TMPRSS2 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMPRSS2
Entrez Gene ID	50528
Full Name	transmembrane protease, serine 2
Synonyms	D16Ertd61e
General protein information	Preferred Names transmembrane protease, serine 2 Names transmembrane protease serine 2 epitheliasin plasmic transmembrane protein X
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 16 Map Location: 16 C4\|16 57.53 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006523064.3	XP_006523127.1	transmembrane protease serine 2 isoform X1
XM_006523065.2	XP_006523128.1	transmembrane protease serine 2 isoform X1
NM_015775.2	NP_056590.2	transmembrane protease serine 2
XM_006523064.2	XP_006523127.1	transmembrane protease serine 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TMPRSS2	XP_531467.2
Canis lupus familiaris (dog)	TMPRSS2	XP_005639053.1
Mus musculus (house mouse)	Tmprss2	NP_056590.2
Xenopus tropicalis (tropical clawed frog)	LOC101731874	XP_004912264.1
Homo sapiens (human)	TMPRSS2	NP_001128571.1
Danio rerio (zebrafish)	tmprss2	NP_001008623.1
Macaca mulatta (Rhesus monkey)	LOC715138	XP_001107275.2
Bos taurus (cattle)	TMPRSS2	NP_001075054.1
Rattus norvegicus (Norway rat)	Tmprss2	NP_569108.2
Gallus gallus (chicken)	TMPRSS2	XP_416737.3
Caenorhabditis elegans (roundworm)	svh-1	NP_501379.2

Gene Ontology
Bibliography

Related articles in PubMed

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection.
Iwata-Yoshikawa N, Okamura T, Shimizu Y, Hasegawa H, Takeda M, Nagata N
Journal of virology93(6)(2019 03)

Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer.
Ding Y, Li N, Dong B, Guo W, Wei H, Chen Q, Yuan H, Han Y, Chang H, Kan S, Wang X, Pan Q, Wu P, Peng C, Qiu T, Li Q, Gao D, Xue W, Qin J
The Journal of clinical investigation129(2)759-773(2019 02)

Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Sandoval GJ, Pulice JL, Pakula H, Schenone M, Takeda DY, Pop M, Boulay G, Williamson KE, McBride MJ, Pan J, St Pierre R, Hartman E, Garraway LA, Carr SA, Rivera MN, Li Z, Ronco L, Hahn WC, Kadoch C
Molecular cell71(4)554-566.e7(2018 08)

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
Earnest JT, Hantak MP, Li K, McCray PB Jr, Perlman S, Gallagher T
PLoS pathogens13(7)e1006546(2017 Jul)

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Dardenne E, Beltran H, Benelli M, Gayvert K, Berger A, Puca L, Cyrta J, Sboner A, Noorzad Z, MacDonald T, Cheung C, Yuen KS, Gao D, Chen Y, Eilers M, Mosquera JM, Robinson BD, Elemento O, Rubin MA, Demichelis F, Rickman DS
Cancer cell30(4)563-577(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TMPRSS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMPRSS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20152	NM_015775.2 Latest version!	Mus musculus transmembrane protease, serine 2 (Tmprss2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OMu20152	XM_006523065.2 Latest version!	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OMu20152	XM_006523064.3 Latest version!	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OMu20152	XM_006523064.2	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMPRSS2 ( XM_006523064.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006523127.1 Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20152
Clone ID Related Accession (Same CDS sequence)	XM_006523064.3 , XM_006523065.2 , NM_015775.2 , XM_006523064.2
Accession Version	XM_006523064.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1423324800000
Organism	Mus musculus(House mouse)
Product	transmembrane protease serine 2 isoform X1
Comment

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006523127.1

Translation

MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS

Target ORF information:

RefSeq Version	XM_006523064.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523064.2

ORF Insert Sequence:

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS2 ( NM_015775.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_056590.2 Mus musculus transmembrane protease, serine 2 (Tmprss2), mRNA.

Price & Availability↑

CloneID	OMu20152
Clone ID Related Accession (Same CDS sequence)	XM_006523064.3 , XM_006523065.2 , NM_015775.2 , XM_006523064.2
Accession Version	NM_015775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574611200000
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054348.1. On Aug 28, 2003 this sequence version replaced NM_015775.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054348.1, AK141350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056590.2
CDS	231..1703
Translation	MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS

Target ORF information:

RefSeq Version	NM_015775.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protease, serine 2 (Tmprss2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015775.2

ORF Insert Sequence:

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS2 ( XM_006523064.3 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006523127.1 Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20152
Clone ID Related Accession (Same CDS sequence)	XM_006523064.3 , XM_006523065.2 , NM_015775.2 , XM_006523064.2
Accession Version	XM_006523064.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006523064.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006523127.1
CDS	104..1576
Translation	MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS

Target ORF information:

RefSeq Version	XM_006523064.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523064.3

ORF Insert Sequence:

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS2 ( XM_006523065.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006523128.1 Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X2, mRNA.

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CloneID	OMu20152
Clone ID Related Accession (Same CDS sequence)	XM_006523064.3 , XM_006523065.2 , NM_015775.2 , XM_006523064.2
Accession Version	XM_006523065.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	transmembrane protease serine 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000082.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006523065.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006523128.1
CDS	77..1549
Translation	MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS

Target ORF information:

RefSeq Version	XM_006523065.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protease, serine 2 (Tmprss2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006523065.2

ORF Insert Sequence:

ATGGCATTGA ACTCAGGGTC ACCTCCAGGA ATCGGACCTT GCTATGAGAA CCACGGGTAT 
CAGTCTGAGC ACATCTGTCC TCCGAGACCA CCAGTGGCTC CCAATGGCTA CAACTTGTAT 
CCAGCCCAGT ACTACCCATC TCCAGTGCCT CAGTATGCTC CGAGGATTAC AACGCAAGCC 
TCAACATCTG TCATCCACAC ACATCCCAAG TCCTCAGGAG CACTGTGCAC CTCAAAGTCT 
AAGAAATCGC TGTGTTTAGC CCTCGCCCTG GGCACTGTCC TCACGGGAGC TGCTGTGGCT 
GCTGTCTTGC TTTGGAGGTT CTGGGACAGC AACTGTTCTA CGTCTGAGAT GGAGTGTGGG 
TCTTCAGGCA CATGCATCAG CTCTTCTCTC TGGTGTGACG GGGTAGCACA TTGTCCCAAC 
GGAGAAGATG AGAACCGTTG TGTTCGTCTC TACGGACAAA GCTTCATCCT CCAGGTTTAC 
TCATCTCAGA GGAAAGCCTG GTATCCCGTG TGCCAGGATG ATTGGAGTGA GAGCTACGGG 
AGAGCAGCAT GTAAAGACAT GGGATACAAG AACAATTTTT ATTCTAGCCA AGGGATACCA 
GACCAGAGCG GGGCAACGAG CTTTATGAAG CTGAATGTGA GCTCAGGCAA CGTTGACCTC 
TATAAAAAAC TCTACCACAG TGACTCATGT TCATCCCGCA TGGTGGTTTC TTTGCGCTGT 
ATAGAATGCG GGGTTCGCTC AGTGAAACGC CAGAGCAGGA TTGTGGGTGG ATTGAATGCC 
TCACCAGGAG ACTGGCCCTG GCAGGTCAGC CTGCACGTCC AAGGCGTCCA CGTCTGCGGA 
GGCTCCATCA TCACCCCCGA GTGGATTGTG ACGGCCGCCC ACTGTGTGGA AGAACCCCTC 
AGCAGCCCGA GGTACTGGAC GGCATTTGCG GGAATTCTGA GACAGTCTCT CATGTTCTAT 
GGAAGTAGAC ACCAGGTAGA AAAAGTAATT TCCCATCCAA ATTACGACTC TAAGACCAAG 
AATAACGACA TTGCTCTCAT GAAGCTGCAG ACACCTTTGG CTTTTAATGA TCTAGTGAAG 
CCAGTGTGTC TGCCGAACCC AGGCATGATG CTAGACCTAG ACCAGGAATG CTGGATTTCG 
GGGTGGGGGG CCACCTATGA GAAAGGGAAG ACCTCGGACG TGTTGAATGC TGCCATGGTA 
CCCTTGATCG AGCCCTCCAA ATGTAATAGT AAATACATAT ACAACAACCT AATCACACCA 
GCCATGATCT GTGCCGGCTT CCTCCAGGGG TCTGTCGACT CTTGCCAGGG AGACAGTGGA 
GGGCCGCTGG TTACTTTGAA GAATGGGATC TGGTGGCTGA TTGGGGACAC GAGCTGGGGC 
TCGGGCTGTG CCAAGGCACT CAGACCTGGA GTATACGGGA ACGTGACGGT ATTTACAGAT 
TGGATCTACC AGCAAATGAG GGCGAACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection.
Journal of virology93(6)(2019 03)
Iwata-Yoshikawa N,Okamura T,Shimizu Y,Hasegawa H,Takeda M,Nagata N

Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer.
The Journal of clinical investigation129(2)759-773(2019 02)
Ding Y,Li N,Dong B,Guo W,Wei H,Chen Q,Yuan H,Han Y,Chang H,Kan S,Wang X,Pan Q,Wu P,Peng C,Qiu T,Li Q,Gao D,Xue W,Qin J

Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Molecular cell71(4)554-566.e7(2018 08)
Sandoval GJ,Pulice JL,Pakula H,Schenone M,Takeda DY,Pop M,Boulay G,Williamson KE,McBride MJ,Pan J,St Pierre R,Hartman E,Garraway LA,Carr SA,Rivera MN,Li Z,Ronco L,Hahn WC,Kadoch C

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
PLoS pathogens13(7)e1006546(2017 Jul)
Earnest JT,Hantak MP,Li K,McCray PB Jr,Perlman S,Gallagher T

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Cancer cell30(4)563-577(2016 10)
Dardenne E,Beltran H,Benelli M,Gayvert K,Berger A,Puca L,Cyrta J,Sboner A,Noorzad Z,MacDonald T,Cheung C,Yuen KS,Gao D,Chen Y,Eilers M,Mosquera JM,Robinson BD,Elemento O,Rubin MA,Demichelis F,Rickman DS

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TMPRSS2 cDNA ORF clone, Mus musculus(House mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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