Clk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clk3
Entrez Gene ID	171305
Full Name	CDC-like kinase 3
General protein information	Preferred Names CDC-like kinase 3 Names dual specificity protein kinase CLK3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24
Summary	has autophosphorylation activity; may play a role in testicular function [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134340.1	NP_599167.1	dual specificity protein kinase CLK3
XM_006243146.3	XP_006243208.1	dual specificity protein kinase CLK3 isoform X1
XM_008766202.1	XP_008764424.1	dual specificity protein kinase CLK3 isoform X2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Clk3	NP_031739.3
Rattus norvegicus (Norway rat)	Clk3	NP_599167.1
Gallus gallus (chicken)	CLK3	NP_001012542.2
Homo sapiens (human)	CLK3	NP_001123500.1
Canis lupus familiaris (dog)	CLK3	XP_867057.2
Xenopus tropicalis (tropical clawed frog)	clk3	NP_001011462.1
Macaca mulatta (Rhesus monkey)	CLK3	XP_001100690.1
Pan troglodytes (chimpanzee)	CLK3	NP_001233438.1
Bos taurus (cattle)	CLK3	NP_001029420.1

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing.
Duncan PI, Stojdl DF, Marius RM, Scheit KH, Bell JC
Experimental cell research241(2)300-8(1998 Jun)

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.
Nayler O, Stamm S, Ullrich A
The Biochemical journal326 ( Pt 3)693-700(1997 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Clk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01134	NM_134340.1 Latest version!	Rattus norvegicus CDC-like kinase 3 (Clk3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa44297	XM_008766202.1 Latest version!	Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa31214	XM_006243146.3 Latest version!	Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clk3 ( NM_134340.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599167.1 Rattus norvegicus CDC-like kinase 3 (Clk3), mRNA.

Price & Availability↑

CloneID	ORa01134
Clone ID Related Accession (Same CDS sequence)	NM_134340.1
Accession Version	NM_134340.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein kinase CLK3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X94351.1. ##Evidence-Data-START## Transcript exon combination :: X94351.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCATCACT GTAAGCGATA CCGTTCCCCA GAGCCAGACC CATACCTGAG CTACCGCTGG 
AAGAGGAGGC GGTCTTACAG TCGGGAGCAT GAAGGTCGAC TACGATACCC ATCCCGAAGG 
GAGCCTCCCC CACGGAGATC AAGGTCCAGA AGCCATGATC GTATACCCTA CCAGAGGAGG 
TACCGGGAAC ACCGAGACAG CGATACATAT CGGTGTGAAG AGCGGAGCCC ATCCTTTGGA 
GAGGACTGCT ATGGGTCTTC ACGTTCTCGA CATCGGAGAC GGTCACGAGA GAGGGGGCCG 
TACCGTACAC GCAAGCATGC CCACCACTGT CACAAACGTC GTACCAGGTC TTGTAGCAGC 
GCCTCCTCGA GAAGCCAACA GAGCAGTAAG CGCAGCAGCC GGAGTGTGGA AGATGACAAG 
GAGGGCCACC TGGTGTGCCG GATCGGCGAT TGGCTCCAAG AGCGATATGA GATCGTGGGG 
AACCTGGGTG AAGGCACCTT TGGCAAGGTG GTGGAGTGCT TGGACCATGC CAGAGGGAAG 
TCACAGGTTG CCCTGAAGAT CATCCGTAAT GTGGGCAAGT ACCGGGAAGC TGCTCGTCTA 
GAAATTAATG TTCTCAAGAA AATCAAGGAG AAAGACAAAG AAAATAAGTT CCTTTGTGTC 
CTGATGTCTG ACTGGTTCAA CTTCCATGGT CATATGTGTA TCGCCTTTGA GCTCCTGGGC 
AAGAACACCT TTGAGTTCCT GAAGGAGAAC AACTTCCAGC CTTATCCCCT ACCACATGTC 
CGGCACATGG CCTACCAGCT CTGTCATGCC CTTAGATTTC TACATGAGAA CCAGCTGACC 
CACACAGACT TGAAGCCAGA GAACATCTTG TTTGTGAATT CTGAGTTTGA AACCCTCTAC 
AATGAGCACA AGAGCTGCGA GGAGAAGTCA GTGAAGAACA CCAGCATCCG AGTGGCAGAC 
TTTGGCAGTG CCACATTTGA CCATGAACAT CACACCACCA TTGTCGCCAC CCGGCATTAC 
CGCCCACCTG AGGTGATCCT TGAGCTGGGC TGGGCACAGC CCTGTGATGT CTGGAGTATC 
GGCTGCATTC TCTTTGAGTA CTACCGTGGC TTTACACTCT TCCAGACCCA TGAAAACAGA 
GAACACTTGG TTATGATGGA GAAGATCCTA GGACCCATCC CATCACACAT GATCCACCGT 
ACCAGGAAGC AGAAGTATTT CTACAAAGGG GGCCTGGTTT GGGATGAGAA CAGCTCTGAC 
GGGCGGTATG TGAAGGAGAA CTGCAAACCT CTGAAGAGTT ACATGCTCCA GGACTCCCTG 
GAGCATGTGC AGCTGTTTGA CCTGATGAGG AGGATGTTAG AGTTCGACCC GTCTCAGCGC 
ATCACACTGG CAGAAGCTTT GCTGCACCCC TTCTTTGCTG GCCTGACCCC TGAGGAGCGG 
TCCTTCCACA GCAGCCGTAA CCCCAGCAGA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599167.1
CDS	57..1529
Translation	MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRIPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPSQRITLAEALLHPFFAGLTPEERSFHSSRNPSR

Target ORF information:

RefSeq Version	NM_134340.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDC-like kinase 3 (Clk3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134340.1

ORF Insert Sequence:

ATGCATCACT GTAAGCGATA CCGTTCCCCA GAGCCAGACC CATACCTGAG CTACCGCTGG 
AAGAGGAGGC GGTCTTACAG TCGGGAGCAT GAAGGTCGAC TACGATACCC ATCCCGAAGG 
GAGCCTCCCC CACGGAGATC AAGGTCCAGA AGCCATGATC GTATACCCTA CCAGAGGAGG 
TACCGGGAAC ACCGAGACAG CGATACATAT CGGTGTGAAG AGCGGAGCCC ATCCTTTGGA 
GAGGACTGCT ATGGGTCTTC ACGTTCTCGA CATCGGAGAC GGTCACGAGA GAGGGGGCCG 
TACCGTACAC GCAAGCATGC CCACCACTGT CACAAACGTC GTACCAGGTC TTGTAGCAGC 
GCCTCCTCGA GAAGCCAACA GAGCAGTAAG CGCAGCAGCC GGAGTGTGGA AGATGACAAG 
GAGGGCCACC TGGTGTGCCG GATCGGCGAT TGGCTCCAAG AGCGATATGA GATCGTGGGG 
AACCTGGGTG AAGGCACCTT TGGCAAGGTG GTGGAGTGCT TGGACCATGC CAGAGGGAAG 
TCACAGGTTG CCCTGAAGAT CATCCGTAAT GTGGGCAAGT ACCGGGAAGC TGCTCGTCTA 
GAAATTAATG TTCTCAAGAA AATCAAGGAG AAAGACAAAG AAAATAAGTT CCTTTGTGTC 
CTGATGTCTG ACTGGTTCAA CTTCCATGGT CATATGTGTA TCGCCTTTGA GCTCCTGGGC 
AAGAACACCT TTGAGTTCCT GAAGGAGAAC AACTTCCAGC CTTATCCCCT ACCACATGTC 
CGGCACATGG CCTACCAGCT CTGTCATGCC CTTAGATTTC TACATGAGAA CCAGCTGACC 
CACACAGACT TGAAGCCAGA GAACATCTTG TTTGTGAATT CTGAGTTTGA AACCCTCTAC 
AATGAGCACA AGAGCTGCGA GGAGAAGTCA GTGAAGAACA CCAGCATCCG AGTGGCAGAC 
TTTGGCAGTG CCACATTTGA CCATGAACAT CACACCACCA TTGTCGCCAC CCGGCATTAC 
CGCCCACCTG AGGTGATCCT TGAGCTGGGC TGGGCACAGC CCTGTGATGT CTGGAGTATC 
GGCTGCATTC TCTTTGAGTA CTACCGTGGC TTTACACTCT TCCAGACCCA TGAAAACAGA 
GAACACTTGG TTATGATGGA GAAGATCCTA GGACCCATCC CATCACACAT GATCCACCGT 
ACCAGGAAGC AGAAGTATTT CTACAAAGGG GGCCTGGTTT GGGATGAGAA CAGCTCTGAC 
GGGCGGTATG TGAAGGAGAA CTGCAAACCT CTGAAGAGTT ACATGCTCCA GGACTCCCTG 
GAGCATGTGC AGCTGTTTGA CCTGATGAGG AGGATGTTAG AGTTCGACCC GTCTCAGCGC 
ATCACACTGG CAGAAGCTTT GCTGCACCCC TTCTTTGCTG GCCTGACCCC TGAGGAGCGG 
TCCTTCCACA GCAGCCGTAA CCCCAGCAGA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clk3 ( XM_008766202.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008764424.1 Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa44297
Clone ID Related Accession (Same CDS sequence)	XM_008766202.1
Accession Version	XM_008766202.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein kinase CLK3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGACT GGTTCAACTT CCATGGTCAT ATGTGTATCG CCTTTGAGCT CCTGGGCAAG 
AACACCTTTG AGTTCCTGAA GGAGAACAAC TTCCAGCCTT ATCCCCTACC ACATGTCCGG 
CACATGGCCT ACCAGCTCTG TCATGCCCTT AGATTTCTAC ATGAGAACCA GCTGACCCAC 
ACAGACTTGA AGCCAGAGAA CATCTTGTTT GTGAATTCTG AGTTTGAAAC CCTCTACAAT 
GAGCACAAGA GCTGCGAGGA GAAGTCAGTG AAGAACACCA GCATCCGAGT GGCAGACTTT 
GGCAGTGCCA CATTTGACCA TGAACATCAC ACCACCATTG TCGCCACCCG GCATTACCGC 
CCACCTGAGG TGATCCTTGA GCTGGGCTGG GCACAGCCCT GTGATGTCTG GAGTATCGGC 
TGCATTCTCT TTGAGTACTA CCGTGGCTTT ACACTCTTCC AGACCCATGA AAACAGAGAA 
CACTTGGTTA TGATGGAGAA GATCCTAGGA CCCATCCCAT CACACATGAT CCACCGTACC 
AGGAAGCAGA AGTATTTCTA CAAAGGGGGC CTGGTTTGGG ATGAGAACAG CTCTGACGGG 
CGGTATGTGA AGGAGAACTG CAAACCTCTG AAGAGTTACA TGCTCCAGGA CTCCCTGGAG 
CATGTGCAGC TGTTTGACCT GATGAGGAGG ATGTTAGAGT TCGACCCTGC TCAGCGCATC 
ACACTGGCAG AAGCTTTGCT GCACCCCTTC TTTGCTGGCC TGACCCCTGA GGAGCGGTCC 
TTCCACAGCA GCCGTAACCC CAGCAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008764424.1
CDS	414..1223
Translation	MSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR

Target ORF information:

RefSeq Version	XM_008766202.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008766202.1

ORF Insert Sequence:

ATGTCTGACT GGTTCAACTT CCATGGTCAT ATGTGTATCG CCTTTGAGCT CCTGGGCAAG 
AACACCTTTG AGTTCCTGAA GGAGAACAAC TTCCAGCCTT ATCCCCTACC ACATGTCCGG 
CACATGGCCT ACCAGCTCTG TCATGCCCTT AGATTTCTAC ATGAGAACCA GCTGACCCAC 
ACAGACTTGA AGCCAGAGAA CATCTTGTTT GTGAATTCTG AGTTTGAAAC CCTCTACAAT 
GAGCACAAGA GCTGCGAGGA GAAGTCAGTG AAGAACACCA GCATCCGAGT GGCAGACTTT 
GGCAGTGCCA CATTTGACCA TGAACATCAC ACCACCATTG TCGCCACCCG GCATTACCGC 
CCACCTGAGG TGATCCTTGA GCTGGGCTGG GCACAGCCCT GTGATGTCTG GAGTATCGGC 
TGCATTCTCT TTGAGTACTA CCGTGGCTTT ACACTCTTCC AGACCCATGA AAACAGAGAA 
CACTTGGTTA TGATGGAGAA GATCCTAGGA CCCATCCCAT CACACATGAT CCACCGTACC 
AGGAAGCAGA AGTATTTCTA CAAAGGGGGC CTGGTTTGGG ATGAGAACAG CTCTGACGGG 
CGGTATGTGA AGGAGAACTG CAAACCTCTG AAGAGTTACA TGCTCCAGGA CTCCCTGGAG 
CATGTGCAGC TGTTTGACCT GATGAGGAGG ATGTTAGAGT TCGACCCTGC TCAGCGCATC 
ACACTGGCAG AAGCTTTGCT GCACCCCTTC TTTGCTGGCC TGACCCCTGA GGAGCGGTCC 
TTCCACAGCA GCCGTAACCC CAGCAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clk3 ( XM_006243146.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243208.1 Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa31214
Clone ID Related Accession (Same CDS sequence)	XM_006243146.3
Accession Version	XM_006243146.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein kinase CLK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243146.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGTCC TCTCCTCGCG CAGGAAGAGG CTGGCGAGCA TCGCCGGGCC GCGGCGGGGA 
AGCGGCCCCA GCCTGGCAGT CCGGTGGGTT CCTCCTTTAG GCCTAGAGCT GGCCTCAGAC 
CGCGGTCGTG GCCGCGCACA GATGCGACCT CGGGGGCCTA CGTGCACCAC TACACGGAGA 
GGGGCAGGCC GCCGCCCGAG GATGCTCCCC GGACCTCCCG GAAGAGACCT CCAGCGTTGC 
GGCCCGGACC CTGGCGGGGC AAGCCAGTCC CCCAGAGTCT GCGAGTTGGC GGCTAGAGCG 
GCCAGGCCTC TGGGCCGGGT CGAGCCCGGG CCGCCGACGG CTGCGTCACG CGAGGGGGCG 
GTGCTGCCAC GGGCGGAGGC CAGAGCCGGA AGCGGAAGAG GCGCTCGGAG TGGGGAGTGG 
GGCCTAGCCG CAGCCGGAGC CTGGGAGACG ATGCATCACT GTAAGCGATA CCGTTCCCCA 
GAGCCAGACC CATACCTGAG CTACCGCTGG AAGAGGAGGC GGTCTTACAG TCGGGAGCAT 
GAAGGTCGAC TACGATACCC ATCCCGAAGG GAGCCTCCCC CACGGAGATC AAGGTCCAGA 
AGCCATGATC GTATACCCTA CCAGAGGAGG TACCGGGAAC ACCGAGACAG CGATACATAT 
CGGTGTGAAG AGCGGAGCCC ATCCTTTGGA GAGGACTGCT ATGGGTCTTC ACGTTCTCGA 
CATCGGAGAC GGTCACGAGA GAGGGGGCCG TACCGTACCC GCAAGCATGC CCACCACTGT 
CACAAACGTC GTACCAGGTC TTGTAGCAGC GCCTCCTCGA GAAGCCAACA GAGCAGTAAG 
CGCAGCAGCC GGAGTGTGGA AGATGACAAG GAGGGCCACC TGGTGTGCCG GATCGGCGAT 
TGGCTCCAAG AGCGATATGA GATCGTGGGG AACCTGGGTG AAGGCACCTT TGGCAAGGTG 
GTGGAGTGCT TGGACCATGC CAGAGGGAAG TCACAGGTTG CCCTGAAGAT CATCCGTAAT 
GTGGGCAAGT ACCGGGAAGC TGCTCGTCTA GAAATTAATG TTCTCAAGAA AATCAAGGAG 
AAAGACAAAG AAAATAAGTT CCTTTGTGTC CTGATGTCTG ACTGGTTCAA CTTCCATGGT 
CATATGTGTA TCGCCTTTGA GCTCCTGGGC AAGAACACCT TTGAGTTCCT GAAGGAGAAC 
AACTTCCAGC CTTATCCCCT ACCACATGTC CGGCACATGG CCTACCAGCT CTGTCATGCC 
CTTAGATTTC TACATGAGAA CCAGCTGACC CACACAGACT TGAAGCCAGA GAACATCTTG 
TTTGTGAATT CTGAGTTTGA AACCCTCTAC AATGAGCACA AGAGCTGCGA GGAGAAGTCA 
GTGAAGAACA CCAGCATCCG AGTGGCAGAC TTTGGCAGTG CCACATTTGA CCATGAACAT 
CACACCACCA TTGTCGCCAC CCGGCATTAC CGCCCACCTG AGGTGATCCT TGAGCTGGGC 
TGGGCACAGC CCTGTGATGT CTGGAGTATC GGCTGCATTC TCTTTGAGTA CTACCGTGGC 
TTTACACTCT TCCAGACCCA TGAAAACAGA GAACACTTGG TTATGATGGA GAAGATCCTA 
GGACCCATCC CATCACACAT GATCCACCGT ACCAGGAAGC AGAAGTATTT CTACAAAGGG 
GGCCTGGTTT GGGATGAGAA CAGCTCTGAC GGGCGGTATG TGAAGGAGAA CTGCAAACCT 
CTGAAGAGTT ACATGCTCCA GGACTCCCTG GAGCATGTGC AGCTGTTTGA CCTGATGAGG 
AGGATGTTAG AGTTCGACCC TGCTCAGCGC ATCACACTGG CAGAAGCTTT GCTGCACCCC 
TTCTTTGCTG GCCTGACCCC TGAGGAGCGG TCCTTCCACA GCAGCCGTAA CCCCAGCAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243208.1
CDS	559..2481
Translation	MPVLSSRRKRLASIAGPRRGSGPSLAVRWVPPLGLELASDRGRGRAQMRPRGPTCTTTRRGAGRRPRMLPGPPGRDLQRCGPDPGGASQSPRVCELAARAARPLGRVEPGPPTAASREGAVLPRAEARAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRIPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR

Target ORF information:

RefSeq Version	XM_006243146.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CDC-like kinase 3 (Clk3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243146.3

ORF Insert Sequence:

ATGCCGGTCC TCTCCTCGCG CAGGAAGAGG CTGGCGAGCA TCGCCGGGCC GCGGCGGGGA 
AGCGGCCCCA GCCTGGCAGT CCGGTGGGTT CCTCCTTTAG GCCTAGAGCT GGCCTCAGAC 
CGCGGTCGTG GCCGCGCACA GATGCGACCT CGGGGGCCTA CGTGCACCAC TACACGGAGA 
GGGGCAGGCC GCCGCCCGAG GATGCTCCCC GGACCTCCCG GAAGAGACCT CCAGCGTTGC 
GGCCCGGACC CTGGCGGGGC AAGCCAGTCC CCCAGAGTCT GCGAGTTGGC GGCTAGAGCG 
GCCAGGCCTC TGGGCCGGGT CGAGCCCGGG CCGCCGACGG CTGCGTCACG CGAGGGGGCG 
GTGCTGCCAC GGGCGGAGGC CAGAGCCGGA AGCGGAAGAG GCGCTCGGAG TGGGGAGTGG 
GGCCTAGCCG CAGCCGGAGC CTGGGAGACG ATGCATCACT GTAAGCGATA CCGTTCCCCA 
GAGCCAGACC CATACCTGAG CTACCGCTGG AAGAGGAGGC GGTCTTACAG TCGGGAGCAT 
GAAGGTCGAC TACGATACCC ATCCCGAAGG GAGCCTCCCC CACGGAGATC AAGGTCCAGA 
AGCCATGATC GTATACCCTA CCAGAGGAGG TACCGGGAAC ACCGAGACAG CGATACATAT 
CGGTGTGAAG AGCGGAGCCC ATCCTTTGGA GAGGACTGCT ATGGGTCTTC ACGTTCTCGA 
CATCGGAGAC GGTCACGAGA GAGGGGGCCG TACCGTACCC GCAAGCATGC CCACCACTGT 
CACAAACGTC GTACCAGGTC TTGTAGCAGC GCCTCCTCGA GAAGCCAACA GAGCAGTAAG 
CGCAGCAGCC GGAGTGTGGA AGATGACAAG GAGGGCCACC TGGTGTGCCG GATCGGCGAT 
TGGCTCCAAG AGCGATATGA GATCGTGGGG AACCTGGGTG AAGGCACCTT TGGCAAGGTG 
GTGGAGTGCT TGGACCATGC CAGAGGGAAG TCACAGGTTG CCCTGAAGAT CATCCGTAAT 
GTGGGCAAGT ACCGGGAAGC TGCTCGTCTA GAAATTAATG TTCTCAAGAA AATCAAGGAG 
AAAGACAAAG AAAATAAGTT CCTTTGTGTC CTGATGTCTG ACTGGTTCAA CTTCCATGGT 
CATATGTGTA TCGCCTTTGA GCTCCTGGGC AAGAACACCT TTGAGTTCCT GAAGGAGAAC 
AACTTCCAGC CTTATCCCCT ACCACATGTC CGGCACATGG CCTACCAGCT CTGTCATGCC 
CTTAGATTTC TACATGAGAA CCAGCTGACC CACACAGACT TGAAGCCAGA GAACATCTTG 
TTTGTGAATT CTGAGTTTGA AACCCTCTAC AATGAGCACA AGAGCTGCGA GGAGAAGTCA 
GTGAAGAACA CCAGCATCCG AGTGGCAGAC TTTGGCAGTG CCACATTTGA CCATGAACAT 
CACACCACCA TTGTCGCCAC CCGGCATTAC CGCCCACCTG AGGTGATCCT TGAGCTGGGC 
TGGGCACAGC CCTGTGATGT CTGGAGTATC GGCTGCATTC TCTTTGAGTA CTACCGTGGC 
TTTACACTCT TCCAGACCCA TGAAAACAGA GAACACTTGG TTATGATGGA GAAGATCCTA 
GGACCCATCC CATCACACAT GATCCACCGT ACCAGGAAGC AGAAGTATTT CTACAAAGGG 
GGCCTGGTTT GGGATGAGAA CAGCTCTGAC GGGCGGTATG TGAAGGAGAA CTGCAAACCT 
CTGAAGAGTT ACATGCTCCA GGACTCCCTG GAGCATGTGC AGCTGTTTGA CCTGATGAGG 
AGGATGTTAG AGTTCGACCC TGCTCAGCGC ATCACACTGG CAGAAGCTTT GCTGCACCCC 
TTCTTTGCTG GCCTGACCCC TGAGGAGCGG TCCTTCCACA GCAGCCGTAA CCCCAGCAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing.
Experimental cell research241(2)300-8(1998 Jun)
Duncan PI,Stojdl DF,Marius RM,Scheit KH,Bell JC

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.
The Biochemical journal326 ( Pt 3)693-700(1997 Sep)
Nayler O,Stamm S,Ullrich A

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Clk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

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