Abca12 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abca12
Entrez Gene ID	74591
Full Name	ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms	4832428G11Rik,4833417A11Rik
General protein information	Preferred Names ATP-binding cassette, sub-family A (ABC1), member 12 Names ATP-binding cassette sub-family A member 12
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_175210.3	NP_780419.2	ATP-binding cassette sub-family A member 12

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Abca12	XP_237242.6
Xenopus tropicalis (tropical clawed frog)	abca12	XP_004918315.1
Xenopus tropicalis (tropical clawed frog)	LOC101731410	XP_004918316.1
Canis lupus familiaris (dog)	ABCA12	XP_536058.2
Gallus gallus (chicken)	ABCA12	XP_421867.4
Danio rerio (zebrafish)	abca12	XP_686632.6
Homo sapiens (human)	ABCA12	NP_775099.2
Pan troglodytes (chimpanzee)	ABCA12	XP_001149722.1
Macaca mulatta (Rhesus monkey)	ABCA12	XP_001084970.2
Bos taurus (cattle)	ABCA12	NP_001178223.2
Mus musculus (house mouse)	Abca12	NP_780419.2

Gene Ontology
Bibliography

Related articles in PubMed

PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opálka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N
Human molecular genetics26(10)1787-1800(2017 05)

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR
PloS one11(8)e0161465(2016)

Variant mapping and mutation discovery in inbred mice using next-generation sequencing.
Gallego-Llamas J, Timms AE, Geister KA, Lindsay A, Beier DR
BMC genomics16913(2015 Nov)

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis.
Cottle DL, Ursino GM, Ip SC, Jones LK, Ditommaso T, Hacking DF, Mangan NE, Mellett NA, Henley KJ, Sviridov D, Nold-Petry CA, Nold MF, Meikle PJ, Kile BT, Smyth IM
Human molecular genetics24(2)436-49(2015 Jan)

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.
Haller JF, Cavallaro P, Hernandez NJ, Dolat L, Soscia SJ, Welti R, Grabowski GA, Fitzgerald ML, Freeman MW
Journal of lipid research55(3)493-503(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abca12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abca12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18323	NM_175210.3 Latest version!	Mus musculus ATP-binding cassette, sub-family A (ABC1), member 12 (Abca12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	29-31	$1301.30 $1859.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abca12 ( NM_175210.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_780419.2 Mus musculus ATP-binding cassette, sub-family A (ABC1), member 12 (Abca12), mRNA.

Price & Availability↑

CloneID	OMu18323
Clone ID Related Accession (Same CDS sequence)	NM_175210.3
Accession Version	NM_175210.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7788bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527350400000
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family A member 12
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC138589.16 and AC107789.7. On or before Mar 28, 2009 this sequence version replaced XM_987225.1, XM_001002308.2, NM_175210.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC158053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCC AGTTTCATCA GCTTCGGATC CTGGTGTGGA AAAATTGGCT AGGTGTCAAA 
AGGCAGCCGC TTTGGACACT TGTCTTGATC TTATGGCCAG TCATTATTTT CATAATTCTG 
GCTATTACCC GGACAAAATT CCCGCCAACA GCAAAACCAA CTTGTTACCT CGCACCTCGA 
AACCTTCCCA GTGCTGGATT CTTCCCATTC CTACAAACCC TGCTCTGTGA CACAGACTCT 
AAATGTAAAG ACACGCCCTA TGGACCACGA GATCTGCTCC GCAGGAAGGG GATTGATGGA 
CCGCTATTTA AAGAAAGCGA AATTCTGAAA AAGCCGTCCA ACCCGAAGAG GGACAGCAAT 
TTATCACTCC GGAGCACCCA AGTTCCAGAA AGAAGTCACA CATCATTGGC CACAGTACCT 
CCAAGACCAA GCTATGATTT GGAAGGAACA GGCACAGAAA ATTTCAATGG TAGCCAATTG 
CTTACACGCA TCCTTGGTTT GGAAAAGCTG CTGAAGCAAA ATTCAACTCC AGAAGACATA 
CGAAGAGAGC TGTGTGAGAG CTACCCTGGG TACACTGCGG ACTATGCCTT CTCTTGGGTC 
ACCCTAGGAA AAAACGTTTT TAACAAATTT TGCCTTTCGA ACATGACACT TTTAGAGTCT 
TCACTCCAGG AACTAAAATA TCAAGTCTCT CAGATGTCAA GTGACCCCGA CAATCAGAAG 
AGGGTGTTCC GGGGACTTGT CCAGGTGCTG TCCTTTTTCT CTCAAGTGCA GCAGCAAAGA 
GAAGTGTGGC AACTTCTGTC GAGCTTACCA GATGTGTTTC AGAATGGCAC CTCATTGAGC 
AGTCTATTTG GTGTTCTTCA AAAGGCAAAC AGGGTGCTGC TGGTAGTGCA GAAGGTTTAC 
CCACGTGTTC AAACTGATGA AGGATTCAGC ACCCTCCAGA AGTCTGTTAA ACATCTGCTG 
AACACTCTGG ACTCCCCAAT GCAAGGTGAC AATTCAACGC ACGCATGGAG TGATGATGAT 
GAGCAGACAC TGTCCCCGAG CAGTCTGGCT GCACAGCTCC TGATCCTGGA AAACTTTGAA 
GATGCCATCT TGAACATATC ATCAAATAGT CCATATTCTC CTTATTTGGC GTGTGTAAGG 
AACATGACTG ACAACTTGGC TAAGGGATCA CCAGACAATC TAAAACTTCT GCAGTCCACA 
ATTCACTTCA GAAAATCTTT CCTTCAAAAT GGCTCCTCCG AGGACAGCTT CCCTCCATTT 
CTTGAGATCC TGAAATCCAA GCTGTCTCAA CTTCGAAATT TGACGGAACT TCTCTGCGAA 
TCAGAGACTT TCAGTTCGAT CAAGAAGTCT TGCCAGTTCT CTAACATGAG CTTCGAGAGG 
CTGTGTGAAG ACCATGCCTT TCACGTGCAA CTGATTGAAG CGGCAGAGCT GGGCACTGAC 
CTCACCACTG GCTTACTGTA CCATGACAAT ATAATATCTG CAAAGCTGAG GGGTTTGCTC 
ACTGGAGATC CCAGCAAAAT TAATCTCAAT GTGGACTGGC TCCTGGAACA GGCATTGCAA 
ATGAATTACT TGGAGAATAT CACACGGCTC ATACCAACCG TAGAGGCCAT GCTGCATGTC 
AACACCAGTG CAGACGCTTC TGAGAAGCCA GGTCAATTAA GAGAAATGTT TAAAAACATA 
GATTTGCTGA AAGAAGATCT GAGGGCGATA GGGATGTCCA ACACAAGTAT CGACAAGCTG 
TTGGCCATTC CCATTCCAGA CAATAGAGCC GAGATAATTT CTCGTGTATT CTGGTTGCAC 
TCATGTGATA CCAACGTCAC CAACCCCAAA CTGGAAGATG CCATGAAGGA GTTCTGCAAG 
CTGCCTCTTC CAGAGAGATC ACATCAGTCC TACCTCATCG GACTCACCCT TCTGCACTAC 
TTAGACATTT ACAATTTCAC ATACAAGGTG TTTTTCCCAA GGAAGGATCA AAAGCCAATG 
GAAAGGATGA TGGAGCTTTT CATAAAGCTG AGAGAGATTC TCAATCAGTT GGCTTCCGGC 
ACACATCCAC TGCTGGACAA AATGAGATCC CTGAGACAAA TGCACCTGCC CAGGAGTGTT 
CCATTAACAC AGGCCATGTA CAGAAACACT CGAATGAACT CGCCAGCAGG ATCGTTCAGT 
ACTATCTCCC AGGCTCTGTG CTCCCAGGGG ATCACCACCG AGTACTTAAC TGCTATGCTG 
CCTTCTTCCC AGAAGCCAAA AGGCAACCAC ACCAAGGATT TTCTCACTTA TAAATTAACT 
AAAGAAGAAA TTGCTTCAAA ATACGGGATT CCTTTAAATG CTACACCATT TTGCTTCTCC 
CTTTACAAAG ACATCATTAA CATGCCTGCT GGGCCTGTGA TTTGGGCCTT CTTGAAACCC 
ATGTTGTTGG GAAAGATTTT ATATTCACCA TATAACCCAA CTACAAAGGC CATTATGGAA 
AAGTCCAATG TAACTCTAAG ACAGCTGGCG GAATTAAGAG AAAAATCTCA GGAGTGGATG 
GATAAGTCAC CAATTTTCAT GAATTCCTTC CACCTGCTAA ACCAGACGAT CCCAATGCTC 
CAGAATACTC TACGGAACCC CTTTGTGCAA GTTTTTGTGA AGTTCTCCGT GGGACTCGAT 
GCTGTCGAAC TCCTGAAGCA GATAGACGAC CTTGATGTTC TCAGGCTGAA ATTAGTGAAC 
AACATTGACA TCATTGATCA GCTCAACACA CTGTCTTCCC TGACTGTAAA TATTTCCTCC 
TGTGTTCTTT ACGACCGTAT TCAGGCGTCA GACACTGTAG AGGAGATGGA GACGGTGGCC 
GAACAACTCT ACAAGAGCAA CGAGCTCTTT GGAAGTGTCA TTTTTAAGCT TCCATCTAAC 
GGAAGTTTGC ACAGAGGGTT TGACCCTGAA AAAGTGTCTC TTCCTCCTAT CGTAAGATAT 
ACCATCCGCA TGAGTCTGAA GACGGCACAG ACCACAAGGA GCATAAGAAC AAAGATCTGG 
GCCCCAGGGC CACACAACTC TCCATCCCAT AACCAGATCT ATGGCCGGGC TTTCATTTAT 
CTGCAGGATA GCATTGAGAG AGCAATTATT GAGTTACAAA CAGGAAGGAA CTCACAGGAA 
GTCGCCGTCC AGGTTCAAGC GGTTCCTTAT CCCTGCTTCA TGAAGGACAA TTTCCTCACC 
AGTGTCTCCT ATTCCCTCCC GATTGTGCTT ATGGTCGCCT GGGTTGTATT TATAGCTGCC 
TTTGTTAAAA AGCTAGTCTA CGAGAAGGAC CTTCGGCTCC ATGAGTACAT GAAGATGATG 
GGTGTCAACT CCTGCAGCCA TTTCTTTGCC TGGCTTATAG AGAGTATTGG GTTCTTGCTG 
GTCACCATTG CAATCCTCAT CGTTATCCTC AAGTTTGGCA ATATTCTTCC CAAGACAAAC 
GGCTTCATTT TGTTCCTGTA CTTCTCAGAC TACAGCTTCT CAGTGATTGC CATGAGCTAT 
CTCATCAGTG TCTTCTTCAA CAACACCAAC ATTGCAGCTC TGATTGGAAG CCTCATCTAT 
GTCATCGCCT TTTTCCCATT TATTGTTCTG GTTACAGTTG AGGATGAGCT GAGCTACGTT 
ATTAAAGTAT TCATGAGCCT GCTGTCCCCG ACAGCATTCA GCTATGCAAG CCAATATATT 
GCACGGTATG AAGAACAAGG CGTTGGTCTT CAGTGGGAAA ATATGTACAA ATCCCCTGTT 
CAGGATGACA CCACCTCATT TGGCTGGCTG TGCTGTCTAA TCCTAGCAGA CTCCTTCATT 
TATTTCTTTA TTGCTTGGTA CGTCAGGAAT GTTTTCCCAG GGACATATGG AATGGCAGCT 
CCATGGTATT TTCCCATCCT TCCTTCCTAT TGGAAAGAGC GCTTTGGATG CGCAGAGGTG 
AAGCATGAGA AAAGCAATGG CTTAATGTTT ACTAATATCA TGATGCAGAA CACCAACCCT 
TCTGCCAGTA AGACAAGTCC TGACTGTGCA TTTCCCTCCA ACATTGAACC TGAACCTAAA 
GATCTCCAAG TTGGAGTTGC CCTTCATGGG GTCACAAAGA TCTATGGCTC AAAAACAGCT 
GTTGAGAACC TCAATCTGAA CTTCTACGAA GGGCACATTA CATCACTGTT GGGGCCAAAC 
GGAGCTGGCA AAACCACAAC AATCTCCATG CTGACTGGGC TGTTTGGTGC CACAGCGGGT 
ACCATTTTTG TATACGGAAA AGATATCAAG ACAGACCTGA ATACTGTTCG GAAAAACATG 
GGGGTCTGCA TGCAACATGA CGTCTTGTTC AGTTACCTAA CCACCAAGGA ACACCTTCTC 
CTGTATGGCT CCATCAAAGT TCCTCACTGG ACCAAAACAC AGCTCCATGA GGAGGTTAAA 
AGGACTTTAA AAGACACTGG ACTGTATAGT CATCGCCATA AGAGAGTTGG AACGTTGTCG 
GGAGGAATGA AGAGGAAGTT GTCCATATCC ATAGCTCTCA TCGGTGGCTC CAGGGTAGTG 
ATTTTGGATG AACCATCCAC GGGCGTTGAC CCATGTTCTC GCCGAAGCAT ATGGGATGTC 
ATATCCAAGA ACAAAACTGC AAGAACAATC ATTCTGTCCA CACACCACTT GGATGAGGCC 
GAAGTGCTGA GTGACCGCAT CGCCTTCCTG GAACAGGGTG GGCTCCGGTG CTGTGGATCT 
CCATTTTACC TCAAGGAAGC TTTTGGGGAT GGTTACCACC TCACACTCAC CAAGAAGAAG 
AGTCCAAACC TAGACACAAA TGCAATCTGT GACACAGTGG CAGTGACAGC AATGATCCAG 
TCGCACCTTC CTGAAGCCTA CCTCAAAGAG GATATTGGGG GAGAGCTTGT ATATGTGCTC 
CCTCCATTCA GCACGAAAGT CTCAGGAGCT TACCTGTCCC TCCTGAGAGC ACTGGACAAG 
GGCATGGGTA AACTCAACAT CGGCTGCTAT GGCATTTCAG ACACCACTGT TGAAGAGGTC 
TTCCTGAACT TGACAAAAGA TTCGCAAAAA AGTAGTAATA TGAGTCTGGA GCACTTAACA 
CAGAGGAAAG TTGGGAACCC CAGTGCCAAC GGGACCTCCA CTCCTGACGA CCTGTCTGTG 
AGCAGCAGCA ACTTCACCGA CAGAGACGAC AAAGTCCTGA CAAGAAGCGA GAAGCTGGAG 
GGCTTTGGAC TCTTACTGAA GAAGATAATG GCTATTCTCA TCAAGAGGTT CCACCACACC 
CGCCGGAACT GGAAAGGTCT CATTGCTCAG GTCATTCTCC CCATCGTCTT TGTAGCCACG 
GCCATGGGTC TCGGCACACT GAGAGATTCC AGCAACAGTT ACCCAGAGAT CATGATCTCT 
CCGTCCATTT ACGGCACCTC CGAACAGACA GCCTTCTACG CGAATTTTGA TCCAAGCACC 
AGTGGTCTGG TCTCAGCTCT CTGGAATTTC CCTGGCATTG ACAATGTGTG TTTGAATACT 
AGTGACTTGC AGTGTTTAAA AAAAGATGAT CTGGGAAAGT GGAACACAAG TGGAGAAGCT 
ATCGACAACT TTGGTGTTTG CTCCTGTTCC GACAATGTCC AGGAATGCCC CAAATTCAAC 
TATCATCCAC CTCATAGAAG AACTTACTCT TCCCAAGTTA TTTATAACCT CACTGGAAAA 
CACATGGAAA ATTATCTTAT AACAACTGCA AATCATTTTG TGCAGAAAAG ATATGGAGGT 
TGGAGTTTTG GGATGAAATT GACTAACGAC CTTCGTTTTG ATGTGACAGC TGTCCCTGAC 
AATAGAACTC TTGCTAAGGT GTGGTACGAT CCGGAAGGCT ACCATTCCCT CCCAGCTTAC 
CTCAACAGCC TCAACAACTT CCTCCTGAGG GTTAACATGT CAGAGTACGA TGCTGCCCGA 
CACGGGATCA TCATGTATAG CCACCCTTAT CCAGGGGTAC AAGACCAGGA ACAAGCCACA 
ATCAGCAGTT TAATCGATAT TTTAGTGGCG CTGTCCATCC TGATGGGCTA CTCTGTCACC 
ACTGCCAGCT TTGTCACCTA CATTGTCAGG GAACATCAGA CCAAAGCCAA GCAGTTGCAG 
CACATTTCTG GCATCGGTGT GACGTGCTAC TGGGTGACAA ATTTCATCTA TGACATGGTC 
TTCTATTTGG TTCCTGTAGC ATTTTCAATT GGTGTCATCG CAATTTTCAA GCTTCCTGCC 
TTCTACAGTG GAAACAATCT AGGCGCTGTA TCCCTCCTAC TTTTGCTGTT TGGCTATGCA 
ACATTTTCTT GGATGTACCT GCTGGCTGGC CTCTTCCACG AAACAGGAAT GGCCTTCATC 
ACTTATGTGT GTGTCAACCT GTTCTTTGGT ATCAATTCCA TCGTTTCCCT GTCGGTGGTA 
TACTTCCTTT CCAAGGAAAA GCCTAATGAC CCGACGCTAG AACTTATTTC TGAAACTCTC 
AAGCGGATTT TCCTGATCTT CCCCCAATTC TGTTTTGGCT ACGGTTTGAT TGAACTTTCT 
CAGCAACAGG CAGTCTTGGA TTTCTTAAAA GCCTACGGTG TGGAATATCC AAGCGAGACC 
TTTGAGATGG ATAAGCTGGG GGCAATGTTT GTGGCCTTGG TTTCTCAGGG CACCATGTTT 
TTCTTGTTGC GACTCCTCAT CAATGAGTGG CTGATAAAGA AGCTCAGGCT CTTCTTCAGG 
AAATTTACAT CTTCGCCTAT CATGGAGACA GTAGATGAAG ATGAAGATGT GCGGGCTGAG 
AGATTTCGAG TTGAGAGTGG TGCAGCTGAG TTTGACCTGG TCCAGCTCCA TCGTCTCACA 
AAGACCTACC AGCTGATCCA CAAGAAGATT ATAGCTGTCA ACAACATCAG CCTGGGGATA 
CCTGCTGGAG AGTGTTTTGG CCTCCTTGGT GTGAACGGAG CAGGGAAAAC CACTATATTT 
AAGATGCTGA CTGGAGACAT AATTCCTTCC AGTGGAAACA TTCTGATCAG AAACAAGAGC 
GGATCCCTGG GACATGTGGA TTCTCACAGC TCTTTGGTTG GCTACTGCCC TCAGGAGGAC 
GCTTTAGATG ACCTAGTAAC TGTGGAAGAG CACTTGTATT TCTATGCCAG AGTGCATGGG 
ATTCCAGAGA AGGACATCAA AGACACTGTT CATAAACTCC TTAGGAGACT TCACTTGATG 
GCCTACAAGG ACAGATCTAC CTCCATGTGC AGTTACGGCA CAAAAAGGAA GCTGTCCACT 
GCCCTGGCCT TGATAGGGAA ACCGTCCATC CTCCTGCTGG ATGAGCCAAG CTCTGGGATG 
GATCCCAAGT CAAAACGACA CCTCTGGAGG ATCATTTCAG AAGAGGTGCA GAACAAATGC 
TCTGTCATCC TCACATCTCA CAGCATGGAA GAATGTGAAG CTCTTTGTAC CCGGCTGGCC 
ATTATGGTGA ACGGAAGGTT CCAGTGCATT GGGTCTCTGC AACACATAAA AAGCAGGTTT 
GGACGTGGAT TTACTGTCAA GGTTCACTTG AAAAATAATA AAGTGAGCAT GGAAACCCTC 
ACGAAGTTTA TGCAGCTACA CTTTCCAAAA ACATACTTAA AAGATCAGCA CCTGAGCATG 
CTGGAGTACC ACGTGCCAGT CACAGCAGGA GGGGTCGCAA ACATCTTTGA CCTTCTGGAA 
ACCAACAAGA CTGCTTTAAA TATCACAAAT TTCCTCGTGA GCCAGACCAC TTTGGAGGAG 
GTTTTCATCA ACTTTGCCAA AGACCAAAAA TCCTACGAAA ATGTTGATAC CAGTAGCCAA 
GGTTCCACCA TAAGTGTAGA CTCACAGGAA GATCAACTAG ATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_780419.2
CDS	329..8116
Translation	MASQFHQLRILVWKNWLGVKRQPLWTLVLILWPVIIFIILAITRTKFPPTAKPTCYLAPRNLPSAGFFPFLQTLLCDTDSKCKDTPYGPRDLLRRKGIDGPLFKESEILKKPSNPKRDSNLSLRSTQVPERSHTSLATVPPRPSYDLEGTGTENFNGSQLLTRILGLEKLLKQNSTPEDIRRELCESYPGYTADYAFSWVTLGKNVFNKFCLSNMTLLESSLQELKYQVSQMSSDPDNQKRVFRGLVQVLSFFSQVQQQREVWQLLSSLPDVFQNGTSLSSLFGVLQKANRVLLVVQKVYPRVQTDEGFSTLQKSVKHLLNTLDSPMQGDNSTHAWSDDDEQTLSPSSLAAQLLILENFEDAILNISSNSPYSPYLACVRNMTDNLAKGSPDNLKLLQSTIHFRKSFLQNGSSEDSFPPFLEILKSKLSQLRNLTELLCESETFSSIKKSCQFSNMSFERLCEDHAFHVQLIEAAELGTDLTTGLLYHDNIISAKLRGLLTGDPSKINLNVDWLLEQALQMNYLENITRLIPTVEAMLHVNTSADASEKPGQLREMFKNIDLLKEDLRAIGMSNTSIDKLLAIPIPDNRAEIISRVFWLHSCDTNVTNPKLEDAMKEFCKLPLPERSHQSYLIGLTLLHYLDIYNFTYKVFFPRKDQKPMERMMELFIKLREILNQLASGTHPLLDKMRSLRQMHLPRSVPLTQAMYRNTRMNSPAGSFSTISQALCSQGITTEYLTAMLPSSQKPKGNHTKDFLTYKLTKEEIASKYGIPLNATPFCFSLYKDIINMPAGPVIWAFLKPMLLGKILYSPYNPTTKAIMEKSNVTLRQLAELREKSQEWMDKSPIFMNSFHLLNQTIPMLQNTLRNPFVQVFVKFSVGLDAVELLKQIDDLDVLRLKLVNNIDIIDQLNTLSSLTVNISSCVLYDRIQASDTVEEMETVAEQLYKSNELFGSVIFKLPSNGSLHRGFDPEKVSLPPIVRYTIRMSLKTAQTTRSIRTKIWAPGPHNSPSHNQIYGRAFIYLQDSIERAIIELQTGRNSQEVAVQVQAVPYPCFMKDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEKDLRLHEYMKMMGVNSCSHFFAWLIESIGFLLVTIAILIVILKFGNILPKTNGFILFLYFSDYSFSVIAMSYLISVFFNNTNIAALIGSLIYVIAFFPFIVLVTVEDELSYVIKVFMSLLSPTAFSYASQYIARYEEQGVGLQWENMYKSPVQDDTTSFGWLCCLILADSFIYFFIAWYVRNVFPGTYGMAAPWYFPILPSYWKERFGCAEVKHEKSNGLMFTNIMMQNTNPSASKTSPDCAFPSNIEPEPKDLQVGVALHGVTKIYGSKTAVENLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGATAGTIFVYGKDIKTDLNTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKTQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVLSDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKKSPNLDTNAICDTVAVTAMIQSHLPEAYLKEDIGGELVYVLPPFSTKVSGAYLSLLRALDKGMGKLNIGCYGISDTTVEEVFLNLTKDSQKSSNMSLEHLTQRKVGNPSANGTSTPDDLSVSSSNFTDRDDKVLTRSEKLEGFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILPIVFVATAMGLGTLRDSSNSYPEIMISPSIYGTSEQTAFYANFDPSTSGLVSALWNFPGIDNVCLNTSDLQCLKKDDLGKWNTSGEAIDNFGVCSCSDNVQECPKFNYHPPHRRTYSSQVIYNLTGKHMENYLITTANHFVQKRYGGWSFGMKLTNDLRFDVTAVPDNRTLAKVWYDPEGYHSLPAYLNSLNNFLLRVNMSEYDAARHGIIMYSHPYPGVQDQEQATISSLIDILVALSILMGYSVTTASFVTYIVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVAFSIGVIAIFKLPAFYSGNNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSIVSLSVVYFLSKEKPNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQAVLDFLKAYGVEYPSETFEMDKLGAMFVALVSQGTMFFLLRLLINEWLIKKLRLFFRKFTSSPIMETVDEDEDVRAERFRVESGAAEFDLVQLHRLTKTYQLIHKKIIAVNNISLGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKSGSLGHVDSHSSLVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKDTVHKLLRRLHLMAYKDRSTSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWRIISEEVQNKCSVILTSHSMEECEALCTRLAIMVNGRFQCIGSLQHIKSRFGRGFTVKVHLKNNKVSMETLTKFMQLHFPKTYLKDQHLSMLEYHVPVTAGGVANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKDQKSYENVDTSSQGSTISVDSQEDQLDS

Target ORF information:

RefSeq Version	NM_175210.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family A (ABC1), member 12 (Abca12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175210.3

ORF Insert Sequence:

ATGGCTTCCC AGTTTCATCA GCTTCGGATC CTGGTGTGGA AAAATTGGCT AGGTGTCAAA 
AGGCAGCCGC TTTGGACACT TGTCTTGATC TTATGGCCAG TCATTATTTT CATAATTCTG 
GCTATTACCC GGACAAAATT CCCGCCAACA GCAAAACCAA CTTGTTACCT CGCACCTCGA 
AACCTTCCCA GTGCTGGATT CTTCCCATTC CTACAAACCC TGCTCTGTGA CACAGACTCT 
AAATGTAAAG ACACGCCCTA TGGACCACGA GATCTGCTCC GCAGGAAGGG GATTGATGGA 
CCGCTATTTA AAGAAAGCGA AATTCTGAAA AAGCCGTCCA ACCCGAAGAG GGACAGCAAT 
TTATCACTCC GGAGCACCCA AGTTCCAGAA AGAAGTCACA CATCATTGGC CACAGTACCT 
CCAAGACCAA GCTATGATTT GGAAGGAACA GGCACAGAAA ATTTCAATGG TAGCCAATTG 
CTTACACGCA TCCTTGGTTT GGAAAAGCTG CTGAAGCAAA ATTCAACTCC AGAAGACATA 
CGAAGAGAGC TGTGTGAGAG CTACCCTGGG TACACTGCGG ACTATGCCTT CTCTTGGGTC 
ACCCTAGGAA AAAACGTTTT TAACAAATTT TGCCTTTCGA ACATGACACT TTTAGAGTCT 
TCACTCCAGG AACTAAAATA TCAAGTCTCT CAGATGTCAA GTGACCCCGA CAATCAGAAG 
AGGGTGTTCC GGGGACTTGT CCAGGTGCTG TCCTTTTTCT CTCAAGTGCA GCAGCAAAGA 
GAAGTGTGGC AACTTCTGTC GAGCTTACCA GATGTGTTTC AGAATGGCAC CTCATTGAGC 
AGTCTATTTG GTGTTCTTCA AAAGGCAAAC AGGGTGCTGC TGGTAGTGCA GAAGGTTTAC 
CCACGTGTTC AAACTGATGA AGGATTCAGC ACCCTCCAGA AGTCTGTTAA ACATCTGCTG 
AACACTCTGG ACTCCCCAAT GCAAGGTGAC AATTCAACGC ACGCATGGAG TGATGATGAT 
GAGCAGACAC TGTCCCCGAG CAGTCTGGCT GCACAGCTCC TGATCCTGGA AAACTTTGAA 
GATGCCATCT TGAACATATC ATCAAATAGT CCATATTCTC CTTATTTGGC GTGTGTAAGG 
AACATGACTG ACAACTTGGC TAAGGGATCA CCAGACAATC TAAAACTTCT GCAGTCCACA 
ATTCACTTCA GAAAATCTTT CCTTCAAAAT GGCTCCTCCG AGGACAGCTT CCCTCCATTT 
CTTGAGATCC TGAAATCCAA GCTGTCTCAA CTTCGAAATT TGACGGAACT TCTCTGCGAA 
TCAGAGACTT TCAGTTCGAT CAAGAAGTCT TGCCAGTTCT CTAACATGAG CTTCGAGAGG 
CTGTGTGAAG ACCATGCCTT TCACGTGCAA CTGATTGAAG CGGCAGAGCT GGGCACTGAC 
CTCACCACTG GCTTACTGTA CCATGACAAT ATAATATCTG CAAAGCTGAG GGGTTTGCTC 
ACTGGAGATC CCAGCAAAAT TAATCTCAAT GTGGACTGGC TCCTGGAACA GGCATTGCAA 
ATGAATTACT TGGAGAATAT CACACGGCTC ATACCAACCG TAGAGGCCAT GCTGCATGTC 
AACACCAGTG CAGACGCTTC TGAGAAGCCA GGTCAATTAA GAGAAATGTT TAAAAACATA 
GATTTGCTGA AAGAAGATCT GAGGGCGATA GGGATGTCCA ACACAAGTAT CGACAAGCTG 
TTGGCCATTC CCATTCCAGA CAATAGAGCC GAGATAATTT CTCGTGTATT CTGGTTGCAC 
TCATGTGATA CCAACGTCAC CAACCCCAAA CTGGAAGATG CCATGAAGGA GTTCTGCAAG 
CTGCCTCTTC CAGAGAGATC ACATCAGTCC TACCTCATCG GACTCACCCT TCTGCACTAC 
TTAGACATTT ACAATTTCAC ATACAAGGTG TTTTTCCCAA GGAAGGATCA AAAGCCAATG 
GAAAGGATGA TGGAGCTTTT CATAAAGCTG AGAGAGATTC TCAATCAGTT GGCTTCCGGC 
ACACATCCAC TGCTGGACAA AATGAGATCC CTGAGACAAA TGCACCTGCC CAGGAGTGTT 
CCATTAACAC AGGCCATGTA CAGAAACACT CGAATGAACT CGCCAGCAGG ATCGTTCAGT 
ACTATCTCCC AGGCTCTGTG CTCCCAGGGG ATCACCACCG AGTACTTAAC TGCTATGCTG 
CCTTCTTCCC AGAAGCCAAA AGGCAACCAC ACCAAGGATT TTCTCACTTA TAAATTAACT 
AAAGAAGAAA TTGCTTCAAA ATACGGGATT CCTTTAAATG CTACACCATT TTGCTTCTCC 
CTTTACAAAG ACATCATTAA CATGCCTGCT GGGCCTGTGA TTTGGGCCTT CTTGAAACCC 
ATGTTGTTGG GAAAGATTTT ATATTCACCA TATAACCCAA CTACAAAGGC CATTATGGAA 
AAGTCCAATG TAACTCTAAG ACAGCTGGCG GAATTAAGAG AAAAATCTCA GGAGTGGATG 
GATAAGTCAC CAATTTTCAT GAATTCCTTC CACCTGCTAA ACCAGACGAT CCCAATGCTC 
CAGAATACTC TACGGAACCC CTTTGTGCAA GTTTTTGTGA AGTTCTCCGT GGGACTCGAT 
GCTGTCGAAC TCCTGAAGCA GATAGACGAC CTTGATGTTC TCAGGCTGAA ATTAGTGAAC 
AACATTGACA TCATTGATCA GCTCAACACA CTGTCTTCCC TGACTGTAAA TATTTCCTCC 
TGTGTTCTTT ACGACCGTAT TCAGGCGTCA GACACTGTAG AGGAGATGGA GACGGTGGCC 
GAACAACTCT ACAAGAGCAA CGAGCTCTTT GGAAGTGTCA TTTTTAAGCT TCCATCTAAC 
GGAAGTTTGC ACAGAGGGTT TGACCCTGAA AAAGTGTCTC TTCCTCCTAT CGTAAGATAT 
ACCATCCGCA TGAGTCTGAA GACGGCACAG ACCACAAGGA GCATAAGAAC AAAGATCTGG 
GCCCCAGGGC CACACAACTC TCCATCCCAT AACCAGATCT ATGGCCGGGC TTTCATTTAT 
CTGCAGGATA GCATTGAGAG AGCAATTATT GAGTTACAAA CAGGAAGGAA CTCACAGGAA 
GTCGCCGTCC AGGTTCAAGC GGTTCCTTAT CCCTGCTTCA TGAAGGACAA TTTCCTCACC 
AGTGTCTCCT ATTCCCTCCC GATTGTGCTT ATGGTCGCCT GGGTTGTATT TATAGCTGCC 
TTTGTTAAAA AGCTAGTCTA CGAGAAGGAC CTTCGGCTCC ATGAGTACAT GAAGATGATG 
GGTGTCAACT CCTGCAGCCA TTTCTTTGCC TGGCTTATAG AGAGTATTGG GTTCTTGCTG 
GTCACCATTG CAATCCTCAT CGTTATCCTC AAGTTTGGCA ATATTCTTCC CAAGACAAAC 
GGCTTCATTT TGTTCCTGTA CTTCTCAGAC TACAGCTTCT CAGTGATTGC CATGAGCTAT 
CTCATCAGTG TCTTCTTCAA CAACACCAAC ATTGCAGCTC TGATTGGAAG CCTCATCTAT 
GTCATCGCCT TTTTCCCATT TATTGTTCTG GTTACAGTTG AGGATGAGCT GAGCTACGTT 
ATTAAAGTAT TCATGAGCCT GCTGTCCCCG ACAGCATTCA GCTATGCAAG CCAATATATT 
GCACGGTATG AAGAACAAGG CGTTGGTCTT CAGTGGGAAA ATATGTACAA ATCCCCTGTT 
CAGGATGACA CCACCTCATT TGGCTGGCTG TGCTGTCTAA TCCTAGCAGA CTCCTTCATT 
TATTTCTTTA TTGCTTGGTA CGTCAGGAAT GTTTTCCCAG GGACATATGG AATGGCAGCT 
CCATGGTATT TTCCCATCCT TCCTTCCTAT TGGAAAGAGC GCTTTGGATG CGCAGAGGTG 
AAGCATGAGA AAAGCAATGG CTTAATGTTT ACTAATATCA TGATGCAGAA CACCAACCCT 
TCTGCCAGTA AGACAAGTCC TGACTGTGCA TTTCCCTCCA ACATTGAACC TGAACCTAAA 
GATCTCCAAG TTGGAGTTGC CCTTCATGGG GTCACAAAGA TCTATGGCTC AAAAACAGCT 
GTTGAGAACC TCAATCTGAA CTTCTACGAA GGGCACATTA CATCACTGTT GGGGCCAAAC 
GGAGCTGGCA AAACCACAAC AATCTCCATG CTGACTGGGC TGTTTGGTGC CACAGCGGGT 
ACCATTTTTG TATACGGAAA AGATATCAAG ACAGACCTGA ATACTGTTCG GAAAAACATG 
GGGGTCTGCA TGCAACATGA CGTCTTGTTC AGTTACCTAA CCACCAAGGA ACACCTTCTC 
CTGTATGGCT CCATCAAAGT TCCTCACTGG ACCAAAACAC AGCTCCATGA GGAGGTTAAA 
AGGACTTTAA AAGACACTGG ACTGTATAGT CATCGCCATA AGAGAGTTGG AACGTTGTCG 
GGAGGAATGA AGAGGAAGTT GTCCATATCC ATAGCTCTCA TCGGTGGCTC CAGGGTAGTG 
ATTTTGGATG AACCATCCAC GGGCGTTGAC CCATGTTCTC GCCGAAGCAT ATGGGATGTC 
ATATCCAAGA ACAAAACTGC AAGAACAATC ATTCTGTCCA CACACCACTT GGATGAGGCC 
GAAGTGCTGA GTGACCGCAT CGCCTTCCTG GAACAGGGTG GGCTCCGGTG CTGTGGATCT 
CCATTTTACC TCAAGGAAGC TTTTGGGGAT GGTTACCACC TCACACTCAC CAAGAAGAAG 
AGTCCAAACC TAGACACAAA TGCAATCTGT GACACAGTGG CAGTGACAGC AATGATCCAG 
TCGCACCTTC CTGAAGCCTA CCTCAAAGAG GATATTGGGG GAGAGCTTGT ATATGTGCTC 
CCTCCATTCA GCACGAAAGT CTCAGGAGCT TACCTGTCCC TCCTGAGAGC ACTGGACAAG 
GGCATGGGTA AACTCAACAT CGGCTGCTAT GGCATTTCAG ACACCACTGT TGAAGAGGTC 
TTCCTGAACT TGACAAAAGA TTCGCAAAAA AGTAGTAATA TGAGTCTGGA GCACTTAACA 
CAGAGGAAAG TTGGGAACCC CAGTGCCAAC GGGACCTCCA CTCCTGACGA CCTGTCTGTG 
AGCAGCAGCA ACTTCACCGA CAGAGACGAC AAAGTCCTGA CAAGAAGCGA GAAGCTGGAG 
GGCTTTGGAC TCTTACTGAA GAAGATAATG GCTATTCTCA TCAAGAGGTT CCACCACACC 
CGCCGGAACT GGAAAGGTCT CATTGCTCAG GTCATTCTCC CCATCGTCTT TGTAGCCACG 
GCCATGGGTC TCGGCACACT GAGAGATTCC AGCAACAGTT ACCCAGAGAT CATGATCTCT 
CCGTCCATTT ACGGCACCTC CGAACAGACA GCCTTCTACG CGAATTTTGA TCCAAGCACC 
AGTGGTCTGG TCTCAGCTCT CTGGAATTTC CCTGGCATTG ACAATGTGTG TTTGAATACT 
AGTGACTTGC AGTGTTTAAA AAAAGATGAT CTGGGAAAGT GGAACACAAG TGGAGAAGCT 
ATCGACAACT TTGGTGTTTG CTCCTGTTCC GACAATGTCC AGGAATGCCC CAAATTCAAC 
TATCATCCAC CTCATAGAAG AACTTACTCT TCCCAAGTTA TTTATAACCT CACTGGAAAA 
CACATGGAAA ATTATCTTAT AACAACTGCA AATCATTTTG TGCAGAAAAG ATATGGAGGT 
TGGAGTTTTG GGATGAAATT GACTAACGAC CTTCGTTTTG ATGTGACAGC TGTCCCTGAC 
AATAGAACTC TTGCTAAGGT GTGGTACGAT CCGGAAGGCT ACCATTCCCT CCCAGCTTAC 
CTCAACAGCC TCAACAACTT CCTCCTGAGG GTTAACATGT CAGAGTACGA TGCTGCCCGA 
CACGGGATCA TCATGTATAG CCACCCTTAT CCAGGGGTAC AAGACCAGGA ACAAGCCACA 
ATCAGCAGTT TAATCGATAT TTTAGTGGCG CTGTCCATCC TGATGGGCTA CTCTGTCACC 
ACTGCCAGCT TTGTCACCTA CATTGTCAGG GAACATCAGA CCAAAGCCAA GCAGTTGCAG 
CACATTTCTG GCATCGGTGT GACGTGCTAC TGGGTGACAA ATTTCATCTA TGACATGGTC 
TTCTATTTGG TTCCTGTAGC ATTTTCAATT GGTGTCATCG CAATTTTCAA GCTTCCTGCC 
TTCTACAGTG GAAACAATCT AGGCGCTGTA TCCCTCCTAC TTTTGCTGTT TGGCTATGCA 
ACATTTTCTT GGATGTACCT GCTGGCTGGC CTCTTCCACG AAACAGGAAT GGCCTTCATC 
ACTTATGTGT GTGTCAACCT GTTCTTTGGT ATCAATTCCA TCGTTTCCCT GTCGGTGGTA 
TACTTCCTTT CCAAGGAAAA GCCTAATGAC CCGACGCTAG AACTTATTTC TGAAACTCTC 
AAGCGGATTT TCCTGATCTT CCCCCAATTC TGTTTTGGCT ACGGTTTGAT TGAACTTTCT 
CAGCAACAGG CAGTCTTGGA TTTCTTAAAA GCCTACGGTG TGGAATATCC AAGCGAGACC 
TTTGAGATGG ATAAGCTGGG GGCAATGTTT GTGGCCTTGG TTTCTCAGGG CACCATGTTT 
TTCTTGTTGC GACTCCTCAT CAATGAGTGG CTGATAAAGA AGCTCAGGCT CTTCTTCAGG 
AAATTTACAT CTTCGCCTAT CATGGAGACA GTAGATGAAG ATGAAGATGT GCGGGCTGAG 
AGATTTCGAG TTGAGAGTGG TGCAGCTGAG TTTGACCTGG TCCAGCTCCA TCGTCTCACA 
AAGACCTACC AGCTGATCCA CAAGAAGATT ATAGCTGTCA ACAACATCAG CCTGGGGATA 
CCTGCTGGAG AGTGTTTTGG CCTCCTTGGT GTGAACGGAG CAGGGAAAAC CACTATATTT 
AAGATGCTGA CTGGAGACAT AATTCCTTCC AGTGGAAACA TTCTGATCAG AAACAAGAGC 
GGATCCCTGG GACATGTGGA TTCTCACAGC TCTTTGGTTG GCTACTGCCC TCAGGAGGAC 
GCTTTAGATG ACCTAGTAAC TGTGGAAGAG CACTTGTATT TCTATGCCAG AGTGCATGGG 
ATTCCAGAGA AGGACATCAA AGACACTGTT CATAAACTCC TTAGGAGACT TCACTTGATG 
GCCTACAAGG ACAGATCTAC CTCCATGTGC AGTTACGGCA CAAAAAGGAA GCTGTCCACT 
GCCCTGGCCT TGATAGGGAA ACCGTCCATC CTCCTGCTGG ATGAGCCAAG CTCTGGGATG 
GATCCCAAGT CAAAACGACA CCTCTGGAGG ATCATTTCAG AAGAGGTGCA GAACAAATGC 
TCTGTCATCC TCACATCTCA CAGCATGGAA GAATGTGAAG CTCTTTGTAC CCGGCTGGCC 
ATTATGGTGA ACGGAAGGTT CCAGTGCATT GGGTCTCTGC AACACATAAA AAGCAGGTTT 
GGACGTGGAT TTACTGTCAA GGTTCACTTG AAAAATAATA AAGTGAGCAT GGAAACCCTC 
ACGAAGTTTA TGCAGCTACA CTTTCCAAAA ACATACTTAA AAGATCAGCA CCTGAGCATG 
CTGGAGTACC ACGTGCCAGT CACAGCAGGA GGGGTCGCAA ACATCTTTGA CCTTCTGGAA 
ACCAACAAGA CTGCTTTAAA TATCACAAAT TTCCTCGTGA GCCAGACCAC TTTGGAGGAG 
GTTTTCATCA ACTTTGCCAA AGACCAAAAA TCCTACGAAA ATGTTGATAC CAGTAGCCAA 
GGTTCCACCA TAAGTGTAGA CTCACAGGAA GATCAACTAG ATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Human molecular genetics26(10)1787-1800(2017 05)
Pichery M,Huchenq A,Sandhoff R,Severino-Freire M,Zaafouri S,Opálka L,Levade T,Soldan V,Bertrand-Michel J,Lhuillier E,Serre G,Maruani A,Mazereeuw-Hautier J,Jonca N

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
PloS one11(8)e0161465(2016)
Zhang L,Ferreyros M,Feng W,Hupe M,Crumrine DA,Chen J,Elias PM,Holleran WM,Niswander L,Hohl D,Williams T,Torchia EC,Roop DR

Variant mapping and mutation discovery in inbred mice using next-generation sequencing.
BMC genomics16913(2015 Nov)
Gallego-Llamas J,Timms AE,Geister KA,Lindsay A,Beier DR

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis.
Human molecular genetics24(2)436-49(2015 Jan)
Cottle DL,Ursino GM,Ip SC,Jones LK,Ditommaso T,Hacking DF,Mangan NE,Mellett NA,Henley KJ,Sviridov D,Nold-Petry CA,Nold MF,Meikle PJ,Kile BT,Smyth IM

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.
Journal of lipid research55(3)493-503(2014 Mar)
Haller JF,Cavallaro P,Hernandez NJ,Dolat L,Soscia SJ,Welti R,Grabowski GA,Fitzgerald ML,Freeman MW

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Abca12 cDNA ORF clone, Mus musculus(house mouse)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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