Cfh cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cfh
Entrez Gene ID	155012
Full Name	complement factor H
Synonyms	AMBP-1,AMBP1,Fh
General protein information	Preferred Names complement factor H Names complement factor H adrenomedullin binding protein-1 complement component factor H complement inhibitory factor H platelet complement factor H
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q13
Summary	regulator of complement cascade activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_130409.2	NP_569093.2	complement factor H precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cfh	NP_034018.2
Rattus norvegicus (Norway rat)	Cfh	NP_569093.2
Xenopus tropicalis (tropical clawed frog)	LOC100497803	XP_002938381.1
Xenopus tropicalis (tropical clawed frog)	LOC100496324	XP_002938373.2
Danio rerio (zebrafish)	LOC100535929	XP_003201110.1
Macaca mulatta (Rhesus monkey)	LOC717346	XP_001111875.1
Danio rerio (zebrafish)	cfh	NP_001186119.1
Danio rerio (zebrafish)	cfhl1	NP_001032792.1
Xenopus tropicalis (tropical clawed frog)	cfh	NP_989218.1
Xenopus tropicalis (tropical clawed frog)	LOC100487763	XP_002932192.2
Xenopus tropicalis (tropical clawed frog)	LOC100492100	XP_002932215.2
Xenopus tropicalis (tropical clawed frog)	LOC100497957	XP_002938382.2
Danio rerio (zebrafish)	LOC100536017	XP_003201111.1
Danio rerio (zebrafish)	LOC100536554	XP_003201112.1
Homo sapiens (human)	CFH	NP_000177.2
Canis lupus familiaris (dog)	LOC478952	XP_536110.2
Gallus gallus (chicken)	CFH	XP_426613.3
Xenopus tropicalis (tropical clawed frog)	f13b	XP_004919518.1
Pan troglodytes (chimpanzee)	CFH	XP_001136531.1
Bos taurus (cattle)	CFH	NP_001029108.1
Xenopus tropicalis (tropical clawed frog)	LOC100491927	XP_002932214.2
Caenorhabditis elegans (roundworm)	F36H2.5	NP_001021461.2
Danio rerio (zebrafish)	cfhl2	NP_001007419.1
Caenorhabditis elegans (roundworm)	F36H2.3	NP_001251038.1
Xenopus tropicalis (tropical clawed frog)	LOC101731666	XP_004921059.1
Xenopus tropicalis (tropical clawed frog)	LOC100497496	XP_004919520.1
Danio rerio (zebrafish)	cfhl3	NP_001186120.1

Gene Ontology
Bibliography

Related articles in PubMed

The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Li TR, Jia YJ, Ma C, Qiu WY, Wang Q, Shao XQ, Lv RJ
Disease models & mechanisms11(3)(2018 03)

Modulation of miR-146a/complement factor H-mediated inflammatory responses in a rat model of temporal lobe epilepsy.
He F, Liu B, Meng Q, Sun Y, Wang W, Wang C
Bioscience reports36(6)(2016 12)

Circulating AIM prevents hepatocellular carcinoma through complement activation.
Maehara N, Arai S, Mori M, Iwamura Y, Kurokawa J, Kai T, Kusunoki S, Taniguchi K, Ikeda K, Ohara O, Yamamura KI, Miyazaki T
Cell reports9(1)61-74(2014 Oct)

Fusion protein comprising factor H domains 6 and 7 and human IgG1 Fc as an antibacterial immunotherapeutic.
Shaughnessy J, Vu DM, Punjabi R, Serra-Pladevall J, DeOliveira RB, Granoff DM, Ram S
Clinical and vaccine immunology : CVI21(10)1452-9(2014 Oct)

Identification of a Haemophilus influenzae factor H-Binding lipoprotein involved in serum resistance.
Fleury C, Su YC, Hallström T, Sandblad L, Zipfel PF, Riesbeck K
Journal of immunology (Baltimore, Md. : 1950)192(12)5913-23(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cfh gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cfh cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00362	NM_130409.2 Latest version!	Rattus norvegicus complement factor H (Cfh), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cfh ( NM_130409.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_569093.2 Rattus norvegicus complement factor H (Cfh), mRNA.

Price & Availability↑

CloneID	ORa00362
Clone ID Related Accession (Same CDS sequence)	NM_130409.2
Accession Version	NM_130409.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Rattus norvegicus(Norway rat)
Product	complement factor H precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CB816813.1, AJ320522.1, BC083174.1, CK359694.1 and CF110979.1. On Oct 19, 2005 this sequence version replaced NM_130409.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ320522.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGAGACTGT CAGCAAGAAT TATTTGGCTT ATATTATGGA CTGTTTGTGT AGCAGAAGAT 
TGTAAAGGTC CTCCTCCAAG AGAAAATTCA GAAATTCTCT CAGGTTCGTG GTCTGAACAA 
CTATATTCAG AAGGCACTCA GGCAACCTAC AAATGCCGCC CTGGATACCG AACACTTGGT 
ACTATTGTAA AAGTATGCAA GAATGGAGAA TGGGTACCTT CTAACCCATC AAGGATATGT 
CGGAAAAGGC CATGTGGGCA TCCCGGAGAC ACACCCTTTG GGTCCTTTAG GCTGGCAGTT 
GGATCTGAAT TTGAATTTGG TGCAAAGGTT GTTTATACAT GTGATGAAGG GTACCAACTC 
TTAGGTGAAA TTGATTACCG TGAATGTGAT GCAGATGGGT GGACCAATGA TATTCCAATA 
TGTGAAGTTG TGAAGTGCTT GCCAGTGACA GAACTGGAGA ATGGAAGAAT TGTGAGTGGT 
GCAGCCGAAC CAGACCAGGA ATATTATTTT GGACAGGTGG TACGCTTTGA ATGCAACTCC 
GGCTTCAAGA TTGAAGGACA GAAAGAAATG CACTGCTCAG AAAATGGCCT CTGGAGCAAT 
GAAAAGCCAC AGTGTGTGGA AATTTCTTGC CTGCCACCAC GAGTTGAAAA TGGAGATGGT 
ATATATCTGA AACCAGTTTA CAAGGAGAAT GAAAGATTCC AATATAAATG TAAGCAAGGT 
TTTGTGTACA AAGAAAGAGG GGATGCTGTC TGCACGGGTT CTGGATGGAA TCCTCAGCCT 
TCCTGTGAAG AAATGACATG TTTGACTCCA TATATTCCAA ATGGTATCTA CACACCTCAC 
AGGATTAAAC ACAGAATTGA TGATGAAATC AGATATGAAT GTAAAAATGG CTTCTATCCT 
GCAACCCGAT CACCTGTTTC AAAGTGTACA ATTACTGGCT GGATCCCTGC TCCAAGATGT 
AGCTTGAAAC CTTGTGATTT TCCACAATTC AAACATGGAC GTCTGTATTA TGAAGAAAGC 
CGGAGACCCT ACTTCCCAGT ACCTATAGGA AAGGAGTACA GCTATTACTG TGACAACGGG 
TTTACAACGC CTTCACAGTC ATACTGGGAC TACCTTCGTT GCACAGTAAA TGGGTGGGAG 
CCTGAAGTTC CATGCCTCAG GCAATGTATT TTCCATTATG TGGAATATGG AGAATCTTTA 
TACTGGCAAA GAAGATATAT AGAGGGTCAG TCTGCAAAAG TCCAGTGTCA CAGTGGCTAT 
AGTCTTCCAA ATGGTCAAGA TACAATATTA TGTACAGAAA ATGGCTGGTC CCCTCCTCCC 
AAATGCGTCC GTATCAAGAC TTGTTCAGTA TCAGATATAG AAATTGAAAA TGGGTTTTTT 
TCTGAATCTG ATTATACATA TGCTCTAAAT AGAAAAACAC GGTATAGATG TAAACAGGGA 
TATGTAACAA ATACCGGAGA AATATCAGGA ATAATTACTT GTCTTCAAGA TGGATGGTCA 
CCTCGACCCT CATGCATTAA GTCTTGTGAT ATGCCTGTAT TTGAGAATGC TATGACTAAG 
AATAATAACA CATGGTTTAA ACTCAATGAC AAATTAGACT ATGAATGTCA CATTGGATAT 
GAAAATGAAT ATAAACATAC CAAAGGCTCT ATAACATGTA CTTATGATGG ATGGTCTAGT 
ACACCCTCCT GTTATGAAAG AGAATGCAGC ATTCCCCTGT TACACCAAGA CTTAGTTGTT 
TTTCCCAGAG AAGTAAAATA CAAAGTTGGA GATTCGTTGA GTTTCTCTTG CCGTTCAGGA 
CACAGAGTTG GAGCAGATTT AGTGCAATGC TACCACTTTG GATGGTCCCC TAATTTCCCA 
ACGTGTGAAG GCCAAGTAAA ATCATGTGAC CAACCTCTTG AAATCCCGAA TGGGGAAATA 
AAGGGAACAA AAAAAGTTGA ATACAGCCAT GGTGACGTGG TGGAATATGA TTGCAAACCT 
AGATTTCTAC TGAAGGGACC CAATAAAATC CAGTGTGTTG ACGGGAAGTG GACAACCTTG 
CCGATATGCG TTGAGTATGA GAGAACATGT GGAGACCTTC CTGCACTTGA GCATGGCTCT 
GTCCAGTTAT CTGTCCCTCC CTACCACCAC GGAGATTCAG TGGAGTTCAC TTGTGCAGAA 
ACCTTCACAA TGATTGGGCA TGCAGTAGTT TTCTGCATTA GTGGAAGGTG GACCGAGCTT 
CCTCAATGTG TTGCAACAGA TCAACTGGAG AAGTGTAAAG CCCCGAAGTC AACTGGCATA 
GATGCAATTC ATCCAAATAA GAATGAATTT AATCATAACT TTAGTGTGAG TTACAGATGT 
AGACAAAAGC AGGAGTATGA ACATTCAATC TGCATCAATG GAAGATGGGA TCCTGAACCA 
AACTGTACAA GAAATGAGAA AAGATTCTGC CCTCCTCCCC CACAGATTCC AAATGCCCAA 
GTGATTGAAA CCACAGTGAA ATACTTGGAT GGAGAGAAAG TATCTGTTCT TTGCCAAGAT 
GGTTACCTAA CTCAGGGCCC AGAAGAAATG GTGTGTAAAC ATGGAAGGTG GCAGTCGTTA 
CCACGCTGCA CGGAAAAAAT TCCATGTTCC CAGCCCCCTA AAATTGAACA TGGATCTATT 
AAGTCGCCCA GGTCCTCAGA AGAGAGAGAT TTAATTGAGT CCAGCAGTTA TGAACACGGA 
ACTACATTCA GCTATGTCTG TGATGATGGA TTCAGGATAT CTGAAGAAAA TAGGGTAACC 
TGCAACATGG GAAAATGGAG CTCTCTGCCT CGTTGTGTTG GAATACCTTG TGGACCCCCA 
CCTTCAATTC CTCTTGGTAT TGTTTCTCAT GAACTAGAAA GTTACCAATA TGGAGAGGAG 
GTTACATACA ATTGTTCTGA AGGCTTTGGA ATTGATGGAC CAGCATTTAT TAAATGTGTA 
GGAGGACAGT GGTCTGAACC ACCCAAATGC ATAAAAACTG ATTGTGACAA CTTGCCCACA 
TTTGAAATTG CCAAACCGAC AGAAAAGAAA AAAAAATCAT ACAGGTCAGG AGAACAAGTG 
ACATTCAGAT GTCCACCTCC GTATCGAATG GATGGCTCTG ACATTGTCAC ATGTGTTAAT 
ACGAAGTGGA TTGGACAGCC GGTATGCAAA GATAATTCCT GTGTGAATCC ACCACATGTG 
CCAAATGCTA CTATACTAAC AAGGCACAAG ACTAAATATC CATCTGGTGA CAAAGTACGT 
TATGACTGTA ATAAACCTTT TGAATTATTT GGGGAAGTGG AAGTGATGTG CCAAAACGGG 
ATTTGGACAG AACCACCGAA ATGCAAAGAT TCAACAGGGA AATGTGGGCC TCCTCCACCT 
ATTGACAATG GAGACATCAC CTCCTTGTCA TTACCAGTAT ATGCACCATT ATCATCAGTT 
GAATATCAAT GCCAGAACTA TTATCTACTT AAGGGAAATA AGATAGTAAC ATGTAGAAAT 
GGAAAGTGGT CTCAGCCACC AACCTGCTTA CATGCATGTG TGATACCAGA AGATATTATG 
GAAAAACATA ATATAGTTCT CAGATGGAGG GAAAATGCAA AGATTTATTC CCAATCAGGG 
GAGAATATTG AATTCATGTG TAAACCTGGA TATAGAAAAT TCAGAGGATC ACCTCCGTTT 
CGTACAAAGT GCATTGAGGG TCACATCAAT TATCCCACTT GTGTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569093.2
CDS	50..3757
Translation	MRLSARIIWLILWTVCVAEDCKGPPPRENSEILSGSWSEQLYSEGTQATYKCRPGYRTLGTIVKVCKNGEWVPSNPSRICRKRPCGHPGDTPFGSFRLAVGSEFEFGAKVVYTCDEGYQLLGEIDYRECDADGWTNDIPICEVVKCLPVTELENGRIVSGAAEPDQEYYFGQVVRFECNSGFKIEGQKEMHCSENGLWSNEKPQCVEISCLPPRVENGDGIYLKPVYKENERFQYKCKQGFVYKERGDAVCTGSGWNPQPSCEEMTCLTPYIPNGIYTPHRIKHRIDDEIRYECKNGFYPATRSPVSKCTITGWIPAPRCSLKPCDFPQFKHGRLYYEESRRPYFPVPIGKEYSYYCDNGFTTPSQSYWDYLRCTVNGWEPEVPCLRQCIFHYVEYGESLYWQRRYIEGQSAKVQCHSGYSLPNGQDTILCTENGWSPPPKCVRIKTCSVSDIEIENGFFSESDYTYALNRKTRYRCKQGYVTNTGEISGIITCLQDGWSPRPSCIKSCDMPVFENAMTKNNNTWFKLNDKLDYECHIGYENEYKHTKGSITCTYDGWSSTPSCYERECSIPLLHQDLVVFPREVKYKVGDSLSFSCRSGHRVGADLVQCYHFGWSPNFPTCEGQVKSCDQPLEIPNGEIKGTKKVEYSHGDVVEYDCKPRFLLKGPNKIQCVDGKWTTLPICVEYERTCGDLPALEHGSVQLSVPPYHHGDSVEFTCAETFTMIGHAVVFCISGRWTELPQCVATDQLEKCKAPKSTGIDAIHPNKNEFNHNFSVSYRCRQKQEYEHSICINGRWDPEPNCTRNEKRFCPPPPQIPNAQVIETTVKYLDGEKVSVLCQDGYLTQGPEEMVCKHGRWQSLPRCTEKIPCSQPPKIEHGSIKSPRSSEERDLIESSSYEHGTTFSYVCDDGFRISEENRVTCNMGKWSSLPRCVGIPCGPPPSIPLGIVSHELESYQYGEEVTYNCSEGFGIDGPAFIKCVGGQWSEPPKCIKTDCDNLPTFEIAKPTEKKKKSYRSGEQVTFRCPPPYRMDGSDIVTCVNTKWIGQPVCKDNSCVNPPHVPNATILTRHKTKYPSGDKVRYDCNKPFELFGEVEVMCQNGIWTEPPKCKDSTGKCGPPPPIDNGDITSLSLPVYAPLSSVEYQCQNYYLLKGNKIVTCRNGKWSQPPTCLHACVIPEDIMEKHNIVLRWRENAKIYSQSGENIEFMCKPGYRKFRGSPPFRTKCIEGHINYPTCV

Target ORF information:

RefSeq Version	NM_130409.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus complement factor H (Cfh), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130409.2

ORF Insert Sequence:

ATGAGACTGT CAGCAAGAAT TATTTGGCTT ATATTATGGA CTGTTTGTGT AGCAGAAGAT 
TGTAAAGGTC CTCCTCCAAG AGAAAATTCA GAAATTCTCT CAGGTTCGTG GTCTGAACAA 
CTATATTCAG AAGGCACTCA GGCAACCTAC AAATGCCGCC CTGGATACCG AACACTTGGT 
ACTATTGTAA AAGTATGCAA GAATGGAGAA TGGGTACCTT CTAACCCATC AAGGATATGT 
CGGAAAAGGC CATGTGGGCA TCCCGGAGAC ACACCCTTTG GGTCCTTTAG GCTGGCAGTT 
GGATCTGAAT TTGAATTTGG TGCAAAGGTT GTTTATACAT GTGATGAAGG GTACCAACTC 
TTAGGTGAAA TTGATTACCG TGAATGTGAT GCAGATGGGT GGACCAATGA TATTCCAATA 
TGTGAAGTTG TGAAGTGCTT GCCAGTGACA GAACTGGAGA ATGGAAGAAT TGTGAGTGGT 
GCAGCCGAAC CAGACCAGGA ATATTATTTT GGACAGGTGG TACGCTTTGA ATGCAACTCC 
GGCTTCAAGA TTGAAGGACA GAAAGAAATG CACTGCTCAG AAAATGGCCT CTGGAGCAAT 
GAAAAGCCAC AGTGTGTGGA AATTTCTTGC CTGCCACCAC GAGTTGAAAA TGGAGATGGT 
ATATATCTGA AACCAGTTTA CAAGGAGAAT GAAAGATTCC AATATAAATG TAAGCAAGGT 
TTTGTGTACA AAGAAAGAGG GGATGCTGTC TGCACGGGTT CTGGATGGAA TCCTCAGCCT 
TCCTGTGAAG AAATGACATG TTTGACTCCA TATATTCCAA ATGGTATCTA CACACCTCAC 
AGGATTAAAC ACAGAATTGA TGATGAAATC AGATATGAAT GTAAAAATGG CTTCTATCCT 
GCAACCCGAT CACCTGTTTC AAAGTGTACA ATTACTGGCT GGATCCCTGC TCCAAGATGT 
AGCTTGAAAC CTTGTGATTT TCCACAATTC AAACATGGAC GTCTGTATTA TGAAGAAAGC 
CGGAGACCCT ACTTCCCAGT ACCTATAGGA AAGGAGTACA GCTATTACTG TGACAACGGG 
TTTACAACGC CTTCACAGTC ATACTGGGAC TACCTTCGTT GCACAGTAAA TGGGTGGGAG 
CCTGAAGTTC CATGCCTCAG GCAATGTATT TTCCATTATG TGGAATATGG AGAATCTTTA 
TACTGGCAAA GAAGATATAT AGAGGGTCAG TCTGCAAAAG TCCAGTGTCA CAGTGGCTAT 
AGTCTTCCAA ATGGTCAAGA TACAATATTA TGTACAGAAA ATGGCTGGTC CCCTCCTCCC 
AAATGCGTCC GTATCAAGAC TTGTTCAGTA TCAGATATAG AAATTGAAAA TGGGTTTTTT 
TCTGAATCTG ATTATACATA TGCTCTAAAT AGAAAAACAC GGTATAGATG TAAACAGGGA 
TATGTAACAA ATACCGGAGA AATATCAGGA ATAATTACTT GTCTTCAAGA TGGATGGTCA 
CCTCGACCCT CATGCATTAA GTCTTGTGAT ATGCCTGTAT TTGAGAATGC TATGACTAAG 
AATAATAACA CATGGTTTAA ACTCAATGAC AAATTAGACT ATGAATGTCA CATTGGATAT 
GAAAATGAAT ATAAACATAC CAAAGGCTCT ATAACATGTA CTTATGATGG ATGGTCTAGT 
ACACCCTCCT GTTATGAAAG AGAATGCAGC ATTCCCCTGT TACACCAAGA CTTAGTTGTT 
TTTCCCAGAG AAGTAAAATA CAAAGTTGGA GATTCGTTGA GTTTCTCTTG CCGTTCAGGA 
CACAGAGTTG GAGCAGATTT AGTGCAATGC TACCACTTTG GATGGTCCCC TAATTTCCCA 
ACGTGTGAAG GCCAAGTAAA ATCATGTGAC CAACCTCTTG AAATCCCGAA TGGGGAAATA 
AAGGGAACAA AAAAAGTTGA ATACAGCCAT GGTGACGTGG TGGAATATGA TTGCAAACCT 
AGATTTCTAC TGAAGGGACC CAATAAAATC CAGTGTGTTG ACGGGAAGTG GACAACCTTG 
CCGATATGCG TTGAGTATGA GAGAACATGT GGAGACCTTC CTGCACTTGA GCATGGCTCT 
GTCCAGTTAT CTGTCCCTCC CTACCACCAC GGAGATTCAG TGGAGTTCAC TTGTGCAGAA 
ACCTTCACAA TGATTGGGCA TGCAGTAGTT TTCTGCATTA GTGGAAGGTG GACCGAGCTT 
CCTCAATGTG TTGCAACAGA TCAACTGGAG AAGTGTAAAG CCCCGAAGTC AACTGGCATA 
GATGCAATTC ATCCAAATAA GAATGAATTT AATCATAACT TTAGTGTGAG TTACAGATGT 
AGACAAAAGC AGGAGTATGA ACATTCAATC TGCATCAATG GAAGATGGGA TCCTGAACCA 
AACTGTACAA GAAATGAGAA AAGATTCTGC CCTCCTCCCC CACAGATTCC AAATGCCCAA 
GTGATTGAAA CCACAGTGAA ATACTTGGAT GGAGAGAAAG TATCTGTTCT TTGCCAAGAT 
GGTTACCTAA CTCAGGGCCC AGAAGAAATG GTGTGTAAAC ATGGAAGGTG GCAGTCGTTA 
CCACGCTGCA CGGAAAAAAT TCCATGTTCC CAGCCCCCTA AAATTGAACA TGGATCTATT 
AAGTCGCCCA GGTCCTCAGA AGAGAGAGAT TTAATTGAGT CCAGCAGTTA TGAACACGGA 
ACTACATTCA GCTATGTCTG TGATGATGGA TTCAGGATAT CTGAAGAAAA TAGGGTAACC 
TGCAACATGG GAAAATGGAG CTCTCTGCCT CGTTGTGTTG GAATACCTTG TGGACCCCCA 
CCTTCAATTC CTCTTGGTAT TGTTTCTCAT GAACTAGAAA GTTACCAATA TGGAGAGGAG 
GTTACATACA ATTGTTCTGA AGGCTTTGGA ATTGATGGAC CAGCATTTAT TAAATGTGTA 
GGAGGACAGT GGTCTGAACC ACCCAAATGC ATAAAAACTG ATTGTGACAA CTTGCCCACA 
TTTGAAATTG CCAAACCGAC AGAAAAGAAA AAAAAATCAT ACAGGTCAGG AGAACAAGTG 
ACATTCAGAT GTCCACCTCC GTATCGAATG GATGGCTCTG ACATTGTCAC ATGTGTTAAT 
ACGAAGTGGA TTGGACAGCC GGTATGCAAA GATAATTCCT GTGTGAATCC ACCACATGTG 
CCAAATGCTA CTATACTAAC AAGGCACAAG ACTAAATATC CATCTGGTGA CAAAGTACGT 
TATGACTGTA ATAAACCTTT TGAATTATTT GGGGAAGTGG AAGTGATGTG CCAAAACGGG 
ATTTGGACAG AACCACCGAA ATGCAAAGAT TCAACAGGGA AATGTGGGCC TCCTCCACCT 
ATTGACAATG GAGACATCAC CTCCTTGTCA TTACCAGTAT ATGCACCATT ATCATCAGTT 
GAATATCAAT GCCAGAACTA TTATCTACTT AAGGGAAATA AGATAGTAAC ATGTAGAAAT 
GGAAAGTGGT CTCAGCCACC AACCTGCTTA CATGCATGTG TGATACCAGA AGATATTATG 
GAAAAACATA ATATAGTTCT CAGATGGAGG GAAAATGCAA AGATTTATTC CCAATCAGGG 
GAGAATATTG AATTCATGTG TAAACCTGGA TATAGAAAAT TCAGAGGATC ACCTCCGTTT 
CGTACAAAGT GCATTGAGGG TCACATCAAT TATCCCACTT GTGTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Disease models & mechanisms11(3)(2018 03)
Li TR,Jia YJ,Ma C,Qiu WY,Wang Q,Shao XQ,Lv RJ

Modulation of miR-146a/complement factor H-mediated inflammatory responses in a rat model of temporal lobe epilepsy.
Bioscience reports36(6)(2016 12)
He F,Liu B,Meng Q,Sun Y,Wang W,Wang C

Circulating AIM prevents hepatocellular carcinoma through complement activation.
Cell reports9(1)61-74(2014 Oct)
Maehara N,Arai S,Mori M,Iwamura Y,Kurokawa J,Kai T,Kusunoki S,Taniguchi K,Ikeda K,Ohara O,Yamamura KI,Miyazaki T

Fusion protein comprising factor H domains 6 and 7 and human IgG1 Fc as an antibacterial immunotherapeutic.
Clinical and vaccine immunology : CVI21(10)1452-9(2014 Oct)
Shaughnessy J,Vu DM,Punjabi R,Serra-Pladevall J,DeOliveira RB,Granoff DM,Ram S

Identification of a Haemophilus influenzae factor H-Binding lipoprotein involved in serum resistance.
Journal of immunology (Baltimore, Md. : 1950)192(12)5913-23(2014 Jun)
Fleury C,Su YC,Hallström T,Sandblad L,Zipfel PF,Riesbeck K

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Cfh cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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