SKA2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SKA2
Entrez Gene ID	348235
Full Name	spindle and kinetochore associated complex subunit 2
Synonyms	FAM33A
General protein information	Preferred Names spindle and kinetochore associated complex subunit 2 Names spindle and kinetochore-associated protein 2 family with sequence similarity 33, member A spindle and KT (kinetochore) associated 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q22
Disorder MIM:	616674

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100595.1	NP_001094065.1	spindle and kinetochore-associated protein 2 isoform 2
NM_182620.3	NP_872426.1	spindle and kinetochore-associated protein 2 isoform 1
NM_001330399.2	NP_001317328.1	spindle and kinetochore-associated protein 2 isoform 3
NM_001100595.2	NP_001094065.1	spindle and kinetochore-associated protein 2 isoform 2
NM_182620.4	NP_872426.1	spindle and kinetochore-associated protein 2 isoform 1
NM_001330399.1	NP_001317328.1	spindle and kinetochore-associated protein 2 isoform 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ska2	NP_079653.1
Macaca mulatta (Rhesus monkey)	SKA2	XP_001107580.1
Rattus norvegicus (Norway rat)	Ska2	NP_001009624.1
Rattus norvegicus (Norway rat)	LOC691962	XP_001080369.2
Danio rerio (zebrafish)	im:7140390	NP_001186604.1
Canis lupus familiaris (dog)	SKA2	XP_003639344.1
Homo sapiens (human)	SKA2	NP_872426.1
Pan troglodytes (chimpanzee)	SKA2	XP_003953197.1
Bos taurus (cattle)	SKA2	NP_001033668.1
Gallus gallus (chicken)	SKA2	XP_415873.1
Xenopus tropicalis (tropical clawed frog)	ska2	XP_004911727.1

Gene Ontology
Bibliography

Related articles in PubMed

SKA2 gene - A novel biomarker for latent anxiety and preterm birth prediction.
Ijabi J, Moradi-Sardareh H, Afrisham R, Seifi F, Ijabi R
European journal of obstetrics, gynecology, and reproductive biology237106-112(2019 Jun)

PRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer.
Wang Y, Zhang C, Mai L, Niu Y, Wang Y, Bu Y
BMB reports52(2)157-162(2019 Feb)

SKA2 mediates invasion and metastasis in human breast cancer via EMT.
Ren Z, Yang T, Zhang P, Liu K, Liu W, Wang P
Molecular medicine reports19(1)515-523(2019 Jan)

The N-terminal polypeptide derived from vMIP-II exerts its anti-tumor activity in human breast cancer by regulating lncRNA SPRY4-IT1.
Wu H, Wang Y, Chen T, Li Y, Wang H, Zhang L, Chen S, Wang W, Yang Q, Chen C
Bioscience reports38(5)(2018 10)

The stress response HPA-axis hormone, glucocorticoid, reduces cellular SKA complex gene expression.
Zhao J, Zhang P, He Z, Chen S, Golden T, Li L, Li M, Wu N
Psychiatry research260428-431(2018 02)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SKA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SKA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02270	NM_182620.4 Latest version!	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30890	NM_001100595.2 Latest version!	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu79507	NM_001330399.2 Latest version!	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu30890	NM_001100595.1	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu02270	NM_182620.3	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu79507	NM_001330399.1	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SKA2 ( NM_182620.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_872426.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02270
Clone ID Related Accession (Same CDS sequence)	NM_182620.3 , NM_182620.4
Accession Version	NM_182620.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514390400000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, BC106003.1, AC099850.7 and BQ019350.1. On Aug 3, 2007 this sequence version replaced NM_182620.2. Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056473.1, BC106003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974, SAMEA2157511 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGCTG 
TCACCACTGA CTAAAGAAGA GAAAACTGCG GCAGAGCAAT TCAAATTTCA CATGCCAGAT 
TTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872426.1
CDS	277..642
Translation	MEAEVDKLELMFQKAESDLDYIQYRLEYEIKTNHPDSASEKNPVTLLKELSVIKSRYQTLYARFKPVAVEQKESKSRICATVKKTMNMIQKLQKQTDLELSPLTKEEKTAAEQFKFHMPDL

Target ORF information:

RefSeq Version	NM_182620.3
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182620.3

ORF Insert Sequence:

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGCTG 
TCACCACTGA CTAAAGAAGA GAAAACTGCG GCAGAGCAAT TCAAATTTCA CATGCCAGAT 
TTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SKA2 ( NM_182620.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_872426.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02270
Clone ID Related Accession (Same CDS sequence)	NM_182620.3 , NM_182620.4
Accession Version	NM_182620.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, BC106003.1, AC099850.7 and BQ019350.1. On Nov 22, 2018 this sequence version replaced NM_182620.3. Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.506682.1, AK056473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974, SAMEA2157511 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000330137.12/ ENSP00000333433.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGCTG 
TCACCACTGA CTAAAGAAGA GAAAACTGCG GCAGAGCAAT TCAAATTTCA CATGCCAGAT 
TTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872426.1
CDS	24..389
Translation	MEAEVDKLELMFQKAESDLDYIQYRLEYEIKTNHPDSASEKNPVTLLKELSVIKSRYQTLYARFKPVAVEQKESKSRICATVKKTMNMIQKLQKQTDLELSPLTKEEKTAAEQFKFHMPDL

Target ORF information:

RefSeq Version	NM_182620.4
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182620.4

ORF Insert Sequence:

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGCTG 
TCACCACTGA CTAAAGAAGA GAAAACTGCG GCAGAGCAAT TCAAATTTCA CATGCCAGAT 
TTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SKA2 ( NM_001100595.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001094065.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30890
Clone ID Related Accession (Same CDS sequence)	NM_001100595.1 , NM_001100595.2
Accession Version	NM_001100595.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1541174400000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, DA133216.1, AC099850.7 and BQ019350.1. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. The biological validity of the predicted protein sequence needs to be experimentally verified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.4840.1, SRR1660803.108636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCGG AGGTGGGGCA CAATTTGGAG TCGCCGGAAA CTCCGGGCGG CGGAGGCTGG 
ACCAGAGTCG AGTTCCCTCC TCCTGCACCA AAGGGAGCCG CCACCGTCTG GTGTCTAAAC 
CGCCTCGGTT CCAGAAAGCT GAGTCTGATC TGGATTACAT TCAATACAGG CTGGAATATG 
AAATCAAGAC TAATCATCCT GATTCAGCAA GTGAGCTGTC ACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094065.1
CDS	357..584
Translation	MASEVGHNLESPETPGGGGWTRVEFPPPAPKGAATVWCLNRLGSRKLSLIWITFNTGWNMKSRLIILIQQVSCHH

Target ORF information:

RefSeq Version	NM_001100595.1
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100595.1

ORF Insert Sequence:

ATGGCCTCGG AGGTGGGGCA CAATTTGGAG TCGCCGGAAA CTCCGGGCGG CGGAGGCTGG 
ACCAGAGTCG AGTTCCCTCC TCCTGCACCA AAGGGAGCCG CCACCGTCTG GTGTCTAAAC 
CGCCTCGGTT CCAGAAAGCT GAGTCTGATC TGGATTACAT TCAATACAGG CTGGAATATG 
AAATCAAGAC TAATCATCCT GATTCAGCAA GTGAGCTGTC ACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SKA2 ( NM_001100595.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001094065.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30890
Clone ID Related Accession (Same CDS sequence)	NM_001100595.1 , NM_001100595.2
Accession Version	NM_001100595.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577980800000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, DA133216.1, AC099850.7 and BQ019350.1. On May 31, 2019 this sequence version replaced NM_001100595.1. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. The biological validity of the predicted protein sequence needs to be experimentally verified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.15465.1, SRR1660803.108636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCGG AGGTGGGGCA CAATTTGGAG TCGCCGGAAA CTCCGGGCGG CGGAGGCTGG 
ACCAGAGTCG AGTTCCCTCC TCCTGCACCA AAGGGAGCCG CCACCGTCTG GTGTCTAAAC 
CGCCTCGGTT CCAGAAAGCT GAGTCTGATC TGGATTACAT TCAATACAGG CTGGAATATG 
AAATCAAGAC TAATCATCCT GATTCAGCAA GTGAGCTGTC ACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094065.1
CDS	104..331
Translation	MASEVGHNLESPETPGGGGWTRVEFPPPAPKGAATVWCLNRLGSRKLSLIWITFNTGWNMKSRLIILIQQVSCHH

Target ORF information:

RefSeq Version	NM_001100595.2
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100595.2

ORF Insert Sequence:

ATGGCCTCGG AGGTGGGGCA CAATTTGGAG TCGCCGGAAA CTCCGGGCGG CGGAGGCTGG 
ACCAGAGTCG AGTTCCCTCC TCCTGCACCA AAGGGAGCCG CCACCGTCTG GTGTCTAAAC 
CGCCTCGGTT CCAGAAAGCT GAGTCTGATC TGGATTACAT TCAATACAGG CTGGAATATG 
AAATCAAGAC TAATCATCCT GATTCAGCAA GTGAGCTGTC ACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SKA2 ( NM_001330399.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317328.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu79507
Clone ID Related Accession (Same CDS sequence)	NM_001330399.2 , NM_001330399.1
Accession Version	NM_001330399.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577980800000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, DA020580.1, AC099850.7 and AK022820.1. On May 31, 2019 this sequence version replaced NM_001330399.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.888459.1, SRR1803613.97369.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGGTA 
ATGCTTTCAG TTGACAGCTG TCACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317328.1
CDS	24..353
Translation	MEAEVDKLELMFQKAESDLDYIQYRLEYEIKTNHPDSASEKNPVTLLKELSVIKSRYQTLYARFKPVAVEQKESKSRICATVKKTMNMIQKLQKQTDLEVMLSVDSCHH

Target ORF information:

RefSeq Version	NM_001330399.2
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330399.2

ORF Insert Sequence:

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGGTA 
ATGCTTTCAG TTGACAGCTG TCACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SKA2 ( NM_001330399.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317328.1 Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu79507
Clone ID Related Accession (Same CDS sequence)	NM_001330399.2 , NM_001330399.1
Accession Version	NM_001330399.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1541174400000
Organism	Homo sapiens(human)
Product	spindle and kinetochore-associated protein 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB158057.1, DA020580.1, AC099850.7 and AK022820.1. On Aug 29, 2016 this sequence version replaced XM_011524745.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.97369.1, SRR1803613.219627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGGTA 
ATGCTTTCAG TTGACAGCTG TCACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317328.1
CDS	277..606
Translation	MEAEVDKLELMFQKAESDLDYIQYRLEYEIKTNHPDSASEKNPVTLLKELSVIKSRYQTLYARFKPVAVEQKESKSRICATVKKTMNMIQKLQKQTDLEVMLSVDSCHH

Target ORF information:

RefSeq Version	NM_001330399.1
Organism	Homo sapiens(human)
Definition	Homo sapiens spindle and kinetochore associated complex subunit 2 (SKA2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330399.1

ORF Insert Sequence:

ATGGAGGCGG AGGTCGATAA GCTGGAACTG ATGTTCCAGA AAGCTGAGTC TGATCTGGAT 
TACATTCAAT ACAGGCTGGA ATATGAAATC AAGACTAATC ATCCTGATTC AGCAAGTGAG 
AAAAATCCAG TTACACTCTT AAAGGAATTG TCAGTGATAA AGTCTCGATA TCAAACTTTG 
TATGCCCGCT TTAAACCAGT TGCTGTTGAG CAGAAAGAGA GTAAGAGCCG CATTTGTGCT 
ACTGTGAAAA AGACTATGAA TATGATACAA AAACTACAGA AGCAAACAGA CCTGGAGGTA 
ATGCTTTCAG TTGACAGCTG TCACCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SKA2 gene - A novel biomarker for latent anxiety and preterm birth prediction.
European journal of obstetrics, gynecology, and reproductive biology237106-112(2019 Jun)
Ijabi J,Moradi-Sardareh H,Afrisham R,Seifi F,Ijabi R

PRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer.
BMB reports52(2)157-162(2019 Feb)
Wang Y,Zhang C,Mai L,Niu Y,Wang Y,Bu Y

SKA2 mediates invasion and metastasis in human breast cancer via EMT.
Molecular medicine reports19(1)515-523(2019 Jan)
Ren Z,Yang T,Zhang P,Liu K,Liu W,Wang P

The N-terminal polypeptide derived from vMIP-II exerts its anti-tumor activity in human breast cancer by regulating lncRNA SPRY4-IT1.
Bioscience reports38(5)(2018 10)
Wu H,Wang Y,Chen T,Li Y,Wang H,Zhang L,Chen S,Wang W,Yang Q,Chen C

The stress response HPA-axis hormone, glucocorticoid, reduces cellular SKA complex gene expression.
Psychiatry research260428-431(2018 02)
Zhao J,Zhang P,He Z,Chen S,Golden T,Li L,Li M,Wu N

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SKA2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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