Pank4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pank4
Entrez Gene ID	171053
Full Name	pantothenate kinase 4
Synonyms	Fang1
General protein information	Preferred Names pantothenate kinase 4 Names pantothenate kinase 4 hypothetical protein Fang1 pantothenic acid kinase 4 rPanK4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	human homolog is a member of the pantothenate kinase family; may play a role in coenzyme A biosynthesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133531.2	NP_598215.1	4'-phosphopantetheine phosphatase

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os09g0533100	NP_001063766.1
Eremothecium gossypii	AGOS_AFR729C	NP_986277.2
Homo sapiens (human)	PANK4	NP_060686.1
Rattus norvegicus (Norway rat)	Pank4	NP_598215.1
Caenorhabditis elegans (roundworm)	pnk-4	NP_508866.1
Kluyveromyces lactis	KLLA0C00869g	XP_452233.1
Neurospora crassa	NCU03154	XP_964560.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010073	XP_319230.4
Canis lupus familiaris (dog)	PANK4	XP_536718.2
Bos taurus (cattle)	PANK4	NP_001076898.1
Gallus gallus (chicken)	PANK4	NP_001231841.1
Xenopus tropicalis (tropical clawed frog)	pank4	NP_001120490.2
Pan troglodytes (chimpanzee)	PANK4	XP_524846.3
Mus musculus (house mouse)	Pank4	NP_766578.2
Saccharomyces cerevisiae (baker's yeast)	CAB1	NP_010820.3
Macaca mulatta (Rhesus monkey)	PANK4	XP_001086116.2
Danio rerio (zebrafish)	pank4	NP_956809.1
Drosophila melanogaster (fruit fly)	CG5828	NP_001260085.1
Magnaporthe oryzae (rice blast fungus)	MGG_17976	XP_003721002.1
Schizosaccharomyces pombe (fission yeast)	SPBC4B4.01c	NP_596418.1
Arabidopsis thaliana (thale cress)	PANK2	NP_194945.3

Gene Ontology
Bibliography

Related articles in PubMed

Human pantothenate kinase 4 is a pseudo-pantothenate kinase.
Yao J, Subramanian C, Rock CO, Jackowski S
Protein science : a publication of the Protein Society28(6)1031-1047(2019 06)

PanK4 inhibits pancreatic beta-cell apoptosis by decreasing the transcriptional level of pro-caspase-9.
Xiang RL, Yang YL, Zuo J, Xiao XH, Chang YS, De Fang F
Cell research17(11)966-8(2007 Nov)

High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2).
Li Y, Chang Y, Zhang L, Feng Q, Liu Z, Zhang Y, Zuo J, Meng Y, Fang F
Molecular and cellular biochemistry277(1-2)117-25(2005 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pank4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pank4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00843	NM_133531.2 Latest version!	Rattus norvegicus pantothenate kinase 4 (Pank4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pank4 ( NM_133531.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598215.1 Rattus norvegicus pantothenate kinase 4 (Pank4), mRNA.

Price & Availability↑

CloneID	ORa00843
Clone ID Related Accession (Same CDS sequence)	NM_133531.2
Accession Version	NM_133531.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573833600000
Organism	Rattus norvegicus(Norway rat)
Product	4'-phosphopantetheine phosphatase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF399873.1. On Feb 21, 2013 this sequence version replaced NM_133531.1. ##Evidence-Data-START## Transcript exon combination :: AF399873.1, FQ223969.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGT GCCGGGCGAG TGGCGGCGGG AGCGGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGAAAC CTGGAGAACG CCAAGCGCTT CGCCATTGAT 
ATAGGTGGAT CACTGACCAA GTTGGCATAC TATTCCACAG TACAGCACAA AGTGGCCAAA 
GTGAGGTCTT TTGACCACCC AGGAAAGGAC GCAGAACAGG ACCATGAGCC GCCCTATGAG 
ATCTCAGTTC AGGAGGAGAT CACAGCTCGT CTGCATTTCA TCAAGTTTGA GAACACCTAC 
ATGGAAGCCT GCCTGGACTT TATCAGAGAC CACCTTGTCA ACACTGAGAC CAAGGTCATC 
CAGGCCACAG GGGGTGGAGC CTACAAGTTC AAGGACCTCA TCGAGGAGAA GCTGCGTCTG 
AAGGTGGACA AAGAGGATGT GATGACCTGC TTGATTAAGG GGTGCAACTT CGTGCTGAAG 
AACATCCCAC ATGAGGCCTT CATGTACCAG AAAGACTCAG ACCCAGAGTT TCGGTTTCAG 
ACAAATCACC CGAACATCTT CCCCTACCTC CTAGTCAACA TTGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACAGAGGA CCGGTTCGAG TGGATTGGTG GGAGCTCCAT TGGAGGAGGC 
ACCTTCTGGG GGCTTGGGGC TCTGCTCACC AAAACAAAGA AGTTTGATGA GCTGCTGCAG 
CTGGCTTCCA GAGGCCGGCA CGCCAATGTT GACATGCTGG TACAAGACAT CTATGGAGGG 
GCCCACCAGA CCCTGGGGCT GAGCGGCAAT CTCATCGCAA GCAGTTTTGG GAAGTCAGCC 
ACTGCTGACA GAGAGTTCTC CAAAGAAGAC ATGGCCAAGA GCCTGCTGCA CATGATCAGC 
AATGACATTG GACAGCTCGC CTGTCTCTAC GCCAAGCTTC ATGGCCTAGA CAGGGTCTAC 
TTTGGGGGTT TCTTCATCCG GGGTCACCCT GTGACCATGC GCACCATCAC CTACAGCATT 
AACTTCTTCT CTAAGGGTGA AGTCCAGGCA CTCTTCCTGA GACATGAAGG CTACCTGGGA 
GCCATCGGGG CATTTTTGAA AGGAGCCGAG CAAGATAATC CTAACCAGTA CAGCTGGGGT 
GAGAACTACG CGGCCAGCTC CGGGCTGATG AGCACGGCGC CGGAGCTGTG CCCGACACAG 
CGGGCAAGGA GCGGCACATT TGACCTGCTG GAAATGGACC GCCTGGAGAG ACCCCTGGTC 
AACCTGCCCC TCCTCCTGGA CCCATCCTCC TATGTGCCCG ACACGGTAGA CCTCACTGAC 
GATGCTCTGG CCCGACAGTA CTGGCTCACA TGCTTTGAGG AGGCTCTGGA TGGGGTGGTG 
AAGCGAGCTG TGGCCAGCCA GCCAGAATCC GTGGATGCAG CTGAGAGGGC AGAGAAGTTC 
CGTCAGAAGT ACTGGGGCAA ACTTCAGACT CTGAGGCACC AGCCCTTTGC TTATGGGACG 
CTGACTGTGC GCAGCCTGTT GGACACAAGA GAGCACTGTT TGAATGAGTT CAACTTCCCA 
GACCCCTACT CCAAGGTGAA GCAGAAAGAA AACGGCCTCG CGCTAAAGTG CTTTCAGAGC 
GTGACTCGCT CGCTGGACTC ACTAGGCTGG GAGGAGCGGC AGCTGGCCCT GGTGAAGGGG 
CTGTTAGCTG GGAATGTCTT TGACTGGGGA GCCAAGGCTG TGTCTGACGT CCTGGAATCG 
GACCCCCAGT TTGGGTTTGA AGAAGCAAAG AGAAAATTGC AAGAACGGCC CTGGCTGGTG 
GATTCCTACA CCAAGTGGCT CCAGAGGTTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCTGTAGAG GGATAGAGGT CATCTTGGCA TGCAACTCAG GCCCTGCCCT GAACGATGTG 
ACCTACAGTG AGTCTCTCAT TGTGGCAGAA CGCATTGCAG CCATGGACCC CATCATCTGC 
ACTGCACTCA GAGAAGACAG GCTACTGCTG GTGCAGACCG GTTCCAGTCC CCCATGCCTA 
GATCTCAGCC GCCTAGATAA GGGACTGGCT GTGCTGGTGC GGGAGCGTGG TGCCGACCTG 
GTGGTCATCG AGGGAATGGG CCGTGCTGTC CACACCAACT ACCATGCTTT GCTGCGATGT 
GAGAGTCTCA AGCTGGCCGT GGTGAAGAAC GCCTGGCTGG CTGAGCGTCT GGGTGGCCAG 
CTCTTCAGTG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598215.1
CDS	5..2326
Translation	MAECRASGGGSGGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHPGKDAEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAASSGLMSTAPELCPTQRARSGTFDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESVDAAERAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLCRGIEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSPPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAVHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYEVPAE

Target ORF information:

RefSeq Version	NM_133531.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pantothenate kinase 4 (Pank4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133531.2

ORF Insert Sequence:

ATGGCGGAGT GCCGGGCGAG TGGCGGCGGG AGCGGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGAAAC CTGGAGAACG CCAAGCGCTT CGCCATTGAT 
ATAGGTGGAT CACTGACCAA GTTGGCATAC TATTCCACAG TACAGCACAA AGTGGCCAAA 
GTGAGGTCTT TTGACCACCC AGGAAAGGAC GCAGAACAGG ACCATGAGCC GCCCTATGAG 
ATCTCAGTTC AGGAGGAGAT CACAGCTCGT CTGCATTTCA TCAAGTTTGA GAACACCTAC 
ATGGAAGCCT GCCTGGACTT TATCAGAGAC CACCTTGTCA ACACTGAGAC CAAGGTCATC 
CAGGCCACAG GGGGTGGAGC CTACAAGTTC AAGGACCTCA TCGAGGAGAA GCTGCGTCTG 
AAGGTGGACA AAGAGGATGT GATGACCTGC TTGATTAAGG GGTGCAACTT CGTGCTGAAG 
AACATCCCAC ATGAGGCCTT CATGTACCAG AAAGACTCAG ACCCAGAGTT TCGGTTTCAG 
ACAAATCACC CGAACATCTT CCCCTACCTC CTAGTCAACA TTGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACAGAGGA CCGGTTCGAG TGGATTGGTG GGAGCTCCAT TGGAGGAGGC 
ACCTTCTGGG GGCTTGGGGC TCTGCTCACC AAAACAAAGA AGTTTGATGA GCTGCTGCAG 
CTGGCTTCCA GAGGCCGGCA CGCCAATGTT GACATGCTGG TACAAGACAT CTATGGAGGG 
GCCCACCAGA CCCTGGGGCT GAGCGGCAAT CTCATCGCAA GCAGTTTTGG GAAGTCAGCC 
ACTGCTGACA GAGAGTTCTC CAAAGAAGAC ATGGCCAAGA GCCTGCTGCA CATGATCAGC 
AATGACATTG GACAGCTCGC CTGTCTCTAC GCCAAGCTTC ATGGCCTAGA CAGGGTCTAC 
TTTGGGGGTT TCTTCATCCG GGGTCACCCT GTGACCATGC GCACCATCAC CTACAGCATT 
AACTTCTTCT CTAAGGGTGA AGTCCAGGCA CTCTTCCTGA GACATGAAGG CTACCTGGGA 
GCCATCGGGG CATTTTTGAA AGGAGCCGAG CAAGATAATC CTAACCAGTA CAGCTGGGGT 
GAGAACTACG CGGCCAGCTC CGGGCTGATG AGCACGGCGC CGGAGCTGTG CCCGACACAG 
CGGGCAAGGA GCGGCACATT TGACCTGCTG GAAATGGACC GCCTGGAGAG ACCCCTGGTC 
AACCTGCCCC TCCTCCTGGA CCCATCCTCC TATGTGCCCG ACACGGTAGA CCTCACTGAC 
GATGCTCTGG CCCGACAGTA CTGGCTCACA TGCTTTGAGG AGGCTCTGGA TGGGGTGGTG 
AAGCGAGCTG TGGCCAGCCA GCCAGAATCC GTGGATGCAG CTGAGAGGGC AGAGAAGTTC 
CGTCAGAAGT ACTGGGGCAA ACTTCAGACT CTGAGGCACC AGCCCTTTGC TTATGGGACG 
CTGACTGTGC GCAGCCTGTT GGACACAAGA GAGCACTGTT TGAATGAGTT CAACTTCCCA 
GACCCCTACT CCAAGGTGAA GCAGAAAGAA AACGGCCTCG CGCTAAAGTG CTTTCAGAGC 
GTGACTCGCT CGCTGGACTC ACTAGGCTGG GAGGAGCGGC AGCTGGCCCT GGTGAAGGGG 
CTGTTAGCTG GGAATGTCTT TGACTGGGGA GCCAAGGCTG TGTCTGACGT CCTGGAATCG 
GACCCCCAGT TTGGGTTTGA AGAAGCAAAG AGAAAATTGC AAGAACGGCC CTGGCTGGTG 
GATTCCTACA CCAAGTGGCT CCAGAGGTTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCTGTAGAG GGATAGAGGT CATCTTGGCA TGCAACTCAG GCCCTGCCCT GAACGATGTG 
ACCTACAGTG AGTCTCTCAT TGTGGCAGAA CGCATTGCAG CCATGGACCC CATCATCTGC 
ACTGCACTCA GAGAAGACAG GCTACTGCTG GTGCAGACCG GTTCCAGTCC CCCATGCCTA 
GATCTCAGCC GCCTAGATAA GGGACTGGCT GTGCTGGTGC GGGAGCGTGG TGCCGACCTG 
GTGGTCATCG AGGGAATGGG CCGTGCTGTC CACACCAACT ACCATGCTTT GCTGCGATGT 
GAGAGTCTCA AGCTGGCCGT GGTGAAGAAC GCCTGGCTGG CTGAGCGTCT GGGTGGCCAG 
CTCTTCAGTG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human pantothenate kinase 4 is a pseudo-pantothenate kinase.
Protein science : a publication of the Protein Society28(6)1031-1047(2019 06)
Yao J,Subramanian C,Rock CO,Jackowski S

PanK4 inhibits pancreatic beta-cell apoptosis by decreasing the transcriptional level of pro-caspase-9.
Cell research17(11)966-8(2007 Nov)
Xiang RL,Yang YL,Zuo J,Xiao XH,Chang YS,De Fang F

High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2).
Molecular and cellular biochemistry277(1-2)117-25(2005 Sep)
Li Y,Chang Y,Zhang L,Feng Q,Liu Z,Zhang Y,Zuo J,Meng Y,Fang F

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Pank4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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