Ska2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ska2
Entrez Gene ID	66140
Full Name	spindle and kinetochore associated complex subunit 2
Synonyms	1110001A07Rik,C78640,Fam33a
General protein information	Preferred Names spindle and kinetochore associated complex subunit 2 Names spindle and kinetochore-associated protein 2 family with sequence similarity 33, member A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 C

mRNA and Protein(s)

mRNA	Protein	Name
NM_025377.3	NP_079653.1	spindle and kinetochore-associated protein 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ska2	NP_079653.1
Macaca mulatta (Rhesus monkey)	SKA2	XP_001107580.1
Rattus norvegicus (Norway rat)	Ska2	NP_001009624.1
Rattus norvegicus (Norway rat)	LOC691962	XP_001080369.2
Danio rerio (zebrafish)	im:7140390	NP_001186604.1
Canis lupus familiaris (dog)	SKA2	XP_003639344.1
Homo sapiens (human)	SKA2	NP_872426.1
Pan troglodytes (chimpanzee)	SKA2	XP_003953197.1
Bos taurus (cattle)	SKA2	NP_001033668.1
Gallus gallus (chicken)	SKA2	XP_415873.1
Xenopus tropicalis (tropical clawed frog)	ska2	XP_004911727.1

Gene Ontology
Bibliography

Related articles in PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Localization and function of the Ska complex during mouse oocyte meiotic maturation.
Zhang QH, Qi ST, Wang ZB, Yang CR, Wei YC, Chen L, Ouyang YC, Hou Y, Schatten H, Sun QY
Cell cycle (Georgetown, Tex.)11(5)909-16(2012 Mar)

Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor.
Rice L, Waters CE, Eccles J, Garside H, Sommer P, Kay P, Blackhall FH, Zeef L, Telfer B, Stratford I, Clarke R, Singh D, Stevens A, White A, Ray DW
The Journal of endocrinology198(3)499-509(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ska2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ska2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19484	NM_025377.3 Latest version!	Mus musculus spindle and kinetochore associated complex subunit 2 (Ska2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ska2 ( NM_025377.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079653.1 Mus musculus spindle and kinetochore associated complex subunit 2 (Ska2), mRNA.

Price & Availability↑

CloneID	OMu19484
Clone ID Related Accession (Same CDS sequence)	NM_025377.3
Accession Version	NM_025377.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550764800000
Organism	Mus musculus(house mouse)
Product	spindle and kinetochore-associated protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL713917.6. On Apr 29, 2007 this sequence version replaced NM_025377.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK017811.1, SRR1660813.167328.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGATTC TGATTTGGAT 
TACCTTCAAT ATAGGCTGGA ATATGAAGTC AAGACTAATC ACCCACATTC AGCAGGAGAG 
AAAAATGCAG TTACAGTTTT AAAGGAATTA TCAGCGATAA AGTCTCGCTA TCAAGCTTTA 
TGTGCACGCT TTAAGGCAGT TTCTGTTGAG CAAAAGGAGA CCAAGAGCTG CATTTGTGCT 
ACTTTGAACA AGACAATGAC CATGATACAA GAACTACAAA AGCAAACAAA CCTGGAGCTA 
ACTCTACTGA CTGAAGAAGA GAAAGCTGCA ACAGAGCCAT TAAAATCTCA TATGCCGGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079653.1
CDS	12..374
Translation	MEAEVDKLELMFQKADSDLDYLQYRLEYEVKTNHPHSAGEKNAVTVLKELSAIKSRYQALCARFKAVSVEQKETKSCICATLNKTMTMIQELQKQTNLELTLLTEEEKAATEPLKSHMPD

Target ORF information:

RefSeq Version	NM_025377.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus spindle and kinetochore associated complex subunit 2 (Ska2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025377.3

ORF Insert Sequence:

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGATTC TGATTTGGAT 
TACCTTCAAT ATAGGCTGGA ATATGAAGTC AAGACTAATC ACCCACATTC AGCAGGAGAG 
AAAAATGCAG TTACAGTTTT AAAGGAATTA TCAGCGATAA AGTCTCGCTA TCAAGCTTTA 
TGTGCACGCT TTAAGGCAGT TTCTGTTGAG CAAAAGGAGA CCAAGAGCTG CATTTGTGCT 
ACTTTGAACA AGACAATGAC CATGATACAA GAACTACAAA AGCAAACAAA CCTGGAGCTA 
ACTCTACTGA CTGAAGAAGA GAAAGCTGCA ACAGAGCCAT TAAAATCTCA TATGCCGGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Localization and function of the Ska complex during mouse oocyte meiotic maturation.
Cell cycle (Georgetown, Tex.)11(5)909-16(2012 Mar)
Zhang QH,Qi ST,Wang ZB,Yang CR,Wei YC,Chen L,Ouyang YC,Hou Y,Schatten H,Sun QY

Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor.
The Journal of endocrinology198(3)499-509(2008 Sep)
Rice L,Waters CE,Eccles J,Garside H,Sommer P,Kay P,Blackhall FH,Zeef L,Telfer B,Stratford I,Clarke R,Singh D,Stevens A,White A,Ray DW

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Ska2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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