Cysltr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cysltr2
Entrez Gene ID	170926
Full Name	cysteinyl leukotriene receptor 2
Synonyms	Cyslt2,RSBPT32
General protein information	Preferred Names cysteinyl leukotriene receptor 2 Names cysteinyl leukotriene receptor 2 cysteinyl leukotriene CysLT2 receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p11
Summary	putative cysteinyl leukotriene receptor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133413.1	NP_596904.1	cysteinyl leukotriene receptor 2
XM_008770843.2	XP_008769065.1	cysteinyl leukotriene receptor 2 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cysltr2	NP_001155884.1
Danio rerio (zebrafish)	LOC100002717	XP_001342441.3
Canis lupus familiaris (dog)	CYSLTR2	XP_005633933.1
Bos taurus (cattle)	CYSLTR2	NP_001095710.1
Rattus norvegicus (Norway rat)	Cysltr2	NP_596904.1
Gallus gallus (chicken)	CYSLTR2	XP_004938765.1
Homo sapiens (human)	CYSLTR2	NP_065110.1
Pan troglodytes (chimpanzee)	CYSLTR2	XP_003954484.1
Macaca mulatta (Rhesus monkey)	CYSLTR2	XP_001101676.2
Danio rerio (zebrafish)	LOC100334963	XP_002662591.2

Gene Ontology
Bibliography

Related articles in PubMed

Cysteinyl leukotriene receptor 2 is spatiotemporally involved in neuron injury, astrocytosis and microgliosis after focal cerebral ischemia in rats.
Zhao CZ, Zhao B, Zhang XY, Huang XQ, Shi WZ, Liu HL, Fang SH, Lu YB, Zhang WP, Tang FD, Wei EQ
Neuroscience1891-11(2011 Aug)

CysLT2 receptor-mediated AQP4 up-regulation is involved in ischemic-like injury through activation of ERK and p38 MAPK in rat astrocytes.
Qi LL, Fang SH, Shi WZ, Huang XQ, Zhang XY, Lu YB, Zhang WP, Wei EQ
Life sciences88(1-2)50-6(2011 Jan)

Involvement of cysteinyl leukotriene receptors in angiogenesis in rat thoracic aortic rings.
Xu L, Zhang L, Liu L, Fang S, Lu Y, Wei E, Zhang W
Die Pharmazie65(10)750-4(2010 Oct)

Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice.
Shimbori C, Shiota N, Okunishi H
Experimental lung research36(5)292-301(2010 Jun)

Cysteinyl leukotriene receptors are expressed by tonsillar T cells of children with obstructive sleep apnea.
Kaditis AG, Ioannou MG, Chaidas K, Alexopoulos EI, Apostolidou M, Apostolidis T, Koukoulis G, Gourgoulianis K
Chest134(2)324-331(2008 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cysltr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cysltr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42478	NM_133413.1 Latest version!	Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa42478	XM_008770843.2 Latest version!	Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cysltr2 ( NM_133413.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_596904.1 Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa42478
Clone ID Related Accession (Same CDS sequence)	NM_133413.1 , XM_008770843.2
Accession Version	NM_133413.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	cysteinyl leukotriene receptor 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB052661.1. On Jun 26, 2012 this sequence version replaced XM_003752828.1. Transcript Variant: This variant (1) encodes the functional protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB052661.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGAGTAA CTGGGACCCC CAGCTATTAT AGTGACAAGA ACTGTACAAT AGAAAACTTC 
AAGAGGGACT TTTACCCTAT CATCTACCTG ATAATATTTG TCTGGGGAGC CTTGGGAAAT 
GGCTTTTCCA TATATGTCTT CCTACAGACT TACAAGAAGT CCACATCTGT GAATGTTTTC 
ATGCTCAACC TGGCCATTTC AGATTTCCTA TTCATAAGCA CCCTGCCCTT CAGGGCTGAC 
TATAATTTCA GAGGTTCTGA TTGGATATTT GGGGACTGGG CCTGCAGAAT TATGTCTTAT 
TCTTTATATG TCAACATGTA TACTAGCATT TATTTCCTAA CTGTGCTGAG TATTGTGCGC 
TTCCTGGCCA CTGCCCACCC CTTCCAGATG CTCCATATCA CCAGCGTTAG GAGTGCCTGG 
ATCCTCTGTG GGATTATATG GGTCTTCATC ATGGCTTCCT CAGGACTGCT TCTGAAGCAT 
GGCCAAGAGA AGAAAAATAA CACTACATTG TGCTTTGAGC TGAATCTCCA AAAGTTTAAA 
AATCTCGTCA TCTTGAACTA CATTGCATTA GGGGTGGGCT TCTTGCTTCC ATTTTTCATA 
CTCACCATCT GCTACCTGTT GATCATCCGG GTCTTGTTAA AGGTGGAGAT TCCAGAATCA 
GGTCCACGGG ATGCTCAGAG GAAGGCACTG ACCACTATCG TCATTGCCAT GATCATCTTC 
CTCCTCTGTT TTCTGCCATA CCATGCACTT CGGACCATCC ACTTGGTCAC ATGGGATGCA 
GATTCATGTA TGGATGAATT ACATAAGGCC ACGGTCATCA CTCTGACCTT GGCTGCAGCC 
AACAGCTGCT TCAATCCCTT TCTCTATTAT TTTGCTGGAG AGAATTTCAA AGCACGATTA 
AGGGCTATAT TCAGCAAAGA TCATCTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_596904.1
CDS	1..930
Translation	MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL

Target ORF information:

RefSeq Version	NM_133413.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133413.1

ORF Insert Sequence:

ATGGGAGTAA CTGGGACCCC CAGCTATTAT AGTGACAAGA ACTGTACAAT AGAAAACTTC 
AAGAGGGACT TTTACCCTAT CATCTACCTG ATAATATTTG TCTGGGGAGC CTTGGGAAAT 
GGCTTTTCCA TATATGTCTT CCTACAGACT TACAAGAAGT CCACATCTGT GAATGTTTTC 
ATGCTCAACC TGGCCATTTC AGATTTCCTA TTCATAAGCA CCCTGCCCTT CAGGGCTGAC 
TATAATTTCA GAGGTTCTGA TTGGATATTT GGGGACTGGG CCTGCAGAAT TATGTCTTAT 
TCTTTATATG TCAACATGTA TACTAGCATT TATTTCCTAA CTGTGCTGAG TATTGTGCGC 
TTCCTGGCCA CTGCCCACCC CTTCCAGATG CTCCATATCA CCAGCGTTAG GAGTGCCTGG 
ATCCTCTGTG GGATTATATG GGTCTTCATC ATGGCTTCCT CAGGACTGCT TCTGAAGCAT 
GGCCAAGAGA AGAAAAATAA CACTACATTG TGCTTTGAGC TGAATCTCCA AAAGTTTAAA 
AATCTCGTCA TCTTGAACTA CATTGCATTA GGGGTGGGCT TCTTGCTTCC ATTTTTCATA 
CTCACCATCT GCTACCTGTT GATCATCCGG GTCTTGTTAA AGGTGGAGAT TCCAGAATCA 
GGTCCACGGG ATGCTCAGAG GAAGGCACTG ACCACTATCG TCATTGCCAT GATCATCTTC 
CTCCTCTGTT TTCTGCCATA CCATGCACTT CGGACCATCC ACTTGGTCAC ATGGGATGCA 
GATTCATGTA TGGATGAATT ACATAAGGCC ACGGTCATCA CTCTGACCTT GGCTGCAGCC 
AACAGCTGCT TCAATCCCTT TCTCTATTAT TTTGCTGGAG AGAATTTCAA AGCACGATTA 
AGGGCTATAT TCAGCAAAGA TCATCTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cysltr2 ( XM_008770843.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008769065.1 Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42478
Clone ID Related Accession (Same CDS sequence)	NM_133413.1 , XM_008770843.2
Accession Version	XM_008770843.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	cysteinyl leukotriene receptor 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008770843.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTAA CTGGGACCCC CAGCTATTAT AGTGACAAGA ACTGTACAAT AGAAAACTTC 
AAGAGGGACT TTTACCCTAT CATCTACCTG ATAATATTTG TCTGGGGAGC CTTGGGAAAT 
GGCTTTTCCA TATATGTCTT CCTACAGACT TACAAGAAGT CCACATCTGT GAATGTTTTC 
ATGCTCAACC TGGCCATTTC AGATTTCCTA TTCATAAGCA CCCTGCCCTT CAGGGCTGAC 
TATAATTTCA GAGGTTCTGA TTGGATATTT GGGGACTGGG CCTGCAGAAT TATGTCTTAT 
TCTTTATATG TCAACATGTA TACTAGCATT TATTTCCTAA CTGTGCTGAG TATTGTGCGC 
TTCCTGGCCA CTGCCCACCC CTTCCAGATG CTCCATATCA CCAGCGTTAG GAGTGCCTGG 
ATCCTCTGTG GGATTATATG GGTCTTCATC ATGGCTTCCT CAGGACTGCT TCTGAAGCAT 
GGCCAAGAGA AGAAAAATAA CACTACATTG TGCTTTGAGC TGAATCTCCA AAAGTTTAAA 
AATCTCGTCA TCTTGAACTA CATTGCATTA GGGGTGGGCT TCTTGCTTCC ATTTTTCATA 
CTCACCATCT GCTACCTGTT GATCATCCGG GTCTTGTTAA AGGTGGAGAT TCCAGAATCA 
GGTCCACGGG ATGCTCAGAG GAAGGCACTG ACCACTATCG TCATTGCCAT GATCATCTTC 
CTCCTCTGTT TTCTGCCATA CCATGCACTT CGGACCATCC ACTTGGTCAC ATGGGATGCA 
GATTCATGTA TGGATGAATT ACATAAGGCC ACGGTCATCA CTCTGACCTT GGCTGCAGCC 
AACAGCTGCT TCAATCCCTT TCTCTATTAT TTTGCTGGAG AGAATTTCAA AGCACGATTA 
AGGGCTATAT TCAGCAAAGA TCATCTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008769065.1
CDS	2160..3089
Translation	MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL

Target ORF information:

RefSeq Version	XM_008770843.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cysteinyl leukotriene receptor 2 (Cysltr2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770843.2

ORF Insert Sequence:

ATGGGAGTAA CTGGGACCCC CAGCTATTAT AGTGACAAGA ACTGTACAAT AGAAAACTTC 
AAGAGGGACT TTTACCCTAT CATCTACCTG ATAATATTTG TCTGGGGAGC CTTGGGAAAT 
GGCTTTTCCA TATATGTCTT CCTACAGACT TACAAGAAGT CCACATCTGT GAATGTTTTC 
ATGCTCAACC TGGCCATTTC AGATTTCCTA TTCATAAGCA CCCTGCCCTT CAGGGCTGAC 
TATAATTTCA GAGGTTCTGA TTGGATATTT GGGGACTGGG CCTGCAGAAT TATGTCTTAT 
TCTTTATATG TCAACATGTA TACTAGCATT TATTTCCTAA CTGTGCTGAG TATTGTGCGC 
TTCCTGGCCA CTGCCCACCC CTTCCAGATG CTCCATATCA CCAGCGTTAG GAGTGCCTGG 
ATCCTCTGTG GGATTATATG GGTCTTCATC ATGGCTTCCT CAGGACTGCT TCTGAAGCAT 
GGCCAAGAGA AGAAAAATAA CACTACATTG TGCTTTGAGC TGAATCTCCA AAAGTTTAAA 
AATCTCGTCA TCTTGAACTA CATTGCATTA GGGGTGGGCT TCTTGCTTCC ATTTTTCATA 
CTCACCATCT GCTACCTGTT GATCATCCGG GTCTTGTTAA AGGTGGAGAT TCCAGAATCA 
GGTCCACGGG ATGCTCAGAG GAAGGCACTG ACCACTATCG TCATTGCCAT GATCATCTTC 
CTCCTCTGTT TTCTGCCATA CCATGCACTT CGGACCATCC ACTTGGTCAC ATGGGATGCA 
GATTCATGTA TGGATGAATT ACATAAGGCC ACGGTCATCA CTCTGACCTT GGCTGCAGCC 
AACAGCTGCT TCAATCCCTT TCTCTATTAT TTTGCTGGAG AGAATTTCAA AGCACGATTA 
AGGGCTATAT TCAGCAAAGA TCATCTATAG