Cant1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cant1
Entrez Gene ID	246272
Full Name	calcium activated nucleotidase 1
Synonyms	srapy
General protein information	Preferred Names calcium activated nucleotidase 1 Names soluble calcium-activated nucleotidase 1 SCAN-1 apyrase homolog ectonucleoside triphosphate diphosphohydrolase 8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.3
Summary	hydrolyzes nucleoside 5'-diphosphates in the order UDP >GDP = IDP >>>CDP but not ADP, may be involved in glycosylation reactions related to quality control in the endoplasmic reticulum [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_144754.2	NP_653355.1	soluble calcium-activated nucleotidase 1
XM_006247789.3	XP_006247851.1	soluble calcium-activated nucleotidase 1 isoform X1
XM_006247790.1	XP_006247852.1	soluble calcium-activated nucleotidase 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cant1	NP_653355.1
Bos taurus (cattle)	CANT1	XP_002696200.2
Mus musculus (house mouse)	Cant1	NP_001020788.1
Danio rerio (zebrafish)	cant1a	NP_999908.1
Homo sapiens (human)	CANT1	NP_001153244.1
Pan troglodytes (chimpanzee)	CANT1	XP_001158629.1
Caenorhabditis elegans (roundworm)	apy-1	NP_509283.1
Xenopus tropicalis (tropical clawed frog)	cant1	NP_988940.1
Drosophila melanogaster (fruit fly)	CG5276	NP_650074.1
Macaca mulatta (Rhesus monkey)	CANT1	XP_001109215.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001217	XP_321938.3

Gene Ontology
Bibliography

Related articles in PubMed

Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Nizon M, Huber C, De Leonardis F, Merrina R, Forlino A, Fradin M, Tuysuz B, Abu-Libdeh BY, Alanay Y, Albrecht B, Al-Gazali L, Basaran SY, Clayton-Smith J, Désir J, Gill H, Greally MT, Koparir E, van Maarle MC, MacKay S, Mortier G, Morton J, Sillence D, Vilain C, Young I, Zerres K, Le Merrer M, Munnich A, Le Goff C, Rossi A, Cormier-Daire V
Human mutation33(8)1261-6(2012 Aug)

Histochemical detection of ischemia-like alterations induced in kidney tissue in vitro--different sensitivity to oxidant stress of glomerular ENTPD1 versus E5NT.
Vlaar AP, van Son WJ, Bakker WW
Nephron. Physiology111(1)p1-8(2009)

Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
Yang M, Horii K, Herr AB, Kirley TL
The Journal of biological chemistry281(38)28307-17(2006 Sep)

Apyrase and 5'-nucleotidase activities in synaptosomes from the cerebral cortex of rats experimentally demyelinated with ethidium bromide and treated with interferon-beta.
Spanevello RM, Mazzanti CM, Kaizer R, Zanin R, Cargnelutti D, Hannel L, Côrrea M, Mazzanti A, Festugatto R, Graça D, Schetinger MR, Morsch VM
Neurochemical research31(4)455-62(2006 Apr)

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S
Oncogene22(21)3307-18(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cant1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cant1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02500	NM_144754.2 Latest version!	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa02500	XM_006247789.3 Latest version!	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa02500	XM_006247790.1 Latest version!	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cant1 ( NM_144754.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_653355.1 Rattus norvegicus calcium activated nucleotidase 1 (Cant1), mRNA.

Price & Availability↑

CloneID	ORa02500
Clone ID Related Accession (Same CDS sequence)	NM_144754.2 , XM_006247789.3 , XM_006247790.1
Accession Version	NM_144754.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	soluble calcium-activated nucleotidase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097279.1. On Jun 12, 2005 this sequence version replaced NM_144754.1. ##Evidence-Data-START## Transcript exon combination :: BC097279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653355.1
CDS	76..1287
Translation	MPIQPFDQREWNEPMHSLRISVGGLPVLASMTKATDPRFRPRWRVILTSFVGAALLWLLYSHHQTPVSGRPPIHNAHNWRLRQERISQYNDTYPLSPPQRTPGGIRYRIAVIADLDTGSKAQEENTWFSYLKKGYLTLSDSGDRVSVEWDKDRGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVIYQIEGTKAVPWVILSDGDGAVEKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGHRGSVEHENWVSSYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASHERYSEREDERKGSNLLLSAAQDFRDISVRQVGALVPTHGFSSFKFIPNTDDQIIVALKSEEDNGRIATYVMAFTLDGRFLLPETKIGSVKYEGIEFI

Target ORF information:

RefSeq Version	NM_144754.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144754.2

ORF Insert Sequence:

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cant1 ( XM_006247789.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247851.1 Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa02500
Clone ID Related Accession (Same CDS sequence)	NM_144754.2 , XM_006247789.3 , XM_006247790.1
Accession Version	XM_006247789.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	soluble calcium-activated nucleotidase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247789.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247851.1
CDS	595..1806
Translation	MPIQPFDQREWNEPMHSLRISVGGLPVLASMTKATDPRFRPRWRVILTSFVGAALLWLLYSHHQTPVSGRPPIHNAHNWRLRQERISQYNDTYPLSPPQRTPGGIRYRIAVIADLDTGSKAQEENTWFSYLKKGYLTLSDSGDRVSVEWDKDRGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVIYQIEGTKAVPWVILSDGDGAVEKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGHRGSVEHENWVSSYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASHERYSEREDERKGSNLLLSAAQDFRDISVRQVGALVPTHGFSSFKFIPNTDDQIIVALKSEEDNGRIATYVMAFTLDGRFLLPETKIGSVKYEGIEFI

Target ORF information:

RefSeq Version	XM_006247789.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247789.3

ORF Insert Sequence:

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cant1 ( XM_006247790.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247852.1 Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02500
Clone ID Related Accession (Same CDS sequence)	NM_144754.2 , XM_006247789.3 , XM_006247790.1
Accession Version	XM_006247790.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	soluble calcium-activated nucleotidase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247852.1
CDS	146..1357
Translation	MPIQPFDQREWNEPMHSLRISVGGLPVLASMTKATDPRFRPRWRVILTSFVGAALLWLLYSHHQTPVSGRPPIHNAHNWRLRQERISQYNDTYPLSPPQRTPGGIRYRIAVIADLDTGSKAQEENTWFSYLKKGYLTLSDSGDRVSVEWDKDRGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVIYQIEGTKAVPWVILSDGDGAVEKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGHRGSVEHENWVSSYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASHERYSEREDERKGSNLLLSAAQDFRDISVRQVGALVPTHGFSSFKFIPNTDDQIIVALKSEEDNGRIATYVMAFTLDGRFLLPETKIGSVKYEGIEFI

Target ORF information:

RefSeq Version	XM_006247790.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium activated nucleotidase 1 (Cant1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247790.1

ORF Insert Sequence:

ATGCCCATCC AGCCCTTTGA CCAGCGGGAA TGGAATGAGC CTATGCACTC CCTCCGGATC 
AGTGTAGGGG GCCTTCCAGT GCTGGCATCC ATGACCAAGG CCACGGACCC TCGCTTCCGT 
CCCCGCTGGA GGGTGATTCT GACGTCCTTT GTGGGTGCTG CCCTCCTCTG GCTGCTGTAT 
TCCCACCATC AGACCCCAGT ATCGGGCAGG CCCCCCATCC ACAACGCACA CAACTGGAGG 
CTCAGGCAGG AGCGCATCTC TCAATACAAT GACACCTACC CCCTATCACC CCCACAGAGG 
ACTCCAGGTG GGATTCGGTA CCGAATTGCA GTCATTGCTG ACTTGGACAC GGGGTCCAAG 
GCCCAGGAGG AGAACACTTG GTTTAGTTAC CTTAAGAAAG GCTACCTGAC CCTGTCGGAC 
AGTGGGGACA GGGTCAGTGT GGAGTGGGAT AAAGACCGTG GAGTCCTGGA GTCCCACCTG 
GCAGAAAAGG GGCGGGGCAT GGAGCTCTCG GACCTGATCG TCTTCAACGG GAAACTCTAC 
TCTGTGGATG ACCGCACGGG GGTCATCTAC CAGATCGAAG GTACCAAAGC AGTGCCCTGG 
GTGATCCTTT CTGATGGCGA TGGAGCTGTG GAGAAGGGCT TCAAAGCGGA ATGGCTGGCT 
GTGAAGGACG AGCATCTGTA CGTGGGTGGC CTGGGCAAGG AGTGGACGAC CACAACGGGG 
GAGGTGGTGA ACGAGAACCC TGAGTGGGTG AAGGTGGTGG GCCACAGGGG CAGTGTGGAA 
CACGAGAACT GGGTGTCCAG CTACAATGCC CTGAGAGCTG CCGCAGGGAT CCAACCGCCA 
GGCTACCTCA TTCATGAGTC CGCCTGCTGG AGCGACACAC TGCAGCGCTG GTTCTTCCTG 
CCACGACGGG CGAGCCACGA GCGCTACAGC GAAAGGGAGG ACGAGCGAAA GGGCAGCAAC 
CTGCTGCTGA GCGCAGCCCA GGACTTCAGG GACATCTCTG TGAGGCAAGT GGGGGCGCTG 
GTCCCCACCC ATGGCTTCTC ATCCTTCAAG TTCATCCCCA ACACGGATGA CCAGATCATC 
GTGGCTCTCA AGTCAGAAGA GGACAATGGC AGGATTGCCA CCTATGTCAT GGCCTTTACG 
CTGGACGGCC GCTTCCTGCT TCCAGAGACC AAGATCGGCA GTGTGAAGTA TGAAGGAATA 
GAATTCATCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Human mutation33(8)1261-6(2012 Aug)
Nizon M,Huber C,De Leonardis F,Merrina R,Forlino A,Fradin M,Tuysuz B,Abu-Libdeh BY,Alanay Y,Albrecht B,Al-Gazali L,Basaran SY,Clayton-Smith J,Désir J,Gill H,Greally MT,Koparir E,van Maarle MC,MacKay S,Mortier G,Morton J,Sillence D,Vilain C,Young I,Zerres K,Le Merrer M,Munnich A,Le Goff C,Rossi A,Cormier-Daire V

Histochemical detection of ischemia-like alterations induced in kidney tissue in vitro--different sensitivity to oxidant stress of glomerular ENTPD1 versus E5NT.
Nephron. Physiology111(1)p1-8(2009)
Vlaar AP,van Son WJ,Bakker WW

Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
The Journal of biological chemistry281(38)28307-17(2006 Sep)
Yang M,Horii K,Herr AB,Kirley TL

Apyrase and 5'-nucleotidase activities in synaptosomes from the cerebral cortex of rats experimentally demyelinated with ethidium bromide and treated with interferon-beta.
Neurochemical research31(4)455-62(2006 Apr)
Spanevello RM,Mazzanti CM,Kaizer R,Zanin R,Cargnelutti D,Hannel L,Côrrea M,Mazzanti A,Festugatto R,Graça D,Schetinger MR,Morsch VM

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
Oncogene22(21)3307-18(2003 May)
Matsuda A,Suzuki Y,Honda G,Muramatsu S,Matsuzaki O,Nagano Y,Doi T,Shimotohno K,Harada T,Nishida E,Hayashi H,Sugano S

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Cant1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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ORF Insert Sequence:

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