Slc5a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc5a6
Entrez Gene ID	170551
Full Name	solute carrier family 5 member 6
Synonyms	SMVT
General protein information	Preferred Names solute carrier family 5 member 6 Names sodium-dependent multivitamin transporter Na(+)-dependent multivitamin transporter solute carrier family 5 (sodium-dependent vitamin transporter), member 6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q14
Summary	mediates sodium-dependent transport of pantothenate, biotin, and lipoate; plays a role in intestinal uptake of biotin and in transplacental vitamin transport [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_130746.1	NP_570102.1	sodium-dependent multivitamin transporter

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC5A6	XP_515353.3
Macaca mulatta (Rhesus monkey)	SLC5A6	XP_001090644.1
Canis lupus familiaris (dog)	SLC5A6	XP_005630310.1
Rattus norvegicus (Norway rat)	Slc5a6	NP_570102.1
Xenopus tropicalis (tropical clawed frog)	slc5a6	NP_001005686.1
Danio rerio (zebrafish)	slc5a6	NP_001020699.1
Homo sapiens (human)	SLC5A6	NP_066918.2
Bos taurus (cattle)	SLC5A6	NP_001039684.2
Mus musculus (house mouse)	Slc5a6	NP_001171092.1
Danio rerio (zebrafish)	si:dkey-5g7.3	NP_001020700.2

Gene Ontology
Bibliography

Related articles in PubMed

Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat.
Nabokina SM, Subramanian VS, Said HM
American journal of physiology. Renal physiology284(4)F737-42(2003 Apr)

Molecular characterization of the 5' regulatory region of rat sodium-dependent multivitamin transporter gene.
Chatterjee NS, Rubin SA, Said HM
American journal of physiology. Cell physiology280(3)C548-55(2001 Mar)

Molecular mechanism of the intestinal biotin transport process.
Chatterjee NS, Kumar CK, Ortiz A, Rubin SA, Said HM
The American journal of physiology277(4)C605-13(1999 10)

Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.
Prasad PD, Wang H, Kekuda R, Fujita T, Fei YJ, Devoe LD, Leibach FH, Ganapathy V
The Journal of biological chemistry273(13)7501-6(1998 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Slc5a6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc5a6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00446	NM_130746.1 Latest version!	Rattus norvegicus solute carrier family 5 member 6 (Slc5a6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc5a6 ( NM_130746.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_570102.1 Rattus norvegicus solute carrier family 5 member 6 (Slc5a6), mRNA.

Price & Availability↑

CloneID	ORa00446
Clone ID Related Accession (Same CDS sequence)	NM_130746.1
Accession Version	NM_130746.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1905bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Rattus norvegicus(Norway rat)
Product	sodium-dependent multivitamin transporter
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF026554.1. ##Evidence-Data-START## Transcript exon combination :: AF026554.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGACTGTGG CGAGCACTGC GGCTCCCTCC TATACAACCT CAGACACCAA CCGGGTTATT 
TCCACCTTTT CTGTTGTGGA CTATGTGGTG TTTGGCCTGT TGCTGGTTCT CTCCCTTGTC 
ATTGGGCTCT ATCATGCTTG CCGAGGCTGG GGCCGCCATA CTGTTGGTGA GCTGCTGATG 
GCAGACCGAA AAATGGGCTG CCTTCCTGTG GCACTGTCCT TGCTGGCCAC CTTCCAGTCA 
GCCGTGGCGA TCCTTGGGGG ACCAGCTGAG ATCTACCGAT TTGGAACCCA GTATTGGTTC 
CTGGGGTGCT CCTACTTCCT GGGGCTTCTG ATCCCTGCTC ACATCTTCAT CCCTGTCTTC 
TACCGCCTGC ATCTTACCAG CGCCTATGAG TACCTAGAGC TCCGCTTCAA TAAAGCAGTC 
CGGATCTGTG GGACTGTGAC CTTCATCTTT CAGATGGTGG TCTACATGGG AGTGGCTCTC 
TATGCACCGT CCCTGGCCCT CAATGCAGTG ACTGGATTTG ATCTATGGCT GTCAGTCCTG 
GCCCTAGGAA TTGTCTGCAA CATCTACACT GCACTGGGTG GGCTGAAGGC TGTCATCTGG 
ACAGATGTGT TCCAAACGTT GATCATGTTC CTAGGGCAGC TGGTGGTTAT CATTGTAGGA 
GCGGCCAAAG TGGGCGGCTT GGGGCATGTA TGGGCTGTGG CTTCCCAGCA TGGCCTCATC 
TCTGGGATTG AGCTGGATCC TGACCCCTTT GTACGTCATA CTTTCTGGAC TTTGGCCTTT 
GGCGGCGTCT TCATGATGCT CTCCTTATAT GGAGTGAATC AGGCTCAGGT GCAGCGCTAC 
CTCAGTTCCC ACTCAGAGAA GGCTGCTGTG CTCTCCTGCT ATGCAGTGTT CCCTTGCCAG 
CAAGTGGCCC TCTGCATGAG CTGCCTCATT GGTCTGGTCA TGTTTGCCTA TTATAAGAAA 
TATAGTATGA GCCCCCAACA AGAGCAAGCA GCCCCTGACC AGTTAGTCCT CTATTTTGTG 
ATGGACCTCC TGAAAGACAT GCCAGGGCTG CCCGGGCTCT TCGTTGCTTG CCTCTTCAGT 
GGATCTCTCA GCACCATATC CTCCGCATTC AATTCACTGG CCACTGTCAC AATGGAAGAC 
CTGATCCAGC CCTGGTTCCC TCAGTTGACT GAAACCCGGG CCATCATGCT CTCTCGAAGC 
CTTGCCTTTG CCTATGGGCT AGTTTGCCTG GGAATGGCCT ATGTTTCCTC TCATCTGGGA 
TCAGTGCTCC AGGCAGCACT CAGCATCTTT GGCATGGTTG GAGGGCCACT GCTGGGACTC 
TTCTGCCTTG GGATGTTCTT TCCGTGTGCC AACCCTCTTG GTGCCATTGT AGGCCTGTTG 
ACGGGACTCA CCATGGCCTT CTGGATTGGC ATTGGGAGCA TAGTAAGCAG GATGAGTTCT 
GCTGCAGCAT CCCCTCCCCT TAATGGATCC AGCTCCTTCC TGCCCAGCAA TCTAACTGTC 
GCCACTGTGA CCACCCTGAT GCCTTCTACC CTGTCCAAGC CCACAGGACT GCAGCAGTTC 
TATTCCCTGT CCTATTTATG GTACAGTGCG CACAACTCCA CCACAGTCAT TGCAGTGGGC 
CTGATTGTCA GTCTGCTCAC TGGGGGAATG CGGGGCCGGT CCCTGAACCC TGGCACCATT 
TACCCTGTGT TGCCAAAGCT CCTTGCACTC CTGCCCTTAT CCTGCCAGAA GCGGCTTTGC 
TGGAGAAGCC ACAACCAGGA TATCCCTGTG GTCACCAACC TGTTTCCAGA GAAGATGGGG 
AACGGAGCGC TGCAGGACAG CAGAGACAAA GAGAGGATGG CTGAAGATGG CCTTGTCCAT 
CAGCCATGCA GCCCCACCTA CATTGTCCAA GAGACGTCCC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570102.1
CDS	413..2317
Translation	MTVASTAAPSYTTSDTNRVISTFSVVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSHSEKAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQPWFPQLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAAASPPLNGSSSFLPSNLTVATVTTLMPSTLSKPTGLQQFYSLSYLWYSAHNSTTVIAVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALLPLSCQKRLCWRSHNQDIPVVTNLFPEKMGNGALQDSRDKERMAEDGLVHQPCSPTYIVQETSL

Target ORF information:

RefSeq Version	NM_130746.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 5 member 6 (Slc5a6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130746.1

ORF Insert Sequence:

ATGACTGTGG CGAGCACTGC GGCTCCCTCC TATACAACCT CAGACACCAA CCGGGTTATT 
TCCACCTTTT CTGTTGTGGA CTATGTGGTG TTTGGCCTGT TGCTGGTTCT CTCCCTTGTC 
ATTGGGCTCT ATCATGCTTG CCGAGGCTGG GGCCGCCATA CTGTTGGTGA GCTGCTGATG 
GCAGACCGAA AAATGGGCTG CCTTCCTGTG GCACTGTCCT TGCTGGCCAC CTTCCAGTCA 
GCCGTGGCGA TCCTTGGGGG ACCAGCTGAG ATCTACCGAT TTGGAACCCA GTATTGGTTC 
CTGGGGTGCT CCTACTTCCT GGGGCTTCTG ATCCCTGCTC ACATCTTCAT CCCTGTCTTC 
TACCGCCTGC ATCTTACCAG CGCCTATGAG TACCTAGAGC TCCGCTTCAA TAAAGCAGTC 
CGGATCTGTG GGACTGTGAC CTTCATCTTT CAGATGGTGG TCTACATGGG AGTGGCTCTC 
TATGCACCGT CCCTGGCCCT CAATGCAGTG ACTGGATTTG ATCTATGGCT GTCAGTCCTG 
GCCCTAGGAA TTGTCTGCAA CATCTACACT GCACTGGGTG GGCTGAAGGC TGTCATCTGG 
ACAGATGTGT TCCAAACGTT GATCATGTTC CTAGGGCAGC TGGTGGTTAT CATTGTAGGA 
GCGGCCAAAG TGGGCGGCTT GGGGCATGTA TGGGCTGTGG CTTCCCAGCA TGGCCTCATC 
TCTGGGATTG AGCTGGATCC TGACCCCTTT GTACGTCATA CTTTCTGGAC TTTGGCCTTT 
GGCGGCGTCT TCATGATGCT CTCCTTATAT GGAGTGAATC AGGCTCAGGT GCAGCGCTAC 
CTCAGTTCCC ACTCAGAGAA GGCTGCTGTG CTCTCCTGCT ATGCAGTGTT CCCTTGCCAG 
CAAGTGGCCC TCTGCATGAG CTGCCTCATT GGTCTGGTCA TGTTTGCCTA TTATAAGAAA 
TATAGTATGA GCCCCCAACA AGAGCAAGCA GCCCCTGACC AGTTAGTCCT CTATTTTGTG 
ATGGACCTCC TGAAAGACAT GCCAGGGCTG CCCGGGCTCT TCGTTGCTTG CCTCTTCAGT 
GGATCTCTCA GCACCATATC CTCCGCATTC AATTCACTGG CCACTGTCAC AATGGAAGAC 
CTGATCCAGC CCTGGTTCCC TCAGTTGACT GAAACCCGGG CCATCATGCT CTCTCGAAGC 
CTTGCCTTTG CCTATGGGCT AGTTTGCCTG GGAATGGCCT ATGTTTCCTC TCATCTGGGA 
TCAGTGCTCC AGGCAGCACT CAGCATCTTT GGCATGGTTG GAGGGCCACT GCTGGGACTC 
TTCTGCCTTG GGATGTTCTT TCCGTGTGCC AACCCTCTTG GTGCCATTGT AGGCCTGTTG 
ACGGGACTCA CCATGGCCTT CTGGATTGGC ATTGGGAGCA TAGTAAGCAG GATGAGTTCT 
GCTGCAGCAT CCCCTCCCCT TAATGGATCC AGCTCCTTCC TGCCCAGCAA TCTAACTGTC 
GCCACTGTGA CCACCCTGAT GCCTTCTACC CTGTCCAAGC CCACAGGACT GCAGCAGTTC 
TATTCCCTGT CCTATTTATG GTACAGTGCG CACAACTCCA CCACAGTCAT TGCAGTGGGC 
CTGATTGTCA GTCTGCTCAC TGGGGGAATG CGGGGCCGGT CCCTGAACCC TGGCACCATT 
TACCCTGTGT TGCCAAAGCT CCTTGCACTC CTGCCCTTAT CCTGCCAGAA GCGGCTTTGC 
TGGAGAAGCC ACAACCAGGA TATCCCTGTG GTCACCAACC TGTTTCCAGA GAAGATGGGG 
AACGGAGCGC TGCAGGACAG CAGAGACAAA GAGAGGATGG CTGAAGATGG CCTTGTCCAT 
CAGCCATGCA GCCCCACCTA CATTGTCCAA GAGACGTCCC TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat.
American journal of physiology. Renal physiology284(4)F737-42(2003 Apr)
Nabokina SM,Subramanian VS,Said HM

Molecular characterization of the 5' regulatory region of rat sodium-dependent multivitamin transporter gene.
American journal of physiology. Cell physiology280(3)C548-55(2001 Mar)
Chatterjee NS,Rubin SA,Said HM

Molecular mechanism of the intestinal biotin transport process.
The American journal of physiology277(4)C605-13(1999 10)
Chatterjee NS,Kumar CK,Ortiz A,Rubin SA,Said HM

Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.
The Journal of biological chemistry273(13)7501-6(1998 Mar)
Prasad PD,Wang H,Kekuda R,Fujita T,Fei YJ,Devoe LD,Leibach FH,Ganapathy V

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Slc5a6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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