Kcnd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnd1
Entrez Gene ID	116695
Full Name	potassium voltage-gated channel subfamily D member 1
Synonyms	Kv4.1
General protein information	Preferred Names potassium voltage-gated channel subfamily D member 1 Names potassium voltage-gated channel subfamily D member 1 potassium channel, voltage gated Shal-related subfamily D, member 1 potassium voltage gated channel Shal-related family member 1 potassium voltage-gated channel, Shal-related subfamily, member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq12
Summary	human homolog is a voltage-gated potassium channel responsible for inactivating (A-type) currents in the heart and neurons [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105748.1	NP_001099218.1	potassium voltage-gated channel subfamily D member 1 precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	KCND1	XP_001104621.1
Canis lupus familiaris (dog)	KCND1	XP_855372.1
Rattus norvegicus (Norway rat)	Kcnd1	NP_001099218.1
Danio rerio (zebrafish)	kcnd1	NP_001119942.1
Homo sapiens (human)	KCND1	NP_004970.3
Pan troglodytes (chimpanzee)	KCND1	XP_521053.3
Bos taurus (cattle)	KCND1	NP_001019724.1
Mus musculus (house mouse)	Kcnd1	NP_032449.1
Xenopus tropicalis (tropical clawed frog)	LOC100488387	XP_004920307.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.
Dabrowska J, Rainnie DG
Neuroscience171(3)721-33(2010 Dec)

Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neurones.
Kim J, Wei DS, Hoffman DA
The Journal of physiology569(Pt 1)41-57(2005 Nov)

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).
Isbrandt D, Leicher T, Waldschütz R, Zhu X, Luhmann U, Michel U, Sauter K, Pongs O
Genomics64(2)144-54(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kcnd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11307	NM_001105748.1 Latest version!	Rattus norvegicus potassium voltage-gated channel subfamily D member 1 (Kcnd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnd1 ( NM_001105748.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099218.1 Rattus norvegicus potassium voltage-gated channel subfamily D member 1 (Kcnd1), mRNA.

Price & Availability↑

CloneID	ORa11307
Clone ID Related Accession (Same CDS sequence)	NM_001105748.1
Accession Version	NM_001105748.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527350400000
Organism	Rattus norvegicus(Norway rat)
Product	potassium voltage-gated channel subfamily D member 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474078.1. On or before Oct 3, 2007 this sequence version replaced XM_217601.3, XM_001063865.1. ##Evidence-Data-START## Transcript exon combination :: U89873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCAG GTGTGGCCAC ATGGCTACCA TTTGCAAGGG CTGCAGCAGT GGGCTGGCTG 
CCCTTAGCCC AGCAGCCCCT ACCCCCAGCA CCGGAGGTGA AGGCATCCCG AGGGGATGAG 
GTTCTGGTGG TGAACGTGAG TGGTCGGCGC TTTGAAACCT GGAAGAACAC GCTGGATCGC 
TACCCAGACA CATTGCTAGG CAGCTCAGAG AAGGAATTCT TCTATGATGC TGAATCTGGC 
GAGTACTTCT TTGATCGTGA CCCTGACATG TTCCGGCACG TGCTGAACTT TTATCGCACA 
GGCCGACTAC ACTGCCCCAG GCAGGAGTGC ATCCAGGCCT TTGATGAGGA GCTAGCCTTC 
TATGGCTTAG TCCCAGAGCT TGTTGGTGAC TGCTGTCTTG AAGAGTATAG GGACCGCAAG 
AAGGAGAATG CAGAGCGCCT GGCAGAAGAT GAGGAGGCCG AGCAGGCCGG GGAAGGTCCA 
GCCCTTCCAG CAGGCAGCTC CCTGCGACAG CGACTCTGGA GGGCCTTTGA AAACCCACAC 
ACAAGCACTG CAGCACTGGT TTTCTACTAT GTGACTGGCT TCTTTATAGC TGTGTCAGTC 
ATTGCCAACG TAGTGGAGAC CATCCCATGC CGTGGTCCTG CACGGTGGCC CACAAAAGAG 
CAGCCGTGTG GTGACCGCTT CCCTACAGCC TTTTTCTGTA TGGACACGGC CTGTGTGCTC 
ATATTCACCG GGGAATACCT TCTGCGGCTT TTTGCAGCCC CCAGCCGTTG CCGCTTCCTG 
CGTAGTGTTA TGAGCCTCAT CGATGTGGTG GCCATCCTGC CCTACTACAT TGGGCTTTTT 
GTGCCCAAGA ACGATGACGT CTCTGGTGCC TTTGTCACCC TACGTGTGTT TCGGGTCTTC 
CGAATCTTCA AGTTCTCCAG GCACTCCCAG GGCTTGCGGA TTCTGGGCTA CACCCTCAAG 
AGCTGTGCTT CCGAGCTAGG CTTCCTCCTC TTTTCCCTCA CCATGGCTAT CATCATCTTT 
GCCACTGTCA TGTTCTATGC TGAGAAGGGC ACCAGCAAGA CCAACTTCAC AAGCATCCCT 
GCTGCCTTCT GGTATACCAT TGTCACCATG ACCACACTTG GGTATGGCGA CATGGTGCCT 
AGCACCATCG CAGGCAAAAT TTTTGGGTCC ATCTGCTCAC TTAGTGGTGT CTTGGTCATT 
GCCTTGCCTG TACCAGTCAT TGTGTCTAAC TTCAGCCGTA TATACCACCA GAACCAGCGT 
GCTGACAAGC GCCGAGCACA GCAGAAGGTA CGCCTGGCAA GAATCCGGTT GGCAAAGAGT 
GGTACCACCA ACGCCTTCTT GCAGTATAAG CAAAATGGGG GCCTTGAGGA CAGTGGCAGT 
GGGGAGGGAC AGATGCTGTG CGTTAGGAGC CGCTCTGCTT TCGAACAACA GCATCACCAT 
CTGCTGCATT GTTTGGAGAA GACTACGTGT CATGAGTTCA CAGACGAGCT CACTTTCAGT 
GAGGCCCTTG GAGCTGTCTC ACTGGGTGGT CGCACCAGCC GCAGTACCTC AGTATCATCC 
CAGCCAATGG GGCCTGGGAG CCTGTTTTCA TCCTGCTGCT CTAGAAGGGG AGAGCGCAGA 
GCCATCCGCC TTGCCAACTC TACTGCGTCT GTCAGCCGTG GCAGCATGCA GGAGCTAGAC 
ACACTAGCGG GTCTTCGGAG GAGCCCTGCC CCTCAGAGCC GCTCAAGCCT CAATGCCAAG 
CCCCATGACA GCCTTGACCT GAACTGTGAG AGCCGGGACT TCGTGGCTGC CATCATCAGT 
ATCCCCACCC CTCCTGCCAA CACGCCAGAT GAGAGTCAAC CTTCCTCCCC TGGTGGCGGT 
GGCAGTGGTG GCATGGCTAA CACCACCCTC AGGAACTCCA GCTTGGCTAC TCCGTGCCTC 
CTCCCTGAGA CTGTCAAGAT CTCTTCCCTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099218.1
CDS	1..1953
Translation	MAAGVATWLPFARAAAVGWLPLAQQPLPPAPEVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGPARWPTKEQPCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLEDSGSGEGQMLCVRSRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSLGGRTSRSTSVSSQPMGPGSLFSSCCSRRGERRAIRLANSTASVSRGSMQELDTLAGLRRSPAPQSRSSLNAKPHDSLDLNCESRDFVAAIISIPTPPANTPDESQPSSPGGGGSGGMANTTLRNSSLATPCLLPETVKISSL

Target ORF information:

RefSeq Version	NM_001105748.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus potassium voltage-gated channel subfamily D member 1 (Kcnd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105748.1

ORF Insert Sequence:

ATGGCGGCAG GTGTGGCCAC ATGGCTACCA TTTGCAAGGG CTGCAGCAGT GGGCTGGCTG 
CCCTTAGCCC AGCAGCCCCT ACCCCCAGCA CCGGAGGTGA AGGCATCCCG AGGGGATGAG 
GTTCTGGTGG TGAACGTGAG TGGTCGGCGC TTTGAAACCT GGAAGAACAC GCTGGATCGC 
TACCCAGACA CATTGCTAGG CAGCTCAGAG AAGGAATTCT TCTATGATGC TGAATCTGGC 
GAGTACTTCT TTGATCGTGA CCCTGACATG TTCCGGCACG TGCTGAACTT TTATCGCACA 
GGCCGACTAC ACTGCCCCAG GCAGGAGTGC ATCCAGGCCT TTGATGAGGA GCTAGCCTTC 
TATGGCTTAG TCCCAGAGCT TGTTGGTGAC TGCTGTCTTG AAGAGTATAG GGACCGCAAG 
AAGGAGAATG CAGAGCGCCT GGCAGAAGAT GAGGAGGCCG AGCAGGCCGG GGAAGGTCCA 
GCCCTTCCAG CAGGCAGCTC CCTGCGACAG CGACTCTGGA GGGCCTTTGA AAACCCACAC 
ACAAGCACTG CAGCACTGGT TTTCTACTAT GTGACTGGCT TCTTTATAGC TGTGTCAGTC 
ATTGCCAACG TAGTGGAGAC CATCCCATGC CGTGGTCCTG CACGGTGGCC CACAAAAGAG 
CAGCCGTGTG GTGACCGCTT CCCTACAGCC TTTTTCTGTA TGGACACGGC CTGTGTGCTC 
ATATTCACCG GGGAATACCT TCTGCGGCTT TTTGCAGCCC CCAGCCGTTG CCGCTTCCTG 
CGTAGTGTTA TGAGCCTCAT CGATGTGGTG GCCATCCTGC CCTACTACAT TGGGCTTTTT 
GTGCCCAAGA ACGATGACGT CTCTGGTGCC TTTGTCACCC TACGTGTGTT TCGGGTCTTC 
CGAATCTTCA AGTTCTCCAG GCACTCCCAG GGCTTGCGGA TTCTGGGCTA CACCCTCAAG 
AGCTGTGCTT CCGAGCTAGG CTTCCTCCTC TTTTCCCTCA CCATGGCTAT CATCATCTTT 
GCCACTGTCA TGTTCTATGC TGAGAAGGGC ACCAGCAAGA CCAACTTCAC AAGCATCCCT 
GCTGCCTTCT GGTATACCAT TGTCACCATG ACCACACTTG GGTATGGCGA CATGGTGCCT 
AGCACCATCG CAGGCAAAAT TTTTGGGTCC ATCTGCTCAC TTAGTGGTGT CTTGGTCATT 
GCCTTGCCTG TACCAGTCAT TGTGTCTAAC TTCAGCCGTA TATACCACCA GAACCAGCGT 
GCTGACAAGC GCCGAGCACA GCAGAAGGTA CGCCTGGCAA GAATCCGGTT GGCAAAGAGT 
GGTACCACCA ACGCCTTCTT GCAGTATAAG CAAAATGGGG GCCTTGAGGA CAGTGGCAGT 
GGGGAGGGAC AGATGCTGTG CGTTAGGAGC CGCTCTGCTT TCGAACAACA GCATCACCAT 
CTGCTGCATT GTTTGGAGAA GACTACGTGT CATGAGTTCA CAGACGAGCT CACTTTCAGT 
GAGGCCCTTG GAGCTGTCTC ACTGGGTGGT CGCACCAGCC GCAGTACCTC AGTATCATCC 
CAGCCAATGG GGCCTGGGAG CCTGTTTTCA TCCTGCTGCT CTAGAAGGGG AGAGCGCAGA 
GCCATCCGCC TTGCCAACTC TACTGCGTCT GTCAGCCGTG GCAGCATGCA GGAGCTAGAC 
ACACTAGCGG GTCTTCGGAG GAGCCCTGCC CCTCAGAGCC GCTCAAGCCT CAATGCCAAG 
CCCCATGACA GCCTTGACCT GAACTGTGAG AGCCGGGACT TCGTGGCTGC CATCATCAGT 
ATCCCCACCC CTCCTGCCAA CACGCCAGAT GAGAGTCAAC CTTCCTCCCC TGGTGGCGGT 
GGCAGTGGTG GCATGGCTAA CACCACCCTC AGGAACTCCA GCTTGGCTAC TCCGTGCCTC 
CTCCCTGAGA CTGTCAAGAT CTCTTCCCTG TGA