGTCA AGAAACTCAT TGTTTTGGAC 
CCTAAGAAGC GGCTGACTAC ATTCCAAGCC CTCCAACACC CGTGGGTCAC AGGAAAAGCA 
GCCAACTTTG TCCACATGGA TACCGCTCAG AAAAAGCTTC AAGAATTCAA TGCTAGGCGC 
AAGCTTAAGG CGGCAGTGAA GGCTGTGGTG GCCTCTTCTC GGCTGGGAAG TGCCAGCAGC 
AGTCACACCA ACATCCAAGA AAGCAACAAA GCCAGCTCGG AGGCACAGCC CGCCCAAGAC 
GGCAAGGACA AGACAGATCC TCTGGAAAAC AAAATGCAAG CGGGGGACCA CGAGGCAGCC 
AAGGCTGCAG CCGATGAGAC GATGAAGCTA CAGTCCGAGG AGGTGGAGGA AGAGGAAGGT 
GTAAAAGAAG AGGAGGAAGA GGAAGAAGAG GAAGAGGAGA CCTCCAGGAT GGTACCTCAG 
GAGCCAGAGG ACAGGCTGGA GACAGATGAC CAGGAAATGA AGAGAAATTC AGAGGAGACG 
TTGAAGAGTG TGGAGGAAGA AATGGACCCG AAAGCTGAGG AGGAAGCCGC TGCCGTGGGA 
CTTGGGGTCC CTCCACAGCA GGATGCTATT CTGCCAGAGT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036859.2
CDS	229..1653
Translation	MLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY

Target ORF information:

RefSeq Version	NM_012727.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012727.3

ORF Insert Sequence:

ATGCTCAAAG TCACGGTGCC CTCCTGTCCC TCCTCGCCCT GCTCCTCGGT CACCTCCAGT 
ACTGAGAACC TCGTCCCGGA TTACTGGATC GACGGCTCTA AACGGGATCC TCTGAGCGAT 
TTCTTCGAGG TGGAGTCAGA GCTGGGACGG GGTGCTACAT CCATTGTGTA CAGATGCAAA 
CAGAAGGGGA CCCAGAAGCC CTATGCTCTC AAAGTGTTAA AGAAAACAGT GGACAAGAAG 
ATCGTGAGAA CTGAAATAGG AGTTCTCCTG AGACTCTCAC ACCCGAACAT CATAAAACTC 
AAGGAAATAT TTGAAACCCC CACAGAAATC AGCCTGGTTC TTGAGCTAGT CACAGGAGGA 
GAACTGTTTG ACAGGATTGT GGAGAAAGGC TATTACAGTG AACGCGACGC GGCCGATGCT 
GTGAAGCAGA TCCTGGAGGC AGTTGCTTAC CTGCACGAAA ATGGAATCGT CCATCGCGAC 
CTCAAACCAG AGAATCTTCT TTATGCAACG CCAGCCCCTG ATGCACCACT CAAAATTGCT 
GATTTTGGAC TTTCTAAAAT CGTGGAACAT CAAGTGCTCA TGAAGACGGT GTGTGGAACC 
CCGGGGTACT GTGCACCTGA GATTCTCCGA GGCTGTGCCT ATGGCCCCGA GGTGGACATG 
TGGTCTGTAG GAATAATTAC CTACATCCTA CTTTGTGGAT TTGAACCATT CTATGATGAG 
AGAGGTGATC AGTTCATGTT CAGGAGAATT CTGAATTGTG AATATTACTT TATCTCCCCC 
TGGTGGGATG AAGTTTCTTT AAATGCCAAG GACTTGGTCA AGAAACTCAT TGTTTTGGAC 
CCTAAGAAGC GGCTGACTAC ATTCCAAGCC CTCCAACACC CGTGGGTCAC AGGAAAAGCA 
GCCAACTTTG TCCACATGGA TACCGCTCAG AAAAAGCTTC AAGAATTCAA TGCTAGGCGC 
AAGCTTAAGG CGGCAGTGAA GGCTGTGGTG GCCTCTTCTC GGCTGGGAAG TGCCAGCAGC 
AGTCACACCA ACATCCAAGA AAGCAACAAA GCCAGCTCGG AGGCACAGCC CGCCCAAGAC 
GGCAAGGACA AGACAGATCC TCTGGAAAAC AAAATGCAAG CGGGGGACCA CGAGGCAGCC 
AAGGCTGCAG CCGATGAGAC GATGAAGCTA CAGTCCGAGG AGGTGGAGGA AGAGGAAGGT 
GTAAAAGAAG AGGAGGAAGA GGAAGAAGAG GAAGAGGAGA CCTCCAGGAT GGTACCTCAG 
GAGCCAGAGG ACAGGCTGGA GACAGATGAC CAGGAAATGA AGAGAAATTC AGAGGAGACG 
TTGAAGAGTG TGGAGGAAGA AATGGACCCG AAAGCTGAGG AGGAAGCCGC TGCCGTGGGA 
CTTGGGGTCC CTCCACAGCA GGATGCTATT CTGCCAGAGT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Camk4 ( XM_017600851.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456340.1 Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa00763
Clone ID Related Accession (Same CDS sequence)	XM_017600851.1 , NM_012727.3
Accession Version	XM_017600851.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	calcium/calmodulin-dependent protein kinase type IV isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCAAAG TCACGGTGCC CTCCTGTCCC TCCTCGCCCT GCTCCTCGGT CACCTCCAGT 
ACTGAGAACC TCGTCCCGGA TTACTGGATC GACGGCTCTA AACGGGATCC TCTGAGCGAT 
TTCTTCGAGG TGGAGTCAGA GCTGGGACGG GGTGCTACAT CCATTGTGTA CAGATGCAAA 
CAGAAGGGGA CCCAGAAGCC CTATGCTCTC AAAGTGTTAA AGAAAACAGT GGACAAGAAG 
ATCGTGAGAA CTGAAATAGG AGTTCTCCTG AGACTCTCAC ACCCGAACAT CATAAAACTC 
AAGGAAATAT TTGAAACCCC CACAGAAATC AGCCTGGTTC TTGAGCTAGT CACAGGAGGA 
GAACTGTTTG ACAGGATTGT GGAGAAAGGC TATTACAGTG AACGCGACGC GGCCGATGCT 
GTGAAGCAGA TCCTGGAGGC AGTTGCTTAC CTGCACGAAA ATGGAATCGT CCATCGCGAC 
CTCAAACCAG AGAATCTTCT TTATGCAACG CCAGCCCCTG ATGCACCACT CAAAATTGCT 
GATTTTGGAC TTTCTAAAAT CGTGGAACAT CAAGTGCTCA TGAAGACGGT GTGTGGAACC 
CCGGGGTACT GTGCACCTGA GATTCTCCGA GGCTGTGCCT ATGGCCCCGA GGTGGACATG 
TGGTCTGTAG GAATAATTAC CTACATCCTA CTTTGTGGAT TTGAACCATT CTATGATGAG 
AGAGGTGATC AGTTCATGTT CAGGAGAATT CTGAATTGTG AATATTACTT TATCTCCCCC 
TGGTGGGATG AAGTTTCTTT AAATGCCAAG GACTTGGTCA AGAAACTCAT TGTTTTGGAC 
CCTAAGAAGC GGCTGACTAC ATTCCAAGCC CTCCAACACC CGTGGGTCAC AGGAAAAGCA 
GCCAACTTTG TCCACATGGA TACCGCTCAG AAAAAGCTTC AAGAATTCAA TGCTAGGCGC 
AAGCTTAAGG CGGCAGTGAA GGCTGTGGTG GCCTCTTCTC GGCTGGGAAG TGCCAGCAGC 
AGTCACACCA ACATCCAAGA AAGCAACAAA GCCAGCTCGG AGGCACAGCC CGCCCAAGAC 
GGCAAGGACA AGACAGATCC TCTGGAAAAC AAAATGCAAG CGGGGGACCA CGAGGCAGCC 
AAGGCTGCAG CCGATGAGAC GATGAAGCTA CAGTCCGAGG AGGTGGAGGA AGAGGAAGGT 
GTAAAAGAAG AGGAGGAAGA GGAAGAAGAG GAAGAGGAGA CCTCCAGGAT GGTACCTCAG 
GAGCCAGAGG ACAGGCTGGA GACAGATGAC CAGGAAATGA AGAGAAATTC AGAGGAGACG 
TTGAAGAGTG TGGAGGAAGA AATGGACCCG AAAGCTGAGG AGGAAGCCGC TGCCGTGGGA 
CTTGGGGTCC CTCCACAGCA GGATGCTATT CTGCCAGAGT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456340.1
CDS	235..1659
Translation	MLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY

Target ORF information:

RefSeq Version	XM_017600851.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600851.1

ORF Insert Sequence:

ATGCTCAAAG TCACGGTGCC CTCCTGTCCC TCCTCGCCCT GCTCCTCGGT CACCTCCAGT 
ACTGAGAACC TCGTCCCGGA TTACTGGATC GACGGCTCTA AACGGGATCC TCTGAGCGAT 
TTCTTCGAGG TGGAGTCAGA GCTGGGACGG GGTGCTACAT CCATTGTGTA CAGATGCAAA 
CAGAAGGGGA CCCAGAAGCC CTATGCTCTC AAAGTGTTAA AGAAAACAGT GGACAAGAAG 
ATCGTGAGAA CTGAAATAGG AGTTCTCCTG AGACTCTCAC ACCCGAACAT CATAAAACTC 
AAGGAAATAT TTGAAACCCC CACAGAAATC AGCCTGGTTC TTGAGCTAGT CACAGGAGGA 
GAACTGTTTG ACAGGATTGT GGAGAAAGGC TATTACAGTG AACGCGACGC GGCCGATGCT 
GTGAAGCAGA TCCTGGAGGC AGTTGCTTAC CTGCACGAAA ATGGAATCGT CCATCGCGAC 
CTCAAACCAG AGAATCTTCT TTATGCAACG CCAGCCCCTG ATGCACCACT CAAAATTGCT 
GATTTTGGAC TTTCTAAAAT CGTGGAACAT CAAGTGCTCA TGAAGACGGT GTGTGGAACC 
CCGGGGTACT GTGCACCTGA GATTCTCCGA GGCTGTGCCT ATGGCCCCGA GGTGGACATG 
TGGTCTGTAG GAATAATTAC CTACATCCTA CTTTGTGGAT TTGAACCATT CTATGATGAG 
AGAGGTGATC AGTTCATGTT CAGGAGAATT CTGAATTGTG AATATTACTT TATCTCCCCC 
TGGTGGGATG AAGTTTCTTT AAATGCCAAG GACTTGGTCA AGAAACTCAT TGTTTTGGAC 
CCTAAGAAGC GGCTGACTAC ATTCCAAGCC CTCCAACACC CGTGGGTCAC AGGAAAAGCA 
GCCAACTTTG TCCACATGGA TACCGCTCAG AAAAAGCTTC AAGAATTCAA TGCTAGGCGC 
AAGCTTAAGG CGGCAGTGAA GGCTGTGGTG GCCTCTTCTC GGCTGGGAAG TGCCAGCAGC 
AGTCACACCA ACATCCAAGA AAGCAACAAA GCCAGCTCGG AGGCACAGCC CGCCCAAGAC 
GGCAAGGACA AGACAGATCC TCTGGAAAAC AAAATGCAAG CGGGGGACCA CGAGGCAGCC 
AAGGCTGCAG CCGATGAGAC GATGAAGCTA CAGTCCGAGG AGGTGGAGGA AGAGGAAGGT 
GTAAAAGAAG AGGAGGAAGA GGAAGAAGAG GAAGAGGAGA CCTCCAGGAT GGTACCTCAG 
GAGCCAGAGG ACAGGCTGGA GACAGATGAC CAGGAAATGA AGAGAAATTC AGAGGAGACG 
TTGAAGAGTG TGGAGGAAGA AATGGACCCG AAAGCTGAGG AGGAAGCCGC TGCCGTGGGA 
CTTGGGGTCC CTCCACAGCA GGATGCTATT CTGCCAGAGT ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Camk4 ( XM_006254523.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254585.1 Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa38261
Clone ID Related Accession (Same CDS sequence)	XM_006254523.3
Accession Version	XM_006254523.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	calcium/calmodulin-dependent protein kinase type IV isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254523.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTGCG CCGGCAACGA TCAGGCGGCG GCCAGCGGTT CCAGCTCGGG CAGCGGCGGC 
ATCTTCCGGA GTCCCGCGGC GAAGATGCTC AAAGTCACGG TGCCCTCCTG TCCCTCCTCG 
CCCTGCTCCT CGGTCACCTC CAGTACTGAG AACCTCGTCC CGGATTACTG GATCGACGGC 
TCTAAACGGG ATCCTCTGAG CGATTTCTTC GAGGTGGAGT CAGAGCTGGG ACGGGGTGCT 
ACATCCATTG TGTACAGATG CAAACAGAAG GGGACCCAGA AGCCCTATGC TCTCAAAGTG 
TTAAAGAAAA CAGTGGACAA GAAGATCGTG AGAACTGAAA TAGGAGTTCT CCTGAGACTC 
TCACACCCGA ACATCATAAA ACTCAAGGAA ATATTTGAAA CCCCCACAGA AATCAGCCTG 
GTTCTTGAGC TAGTCACAGG AGGAGAACTG TTTGACAGGA TTGTGGAGAA AGGCTATTAC 
AGTGAACGCG ACGCGGCCGA TGCTGTGAAG CAGATCCTGG AGGCAGTTGC TTACCTGCAC 
GAAAATGGAA TCGTCCATCG CGACCTCAAA CCAGAGAATC TTCTTTATGC AACGCCAGCC 
CCTGATGCAC CACTCAAAAT TGCTGATTTT GGACTTTCTA AAATCGTGGA ACATCAAGTG 
CTCATGAAGA CGGTGTGTGG AACCCCGGGG TACTGTGCAC CTGAGATTCT CCGAGGCTGT 
GCCTATGGCC CCGAGGTGGA CATGTGGTCT GTAGGAATAA TTACCTACAT CCTACTTTGT 
GGATTTGAAC CATTCTATGA TGAGAGAGGT GATCAGTTCA TGTTCAGGAG AATTCTGAAT 
TGTGAATATT ACTTTATCTC CCCCTGGTGG GATGAAGTTT CTTTAAATGC CAAGGACTTG 
GTCAAGAAAC TCATTGTTTT GGACCCTAAG AAGCGGCTGA CTACATTCCA AGCCCTCCAA 
CACCCGTGGG TCACAGGAAA AGCAGCCAAC TTTGTCCACA TGGATACCGC TCAGAAAAAG 
CTTCAAGAAT TCAATGCTAG GCGCAAGCTT AAGGCGGCAG TGAAGGCTGT GGTGGCCTCT 
TCTCGGCTGG GAAGTGCCAG CAGCAGTCAC ACCAACATCC AAGAAAGCAA CAAAGCCAGC 
TCGGAGGCAC AGCCCGCCCA AGACGGCAAG GACAAGACAG ATCCTCTGGA AAACAAAATG 
CAAGCGGGGG ACCACGAGGC AGCCAAGGCT GCAGCCGATG AGACGATGAA GCTACAGTCC 
GAGGAGGTGG AGGAAGAGGA AGGTGTAAAA GAAGAGGAGG AAGAGGAAGA AGAGGAAGAG 
GAGACCTCCA GGATGGTACC TCAGGAGCCA GAGGACAGGC TGGAGACAGA TGACCAGGAA 
ATGAAGAGAA ATTCAGAGGA GACGTTGAAG AGTGTGGAGG AAGAAATGGA CCCGAAAGCT 
GAGGAGGAAG CCGCTGCCGT GGGACTTGGG GTCCCTCCAC AGCAGGATGC TATTCTGCCA 
GAGTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254585.1
CDS	84..1592
Translation	MSCAGNDQAAASGSSSGSGGIFRSPAAKMLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY

Target ORF information:

RefSeq Version	XM_006254523.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254523.3

ORF Insert Sequence:

ATGAGTTGCG CCGGCAACGA TCAGGCGGCG GCCAGCGGTT CCAGCTCGGG CAGCGGCGGC 
ATCTTCCGGA GTCCCGCGGC GAAGATGCTC AAAGTCACGG TGCCCTCCTG TCCCTCCTCG 
CCCTGCTCCT CGGTCACCTC CAGTACTGAG AACCTCGTCC CGGATTACTG GATCGACGGC 
TCTAAACGGG ATCCTCTGAG CGATTTCTTC GAGGTGGAGT CAGAGCTGGG ACGGGGTGCT 
ACATCCATTG TGTACAGATG CAAACAGAAG GGGACCCAGA AGCCCTATGC TCTCAAAGTG 
TTAAAGAAAA CAGTGGACAA GAAGATCGTG AGAACTGAAA TAGGAGTTCT CCTGAGACTC 
TCACACCCGA ACATCATAAA ACTCAAGGAA ATATTTGAAA CCCCCACAGA AATCAGCCTG 
GTTCTTGAGC TAGTCACAGG AGGAGAACTG TTTGACAGGA TTGTGGAGAA AGGCTATTAC 
AGTGAACGCG ACGCGGCCGA TGCTGTGAAG CAGATCCTGG AGGCAGTTGC TTACCTGCAC 
GAAAATGGAA TCGTCCATCG CGACCTCAAA CCAGAGAATC TTCTTTATGC AACGCCAGCC 
CCTGATGCAC CACTCAAAAT TGCTGATTTT GGACTTTCTA AAATCGTGGA ACATCAAGTG 
CTCATGAAGA CGGTGTGTGG AACCCCGGGG TACTGTGCAC CTGAGATTCT CCGAGGCTGT 
GCCTATGGCC CCGAGGTGGA CATGTGGTCT GTAGGAATAA TTACCTACAT CCTACTTTGT 
GGATTTGAAC CATTCTATGA TGAGAGAGGT GATCAGTTCA TGTTCAGGAG AATTCTGAAT 
TGTGAATATT ACTTTATCTC CCCCTGGTGG GATGAAGTTT CTTTAAATGC CAAGGACTTG 
GTCAAGAAAC TCATTGTTTT GGACCCTAAG AAGCGGCTGA CTACATTCCA AGCCCTCCAA 
CACCCGTGGG TCACAGGAAA AGCAGCCAAC TTTGTCCACA TGGATACCGC TCAGAAAAAG 
CTTCAAGAAT TCAATGCTAG GCGCAAGCTT AAGGCGGCAG TGAAGGCTGT GGTGGCCTCT 
TCTCGGCTGG GAAGTGCCAG CAGCAGTCAC ACCAACATCC AAGAAAGCAA CAAAGCCAGC 
TCGGAGGCAC AGCCCGCCCA AGACGGCAAG GACAAGACAG ATCCTCTGGA AAACAAAATG 
CAAGCGGGGG ACCACGAGGC AGCCAAGGCT GCAGCCGATG AGACGATGAA GCTACAGTCC 
GAGGAGGTGG AGGAAGAGGA AGGTGTAAAA GAAGAGGAGG AAGAGGAAGA AGAGGAAGAG 
GAGACCTCCA GGATGGTACC TCAGGAGCCA GAGGACAGGC TGGAGACAGA TGACCAGGAA 
ATGAAGAGAA ATTCAGAGGA GACGTTGAAG AGTGTGGAGG AAGAAATGGA CCCGAAAGCT 
GAGGAGGAAG CCGCTGCCGT GGGACTTGGG GTCCCTCCAC AGCAGGATGC TATTCTGCCA 
GAGTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Camk4 ( XM_017600850.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456339.1 Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X1, mRNA.

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CloneID	ORa59211
Clone ID Related Accession (Same CDS sequence)	XM_017600850.1
Accession Version	XM_017600850.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	calcium/calmodulin-dependent protein kinase type IV isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACTTGG TGCCTTCCAC TCCCGGAGCT CGCCTCCTTC TAGGCTGCTG GCTCTTGCCG 
AGGGCTAGGA GGAAGGCGGC GGCCAGCGGT TCCAGCTCGG GCAGCGGCGG CATCTTCCGG 
AGTCCCGCGG CGAAGATGCT CAAAGTCACG GTGCCCTCCT GTCCCTCCTC GCCCTGCTCC 
TCGGTCACCT CCAGTACTGA GAACCTCGTC CCGGATTACT GGATCGACGG CTCTAAACGG 
GATCCTCTGA GCGATTTCTT CGAGGTGGAG TCAGAGCTGG GACGGGGTGC TACATCCATT 
GTGTACAGAT GCAAACAGAA GGGGACCCAG AAGCCCTATG CTCTCAAAGT GTTAAAGAAA 
ACAGTGGACA AGAAGATCGT GAGAACTGAA ATAGGAGTTC TCCTGAGACT CTCACACCCG 
AACATCATAA AACTCAAGGA AATATTTGAA ACCCCCACAG AAATCAGCCT GGTTCTTGAG 
CTAGTCACAG GAGGAGAACT GTTTGACAGG ATTGTGGAGA AAGGCTATTA CAGTGAACGC 
GACGCGGCCG ATGCTGTGAA GCAGATCCTG GAGGCAGTTG CTTACCTGCA CGAAAATGGA 
ATCGTCCATC GCGACCTCAA ACCAGAGAAT CTTCTTTATG CAACGCCAGC CCCTGATGCA 
CCACTCAAAA TTGCTGATTT TGGACTTTCT AAAATCGTGG AACATCAAGT GCTCATGAAG 
ACGGTGTGTG GAACCCCGGG GTACTGTGCA CCTGAGATTC TCCGAGGCTG TGCCTATGGC 
CCCGAGGTGG ACATGTGGTC TGTAGGAATA ATTACCTACA TCCTACTTTG TGGATTTGAA 
CCATTCTATG ATGAGAGAGG TGATCAGTTC ATGTTCAGGA GAATTCTGAA TTGTGAATAT 
TACTTTATCT CCCCCTGGTG GGATGAAGTT TCTTTAAATG CCAAGGACTT GGTCAAGAAA 
CTCATTGTTT TGGACCCTAA GAAGCGGCTG ACTACATTCC AAGCCCTCCA ACACCCGTGG 
GTCACAGGAA AAGCAGCCAA CTTTGTCCAC ATGGATACCG CTCAGAAAAA GCTTCAAGAA 
TTCAATGCTA GGCGCAAGCT TAAGGCGGCA GTGAAGGCTG TGGTGGCCTC TTCTCGGCTG 
GGAAGTGCCA GCAGCAGTCA CACCAACATC CAAGAAAGCA ACAAAGCCAG CTCGGAGGCA 
CAGCCCGCCC AAGACGGCAA GGACAAGACA GATCCTCTGG AAAACAAAAT GCAAGCGGGG 
GACCACGAGG CAGCCAAGGC TGCAGCCGAT GAGACGATGA AGCTACAGTC CGAGGAGGTG 
GAGGAAGAGG AAGGTGTAAA AGAAGAGGAG GAAGAGGAAG AAGAGGAAGA GGAGACCTCC 
AGGATGGTAC CTCAGGAGCC AGAGGACAGG CTGGAGACAG ATGACCAGGA AATGAAGAGA 
AATTCAGAGG AGACGTTGAA GAGTGTGGAG GAAGAAATGG ACCCGAAAGC TGAGGAGGAA 
GCCGCTGCCG TGGGACTTGG GGTCCCTCCA CAGCAGGATG CTATTCTGCC AGAGTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456339.1
CDS	50..1609
Translation	MHLVPSTPGARLLLGCWLLPRARRKAAASGSSSGSGGIFRSPAAKMLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY

Target ORF information:

RefSeq Version	XM_017600850.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium/calmodulin-dependent protein kinase IV (Camk4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600850.1

ORF Insert Sequence:

ATGCACTTGG TGCCTTCCAC TCCCGGAGCT CGCCTCCTTC TAGGCTGCTG GCTCTTGCCG 
AGGGCTAGGA GGAAGGCGGC GGCCAGCGGT TCCAGCTCGG GCAGCGGCGG CATCTTCCGG 
AGTCCCGCGG CGAAGATGCT CAAAGTCACG GTGCCCTCCT GTCCCTCCTC GCCCTGCTCC 
TCGGTCACCT CCAGTACTGA GAACCTCGTC CCGGATTACT GGATCGACGG CTCTAAACGG 
GATCCTCTGA GCGATTTCTT CGAGGTGGAG TCAGAGCTGG GACGGGGTGC TACATCCATT 
GTGTACAGAT GCAAACAGAA GGGGACCCAG AAGCCCTATG CTCTCAAAGT GTTAAAGAAA 
ACAGTGGACA AGAAGATCGT GAGAACTGAA ATAGGAGTTC TCCTGAGACT CTCACACCCG 
AACATCATAA AACTCAAGGA AATATTTGAA ACCCCCACAG AAATCAGCCT GGTTCTTGAG 
CTAGTCACAG GAGGAGAACT GTTTGACAGG ATTGTGGAGA AAGGCTATTA CAGTGAACGC 
GACGCGGCCG ATGCTGTGAA GCAGATCCTG GAGGCAGTTG CTTACCTGCA CGAAAATGGA 
ATCGTCCATC GCGACCTCAA ACCAGAGAAT CTTCTTTATG CAACGCCAGC CCCTGATGCA 
CCACTCAAAA TTGCTGATTT TGGACTTTCT AAAATCGTGG AACATCAAGT GCTCATGAAG 
ACGGTGTGTG GAACCCCGGG GTACTGTGCA CCTGAGATTC TCCGAGGCTG TGCCTATGGC 
CCCGAGGTGG ACATGTGGTC TGTAGGAATA ATTACCTACA TCCTACTTTG TGGATTTGAA 
CCATTCTATG ATGAGAGAGG TGATCAGTTC ATGTTCAGGA GAATTCTGAA TTGTGAATAT 
TACTTTATCT CCCCCTGGTG GGATGAAGTT TCTTTAAATG CCAAGGACTT GGTCAAGAAA 
CTCATTGTTT TGGACCCTAA GAAGCGGCTG ACTACATTCC AAGCCCTCCA ACACCCGTGG 
GTCACAGGAA AAGCAGCCAA CTTTGTCCAC ATGGATACCG CTCAGAAAAA GCTTCAAGAA 
TTCAATGCTA GGCGCAAGCT TAAGGCGGCA GTGAAGGCTG TGGTGGCCTC TTCTCGGCTG 
GGAAGTGCCA GCAGCAGTCA CACCAACATC CAAGAAAGCA ACAAAGCCAG CTCGGAGGCA 
CAGCCCGCCC AAGACGGCAA GGACAAGACA GATCCTCTGG AAAACAAAAT GCAAGCGGGG 
GACCACGAGG CAGCCAAGGC TGCAGCCGAT GAGACGATGA AGCTACAGTC CGAGGAGGTG 
GAGGAAGAGG AAGGTGTAAA AGAAGAGGAG GAAGAGGAAG AAGAGGAAGA GGAGACCTCC 
AGGATGGTAC CTCAGGAGCC AGAGGACAGG CTGGAGACAG ATGACCAGGA AATGAAGAGA 
AATTCAGAGG AGACGTTGAA GAGTGTGGAG GAAGAAATGG ACCCGAAAGC TGAGGAGGAA 
GCCGCTGCCG TGGGACTTGG GGTCCCTCCA CAGCAGGATG CTATTCTGCC AGAGTACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

All for One But Not One for All: Excitatory Synaptic Scaling and Intrinsic Excitability Are Coregulated by CaMKIV, Whereas Inhibitory Synaptic Scaling Is Under Independent Control.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(28)6778-6785(2017 07)
Joseph A,Turrigiano GG

Inhibition of CaMKIV relieves streptozotocin-induced diabetic neuropathic pain through regulation of HMGB1.
BMC anesthesiology16(1)27(2016 05)
Zhao X,Shen L,Xu L,Wang Z,Ma C,Huang Y

Late maternal hypothyroidism alters the expression of Camk4 in neocortical subplate neurons: a comparison with Nurr1 labeling.
Cerebral cortex (New York, N.Y. : 1991)24(10)2694-706(2014 Oct)
Navarro D,Alvarado M,Morte B,Berbel D,Sesma J,Pacheco P,Morreale de Escobar G,Bernal J,Berbel P

IB4-binding sensory neurons in the adult rat express a novel 3' UTR-extended isoform of CaMK4 that is associated with its localization to axons.
The Journal of comparative neurology522(2)308-36(2014 Feb)
Harrison BJ,Flight RM,Gomes C,Venkat G,Ellis SR,Sankar U,Twiss JL,Rouchka EC,Petruska JC

Calcium/calmodulin-dependent protein kinase IV mediates distinct features of basal and activity-dependent dendrite complexity.
Neuroscience199548-62(2011 Dec)
Nagendran T,Hardy LR

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Camk4 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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