| Gene Symbol | Pitx1 |
| Entrez Gene ID | 113983 |
| Full Name | paired-like homeodomain 1 |
| Synonyms | Bft |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | paired-like homeobox transcription factor; transcription regulator of pituitary genes; genetic marker for nascent Rathke's pouch, precursor of anterior and intermediate lobes of pituitary gland [RGD, Feb 2006]. |
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Pitx1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Pitx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pitx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa10118 Clone ID Related Accession (Same CDS sequence) NM_053624.2 , XM_006253569.3 Accession Version NM_053624.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 948bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1571414400000 Organism Rattus norvegicus(Norway rat) Product pituitary homeobox 1 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061966.1. On Dec 20, 2003 this sequence version replaced NM_053624.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC061966.1, AB047298.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGGACGCCT TCAAGGGAGG CATGAGCCTG GAGAGGCTAC CGGAGGGGCT GCGGCCACCG
CCACCGCCGC CACACGACAT GGGGCCCAGC TTCCACCTGG CCCGCACCGC CGACCCCCGG
GAGCCGCTGG AGAACTCAGC CAGCGAGTCA TCCGACGCCG ATCTGCCAGA CAAGGAGCGC
GGTGGAGAGG CCAAGGTGCC TGAGGATGGC GGCGCGGGCA GCGCTGGCTG CGGCAGCGCG
GAAGACCCAG CCAAGAAGAA GAAACAGCGG CGTCAACGCA CTCACTTCAC AAGCCAGCAG
TTGCAAGAGC TGGAGGCCAC GTTCCAAAGG AACCGCTACC CGGACATGAG CATGAGAGAG
GAGATCGCGG TGTGGACCAA CCTCACTGAG CCGCGAGTGC GGGTCTGGTT CAAGAACCGG
CGAGCCAAGT GGCGCAAGAG GGAGCGGAAC CAGCAGTTGG ACCTGTGCAA GGGCGGCTAC
GTGCCGCAGT TCAGCGGCTT GGTGCAGCCC TACGAGGACG TGTACGCCGC CGCCGGCTAC
TCCTACAACA ACTGGGCCGC CAAGAGCTTG GCACCGGCGC CGCTGTCCAC CAAGAGCTTT
ACCTTCTTCA ACTCCATGAG TCCGCTATCC TCTCAGTCCA TGTTCTCGGC CCCCAGCTCC
ATCTCTTCCA TGACCATGCC ATCCAGCATG GGCCCGGGCT CCGTGCCCGG CATGCCCAAC
TCGGGCCTCA ACAACATCAA CAACCTCACG GGCTCCTCGC TCAACTCGGC CATGTCGCCG
GGCGCCTGCC CCTACGGCAC CCCCGCCTCG CCCTACAGCG TCTACCGGGA CACGTGCAAC
TCGAGCCTCG CCAGCCTGCG GCTCAAGTCC AAGCAGCACT CCTCGTTTGG CTACGGCGGT
CTGCAGGGTC CAGCGTCGGG CCTCAACGCC TGCCAGTATA ACAGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_446076.1 CDS 292..1239 Translation 
Target ORF information:
RefSeq Version NM_053624.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus paired-like homeodomain 1 (Pitx1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_053624.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGGACGCCT TCAAGGGAGG CATGAGCCTG GAGAGGCTAC CGGAGGGGCT GCGGCCACCG
CCACCGCCGC CACACGACAT GGGGCCCAGC TTCCACCTGG CCCGCACCGC CGACCCCCGG
GAGCCGCTGG AGAACTCAGC CAGCGAGTCA TCCGACGCCG ATCTGCCAGA CAAGGAGCGC
GGTGGAGAGG CCAAGGTGCC TGAGGATGGC GGCGCGGGCA GCGCTGGCTG CGGCAGCGCG
GAAGACCCAG CCAAGAAGAA GAAACAGCGG CGTCAACGCA CTCACTTCAC AAGCCAGCAG
TTGCAAGAGC TGGAGGCCAC GTTCCAAAGG AACCGCTACC CGGACATGAG CATGAGAGAG
GAGATCGCGG TGTGGACCAA CCTCACTGAG CCGCGAGTGC GGGTCTGGTT CAAGAACCGG
CGAGCCAAGT GGCGCAAGAG GGAGCGGAAC CAGCAGTTGG ACCTGTGCAA GGGCGGCTAC
GTGCCGCAGT TCAGCGGCTT GGTGCAGCCC TACGAGGACG TGTACGCCGC CGCCGGCTAC
TCCTACAACA ACTGGGCCGC CAAGAGCTTG GCACCGGCGC CGCTGTCCAC CAAGAGCTTT
ACCTTCTTCA ACTCCATGAG TCCGCTATCC TCTCAGTCCA TGTTCTCGGC CCCCAGCTCC
ATCTCTTCCA TGACCATGCC ATCCAGCATG GGCCCGGGCT CCGTGCCCGG CATGCCCAAC
TCGGGCCTCA ACAACATCAA CAACCTCACG GGCTCCTCGC TCAACTCGGC CATGTCGCCG
GGCGCCTGCC CCTACGGCAC CCCCGCCTCG CCCTACAGCG TCTACCGGGA CACGTGCAAC
TCGAGCCTCG CCAGCCTGCG GCTCAAGTCC AAGCAGCACT CCTCGTTTGG CTACGGCGGT
CTGCAGGGTC CAGCGTCGGG CCTCAACGCC TGCCAGTATA ACAGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa10118 Clone ID Related Accession (Same CDS sequence) NM_053624.2 , XM_006253569.3 Accession Version XM_006253569.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 948bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product pituitary homeobox 1 isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006253569.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGGACGCCT TCAAGGGAGG CATGAGCCTG GAGAGGCTAC CGGAGGGGCT GCGGCCACCG
CCACCGCCGC CACACGACAT GGGGCCCAGC TTCCACCTGG CCCGCACCGC CGACCCCCGG
GAGCCGCTGG AGAACTCAGC CAGCGAGTCA TCCGACGCCG ATCTGCCAGA CAAGGAGCGC
GGTGGAGAGG CCAAGGTGCC TGAGGATGGC GGCGCGGGCA GCGCTGGCTG CGGCAGCGCG
GAAGACCCAG CCAAGAAGAA GAAACAGCGG CGTCAACGCA CTCACTTCAC AAGCCAGCAG
TTGCAAGAGC TGGAGGCCAC GTTCCAAAGG AACCGCTACC CGGACATGAG CATGAGAGAG
GAGATCGCGG TGTGGACCAA CCTCACTGAG CCGCGAGTGC GGGTCTGGTT CAAGAACCGG
CGAGCCAAGT GGCGCAAGAG GGAGCGGAAC CAGCAGTTGG ACCTGTGCAA GGGCGGCTAC
GTGCCGCAGT TCAGCGGCTT GGTGCAGCCC TACGAGGACG TGTACGCCGC CGCCGGCTAC
TCCTACAACA ACTGGGCCGC CAAGAGCTTG GCACCGGCGC CGCTGTCCAC CAAGAGCTTT
ACCTTCTTCA ACTCCATGAG TCCGCTATCC TCTCAGTCCA TGTTCTCGGC CCCCAGCTCC
ATCTCTTCCA TGACCATGCC ATCCAGCATG GGCCCGGGCT CCGTGCCCGG CATGCCCAAC
TCGGGCCTCA ACAACATCAA CAACCTCACG GGCTCCTCGC TCAACTCGGC CATGTCGCCG
GGCGCCTGCC CCTACGGCAC CCCCGCCTCG CCCTACAGCG TCTACCGGGA CACGTGCAAC
TCGAGCCTCG CCAGCCTGCG GCTCAAGTCC AAGCAGCACT CCTCGTTTGG CTACGGCGGT
CTGCAGGGTC CAGCGTCGGG CCTCAACGCC TGCCAGTATA ACAGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_006253631.1 CDS 110..1057 Translation
Target ORF information:
RefSeq Version XM_006253569.3 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus paired-like homeodomain 1 (Pitx1), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_006253569.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGGACGCCT TCAAGGGAGG CATGAGCCTG GAGAGGCTAC CGGAGGGGCT GCGGCCACCG
CCACCGCCGC CACACGACAT GGGGCCCAGC TTCCACCTGG CCCGCACCGC CGACCCCCGG
GAGCCGCTGG AGAACTCAGC CAGCGAGTCA TCCGACGCCG ATCTGCCAGA CAAGGAGCGC
GGTGGAGAGG CCAAGGTGCC TGAGGATGGC GGCGCGGGCA GCGCTGGCTG CGGCAGCGCG
GAAGACCCAG CCAAGAAGAA GAAACAGCGG CGTCAACGCA CTCACTTCAC AAGCCAGCAG
TTGCAAGAGC TGGAGGCCAC GTTCCAAAGG AACCGCTACC CGGACATGAG CATGAGAGAG
GAGATCGCGG TGTGGACCAA CCTCACTGAG CCGCGAGTGC GGGTCTGGTT CAAGAACCGG
CGAGCCAAGT GGCGCAAGAG GGAGCGGAAC CAGCAGTTGG ACCTGTGCAA GGGCGGCTAC
GTGCCGCAGT TCAGCGGCTT GGTGCAGCCC TACGAGGACG TGTACGCCGC CGCCGGCTAC
TCCTACAACA ACTGGGCCGC CAAGAGCTTG GCACCGGCGC CGCTGTCCAC CAAGAGCTTT
ACCTTCTTCA ACTCCATGAG TCCGCTATCC TCTCAGTCCA TGTTCTCGGC CCCCAGCTCC
ATCTCTTCCA TGACCATGCC ATCCAGCATG GGCCCGGGCT CCGTGCCCGG CATGCCCAAC
TCGGGCCTCA ACAACATCAA CAACCTCACG GGCTCCTCGC TCAACTCGGC CATGTCGCCG
GGCGCCTGCC CCTACGGCAC CCCCGCCTCG CCCTACAGCG TCTACCGGGA CACGTGCAAC
TCGAGCCTCG CCAGCCTGCG GCTCAAGTCC AAGCAGCACT CCTCGTTTGG CTACGGCGGT
CTGCAGGGTC CAGCGTCGGG CCTCAACGCC TGCCAGTATA ACAGCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Functional characterization of a human POU1F1 mutation associated with isolated growth hormone deficiency: a novel etiology for IGHD.
Human molecular genetics25(3)472-83(2016 Feb)
Sobrier ML,Tsai YC,Pérez C,Leheup B,Bouceba T,Duquesnoy P,Copin B,Sizova D,Penzo A,Stanger BZ,Cooke NE,Liebhaber SA,Amselem S
The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons.
Molecular and cellular neurosciences68272-83(2015 Sep)
Simpson MT,Venkatesh I,Callif BL,Thiel LK,Coley DM,Winsor KN,Wang Z,Kramer AA,Lerch JK,Blackmore MG
In vivo oestrogenic modulation of Egr1 and Pitx1 gene expression in female rat pituitary gland.
Journal of molecular endocrinology53(3)355-66(2014 Dec)
Gajewska A,Herman AP,Wolińska-Witort E,Kochman K,Zwierzchowski L
Pitx1 is necessary for normal initiation of hindlimb outgrowth through regulation of Tbx4 expression and shapes hindlimb morphologies via targeted growth control.
Development (Cambridge, England)138(24)5301-9(2011 Dec)
Duboc V,Logan MP
Identification of PITX1 as a TERT suppressor gene located on human chromosome 5.
Molecular and cellular biology31(8)1624-36(2011 Apr)
Qi DL,Ohhira T,Fujisaki C,Inoue T,Ohta T,Osaki M,Ohshiro E,Seko T,Aoki S,Oshimura M,Kugoh H
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