| Gene Symbol | Bdh1 |
| Entrez Gene ID | 71911 |
| Full Name | 3-hydroxybutyrate dehydrogenase, type 1 |
| Synonyms | 2310032J20Rik,AI327223,Bdh |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Bdh1 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Bdh1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bdh1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu21399 Clone ID Related Accession (Same CDS sequence) NM_175177.4 , NM_001122683.1 Accession Version NM_175177.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1032bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577203200000 Organism Mus musculus(house mouse) Product D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY148101.1, AK145711.1, AK146962.1, AA789526.1 and BE979314.1. On Mar 15, 2008 this sequence version replaced NM_175177.3. ##Evidence-Data-START## Transcript exon combination :: BC043683.1, AI196888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCTAGCTG CCCGTCTCTC CAGACCCCTG TCACAGCTCC CAGGAAAAGC CCTAAGTGTC
CGTGACAGAG AAAATGGGAC AAGACACACA CTGTTGTTTT ATCCAGCATC CTTCAGCCCT
GACACCCGTC GGACCTACGC CAGTCAGGCA GATGCGGCTA GTGGCAAAGC TATCCTGATC
ACAGGCTGTG ACTCTGGATT TGGGTTCTCA CTGGCCAAGC ATCTGCACTC AAAAGGCTTC
CTTGTATTTG CTGGCTGTTT GATGAAGGAC AAAGGTGATG CTGGGGTCAA GGAACTGGAC
AGCTTGAAGA GTGACCGACT GAGAACCATC CAGCTCAATG TCTGCAACAG TGAAGAGGTG
GAGAAGGCGG TGGAGACGAT CCGCTCCGGC CTGAAAGATC CTGAGAAGGG AATGTGGGGC
CTGGTTAACA ACGCAGGCAT CTCAACGTTT GGGGAGGTGG AGTTCACCAG CATGGAGACA
TATAAGGAGG TGGCTGAAGT GAACCTCTGG GGAACCGTGC GCACCACAAA ATCCTTCCTT
CCCCTTCTCC GAAGAGCCAA AGGTCGCGTC GTTAACATCA GCAGCATGCT GGGCCGCATG
GCCAACCCCG CCCGCTCGCC ATACTGCATC ACCAAGTTTG GGATCGAGGC TTTCTCGGAC
TGCCTGCGCT ATGAGATGCA CCCTCTGGGT GTCAAGGTCA GTGTGGTGGA ACCTGGCAAC
TTCATAGCGG CCACCAGTCT CTACAGCCCC GAGCGCATCC AGGCCATCGC CAAGAAGATG
TGGGATGACC TGCCTGAGGT CGTCCGCAAG GACTATGGCA GGAAGTACTT CGATGAAAAG
ATTGCCAAGA TGGAAACCTA CTGCAACAGC GGTTCCACAG ATACTTCCTC TGTCATCAAC
GCTGTCACAC ACGCCTTGAC CGCCGCCACC CCGTATACCC GCTACCATCC CATGGACTAC
TACTGGTGGC TTCGGATGCA GATCATGACC CATTTTCCTG GAGCCATCTC TGACAAGATC
TACATACACT GAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_780386.3 CDS 260..1291 Translation 
Target ORF information:
RefSeq Version NM_175177.4 Organism Mus musculus(house mouse) Definition Mus musculus 3-hydroxybutyrate dehydrogenase, type 1 (Bdh1), transcript variant 1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_175177.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCTAGCTG CCCGTCTCTC CAGACCCCTG TCACAGCTCC CAGGAAAAGC CCTAAGTGTC
CGTGACAGAG AAAATGGGAC AAGACACACA CTGTTGTTTT ATCCAGCATC CTTCAGCCCT
GACACCCGTC GGACCTACGC CAGTCAGGCA GATGCGGCTA GTGGCAAAGC TATCCTGATC
ACAGGCTGTG ACTCTGGATT TGGGTTCTCA CTGGCCAAGC ATCTGCACTC AAAAGGCTTC
CTTGTATTTG CTGGCTGTTT GATGAAGGAC AAAGGTGATG CTGGGGTCAA GGAACTGGAC
AGCTTGAAGA GTGACCGACT GAGAACCATC CAGCTCAATG TCTGCAACAG TGAAGAGGTG
GAGAAGGCGG TGGAGACGAT CCGCTCCGGC CTGAAAGATC CTGAGAAGGG AATGTGGGGC
CTGGTTAACA ACGCAGGCAT CTCAACGTTT GGGGAGGTGG AGTTCACCAG CATGGAGACA
TATAAGGAGG TGGCTGAAGT GAACCTCTGG GGAACCGTGC GCACCACAAA ATCCTTCCTT
CCCCTTCTCC GAAGAGCCAA AGGTCGCGTC GTTAACATCA GCAGCATGCT GGGCCGCATG
GCCAACCCCG CCCGCTCGCC ATACTGCATC ACCAAGTTTG GGATCGAGGC TTTCTCGGAC
TGCCTGCGCT ATGAGATGCA CCCTCTGGGT GTCAAGGTCA GTGTGGTGGA ACCTGGCAAC
TTCATAGCGG CCACCAGTCT CTACAGCCCC GAGCGCATCC AGGCCATCGC CAAGAAGATG
TGGGATGACC TGCCTGAGGT CGTCCGCAAG GACTATGGCA GGAAGTACTT CGATGAAAAG
ATTGCCAAGA TGGAAACCTA CTGCAACAGC GGTTCCACAG ATACTTCCTC TGTCATCAAC
GCTGTCACAC ACGCCTTGAC CGCCGCCACC CCGTATACCC GCTACCATCC CATGGACTAC
TACTGGTGGC TTCGGATGCA GATCATGACC CATTTTCCTG GAGCCATCTC TGACAAGATC
TACATACACT GAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OMu21399 Clone ID Related Accession (Same CDS sequence) NM_175177.4 , NM_001122683.1 Accession Version NM_001122683.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1032bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577289600000 Organism Mus musculus(house mouse) Product D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK145711.1, AK146962.1, AA789526.1 and BE979314.1. ##Evidence-Data-START## Transcript exon combination :: AK146321.1, AK145711.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCTAGCTG CCCGTCTCTC CAGACCCCTG TCACAGCTCC CAGGAAAAGC CCTAAGTGTC
CGTGACAGAG AAAATGGGAC AAGACACACA CTGTTGTTTT ATCCAGCATC CTTCAGCCCT
GACACCCGTC GGACCTACGC CAGTCAGGCA GATGCGGCTA GTGGCAAAGC TATCCTGATC
ACAGGCTGTG ACTCTGGATT TGGGTTCTCA CTGGCCAAGC ATCTGCACTC AAAAGGCTTC
CTTGTATTTG CTGGCTGTTT GATGAAGGAC AAAGGTGATG CTGGGGTCAA GGAACTGGAC
AGCTTGAAGA GTGACCGACT GAGAACCATC CAGCTCAATG TCTGCAACAG TGAAGAGGTG
GAGAAGGCGG TGGAGACGAT CCGCTCCGGC CTGAAAGATC CTGAGAAGGG AATGTGGGGC
CTGGTTAACA ACGCAGGCAT CTCAACGTTT GGGGAGGTGG AGTTCACCAG CATGGAGACA
TATAAGGAGG TGGCTGAAGT GAACCTCTGG GGAACCGTGC GCACCACAAA ATCCTTCCTT
CCCCTTCTCC GAAGAGCCAA AGGTCGCGTC GTTAACATCA GCAGCATGCT GGGCCGCATG
GCCAACCCCG CCCGCTCGCC ATACTGCATC ACCAAGTTTG GGATCGAGGC TTTCTCGGAC
TGCCTGCGCT ATGAGATGCA CCCTCTGGGT GTCAAGGTCA GTGTGGTGGA ACCTGGCAAC
TTCATAGCGG CCACCAGTCT CTACAGCCCC GAGCGCATCC AGGCCATCGC CAAGAAGATG
TGGGATGACC TGCCTGAGGT CGTCCGCAAG GACTATGGCA GGAAGTACTT CGATGAAAAG
ATTGCCAAGA TGGAAACCTA CTGCAACAGC GGTTCCACAG ATACTTCCTC TGTCATCAAC
GCTGTCACAC ACGCCTTGAC CGCCGCCACC CCGTATACCC GCTACCATCC CATGGACTAC
TACTGGTGGC TTCGGATGCA GATCATGACC CATTTTCCTG GAGCCATCTC TGACAAGATC
TACATACACT GAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001116155.1 CDS 279..1310 Translation
Target ORF information:
RefSeq Version NM_001122683.1 Organism Mus musculus(house mouse) Definition Mus musculus 3-hydroxybutyrate dehydrogenase, type 1 (Bdh1), transcript variant 2, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_001122683.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021ATGCTAGCTG CCCGTCTCTC CAGACCCCTG TCACAGCTCC CAGGAAAAGC CCTAAGTGTC
CGTGACAGAG AAAATGGGAC AAGACACACA CTGTTGTTTT ATCCAGCATC CTTCAGCCCT
GACACCCGTC GGACCTACGC CAGTCAGGCA GATGCGGCTA GTGGCAAAGC TATCCTGATC
ACAGGCTGTG ACTCTGGATT TGGGTTCTCA CTGGCCAAGC ATCTGCACTC AAAAGGCTTC
CTTGTATTTG CTGGCTGTTT GATGAAGGAC AAAGGTGATG CTGGGGTCAA GGAACTGGAC
AGCTTGAAGA GTGACCGACT GAGAACCATC CAGCTCAATG TCTGCAACAG TGAAGAGGTG
GAGAAGGCGG TGGAGACGAT CCGCTCCGGC CTGAAAGATC CTGAGAAGGG AATGTGGGGC
CTGGTTAACA ACGCAGGCAT CTCAACGTTT GGGGAGGTGG AGTTCACCAG CATGGAGACA
TATAAGGAGG TGGCTGAAGT GAACCTCTGG GGAACCGTGC GCACCACAAA ATCCTTCCTT
CCCCTTCTCC GAAGAGCCAA AGGTCGCGTC GTTAACATCA GCAGCATGCT GGGCCGCATG
GCCAACCCCG CCCGCTCGCC ATACTGCATC ACCAAGTTTG GGATCGAGGC TTTCTCGGAC
TGCCTGCGCT ATGAGATGCA CCCTCTGGGT GTCAAGGTCA GTGTGGTGGA ACCTGGCAAC
TTCATAGCGG CCACCAGTCT CTACAGCCCC GAGCGCATCC AGGCCATCGC CAAGAAGATG
TGGGATGACC TGCCTGAGGT CGTCCGCAAG GACTATGGCA GGAAGTACTT CGATGAAAAG
ATTGCCAAGA TGGAAACCTA CTGCAACAGC GGTTCCACAG ATACTTCCTC TGTCATCAAC
GCTGTCACAC ACGCCTTGAC CGCCGCCACC CCGTATACCC GCTACCATCC CATGGACTAC
TACTGGTGGC TTCGGATGCA GATCATGACC CATTTTCCTG GAGCCATCTC TGACAAGATC
TACATACACT GAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
JCI insight4(4)(2019 02)
Horton JL,Davidson MT,Kurishima C,Vega RB,Powers JC,Matsuura TR,Petucci C,Lewandowski ED,Crawford PA,Muoio DM,Recchia FA,Kelly DP
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure.
Circulation. Heart failure10(12)(2017 Dec)
Uchihashi M,Hoshino A,Okawa Y,Ariyoshi M,Kaimoto S,Tateishi S,Ono K,Yamanaka R,Hato D,Fushimura Y,Honda S,Fukai K,Higuchi Y,Ogata T,Iwai-Kanai E,Matoba S
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
The Journal of cell biology216(3)675-693(2017 03)
Schatton D,Pla-Martin D,Marx MC,Hansen H,Mourier A,Nemazanyy I,Pessia A,Zentis P,Corona T,Kondylis V,Barth E,Schauss AC,Velagapudi V,Rugarli EI
E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy.
PloS one12(1)e0170066(2017)
Major JL,Dewan A,Salih M,Leddy JJ,Tuana BS
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
PLoS genetics12(9)e1006355(2016 Sep)
Wu Y,Wei FY,Kawarada L,Suzuki T,Araki K,Komohara Y,Fujimura A,Kaitsuka T,Takeya M,Oike Y,Suzuki T,Tomizawa K
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