Nlrp4e cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nlrp4e
Entrez Gene ID	446099
Full Name	NLR family, pyrin domain containing 4E
Synonyms	4930406H16Rik,Nalp-epsilon,Nalp4e,Nlrp4
General protein information	Preferred Names NLR family, pyrin domain containing 4E Names NACHT, LRR and PYD domains-containing protein 4E NACHT, leucine rich repeat and PYD containing 4E NALP, epsilon NLR family, pyrin domain containing 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004194.2	NP_001004194.2	NACHT, LRR and PYD domains-containing protein 4E
XM_030242760.1	XP_030098620.1	NACHT, LRR and PYD domains-containing protein 4E isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NLRP4	NP_604393.2
Macaca mulatta (Rhesus monkey)	NLRP4	XP_001090438.1
Mus musculus (house mouse)	Nlrp4e	NP_001004194.2
Mus musculus (house mouse)	Nlrp4c	NP_113566.2
Rattus norvegicus (Norway rat)	Nlrp4	NP_001165635.1
Pan troglodytes (chimpanzee)	NLRP4	XP_524404.4

Gene Ontology
Bibliography

Related articles in PubMed

USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome.
Lin M, Zhao Z, Yang Z, Meng Q, Tan P, Xie W, Qin Y, Wang RF, Cui J
Molecular cell64(2)267-281(2016 10)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Developmental expression and possible functional roles of mouse Nlrp4e in preimplantation embryos.
Chang BH, Liu X, Liu J, Quan FS, Guo ZK, Zhang Y
In vitro cellular & developmental biology. Animal49(7)548-53(2013 Aug)

Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice.
DeSantis DA, Ko CW, Liu Y, Liu X, Hise AG, Nunez G, Croniger CM
Mediators of inflammation2013751374(2013)

Age-associated alteration of gene expression patterns in mouse oocytes.
Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS
Human molecular genetics13(19)2263-78(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nlrp4e gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nlrp4e cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu14180	NM_001004194.2 Latest version!	Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu89562	XM_030242760.1 Latest version!	Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nlrp4e ( NM_001004194.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001004194.2 Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), mRNA.

Price & Availability↑

CloneID	OMu14180
Clone ID Related Accession (Same CDS sequence)	NM_001004194.2
Accession Version	NM_001004194.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2937bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	NACHT, LRR and PYD domains-containing protein 4E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC150900.5. On Aug 25, 2009 this sequence version replaced NM_001004194.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC139319.1, AY596197.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849384 [ECO:0000350] ##Evidence-Data-END##

ATGGCATCAT TTTTTTCTGA TTTTGGCCTT ATGTGGTACT TGGAAGAGCT AAACAAGAAA 
GAATTCATGA AATTTAAGGA ATTACTCCAA CAGGAGATTT TGCAGTTGGG GCTGAAACAC 
ATTTCTTGGA CCGAAGTGAA GAAGGCATCT CGTGAAGACC TTGCCAACTT ACTGTTGAAA 
CATTATGAGG AGAAGAAAGC CTGGGATATG ACCTTCAAAA TCTTCCAGAA GATGAATAGG 
CAGGATCTCA TGGAGAGGGC AGGAAGAGAG ATTGCTGGAC ACTCAAAGTT ATATCAAGTT 
CATTTGAAGA AGAAGCTGAC CCATGATTAT GCCAGAAAGT TTAACATCAA AGATCAAGAT 
TCCCTTAAGC AGAAATTTAC CCAGGATGAC TGTGATCATT TTGAGAACCT TCTCATATCA 
AAGGCGACTG GAAAGAAGCC ACACATGGTG TTTCTGCAAG GAGTGGCGGG AATTGGCAAG 
TCACTGATGT TGACAAAGTT AATGCTTGCC TGGTCAGAAG GCATGGTGTT TCAGAACAAA 
TTCTCCTACA TCTTCTACTT CTGCTGTCAA GATGTGAAGA AGATGAAGAG AGCAAGCCTG 
GCAGAATTGA TCTCCAAAGA GTGGCCCAAC GCCTCAGCTC CCATAGAGGA GATCCTGTCC 
CAACCGGAGA AACTCTTATT TGTCATCGAC AACTTGGAAG TGATGGAATG TGATATGTCT 
GAATGGGAGT CGGAGCTGTG TGATGACTGC ATGGAGAAGC AGCCAGTGAA TATACTGATG 
AGCAGTTTGC TCAGGAGGAA GATGCTCCCT GAATCCTCTT TCCTCGTCTC TGCTACCCCA 
GAGACTTTTG AGAAAATAGA GGACAGGATT GAGTGCACAA ATGTAAAAAT GATGGCAGGA 
TTCAATGAGA GCAGTATTAA GGTGTATTTC TACAGCTTGT TCCAAGATAG GAACAGAACC 
CAGGAAATTT TCAGTTTGGT GAGAGAAAAT GAGCAGCTGT TCTCTGTATG TCAAGTCCCT 
GTGCTCTGCT GGATGGTGGC TACTTGTCTA AAAAAAGAGA TAGAGAAGGG AAGAGACCCA 
GTCTCAATCT GCCGACGTAT CACTTCCCTG TATACCACTT ACATCTTCAA TTTGTTCATT 
CCCCACAGTG CCCAATATCC AAGTAAGAAA AGCCAAGACC AGCTGCAGGG CTTATGTTCT 
CTGGCTGCTG AGGGCATGTG GACTGACACA TTTGTGTTTG CTGAGGAGGC TCTCAGGAGA 
AATGGGATCA TGGACTCTGA TATCTCCACA CTGCTGGACG TAAGGATCCT TGAAAAGAGC 
AAGGAATCTG AAAAATCTTA CATTTTCCTC CACCCATCTA TCCAGGAGGT CTGTGCTGCC 
ATCTTTCATC TGCTAAAGAG CCATGTAGAC CATCCTAGCC AGGATGTCAA AAGTATAGAG 
GCACTCATAT TTACATTTCT AAAGAAAGTC AAAATACAGT GGATTTTTTT TGGCTCTTTC 
ATCTTTGGCC TTTTACATGA ATCAGAACAA AAAAAGCTAG AGGCATTTTT TGGCCACCAG 
TTGTCCCAAG AAATAAAACG TCAGTTGTAT CAGTGCCTGG AAACCATAAG TGGCAATAAA 
GAGCTTCAAG AACAGATAGA TGGCATGAAG CTGTTTTACT GTCTGTTTGA GATGGACGAT 
GAAGCCTTCT TACCACAAGT TATGAACTGT ATGGAACAGA TTAAATTTGT GGCTAAGGAT 
TATTCTGATG TTATTGTTGC TGCCCACTGC TTACAACACT GTTCTACACT GAAAAAACTA 
TCCTTGTCAA CCCAGAATAT CCTGAGTGAA GGTCAAGAAC ACAGCTATAC GGAAAAGCTA 
CTCATCTGTT GGCATCATGT GTGCTCTGTG CTCACAAGCA GTAAGGATAT CCACGTACTC 
CAAGTGAAAG ACACTAATTT CAATGAAAGA GCCTTTTTGG TCTTGTATAG TCATCTGAAG 
TACCCCAGCT GCATCCTTAA AGTACTTGAG GTAAATAATG TGACTTTGCT TTGTGATAAC 
CGCCTGTTAT TTGAGTTGAT TCAGAACCAA CGTTTGCAGC TCTTGAACCT CAGCCTCACA 
TTCCTGTCCC ACAATGATGT GAAACTGTTG TGTGATGTCT TGAACCAGGC AGAGTGCAAC 
ATAGAAAAGC TGATGGTAGC AGACTGTAAC CTTTCACCTG ATGACTGCAA GGTCTTTGTC 
TCCGTCCTGA TCAGCAGCAA GATGTTGAAG CATCTTAATT TGTCATCTAA CAACTTGGAC 
AAAGGGATAT CCTCTCTGTC CAAGGCTTTG TGCCACCCAG ACTGTGTTCT GAAGAACTTG 
GTGTTAGCCA AATGTTCCCT CAGTGAGGAA TGTTGGCACT ACCTTTCAGA AGTTCTTAGG 
CGGAACAAAA CCTTGACCCA CCTAGATATC AGCTTCAATG ACCTAAAGGA CGAAGGGCTG 
AAGGTTCTCT GTGGGGCTCT CACTCTCCCA GACAGTGTCC TCATATCACT GAGTGTAAGA 
TATTGTCTCA TCACCACTAG TGGTTGCCAG GACCTGGCTG AAGTCTTGAG AAACAACCAG 
AACCTGAGGA ACCTACAGAT TTCAAACAAT AAAATAGAAG ATGCTGGTGT GAAGCTCCTG 
TGTGATGCTA TAAAACATCC CAACTGCCAC TTAGAAAATA TTGGATTGGA AGCCTGCGCA 
CTAACTGGTG CCTGCTGTGA GGACCTTGCT TCTTCTTTTA CCCACTGTAA GACCCTGTTG 
GGAATCAACC TGCAGGAGAA CGCCTTGGAC CACAGTGGAT TGGTTGCACT GTTTGAGGCT 
ATGAAACAGC AACAGTGTAC CGTGAATTTA CGTGGACTTC GAATTACTGA CTTTGATAAG 
GAAACCCAGG AGTTCCTGAT GGCTGAGAAA GAGAAAAACC CATACTTGAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004194.2
CDS	91..3027
Translation	MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI

Target ORF information:

RefSeq Version	NM_001004194.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004194.2

ORF Insert Sequence:

ATGGCATCAT TTTTTTCTGA TTTTGGCCTT ATGTGGTACT TGGAAGAGCT AAACAAGAAA 
GAATTCATGA AATTTAAGGA ATTACTCCAA CAGGAGATTT TGCAGTTGGG GCTGAAACAC 
ATTTCTTGGA CCGAAGTGAA GAAGGCATCT CGTGAAGACC TTGCCAACTT ACTGTTGAAA 
CATTATGAGG AGAAGAAAGC CTGGGATATG ACCTTCAAAA TCTTCCAGAA GATGAATAGG 
CAGGATCTCA TGGAGAGGGC AGGAAGAGAG ATTGCTGGAC ACTCAAAGTT ATATCAAGTT 
CATTTGAAGA AGAAGCTGAC CCATGATTAT GCCAGAAAGT TTAACATCAA AGATCAAGAT 
TCCCTTAAGC AGAAATTTAC CCAGGATGAC TGTGATCATT TTGAGAACCT TCTCATATCA 
AAGGCGACTG GAAAGAAGCC ACACATGGTG TTTCTGCAAG GAGTGGCGGG AATTGGCAAG 
TCACTGATGT TGACAAAGTT AATGCTTGCC TGGTCAGAAG GCATGGTGTT TCAGAACAAA 
TTCTCCTACA TCTTCTACTT CTGCTGTCAA GATGTGAAGA AGATGAAGAG AGCAAGCCTG 
GCAGAATTGA TCTCCAAAGA GTGGCCCAAC GCCTCAGCTC CCATAGAGGA GATCCTGTCC 
CAACCGGAGA AACTCTTATT TGTCATCGAC AACTTGGAAG TGATGGAATG TGATATGTCT 
GAATGGGAGT CGGAGCTGTG TGATGACTGC ATGGAGAAGC AGCCAGTGAA TATACTGATG 
AGCAGTTTGC TCAGGAGGAA GATGCTCCCT GAATCCTCTT TCCTCGTCTC TGCTACCCCA 
GAGACTTTTG AGAAAATAGA GGACAGGATT GAGTGCACAA ATGTAAAAAT GATGGCAGGA 
TTCAATGAGA GCAGTATTAA GGTGTATTTC TACAGCTTGT TCCAAGATAG GAACAGAACC 
CAGGAAATTT TCAGTTTGGT GAGAGAAAAT GAGCAGCTGT TCTCTGTATG TCAAGTCCCT 
GTGCTCTGCT GGATGGTGGC TACTTGTCTA AAAAAAGAGA TAGAGAAGGG AAGAGACCCA 
GTCTCAATCT GCCGACGTAT CACTTCCCTG TATACCACTT ACATCTTCAA TTTGTTCATT 
CCCCACAGTG CCCAATATCC AAGTAAGAAA AGCCAAGACC AGCTGCAGGG CTTATGTTCT 
CTGGCTGCTG AGGGCATGTG GACTGACACA TTTGTGTTTG CTGAGGAGGC TCTCAGGAGA 
AATGGGATCA TGGACTCTGA TATCTCCACA CTGCTGGACG TAAGGATCCT TGAAAAGAGC 
AAGGAATCTG AAAAATCTTA CATTTTCCTC CACCCATCTA TCCAGGAGGT CTGTGCTGCC 
ATCTTTCATC TGCTAAAGAG CCATGTAGAC CATCCTAGCC AGGATGTCAA AAGTATAGAG 
GCACTCATAT TTACATTTCT AAAGAAAGTC AAAATACAGT GGATTTTTTT TGGCTCTTTC 
ATCTTTGGCC TTTTACATGA ATCAGAACAA AAAAAGCTAG AGGCATTTTT TGGCCACCAG 
TTGTCCCAAG AAATAAAACG TCAGTTGTAT CAGTGCCTGG AAACCATAAG TGGCAATAAA 
GAGCTTCAAG AACAGATAGA TGGCATGAAG CTGTTTTACT GTCTGTTTGA GATGGACGAT 
GAAGCCTTCT TACCACAAGT TATGAACTGT ATGGAACAGA TTAAATTTGT GGCTAAGGAT 
TATTCTGATG TTATTGTTGC TGCCCACTGC TTACAACACT GTTCTACACT GAAAAAACTA 
TCCTTGTCAA CCCAGAATAT CCTGAGTGAA GGTCAAGAAC ACAGCTATAC GGAAAAGCTA 
CTCATCTGTT GGCATCATGT GTGCTCTGTG CTCACAAGCA GTAAGGATAT CCACGTACTC 
CAAGTGAAAG ACACTAATTT CAATGAAAGA GCCTTTTTGG TCTTGTATAG TCATCTGAAG 
TACCCCAGCT GCATCCTTAA AGTACTTGAG GTAAATAATG TGACTTTGCT TTGTGATAAC 
CGCCTGTTAT TTGAGTTGAT TCAGAACCAA CGTTTGCAGC TCTTGAACCT CAGCCTCACA 
TTCCTGTCCC ACAATGATGT GAAACTGTTG TGTGATGTCT TGAACCAGGC AGAGTGCAAC 
ATAGAAAAGC TGATGGTAGC AGACTGTAAC CTTTCACCTG ATGACTGCAA GGTCTTTGTC 
TCCGTCCTGA TCAGCAGCAA GATGTTGAAG CATCTTAATT TGTCATCTAA CAACTTGGAC 
AAAGGGATAT CCTCTCTGTC CAAGGCTTTG TGCCACCCAG ACTGTGTTCT GAAGAACTTG 
GTGTTAGCCA AATGTTCCCT CAGTGAGGAA TGTTGGCACT ACCTTTCAGA AGTTCTTAGG 
CGGAACAAAA CCTTGACCCA CCTAGATATC AGCTTCAATG ACCTAAAGGA CGAAGGGCTG 
AAGGTTCTCT GTGGGGCTCT CACTCTCCCA GACAGTGTCC TCATATCACT GAGTGTAAGA 
TATTGTCTCA TCACCACTAG TGGTTGCCAG GACCTGGCTG AAGTCTTGAG AAACAACCAG 
AACCTGAGGA ACCTACAGAT TTCAAACAAT AAAATAGAAG ATGCTGGTGT GAAGCTCCTG 
TGTGATGCTA TAAAACATCC CAACTGCCAC TTAGAAAATA TTGGATTGGA AGCCTGCGCA 
CTAACTGGTG CCTGCTGTGA GGACCTTGCT TCTTCTTTTA CCCACTGTAA GACCCTGTTG 
GGAATCAACC TGCAGGAGAA CGCCTTGGAC CACAGTGGAT TGGTTGCACT GTTTGAGGCT 
ATGAAACAGC AACAGTGTAC CGTGAATTTA CGTGGACTTC GAATTACTGA CTTTGATAAG 
GAAACCCAGG AGTTCCTGAT GGCTGAGAAA GAGAAAAACC CATACTTGAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nlrp4e ( XM_030242760.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030098620.1 Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu89562
Clone ID Related Accession (Same CDS sequence)	XM_030242760.1
Accession Version	XM_030242760.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2217bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	NACHT, LRR and PYD domains-containing protein 4E isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCAT TTTTTTCTGA TTTTGGCCTT ATGTGGTACT TGGAAGAGCT AAACAAGAAA 
GAATTCATGA AATTTAAGGA ATTACTCCAA CAGGAGATTT TGCAGTTGGG GCTGAAACAC 
ATTTCTTGGA CCGAAGTGAA GAAGGCATCT CGTGAAGACC TTGCCAACTT ACTGTTGAAA 
CATTATGAGG AGAAGAAAGC CTGGGATATG ACCTTCAAAA TCTTCCAGAA GATGAATAGG 
CAGGATCTCA TGGAGAGGGC AGGAAGAGAG ATTGCTGATG TTGTGGATTT TTTTTCCCTT 
GTGCTCACTG ACTCAGGACA CTCAAAGTTA TATCAAGTTC ATTTGAAGAA GAAGCTGACC 
CATGATTATG CCAGAAAGTT TAACATCAAA GATCAAGATT CCCTTAAGCA GAAATTTACC 
CAGGATGACT GTGATCATTT TGAGAACCTT CTCATATCAA AGGCGACTGG AAAGAAGCCA 
CACATGGTGT TTCTGCAAGG AGTGGCGGGA ATTGGCAAGT CACTGATGTT GACAAAGTTA 
ATGCTTGCCT GGTCAGAAGG CATGGTGTTT CAGAACAAAT TCTCCTACAT CTTCTACTTC 
TGCTGTCAAG ATGTGAAGAA GATGAAGAGA GCAAGCCTGG CAGAATTGAT CTCCAAAGAG 
TGGCCCAACG CCTCAGCTCC CATAGAGGAG ATCCTGTCCC AACCGGAGAA ACTCTTATTT 
GTCATCGACA ACTTGGAAGT GATGGAATGT GATATGTCTG AATGGGAGTC GGAGCTGTGT 
GATGACTGCA TGGAGAAGCA GCCAGTGAAT ATACTGATGA GCAGTTTGCT CAGGAGGAAG 
ATGCTCCCTG AATCCTCTTT CCTCGTCTCT GCTACCCCAG AGACTTTTGA GAAAATAGAG 
GACAGGATTG AGTGCACAAA TGTAAAAATG ATGGCAGGAT TCAATGAGAG CAGTATTAAG 
GTGTATTTCT ACAGCTTGTT CCAAGATAGG AACAGAACCC AGGAAATTTT CAGTTTGGTG 
AGAGAAAATG AGCAGCTGTT CTCTGTATGT CAAGTCCCTG TGCTCTGCTG GATGGTGGCT 
ACTTGTCTAA AAAAAGAGAT AGAGAAGGGA AGAGACCCAG TCTCAATCTG CCGACGTATC 
ACTTCCCTGT ATACCACTTA CATCTTCAAT TTGTTCATTC CCCACAGTGC CCAATATCCA 
AGTAAGAAAA GCCAAGACCA GCTGCAGGGC TTATGTTCTC TGGCTGCTGA GGGCATGTGG 
ACTGACACAT TTGTGTTTGC TGAGGAGGCT CTCAGGAGAA ATGGGATCAT GGACTCTGAT 
ATCTCCACAC TGCTGGACGT AAGGATCCTT GAAAAGAGCA AGGAATCTGA AAAATCTTAC 
ATTTTCCTCC ACCCATCTAT CCAGGAGGTC TGTGCTGCCA TCTTTCATCT GCTAAAGAGC 
CATGTAGACC ATCCTAGCCA GGATGTCAAA AGTATAGAGG CACTCATATT TACATTTCTA 
AAGAAAGTCA AAATACAGTG GATTTTTTTT GGCTCTTTCA TCTTTGGCCT TTTACATGAA 
TCAGAACAAA AAAAGCTAGA GGCATTTTTT GGCCACCAGT TGTCCCAAGA AATAAAACGT 
CAGTTGTATC AGTGCCTGGA AACCATAAGT GGCAATAAAG AGCTTCAAGA ACAGATAGAT 
GGCATGAAGC TGTTTTACTG TCTGTTTGAG ATGGACGATG AAGCCTTCTT ACCACAAGTT 
ATGAACTGTA TGGAACAGAT TAAATTTGTG GCTAAGGATT ATTCTGATGT TATTGTTGCT 
GCCCACTGCT TACAACACTG TTCTACACTG AAAAAACTAT CCTTGTCAAC CCAGAATATC 
CTGAGTGAAG GTCAAGAACA CAGCTATACG GAAAAGCTAC TCATCTGTTG GCATCATGTG 
TGCTCTGTGC TCACAAGCAG TAAGGATATC CACGTACTCC AAGTGAAAGA CACTAATTTC 
AATGAAAGAG CCTTTTTGGT CTTGTATAGT CATCTGAAGT ACCCCAGCTG CATCCTTAAA 
GTACTTGAGG TAAATAATGT GACTTTGCTT TGTGATAACC GCCTGTTATT TGAGTTGATT 
CAGAACCAAC GTTTGCAGCT CTTGAACCTC AGCCTCACAT TCCTGTCCCA CAATGATGTG 
AAACTGTTGT GTGATGTCTT GAACCAGGCA GAGTGCAACA TAGAAAAGCT GATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030098620.1
CDS	1..2217
Translation	MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIADVVDFFSLVLTDSGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLM

Target ORF information:

RefSeq Version	XM_030242760.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus NLR family, pyrin domain containing 4E (Nlrp4e), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030242760.1

ORF Insert Sequence:

ATGGCATCAT TTTTTTCTGA TTTTGGCCTT ATGTGGTACT TGGAAGAGCT AAACAAGAAA 
GAATTCATGA AATTTAAGGA ATTACTCCAA CAGGAGATTT TGCAGTTGGG GCTGAAACAC 
ATTTCTTGGA CCGAAGTGAA GAAGGCATCT CGTGAAGACC TTGCCAACTT ACTGTTGAAA 
CATTATGAGG AGAAGAAAGC CTGGGATATG ACCTTCAAAA TCTTCCAGAA GATGAATAGG 
CAGGATCTCA TGGAGAGGGC AGGAAGAGAG ATTGCTGATG TTGTGGATTT TTTTTCCCTT 
GTGCTCACTG ACTCAGGACA CTCAAAGTTA TATCAAGTTC ATTTGAAGAA GAAGCTGACC 
CATGATTATG CCAGAAAGTT TAACATCAAA GATCAAGATT CCCTTAAGCA GAAATTTACC 
CAGGATGACT GTGATCATTT TGAGAACCTT CTCATATCAA AGGCGACTGG AAAGAAGCCA 
CACATGGTGT TTCTGCAAGG AGTGGCGGGA ATTGGCAAGT CACTGATGTT GACAAAGTTA 
ATGCTTGCCT GGTCAGAAGG CATGGTGTTT CAGAACAAAT TCTCCTACAT CTTCTACTTC 
TGCTGTCAAG ATGTGAAGAA GATGAAGAGA GCAAGCCTGG CAGAATTGAT CTCCAAAGAG 
TGGCCCAACG CCTCAGCTCC CATAGAGGAG ATCCTGTCCC AACCGGAGAA ACTCTTATTT 
GTCATCGACA ACTTGGAAGT GATGGAATGT GATATGTCTG AATGGGAGTC GGAGCTGTGT 
GATGACTGCA TGGAGAAGCA GCCAGTGAAT ATACTGATGA GCAGTTTGCT CAGGAGGAAG 
ATGCTCCCTG AATCCTCTTT CCTCGTCTCT GCTACCCCAG AGACTTTTGA GAAAATAGAG 
GACAGGATTG AGTGCACAAA TGTAAAAATG ATGGCAGGAT TCAATGAGAG CAGTATTAAG 
GTGTATTTCT ACAGCTTGTT CCAAGATAGG AACAGAACCC AGGAAATTTT CAGTTTGGTG 
AGAGAAAATG AGCAGCTGTT CTCTGTATGT CAAGTCCCTG TGCTCTGCTG GATGGTGGCT 
ACTTGTCTAA AAAAAGAGAT AGAGAAGGGA AGAGACCCAG TCTCAATCTG CCGACGTATC 
ACTTCCCTGT ATACCACTTA CATCTTCAAT TTGTTCATTC CCCACAGTGC CCAATATCCA 
AGTAAGAAAA GCCAAGACCA GCTGCAGGGC TTATGTTCTC TGGCTGCTGA GGGCATGTGG 
ACTGACACAT TTGTGTTTGC TGAGGAGGCT CTCAGGAGAA ATGGGATCAT GGACTCTGAT 
ATCTCCACAC TGCTGGACGT AAGGATCCTT GAAAAGAGCA AGGAATCTGA AAAATCTTAC 
ATTTTCCTCC ACCCATCTAT CCAGGAGGTC TGTGCTGCCA TCTTTCATCT GCTAAAGAGC 
CATGTAGACC ATCCTAGCCA GGATGTCAAA AGTATAGAGG CACTCATATT TACATTTCTA 
AAGAAAGTCA AAATACAGTG GATTTTTTTT GGCTCTTTCA TCTTTGGCCT TTTACATGAA 
TCAGAACAAA AAAAGCTAGA GGCATTTTTT GGCCACCAGT TGTCCCAAGA AATAAAACGT 
CAGTTGTATC AGTGCCTGGA AACCATAAGT GGCAATAAAG AGCTTCAAGA ACAGATAGAT 
GGCATGAAGC TGTTTTACTG TCTGTTTGAG ATGGACGATG AAGCCTTCTT ACCACAAGTT 
ATGAACTGTA TGGAACAGAT TAAATTTGTG GCTAAGGATT ATTCTGATGT TATTGTTGCT 
GCCCACTGCT TACAACACTG TTCTACACTG AAAAAACTAT CCTTGTCAAC CCAGAATATC 
CTGAGTGAAG GTCAAGAACA CAGCTATACG GAAAAGCTAC TCATCTGTTG GCATCATGTG 
TGCTCTGTGC TCACAAGCAG TAAGGATATC CACGTACTCC AAGTGAAAGA CACTAATTTC 
AATGAAAGAG CCTTTTTGGT CTTGTATAGT CATCTGAAGT ACCCCAGCTG CATCCTTAAA 
GTACTTGAGG TAAATAATGT GACTTTGCTT TGTGATAACC GCCTGTTATT TGAGTTGATT 
CAGAACCAAC GTTTGCAGCT CTTGAACCTC AGCCTCACAT TCCTGTCCCA CAATGATGTG 
AAACTGTTGT GTGATGTCTT GAACCAGGCA GAGTGCAACA TAGAAAAGCT GATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome.
Molecular cell64(2)267-281(2016 10)
Lin M,Zhao Z,Yang Z,Meng Q,Tan P,Xie W,Qin Y,Wang RF,Cui J

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Developmental expression and possible functional roles of mouse Nlrp4e in preimplantation embryos.
In vitro cellular & developmental biology. Animal49(7)548-53(2013 Aug)
Chang BH,Liu X,Liu J,Quan FS,Guo ZK,Zhang Y

Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice.
Mediators of inflammation2013751374(2013)
DeSantis DA,Ko CW,Liu Y,Liu X,Hise AG,Nunez G,Croniger CM

Age-associated alteration of gene expression patterns in mouse oocytes.
Human molecular genetics13(19)2263-78(2004 Oct)
Hamatani T,Falco G,Carter MG,Akutsu H,Stagg CA,Sharov AA,Dudekula DB,VanBuren V,Ko MS

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Nlrp4e cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM