Ifitm3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ifitm3
Entrez Gene ID	66141
Full Name	interferon induced transmembrane protein 3
Synonyms	1110004C05Rik,Cd225,Cdw217,DSPA2b,Fgls,IP15,mil-1
General protein information	Preferred Names interferon induced transmembrane protein 3 Names interferon-induced transmembrane protein 3 dispanin subfamily A member 2b fragilis protein ifitm-like protein 1 interferon-inducible protein 15
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F5

mRNA and Protein(s)

mRNA	Protein	Name
NM_025378.2	NP_079654.1	interferon-induced transmembrane protein 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ifitm3	NP_079654.1
Rattus norvegicus (Norway rat)	Ifitm3	NP_001129596.1
Homo sapiens (human)	IFITM3	NP_066362.2
Pan troglodytes (chimpanzee)	IFITM3	NP_001185686.1
Macaca mulatta (Rhesus monkey)	LOC100430243	XP_002798409.1

Gene Ontology
Bibliography

Related articles in PubMed

IFITM3 protects the heart during influenza virus infection.
Kenney AD, McMichael TM, Imas A, Chesarino NM, Zhang L, Dorn LE, Wu Q, Alfaour O, Amari F, Chen M, Zani A, Chemudupati M, Accornero F, Coppola V, Rajaram MVS, Yount JS
Proceedings of the National Academy of Sciences of the United States of America116(37)18607-18612(2019 Sep)

IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.
Yánez DC, Sahni H, Ross S, Solanki A, Lau CI, Papaioannou E, Barbarulo A, Powell R, Lange UC, Adams DJ, Barenco M, Ono M, D'Acquisto F, Furmanski AL, Crompton T
European journal of immunology49(1)66-78(2019 01)

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.
Bedford JG, O'Keeffe M, Reading PC, Wakim LM
PloS one14(1)e0210132(2019)

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells.
Petrillo C, Thorne LG, Unali G, Schiroli G, Giordano AMS, Piras F, Cuccovillo I, Petit SJ, Ahsan F, Noursadeghi M, Clare S, Genovese P, Gentner B, Naldini L, Towers GJ, Kajaste-Rudnitski A
Cell stem cell23(6)820-832.e9(2018 12)

Cloning of IP15, a pancreatitis-induced gene whose expression inhibits cell growth.
Ropolo A, Tomasini R, Grasso D, Dusetti NJ, Cerquetti MC, Iovanna JL, Vaccaro MI
Biochemical and biophysical research communications319(3)1001-9(2004 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ifitm3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ifitm3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18001	NM_025378.2 Latest version!	Mus musculus interferon induced transmembrane protein 3 (Ifitm3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ifitm3 ( NM_025378.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079654.1 Mus musculus interferon induced transmembrane protein 3 (Ifitm3), mRNA.

Price & Availability↑

CloneID	OMu18001
Clone ID Related Accession (Same CDS sequence)	NM_025378.2
Accession Version	NM_025378.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 414bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	interferon-induced transmembrane protein 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK003407.1. On Apr 6, 2007 this sequence version replaced NM_025378.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK003407.1, AY594690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAACCACA CTTCTCAAGC CTTCATCACC GCTGCCAGTG GAGGACAGCC CCCAAACTAC 
GAAAGAATCA AGGAAGAATA TGAGGTGGCT GAGATGGGGG CACCGCACGG ATCGGCTTCT 
GTCAGAACTA CTGTGATCAA CATGCCCAGA GAGGTGTCGG TGCCTGACCA TGTGGTCTGG 
TCCCTGTTCA ATACACTCTT CATGAACTTC TGCTGCCTGG GCTTCATAGC CTATGCCTAC 
TCCGTGAAGT CTAGGGATCG GAAGATGGTG GGTGATGTGA CTGGAGCCCA GGCCTACGCC 
TCCACTGCTA AGTGCCTGAA CATCAGCACC TTGGTCCTCA GCATCCTGAT GGTTGTTATC 
ACCATTGTTA GTGTCATCAT CATTGTTCTT AACGCTCAAA ACCTTCACAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079654.1
CDS	100..513
Translation	MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILMVVITIVSVIIIVLNAQNLHT

Target ORF information:

RefSeq Version	NM_025378.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon induced transmembrane protein 3 (Ifitm3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025378.2

ORF Insert Sequence:

ATGAACCACA CTTCTCAAGC CTTCATCACC GCTGCCAGTG GAGGACAGCC CCCAAACTAC 
GAAAGAATCA AGGAAGAATA TGAGGTGGCT GAGATGGGGG CACCGCACGG ATCGGCTTCT 
GTCAGAACTA CTGTGATCAA CATGCCCAGA GAGGTGTCGG TGCCTGACCA TGTGGTCTGG 
TCCCTGTTCA ATACACTCTT CATGAACTTC TGCTGCCTGG GCTTCATAGC CTATGCCTAC 
TCCGTGAAGT CTAGGGATCG GAAGATGGTG GGTGATGTGA CTGGAGCCCA GGCCTACGCC 
TCCACTGCTA AGTGCCTGAA CATCAGCACC TTGGTCCTCA GCATCCTGAT GGTTGTTATC 
ACCATTGTTA GTGTCATCAT CATTGTTCTT AACGCTCAAA ACCTTCACAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IFITM3 protects the heart during influenza virus infection.
Proceedings of the National Academy of Sciences of the United States of America116(37)18607-18612(2019 Sep)
Kenney AD,McMichael TM,Imas A,Chesarino NM,Zhang L,Dorn LE,Wu Q,Alfaour O,Amari F,Chen M,Zani A,Chemudupati M,Accornero F,Coppola V,Rajaram MVS,Yount JS

IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.
European journal of immunology49(1)66-78(2019 01)
Yánez DC,Sahni H,Ross S,Solanki A,Lau CI,Papaioannou E,Barbarulo A,Powell R,Lange UC,Adams DJ,Barenco M,Ono M,D'Acquisto F,Furmanski AL,Crompton T

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.
PloS one14(1)e0210132(2019)
Bedford JG,O'Keeffe M,Reading PC,Wakim LM

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells.
Cell stem cell23(6)820-832.e9(2018 12)
Petrillo C,Thorne LG,Unali G,Schiroli G,Giordano AMS,Piras F,Cuccovillo I,Petit SJ,Ahsan F,Noursadeghi M,Clare S,Genovese P,Gentner B,Naldini L,Towers GJ,Kajaste-Rudnitski A

Cloning of IP15, a pancreatitis-induced gene whose expression inhibits cell growth.
Biochemical and biophysical research communications319(3)1001-9(2004 Jul)
Ropolo A,Tomasini R,Grasso D,Dusetti NJ,Cerquetti MC,Iovanna JL,Vaccaro MI

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Ifitm3 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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