Atp1a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Atp1a2
Entrez Gene ID	98660
Full Name	ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms	AW060654,Atpa-3,mKIAA0778
General protein information	Preferred Names ATPase, Na+/K+ transporting, alpha 2 polypeptide Names sodium/potassium-transporting ATPase subunit alpha-2 Na(+)/K(+) ATPase alpha(+) subunit Na(+)/K(+) ATPase alpha-2 subunit sodium pump subunit alpha-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H3\|1 79.6 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_178405.3	NP_848492.1	sodium/potassium-transporting ATPase subunit alpha-2 precursor

Pathways from BioSystems

Homologies

Magnaporthe oryzae (rice blast fungus)	MGG_16361	XP_003710305.1
Bos taurus (cattle)	ATP1A2	NP_001074993.1
Rattus norvegicus (Norway rat)	Atp1a2	NP_036637.1
Macaca mulatta (Rhesus monkey)	ATP1A2	XP_001115318.2
Canis lupus familiaris (dog)	ATP1A2	XP_545753.3
Mus musculus (house mouse)	Atp1a2	NP_848492.1
Homo sapiens (human)	ATP1A2	NP_000693.1
Gallus gallus (chicken)	ATP1A2	NP_990807.1
Danio rerio (zebrafish)	atp1a2a	NP_571758.1
Magnaporthe oryzae (rice blast fungus)	MGG_10027	XP_003717477.1
Pan troglodytes (chimpanzee)	ATP1A2	XP_513921.2
Xenopus tropicalis (tropical clawed frog)	atp1a2	NP_001096439.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.
Kros L, Lykke-Hartmann K, Khodakhah K
Scientific reports8(1)16959(2018 11)

The α2β2 isoform combination dominates the astrocytic Na
Stoica A, Larsen BR, Assentoft M, Holm R, Holt LM, Vilhardt F, Vilsen B, Lykke-Hartmann K, Olsen ML, MacAulay N
Glia65(11)1777-1793(2017 11)

The loss-of-function disease-mutation G301R in the Na
Ellman DG, Isaksen TJ, Lund MC, Dursun S, Wirenfeldt M, Jørgensen LH, Lykke-Hartmann K, Lambertsen KL
BMC neuroscience18(1)66(2017 09)

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
Heng X, Guo Q, Leung AW, Li JY
eLife6(2017 05)

Atp1a2 contributes modestly to alcohol-related behaviors.
Gritz SM, Larson C, Radcliffe RA
Alcohol (Fayetteville, N.Y.)5629-37(2016 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Atp1a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Atp1a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu17913	NM_178405.3 Latest version!	Mus musculus ATPase, Na+/K+ transporting, alpha 2 polypeptide (Atp1a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Atp1a2 ( NM_178405.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848492.1 Mus musculus ATPase, Na+/K+ transporting, alpha 2 polypeptide (Atp1a2), mRNA.

Price & Availability↑

CloneID	OMu17913
Clone ID Related Accession (Same CDS sequence)	NM_178405.3
Accession Version	NM_178405.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3063bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	sodium/potassium-transporting ATPase subunit alpha-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY780072.1, AK147331.1 and AC087061.22. On Jan 28, 2006 this sequence version replaced NM_178405.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147331.1, AK161840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTCGTG GGGCAGGGCG TGAGTACTCG CCTGCTGCCA CCACTGCGGA AAATGGGGGT 
GGCAAGAAGA AACAGAAAGA GAAGGAGCTC GATGAGCTGA AGAAGGAGGT TGCCATGGAT 
GACCACAAGC TGTCCTTGGA TGAGCTGGGC CGAAAATACC AAGTGGATCT GTCTAAGGGC 
CTCACCAATC AGCGAGCTCA GGACATTCTG GCTAGAGATG GACCCAACGC CCTTACTCCG 
CCCCCCACAA CTCCTGAGTG GGTCAAGTTC TGTCGTCAGC TTTTTGGGGG CTTCTCTATC 
CTGCTGTGGA TTGGGGCACT CCTCTGCTTC TTAGCCTATG GTATCCTGGC CGCTATGGAG 
GACGAACCAT CCAACGATAA TTTATATCTA GGTATCGTGC TAGCGGCTGT AGTTATCGTC 
ACCGGCTGCT TCTCCTACTA CCAGGAAGCC AAGAGCTCCA AGATCATGGA CTCCTTCAAG 
AACATGGTGC CTCAGCAAGC TCTGGTCATC CGAGAGGGAG AAAAGATGCA GATCAATGCA 
GAGGAGGTGG TGGTGGGAGA CCTGGTGGAG GTGAAGGGTG GAGACCGTGT CCCTGCTGAC 
CTCCGGATCA TCTCTTCCCA CGGTTGCAAG GTGGATAACT CATCCCTAAC AGGGGAGTCG 
GAGCCCCAGA CCCGTTCTCC TGAGTTCACC CACGAGAACC CCTTGGAGAC GCGCAATATC 
TGTTTCTTCT CTACCAACTG CGTGGAAGGC ACTGCCAGGG GCATTGTGAT TGCCACAGGT 
GACCGGACAG TGATGGGCCG CATAGCCACT CTTGCCTCTG GCCTAGAGGT GGGACAGACA 
CCCATAGCCA TGGAGATCGA GCATTTCATC CAGCTGATCA CAGGGGTGGC TGTGTTCCTG 
GGGGTCTCCT TCTTCGTTCT GTCCCTCATC CTGGGCTACA GCTGGCTGGA GGCAGTCATC 
TTCCTCATCG GCATCATCGT AGCCAATGTG CCCGAAGGGC TGTTGGCCAC CGTGACTGTG 
TGCCTGACGC TGACAGCCAA GCGCATGGCT CGCAAAAACT GCCTGGTGAA GAACCTGGAG 
GCCGTGGAGA CGCTGGGCTC CACGTCCACC ATCTGCTCAG ACAAGACGGG CACCCTCACC 
CAGAACCGCA TGACAGTGGC TCACATGTGG TTTGACAACC AGATCCATGA GGCTGACACC 
ACAGAGGACC AGTCTGGGGC CACTTTTGAC AAACGGTCCC CCACATGGAC AGCCCTGTCT 
CGGATCGCTG GTCTCTGCAA TCGTGCTGTC TTCAAGGCTG GACAAGAGAA CATCTCCGTG 
TCTAAGCGGG ACACAGCTGG AGATGCTTCT GAGTCAGCTC TGCTCAAGTG CATTGAGCTG 
TCCTGTGGCT CAGTGAGGAA GATGAGGGAC AGGAACCCTA AGGTGGCAGA AATCCCCTTC 
AACTCCACCA ACAAATATCA GCTCTCCATC CACGAGAGGG AAGACAGTCC CCAGAGCCAT 
GTGCTGGTGA TGAAAGGCGC CCCAGAGCGC ATCCTGGACC GATGCTCCAC CATCCTGGTA 
CAGGGCAAGG AGATCCCTCT TGACAAGGAG ATGCAAGATG CTTTTCAAAA CGCCTACATG 
GAGCTGGGAG GACTTGGGGA ACGAGTGCTG GGCTTCTGTC AGCTGAACCT GCCTTCTGGA 
AAGTTTCCTC GGGGCTTCAA ATTTGATACA GATGAGCTGA ACTTTCCCAC AGAGAAGCTC 
TGTTTTGTGG GGCTCATGTC TATGATTGAT CCCCCCAGAG CAGCCGTGCC GGATGCCGTG 
GGCAAGTGCC GAAGCGCGGG CATCAAGGTG ATCATGGTGA CCGGGGATCA CCCCATCACA 
GCTAAGGCCA TTGCCAAAGG TGTGGGCATC ATATCAGAGG GTAACGAGAC TGTGGAAGAC 
ATTGCAGCCA GGCTCAACAT TCCTGTGAGT CAAGTCAATC CCAGAGAAGC CAAGGCGTGT 
GTAGTGCACG GCTCAGACCT GAAGGACATG ACGTCAGAGC AGCTGGATGA GATCCTCAGG 
GACCACACGG AGATTGTCTT TGCCCGGACC TCCCCTCAGC AGAAGCTTAT CATTGTGGAA 
GGGTGTCAGA GGCAGGGAGC CATTGTGGCA GTGACTGGTG ACGGGGTGAA CGACTCCCCC 
GCGCTGAAGA AGGCTGACAT TGGCATTGCC ATGGGCATCT CCGGCTCCGA TGTCTCTAAG 
CAGGCGGCTG ACATGATCCT TCTCGACGAC AACTTTGCCT CCATTGTGAC AGGCGTGGAG 
GAGGGCCGCC TGATCTTTGA CAACTTGAAG AAGTCCATCG CATACACCCT GACCAGCAAC 
ATCCCTGAGA TCACCCCCTT CCTGCTGTTC ATCATTGCCA ACATCCCCCT TCCACTGGGC 
ACTGTGACCA TCCTCTGCAT CGACCTGGGG ACAGATATGG TTCCTGCTAT CTCATTAGCA 
TACGAAGCAG CTGAGAGTGA CATCATGAAG AGGCAGCCAC GAAACTCCCA GACAGACAAG 
CTGGTGAACG AGAGGCTTAT CAGCATGGCT TACGGACAGA TTGGCATGAT CCAGGCTCTG 
GGTGGCTTCT TTACCTACTT TGTGATACTG GCAGAGAATG GGTTTCTACC ATCGCGGCTG 
CTAGGGATCC GCCTGGACTG GGATGATCGG ACTACCAACG ACCTGGAGGA CAGCTATGGA 
CAAGAGTGGA CCTACGAGCA GCGGAAGGTG GTGGAGTTCA CATGCCACAC GGCCTTCTTC 
GCTAGCATCG TGGTTGTGCA GTGGGCTGAC CTCATCATCT GCAAGACCCG TCGCAACTCA 
GTGTTCCAGC AGGGCATGAA GAACAAGATC CTGATTTTTG GGCTGCTAGA AGAGACGGCT 
TTGGCTGCCT TTCTGTCTTA CTGCCCGGGC ATGGGGGTTG CCCTCCGGAT GTACCCACTC 
AAGGTCACGT GGTGGTTCTG TGCCTTCCCC TACAGTCTCC TCATCTTCAT CTATGATGAA 
GTTCGGAAGC TCATCCTACG GCGGTACCCT GGGGGCTGGG TGGAGAAGGA GACGTACTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848492.1
CDS	173..3235
Translation	MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDEPSNDNLYLGIVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY

Target ORF information:

RefSeq Version	NM_178405.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATPase, Na+/K+ transporting, alpha 2 polypeptide (Atp1a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178405.3

ORF Insert Sequence:

ATGGGTCGTG GGGCAGGGCG TGAGTACTCG CCTGCTGCCA CCACTGCGGA AAATGGGGGT 
GGCAAGAAGA AACAGAAAGA GAAGGAGCTC GATGAGCTGA AGAAGGAGGT TGCCATGGAT 
GACCACAAGC TGTCCTTGGA TGAGCTGGGC CGAAAATACC AAGTGGATCT GTCTAAGGGC 
CTCACCAATC AGCGAGCTCA GGACATTCTG GCTAGAGATG GACCCAACGC CCTTACTCCG 
CCCCCCACAA CTCCTGAGTG GGTCAAGTTC TGTCGTCAGC TTTTTGGGGG CTTCTCTATC 
CTGCTGTGGA TTGGGGCACT CCTCTGCTTC TTAGCCTATG GTATCCTGGC CGCTATGGAG 
GACGAACCAT CCAACGATAA TTTATATCTA GGTATCGTGC TAGCGGCTGT AGTTATCGTC 
ACCGGCTGCT TCTCCTACTA CCAGGAAGCC AAGAGCTCCA AGATCATGGA CTCCTTCAAG 
AACATGGTGC CTCAGCAAGC TCTGGTCATC CGAGAGGGAG AAAAGATGCA GATCAATGCA 
GAGGAGGTGG TGGTGGGAGA CCTGGTGGAG GTGAAGGGTG GAGACCGTGT CCCTGCTGAC 
CTCCGGATCA TCTCTTCCCA CGGTTGCAAG GTGGATAACT CATCCCTAAC AGGGGAGTCG 
GAGCCCCAGA CCCGTTCTCC TGAGTTCACC CACGAGAACC CCTTGGAGAC GCGCAATATC 
TGTTTCTTCT CTACCAACTG CGTGGAAGGC ACTGCCAGGG GCATTGTGAT TGCCACAGGT 
GACCGGACAG TGATGGGCCG CATAGCCACT CTTGCCTCTG GCCTAGAGGT GGGACAGACA 
CCCATAGCCA TGGAGATCGA GCATTTCATC CAGCTGATCA CAGGGGTGGC TGTGTTCCTG 
GGGGTCTCCT TCTTCGTTCT GTCCCTCATC CTGGGCTACA GCTGGCTGGA GGCAGTCATC 
TTCCTCATCG GCATCATCGT AGCCAATGTG CCCGAAGGGC TGTTGGCCAC CGTGACTGTG 
TGCCTGACGC TGACAGCCAA GCGCATGGCT CGCAAAAACT GCCTGGTGAA GAACCTGGAG 
GCCGTGGAGA CGCTGGGCTC CACGTCCACC ATCTGCTCAG ACAAGACGGG CACCCTCACC 
CAGAACCGCA TGACAGTGGC TCACATGTGG TTTGACAACC AGATCCATGA GGCTGACACC 
ACAGAGGACC AGTCTGGGGC CACTTTTGAC AAACGGTCCC CCACATGGAC AGCCCTGTCT 
CGGATCGCTG GTCTCTGCAA TCGTGCTGTC TTCAAGGCTG GACAAGAGAA CATCTCCGTG 
TCTAAGCGGG ACACAGCTGG AGATGCTTCT GAGTCAGCTC TGCTCAAGTG CATTGAGCTG 
TCCTGTGGCT CAGTGAGGAA GATGAGGGAC AGGAACCCTA AGGTGGCAGA AATCCCCTTC 
AACTCCACCA ACAAATATCA GCTCTCCATC CACGAGAGGG AAGACAGTCC CCAGAGCCAT 
GTGCTGGTGA TGAAAGGCGC CCCAGAGCGC ATCCTGGACC GATGCTCCAC CATCCTGGTA 
CAGGGCAAGG AGATCCCTCT TGACAAGGAG ATGCAAGATG CTTTTCAAAA CGCCTACATG 
GAGCTGGGAG GACTTGGGGA ACGAGTGCTG GGCTTCTGTC AGCTGAACCT GCCTTCTGGA 
AAGTTTCCTC GGGGCTTCAA ATTTGATACA GATGAGCTGA ACTTTCCCAC AGAGAAGCTC 
TGTTTTGTGG GGCTCATGTC TATGATTGAT CCCCCCAGAG CAGCCGTGCC GGATGCCGTG 
GGCAAGTGCC GAAGCGCGGG CATCAAGGTG ATCATGGTGA CCGGGGATCA CCCCATCACA 
GCTAAGGCCA TTGCCAAAGG TGTGGGCATC ATATCAGAGG GTAACGAGAC TGTGGAAGAC 
ATTGCAGCCA GGCTCAACAT TCCTGTGAGT CAAGTCAATC CCAGAGAAGC CAAGGCGTGT 
GTAGTGCACG GCTCAGACCT GAAGGACATG ACGTCAGAGC AGCTGGATGA GATCCTCAGG 
GACCACACGG AGATTGTCTT TGCCCGGACC TCCCCTCAGC AGAAGCTTAT CATTGTGGAA 
GGGTGTCAGA GGCAGGGAGC CATTGTGGCA GTGACTGGTG ACGGGGTGAA CGACTCCCCC 
GCGCTGAAGA AGGCTGACAT TGGCATTGCC ATGGGCATCT CCGGCTCCGA TGTCTCTAAG 
CAGGCGGCTG ACATGATCCT TCTCGACGAC AACTTTGCCT CCATTGTGAC AGGCGTGGAG 
GAGGGCCGCC TGATCTTTGA CAACTTGAAG AAGTCCATCG CATACACCCT GACCAGCAAC 
ATCCCTGAGA TCACCCCCTT CCTGCTGTTC ATCATTGCCA ACATCCCCCT TCCACTGGGC 
ACTGTGACCA TCCTCTGCAT CGACCTGGGG ACAGATATGG TTCCTGCTAT CTCATTAGCA 
TACGAAGCAG CTGAGAGTGA CATCATGAAG AGGCAGCCAC GAAACTCCCA GACAGACAAG 
CTGGTGAACG AGAGGCTTAT CAGCATGGCT TACGGACAGA TTGGCATGAT CCAGGCTCTG 
GGTGGCTTCT TTACCTACTT TGTGATACTG GCAGAGAATG GGTTTCTACC ATCGCGGCTG 
CTAGGGATCC GCCTGGACTG GGATGATCGG ACTACCAACG ACCTGGAGGA CAGCTATGGA 
CAAGAGTGGA CCTACGAGCA GCGGAAGGTG GTGGAGTTCA CATGCCACAC GGCCTTCTTC 
GCTAGCATCG TGGTTGTGCA GTGGGCTGAC CTCATCATCT GCAAGACCCG TCGCAACTCA 
GTGTTCCAGC AGGGCATGAA GAACAAGATC CTGATTTTTG GGCTGCTAGA AGAGACGGCT 
TTGGCTGCCT TTCTGTCTTA CTGCCCGGGC ATGGGGGTTG CCCTCCGGAT GTACCCACTC 
AAGGTCACGT GGTGGTTCTG TGCCTTCCCC TACAGTCTCC TCATCTTCAT CTATGATGAA 
GTTCGGAAGC TCATCCTACG GCGGTACCCT GGGGGCTGGG TGGAGAAGGA GACGTACTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.
Scientific reports8(1)16959(2018 11)
Kros L,Lykke-Hartmann K,Khodakhah K

The α2β2 isoform combination dominates the astrocytic Na
Glia65(11)1777-1793(2017 11)
Stoica A,Larsen BR,Assentoft M,Holm R,Holt LM,Vilhardt F,Vilsen B,Lykke-Hartmann K,Olsen ML,MacAulay N

The loss-of-function disease-mutation G301R in the Na
BMC neuroscience18(1)66(2017 09)
Ellman DG,Isaksen TJ,Lund MC,Dursun S,Wirenfeldt M,Jørgensen LH,Lykke-Hartmann K,Lambertsen KL

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
eLife6(2017 05)
Heng X,Guo Q,Leung AW,Li JY

Atp1a2 contributes modestly to alcohol-related behaviors.
Alcohol (Fayetteville, N.Y.)5629-37(2016 11)
Gritz SM,Larson C,Radcliffe RA

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Atp1a2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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