Dock1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dock1
Entrez Gene ID	330662
Full Name	dedicator of cytokinesis 1
Synonyms	9130006G06Rik,AI854900,D630004B07Rik,b2b3190Clo
General protein information	Preferred Names dedicator of cytokinesis 1 Names dedicator of cytokinesis protein 1 180 kDa protein downstream of CRK DOCK180 dedicator of cyto-kinesis 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033420.2	NP_001028592.1	dedicator of cytokinesis protein 1
XM_006507965.3	XP_006508028.1	dedicator of cytokinesis protein 1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dock1	NP_001028592.1
Danio rerio (zebrafish)	dock1	NP_001103481.1
Bos taurus (cattle)	DOCK1	XP_005225929.1
Rattus norvegicus (Norway rat)	Dock1	NP_001137330.1
Caenorhabditis elegans (roundworm)	ced-5	NP_501938.1
Homo sapiens (human)	DOCK1	NP_001371.1
Canis lupus familiaris (dog)	DOCK1	XP_544064.4
Drosophila melanogaster (fruit fly)	mbc	NP_001247267.1
Xenopus tropicalis (tropical clawed frog)	dock1	XP_002932708.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004320	XP_313591.5
Gallus gallus (chicken)	DOCK1	XP_421819.4

Gene Ontology
Bibliography

Related articles in PubMed

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.
Tajiri H, Uruno T, Shirai T, Takaya D, Matsunaga S, Setoyama D, Watanabe M, Kukimoto-Niino M, Oisaki K, Ushijima M, Sanematsu F, Honma T, Terada T, Oki E, Shirasawa S, Maehara Y, Kang D, Côté JF, Yokoyama S, Kanai M, Fukui Y
Cell reports19(5)969-980(2017 05)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling.
Bagci H, Laurin M, Huber J, Muller WJ, Côté JF
Cell death & disease5e1375(2014 Aug)

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.
Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU
Experimental eye research121130-42(2014 Apr)

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.
Laurin M, Dumouchel A, Fukui Y, Côté JF
Small GTPases4(4)221-30(2013 Oct-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dock1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dock1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21588	NM_001033420.2 Latest version!	Mus musculus dedicator of cytokinesis 1 (Dock1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00
OMu39730	XM_006507965.3 Latest version!	Mus musculus dedicator of cytokinesis 1 (Dock1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dock1 ( NM_001033420.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028592.1 Mus musculus dedicator of cytokinesis 1 (Dock1), mRNA.

Price & Availability↑

CloneID	OMu21588
Clone ID Related Accession (Same CDS sequence)	NM_001033420.2
Accession Version	NM_001033420.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1562169600000
Organism	Mus musculus(house mouse)
Product	dedicator of cytokinesis protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129300.3, AC100208.16, AC127574.3, AC136515.3 and AC136641.3. On Nov 17, 2006 this sequence version replaced NM_001033420.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC 
GATGCCAGGG GAGCAGATGA ACTGTCCCTT CAAATTGGAG ACACCGTGCA CATCCTAGAA 
ACTTATGAAG GGTGGTACAG AGGCTACACC TTAAGGAAAA AGTCTAAAAA GGGTATATTT 
CCTGCTTCAT ATATTCATCT TAAAGAAGCC ATTGTTGAAG GAAAAGGGCA ACATGAAACC 
GTCATCCCTG GGGACCTCCC CCTTATACAG GAAGTCACCA CAACGCTTCG AGAGTGGTCT 
ACCATCTGGA GGCAACTTTA TGTGCAAGAT AATAGAGAGA TGTTTCGAAG TGTGCGACAC 
ATGATCTATG ACCTTATTGA ATGGCGGTCG CAGATCCTTT CTGGAACTCT GCCCCAGGAT 
GAGCTCAAAG AGCTGAAGAA GAAGGTCACA GCCAAAATTG ATTATGGAAA CAGAATTCTT 
GATTTGGACC TGGTGGTGAG GGATGAAGAT GGGAACATTT TGGACCCGGA ACTAACTAGC 
ACCATCAGTC TCTTCCGAGC ACACGAAGTT GCTTCTAAAC AAGTGGAGGA GAGACTGCAA 
GAGGAGAAAT CTCAAAAGCA GAACATGGAT ATCAACAGAC AAGCCAAGTT TGCAGCCACC 
CCATCGCTGG CCTTGTTTGT TAACCTCAAA AATGTGGTTT GTAAAATAGG AGAAGATGCT 
GAAGTTCTCA TGTCTCTTTA TGACCCCATG GAGTCCAAAT TCATCAGTGA GAACTATCTG 
GTCCGCTGGT CAAGTTCAGG ATTACCAAAA GATATTGATC GGTTACATAA CTTGCGAGCT 
GTGTTTACGG ATCTGGGGAG CAAAGACTTG AAAAGGGAGA AAATTAGTTT CGTCTGCCAG 
ATTGTCCGTG TCGGTCGCAT GGAGCTGAGG GACAGCAACA CGAGGAAGCT GACTTCGGGG 
CTGCGGCGAC CTTTCGGCGT GGCTGTGATG GATGTGACAG ACATAATAAA CGGGAAAGTC 
GATGATGAAG ATAAACAGCA TTTCATCCCC TTCCAGGCGG TGGCAGGGGA GAATGACTTC 
CTTCAAACTG TCATAAACAA AGTCATTGCA GCCAAAGAAG TCAACCACAA GGGACAAGGT 
TTGTGGGTAA CCTTGAAATT ACTTCCTGGA GACATCCATC AGATTCGGAA GGAGTTTCCT 
CACTTGGTGG ACAGGACCAC AGCTGTGGCC CGCAAGACAG GGTTTCCTGA GATTATTATG 
CCAGGTGATG TTCGAAATGA TATCTATGTG ACATTAGTTC AAGGGGATTT TGATAAAGGC 
AGTAAAACAA CTGCGAAGAA CGTGGAGGTG ACAGTGTCTG TCTATGATGA AGATGGGAAG 
CGATTGGAGC ACGTGATTTT CCCCGGTGCT GGCGACGAGG CGATCTCCGA GTACAAATCG 
GTGATTTATT ATCAAGTGAA GCAGCCTCGC TGGTTTGAGA CCCTTAAGGT GGCCATCCCC 
ATTGAGGACG TGAACCGGAG TCACCTTCGA TTCACCTTCC GCCATAGATC CTCGCAGGAC 
TCCAAGGATA AATCTGAAAA GATCTTCGCA CTGGCCTTTG TGAAGCTGAT GAGATACGAT 
GGGACCACCC TGAGAGACGG GGAGCATGAC CTTATTGTCT ACAAGGCTGA AGCCAAAAAG 
CTCGAAGATG CAGCCACATA CTTGAGCCTC CCTAGTACCA AGGGGGAGTT GGAAGAAAAG 
GGCCACTCAG CCACAGGCAA AGGAATGCAG AGTCTTGGGA GTTGTACCAT CAGCAAAGAC 
TCTTTCCAGA TCTCCACTCT GGTGTGTTCC ACGAAACTGA CCCAGAACGT GGACCTCCTG 
GGGCTGTTGA AGTGGAGATC CAACACCAAC CTTCTGCAGC AGAACTTGAG GCAGTTGATG 
AAGGTGGACG GTGGTGAAGT GGTGAAGTTC CTTCAGGACA CCTTGGATGC CCTCTTCAAC 
ATCATGATGG AGAACTCAGA GAGTGAGACG TTTGATACCT TGGTGTTTGA TGCTCTGGTC 
TTTATTATTG GACTAATCGC GGATAGGAAA TTTCAGCATT TTAATCCTGT TTTGGAGACT 
TACATTAAGA AACACTTCAG TGCAACATTA GCCTACACGA AGCTGACCAA GGTGTTACGG 
ACCTACGTGG CCAGCGCAGA GAAGCCGGGA GTCAACGAGC AGCTGTACAA AGCCATAAAA 
GCCTTGGAGT ACATCTTCAA GTTCATAGTG CGCTCACGGG TACTGTTCAA CCAGCTGTAT 
GAAAACAAGG GGGAAGCTGA CTTCGTGGAG TCCTTGTTGC AGCTGTTCCG GTCCATCAAC 
GACATGATGA GCAGCCTGTC AGAGCTCACA GTCAGGGTGA AGGGGGCAGC CCTGAAGTAC 
TTGCCGACGA TCGTCAATGA TGTGAAGTTG GTGTTTGATC CCAAGGAGCT CAGCAAAATG 
TTCACGGAAT TCATCCTGAA TGTCCCTGCG GGCTTGCTGA CGGTCCAGAA GCTCTCCTGC 
CTGATTGAGA TTGTTCACAG TGACCTCTTC ACACAGCATG ACTGCAGAGA GATCCTGCTC 
CCCATGATGA CAGACCAGCT CAAGTACCAC CTGGAGAGGC AGGAGGAGCT GGAGGCTTGT 
TGCCAGCTGC TTAGCAACAT CCTGGAGGTG CTATACCGGA AGGATGTGGG ACCGACTCAG 
AGGCACGTCC AGATCATCAT GGAGACGCTG CTTAGGACTG TGAACAGGAC GGTCATTTCC 
ATGGGGCGGG ACTCCGAGCT CATTGGGAAC TTTGTGGCTT GCATGACAGC CATTTTACGG 
CAGATGGAAG ACTACCATTA TGCACACCTG ATCAAGACCT TTGGGAAAAT GAGGACAGAT 
GTCGTGGATT TTCTGATGGA GACATTCATC ATGTTTAAGA ACCTCATCGG GAAGAACGTC 
TACCCCTTCG ACTGGGTGAT AATGAACACG ATGCAGAACA AAGTCTTTCT GCGGGCGATT 
AATCAGTATG CAGATATGCT GAACAAGAGA TTTCTGGATC AAGCCAACTT TGAGCTGCAG 
CTGTGGAACA ACTACTTTCA CCTGGCCGTG GCTTTCCTCA CTCAAGAGTC CCTGCAACTG 
GAGAATTTTT CAAGTGCTAA GAGAGCTAAA ATCCTTAACA AGTATGGAGA CATGAGGAGG 
CAGATTGGCT TTGAGATCAG AGACATGTGG TACAACCTGG GTCAACACAA GATAAAATTC 
ATCCCAGAAA TGGTTGGCCC AATATTGGAA ATGACATTGA TTCCTGAGAC AGAGCTTCGA 
AAAGCCACCC TTCCCATCTT CTTCGACATG ATGCAGTGTG AATTCCACTC CACCCGGAGC 
TTTCAAATGT TTGAAAATGA GATCATCACT AAGCTGGATC ATGAAGTGGA AGGAGGCAGA 
GGAGACGAGC AATACAAAGT GTTATTTGAT AAAATCCTCC TGGAGCACTG CAGGAAGCAT 
AAATACCTCG CCAAGACAGG AGAAACTTTT GTGAAGCTCG TAGTGCGGTT GATGGAGAGG 
CTCCTGGACT ACAGGACCAT CATGCATGAC GAAAACAAAG ACAATCGGAT GAGCTGCACC 
GTCAACGTGC TGAATTTCTA CAAAGAAATT GAAAGAGAAG AGATGTATAT AAGGTACTTG 
TATAAGCTCT GTGACCTGCA CAAAGAGTGT GACAACTACA CAGAGGCGGC CTACACTTTG 
CTTCTGCACG CGAAACTTCT AAAGTGGTCA GAGGACGTGT GTGCAGCTCA CCTCACTCAG 
CGGGACGGGT TCCAGGCGAC AACACAGGGA CAGCTGAAAG AGCAGCTCTA CCAAGAAATC 
ATCCACTACT TTGACAAAGG CAAGATGTGG GAGGAGGCCA TCGCCCTGGG CAAGGAACTT 
GCGGAGCAGT ACGAAACAGA GATGTTTGAT TATGAGCAGC TCAGTGAATT GCTGAAAAAA 
CAGGCACAAT TTTACGAGAA CATCGTGAAG GTGATAAGAC CCAAGCCTGA CTATTTTGCT 
GTTGGCTACT ATGGGCAAGG GTTCCCGTCA TTCCTTCGGG GCAAAGTGTT CATTTACCGA 
GGCAAGGAAT ATGAGCGACG GGAAGATTTT GAAGCTCGGC TGTTAACTCA GTTTCCAAAT 
GCTGAAAAAA TGAAGACGAC GTCTCCACCG GGCGATGACA TTAAGACTTC TCCCGGCCAG 
TACATCCAGT GCTTCACAGT GAAGCCCAAG CTAGACTTAC CTCCGAGATT TCACCGACCC 
GTGTCTGAAC AGATTGTAAG TTTTTACAGG GTGAATGAGG TACAGCGATT CGAGTATTCA 
CGGCCCATCC GGAAAGGAGA GAAAAACCCA GACAATGAAT TTGCGAATAT GTGGATTGAA 
AGAACCATCT ACACTACGGC CTATAAACTG CCAGGAATTT TAAGGTGGTT TGAAGTCAAA 
TCTGTCTTCA TGGTAGAGAT CAGCCCACTG GAGAATGCCA TCGAGACAAT GCAGTTGACC 
AATGACAAGA TCAGCAGCAT GGTCCAGCAG CACCTGGATG ACCCGGGCCT GCCTATCAAC 
CCCCTGTCCA TGCTCCTGAA TGGCATTGTG GATCCTGCTG TCATGGGTGG TTTTGCCAAT 
TATGAGAAGG CTTTCTTCAC AGACAGATAC CTGCAGGAGC ATCCTGAGGC CCATGGGCAG 
ATTGAGAAGC TCAAGGACCT GATAGCCTGG CAGATTCCAT TTTTGGCTGA AGGGATCAGG 
ATTCATGGAG ACAAAGTCAC AGAGGCCCTG AGGCCATTCC ACGAGCGCAT GGAAGCCTGC 
TTCAAGCAAC TGAAGGAAAA AGTGGAAAAG CAATATGGCG TCAGGACCAT GCCCTCAGGC 
TTGGATGACA GGAGAGGCAG CCGTCCACGT TCAATGGTGC GATCTTTCAC CATGCCATCA 
TCCTCCCGGC CCCTGTCAGT GGCTTCCGTC TCTTCTTTCT CCTCTGACAG CACTCCTTCC 
AGGCCAGGCT CTGATGGATT TGCTCTAGAG CCTCTGCTGC CGAAGAAGAT GCACTCCAGG 
TCCCAGGACA AGCTAGACAA GGACGATCCA GATAAAGAGA AGAAGGACAA GAAGAAGGAG 
AAAAGGAACA GCAAACACCA AGAGATATTT GATAAGGAAT TCAAGCCCGC TGACAGCTCC 
CTGCAGCAGT CTGAGGCTGT GATCCTTTCT GAAACGATAA GTCCCCTGCG GCCCCAAAGA 
CCCAAGAGCC AGGTGATCAA TGTCATTGGA AATGAAAGGC GCTTCTCTGT GTCTCCAGCA 
TCACCGTCCT CCCAGCAGAC GCCCCCTCCA GTCACACCAA GAGCCAAGCT CAGCTTCAGC 
ATTCAGCCCA GTCTGGAGCT GAACGGCATG ATGGGAATGG ATGTGGCCGA TGTCCCACCC 
CCTCTGCCCC TCAAAGGCAA CATGGCAGAT TATGGAAATC TGATGGAAAA CCAGGATATG 
ATGGTCTCAC CCACATCTCC ACCTCCTCCT CCCCCACAAC GGCAACAGCC ACCTCCACTG 
CCCAGCAAAA CACCACCTCC TCCCCCTCCG AAGACGACCC GAAAGCAGAC CTCAGTGGAC 
TCTGGAATCG TGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028592.1
CDS	113..5710
Translation	MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEVASKQVEERLQEEKSQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPMESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDSNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQAVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETLKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKGELEEKGHSATGKGMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTNLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRTYVASAEKPGVNEQLYKAIKALEYIFKFIVRSRVLFNQLYENKGEADFVESLLQLFRSINDMMSSLSELTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPAGLLTVQKLSCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEELEACCQLLSNILEVLYRKDVGPTQRHVQIIMETLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNTMQNKVFLRAINQYADMLNKRFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKDNRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCAAHLTQRDGFQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYETEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPSFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKTSPGQYIQCFTVKPKLDLPPRFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKISSMVQQHLDDPGLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHGQIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGVRTMPSGLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSFSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDPDKEKKDKKKEKRNSKHQEIFDKEFKPADSSLQQSEAVILSETISPLRPQRPKSQVINVIGNERRFSVSPASPSSQQTPPPVTPRAKLSFSIQPSLELNGMMGMDVADVPPPLPLKGNMADYGNLMENQDMMVSPTSPPPPPPQRQQPPPLPSKTPPPPPPKTTRKQTSVDSGIVQ

Target ORF information:

RefSeq Version	NM_001033420.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dedicator of cytokinesis 1 (Dock1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033420.2

ORF Insert Sequence:

ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC 
GATGCCAGGG GAGCAGATGA ACTGTCCCTT CAAATTGGAG ACACCGTGCA CATCCTAGAA 
ACTTATGAAG GGTGGTACAG AGGCTACACC TTAAGGAAAA AGTCTAAAAA GGGTATATTT 
CCTGCTTCAT ATATTCATCT TAAAGAAGCC ATTGTTGAAG GAAAAGGGCA ACATGAAACC 
GTCATCCCTG GGGACCTCCC CCTTATACAG GAAGTCACCA CAACGCTTCG AGAGTGGTCT 
ACCATCTGGA GGCAACTTTA TGTGCAAGAT AATAGAGAGA TGTTTCGAAG TGTGCGACAC 
ATGATCTATG ACCTTATTGA ATGGCGGTCG CAGATCCTTT CTGGAACTCT GCCCCAGGAT 
GAGCTCAAAG AGCTGAAGAA GAAGGTCACA GCCAAAATTG ATTATGGAAA CAGAATTCTT 
GATTTGGACC TGGTGGTGAG GGATGAAGAT GGGAACATTT TGGACCCGGA ACTAACTAGC 
ACCATCAGTC TCTTCCGAGC ACACGAAGTT GCTTCTAAAC AAGTGGAGGA GAGACTGCAA 
GAGGAGAAAT CTCAAAAGCA GAACATGGAT ATCAACAGAC AAGCCAAGTT TGCAGCCACC 
CCATCGCTGG CCTTGTTTGT TAACCTCAAA AATGTGGTTT GTAAAATAGG AGAAGATGCT 
GAAGTTCTCA TGTCTCTTTA TGACCCCATG GAGTCCAAAT TCATCAGTGA GAACTATCTG 
GTCCGCTGGT CAAGTTCAGG ATTACCAAAA GATATTGATC GGTTACATAA CTTGCGAGCT 
GTGTTTACGG ATCTGGGGAG CAAAGACTTG AAAAGGGAGA AAATTAGTTT CGTCTGCCAG 
ATTGTCCGTG TCGGTCGCAT GGAGCTGAGG GACAGCAACA CGAGGAAGCT GACTTCGGGG 
CTGCGGCGAC CTTTCGGCGT GGCTGTGATG GATGTGACAG ACATAATAAA CGGGAAAGTC 
GATGATGAAG ATAAACAGCA TTTCATCCCC TTCCAGGCGG TGGCAGGGGA GAATGACTTC 
CTTCAAACTG TCATAAACAA AGTCATTGCA GCCAAAGAAG TCAACCACAA GGGACAAGGT 
TTGTGGGTAA CCTTGAAATT ACTTCCTGGA GACATCCATC AGATTCGGAA GGAGTTTCCT 
CACTTGGTGG ACAGGACCAC AGCTGTGGCC CGCAAGACAG GGTTTCCTGA GATTATTATG 
CCAGGTGATG TTCGAAATGA TATCTATGTG ACATTAGTTC AAGGGGATTT TGATAAAGGC 
AGTAAAACAA CTGCGAAGAA CGTGGAGGTG ACAGTGTCTG TCTATGATGA AGATGGGAAG 
CGATTGGAGC ACGTGATTTT CCCCGGTGCT GGCGACGAGG CGATCTCCGA GTACAAATCG 
GTGATTTATT ATCAAGTGAA GCAGCCTCGC TGGTTTGAGA CCCTTAAGGT GGCCATCCCC 
ATTGAGGACG TGAACCGGAG TCACCTTCGA TTCACCTTCC GCCATAGATC CTCGCAGGAC 
TCCAAGGATA AATCTGAAAA GATCTTCGCA CTGGCCTTTG TGAAGCTGAT GAGATACGAT 
GGGACCACCC TGAGAGACGG GGAGCATGAC CTTATTGTCT ACAAGGCTGA AGCCAAAAAG 
CTCGAAGATG CAGCCACATA CTTGAGCCTC CCTAGTACCA AGGGGGAGTT GGAAGAAAAG 
GGCCACTCAG CCACAGGCAA AGGAATGCAG AGTCTTGGGA GTTGTACCAT CAGCAAAGAC 
TCTTTCCAGA TCTCCACTCT GGTGTGTTCC ACGAAACTGA CCCAGAACGT GGACCTCCTG 
GGGCTGTTGA AGTGGAGATC CAACACCAAC CTTCTGCAGC AGAACTTGAG GCAGTTGATG 
AAGGTGGACG GTGGTGAAGT GGTGAAGTTC CTTCAGGACA CCTTGGATGC CCTCTTCAAC 
ATCATGATGG AGAACTCAGA GAGTGAGACG TTTGATACCT TGGTGTTTGA TGCTCTGGTC 
TTTATTATTG GACTAATCGC GGATAGGAAA TTTCAGCATT TTAATCCTGT TTTGGAGACT 
TACATTAAGA AACACTTCAG TGCAACATTA GCCTACACGA AGCTGACCAA GGTGTTACGG 
ACCTACGTGG CCAGCGCAGA GAAGCCGGGA GTCAACGAGC AGCTGTACAA AGCCATAAAA 
GCCTTGGAGT ACATCTTCAA GTTCATAGTG CGCTCACGGG TACTGTTCAA CCAGCTGTAT 
GAAAACAAGG GGGAAGCTGA CTTCGTGGAG TCCTTGTTGC AGCTGTTCCG GTCCATCAAC 
GACATGATGA GCAGCCTGTC AGAGCTCACA GTCAGGGTGA AGGGGGCAGC CCTGAAGTAC 
TTGCCGACGA TCGTCAATGA TGTGAAGTTG GTGTTTGATC CCAAGGAGCT CAGCAAAATG 
TTCACGGAAT TCATCCTGAA TGTCCCTGCG GGCTTGCTGA CGGTCCAGAA GCTCTCCTGC 
CTGATTGAGA TTGTTCACAG TGACCTCTTC ACACAGCATG ACTGCAGAGA GATCCTGCTC 
CCCATGATGA CAGACCAGCT CAAGTACCAC CTGGAGAGGC AGGAGGAGCT GGAGGCTTGT 
TGCCAGCTGC TTAGCAACAT CCTGGAGGTG CTATACCGGA AGGATGTGGG ACCGACTCAG 
AGGCACGTCC AGATCATCAT GGAGACGCTG CTTAGGACTG TGAACAGGAC GGTCATTTCC 
ATGGGGCGGG ACTCCGAGCT CATTGGGAAC TTTGTGGCTT GCATGACAGC CATTTTACGG 
CAGATGGAAG ACTACCATTA TGCACACCTG ATCAAGACCT TTGGGAAAAT GAGGACAGAT 
GTCGTGGATT TTCTGATGGA GACATTCATC ATGTTTAAGA ACCTCATCGG GAAGAACGTC 
TACCCCTTCG ACTGGGTGAT AATGAACACG ATGCAGAACA AAGTCTTTCT GCGGGCGATT 
AATCAGTATG CAGATATGCT GAACAAGAGA TTTCTGGATC AAGCCAACTT TGAGCTGCAG 
CTGTGGAACA ACTACTTTCA CCTGGCCGTG GCTTTCCTCA CTCAAGAGTC CCTGCAACTG 
GAGAATTTTT CAAGTGCTAA GAGAGCTAAA ATCCTTAACA AGTATGGAGA CATGAGGAGG 
CAGATTGGCT TTGAGATCAG AGACATGTGG TACAACCTGG GTCAACACAA GATAAAATTC 
ATCCCAGAAA TGGTTGGCCC AATATTGGAA ATGACATTGA TTCCTGAGAC AGAGCTTCGA 
AAAGCCACCC TTCCCATCTT CTTCGACATG ATGCAGTGTG AATTCCACTC CACCCGGAGC 
TTTCAAATGT TTGAAAATGA GATCATCACT AAGCTGGATC ATGAAGTGGA AGGAGGCAGA 
GGAGACGAGC AATACAAAGT GTTATTTGAT AAAATCCTCC TGGAGCACTG CAGGAAGCAT 
AAATACCTCG CCAAGACAGG AGAAACTTTT GTGAAGCTCG TAGTGCGGTT GATGGAGAGG 
CTCCTGGACT ACAGGACCAT CATGCATGAC GAAAACAAAG ACAATCGGAT GAGCTGCACC 
GTCAACGTGC TGAATTTCTA CAAAGAAATT GAAAGAGAAG AGATGTATAT AAGGTACTTG 
TATAAGCTCT GTGACCTGCA CAAAGAGTGT GACAACTACA CAGAGGCGGC CTACACTTTG 
CTTCTGCACG CGAAACTTCT AAAGTGGTCA GAGGACGTGT GTGCAGCTCA CCTCACTCAG 
CGGGACGGGT TCCAGGCGAC AACACAGGGA CAGCTGAAAG AGCAGCTCTA CCAAGAAATC 
ATCCACTACT TTGACAAAGG CAAGATGTGG GAGGAGGCCA TCGCCCTGGG CAAGGAACTT 
GCGGAGCAGT ACGAAACAGA GATGTTTGAT TATGAGCAGC TCAGTGAATT GCTGAAAAAA 
CAGGCACAAT TTTACGAGAA CATCGTGAAG GTGATAAGAC CCAAGCCTGA CTATTTTGCT 
GTTGGCTACT ATGGGCAAGG GTTCCCGTCA TTCCTTCGGG GCAAAGTGTT CATTTACCGA 
GGCAAGGAAT ATGAGCGACG GGAAGATTTT GAAGCTCGGC TGTTAACTCA GTTTCCAAAT 
GCTGAAAAAA TGAAGACGAC GTCTCCACCG GGCGATGACA TTAAGACTTC TCCCGGCCAG 
TACATCCAGT GCTTCACAGT GAAGCCCAAG CTAGACTTAC CTCCGAGATT TCACCGACCC 
GTGTCTGAAC AGATTGTAAG TTTTTACAGG GTGAATGAGG TACAGCGATT CGAGTATTCA 
CGGCCCATCC GGAAAGGAGA GAAAAACCCA GACAATGAAT TTGCGAATAT GTGGATTGAA 
AGAACCATCT ACACTACGGC CTATAAACTG CCAGGAATTT TAAGGTGGTT TGAAGTCAAA 
TCTGTCTTCA TGGTAGAGAT CAGCCCACTG GAGAATGCCA TCGAGACAAT GCAGTTGACC 
AATGACAAGA TCAGCAGCAT GGTCCAGCAG CACCTGGATG ACCCGGGCCT GCCTATCAAC 
CCCCTGTCCA TGCTCCTGAA TGGCATTGTG GATCCTGCTG TCATGGGTGG TTTTGCCAAT 
TATGAGAAGG CTTTCTTCAC AGACAGATAC CTGCAGGAGC ATCCTGAGGC CCATGGGCAG 
ATTGAGAAGC TCAAGGACCT GATAGCCTGG CAGATTCCAT TTTTGGCTGA AGGGATCAGG 
ATTCATGGAG ACAAAGTCAC AGAGGCCCTG AGGCCATTCC ACGAGCGCAT GGAAGCCTGC 
TTCAAGCAAC TGAAGGAAAA AGTGGAAAAG CAATATGGCG TCAGGACCAT GCCCTCAGGC 
TTGGATGACA GGAGAGGCAG CCGTCCACGT TCAATGGTGC GATCTTTCAC CATGCCATCA 
TCCTCCCGGC CCCTGTCAGT GGCTTCCGTC TCTTCTTTCT CCTCTGACAG CACTCCTTCC 
AGGCCAGGCT CTGATGGATT TGCTCTAGAG CCTCTGCTGC CGAAGAAGAT GCACTCCAGG 
TCCCAGGACA AGCTAGACAA GGACGATCCA GATAAAGAGA AGAAGGACAA GAAGAAGGAG 
AAAAGGAACA GCAAACACCA AGAGATATTT GATAAGGAAT TCAAGCCCGC TGACAGCTCC 
CTGCAGCAGT CTGAGGCTGT GATCCTTTCT GAAACGATAA GTCCCCTGCG GCCCCAAAGA 
CCCAAGAGCC AGGTGATCAA TGTCATTGGA AATGAAAGGC GCTTCTCTGT GTCTCCAGCA 
TCACCGTCCT CCCAGCAGAC GCCCCCTCCA GTCACACCAA GAGCCAAGCT CAGCTTCAGC 
ATTCAGCCCA GTCTGGAGCT GAACGGCATG ATGGGAATGG ATGTGGCCGA TGTCCCACCC 
CCTCTGCCCC TCAAAGGCAA CATGGCAGAT TATGGAAATC TGATGGAAAA CCAGGATATG 
ATGGTCTCAC CCACATCTCC ACCTCCTCCT CCCCCACAAC GGCAACAGCC ACCTCCACTG 
CCCAGCAAAA CACCACCTCC TCCCCCTCCG AAGACGACCC GAAAGCAGAC CTCAGTGGAC 
TCTGGAATCG TGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dock1 ( XM_006507965.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508028.1 Mus musculus dedicator of cytokinesis 1 (Dock1), transcript variant X1, mRNA.

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CloneID	OMu39730
Clone ID Related Accession (Same CDS sequence)	XM_006507965.3
Accession Version	XM_006507965.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5661bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	dedicator of cytokinesis protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507965.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC 
GATGCCAGGG GAGCAGATGA ACTGTCCCTT CAAATTGGAG ACACCGTGCA CATCCTAGAA 
ACTTATGAAG GGTGGTACAG AGGCTACACC TTAAGGAAAA AGTCTAAAAA GGGTATATTT 
CCTGCTTCAT ATATTCATCT TAAAGAAGCC ATTGTTGAAG GAAAAGGGCA ACATGAAACC 
GTCATCCCTG GGGACCTCCC CCTTATACAG GAAGTCACCA CAACGCTTCG AGAGTGGTCT 
ACCATCTGGA GGCAACTTTA TGTGCAAGAT AATAGAGAGA TGTTTCGAAG TGTGCGACAC 
ATGATCTATG ACCTTATTGA ATGGCGGTCG CAGATCCTTT CTGGAACTCT GCCCCAGGAT 
GAGCTCAAAG AGCTGAAGAA GAAGGTCACA GCCAAAATTG ATTATGGAAA CAGAATTCTT 
GATTTGGACC TGGTGGTGAG GGATGAAGAT GGGAACATTT TGGACCCGGA ACTAACTAGC 
ACCATCAGTC TCTTCCGAGC ACACGAAGTT GCTTCTAAAC AAGTGGAGGA GAGACTGCAA 
GAGGAGAAAT CTCAAAAGCA GAACATGGAT ATCAACAGAC AAGCCAAGTT TGCAGCCACC 
CCATCGCTGG CCTTGTTTGT TAACCTCAAA AATGTGGTTT GTAAAATAGG AGAAGATGCT 
GAAGTTCTCA TGTCTCTTTA TGACCCCATG GAGTCCAAAT TCATCAGTGA GAACTATCTG 
GTCCGCTGGT CAAGTTCAGG ATTACCAAAA GATATTGATC GGTTACATAA CTTGCGAGCT 
GTGTTTACGG ATCTGGGGAG CAAAGACTTG AAAAGGGAGA AAATTAGTTT CGTCTGCCAG 
ATTGTCCGTG TCGGTCGCAT GGAGCTGAGG GACAGCAACA CGAGGAAGCT GACTTCGGGG 
CTGCGGCGAC CTTTCGGCGT GGCTGTGATG GATGTGACAG ACATAATAAA CGGGAAAGTC 
GATGATGAAG ATAAACAGCA TTTCATCCCC TTCCAGGCGC TCGCGTTGGA CGACGCCATT 
CGACACAAGC CGCTGAACAT GTCATCCCGT TTCTCACCCA GGGTGGCAGG GGAGAATGAC 
TTCCTTCAAA CTGTCATAAA CAAAGTCATT GCAGCCAAAG AAGTCAACCA CAAGGGACAA 
GGTTTGTGGG TAACCTTGAA ATTACTTCCT GGAGACATCC ATCAGATTCG GAAGGAGTTT 
CCTCACTTGG TGGACAGGAC CACAGCTGTG GCCCGCAAGA CAGGGTTTCC TGAGATTATT 
ATGCCAGGTG ATGTTCGAAA TGATATCTAT GTGACATTAG TTCAAGGGGA TTTTGATAAA 
GGCAGTAAAA CAACTGCGAA GAACGTGGAG GTGACAGTGT CTGTCTATGA TGAAGATGGG 
AAGCGATTGG AGCACGTGAT TTTCCCCGGT GCTGGCGACG AGGCGATCTC CGAGTACAAA 
TCGGTGATTT ATTATCAAGT GAAGCAGCCT CGCTGGTTTG AGACCCTTAA GGTGGCCATC 
CCCATTGAGG ACGTGAACCG GAGTCACCTT CGATTCACCT TCCGCCATAG ATCCTCGCAG 
GACTCCAAGG ATAAATCTGA AAAGATCTTC GCACTGGCCT TTGTGAAGCT GATGAGATAC 
GATGGGACCA CCCTGAGAGA CGGGGAGCAT GACCTTATTG TCTACAAGGC TGAAGCCAAA 
AAGCTCGAAG ATGCAGCCAC ATACTTGAGC CTCCCTAGTA CCAAGGGGGA GTTGGAAGAA 
AAGGGCCACT CAGCCACAGG CAAAGGAATG CAGAGTCTTG GGAGTTGTAC CATCAGCAAA 
GACTCTTTCC AGATCTCCAC TCTGGTGTGT TCCACGAAAC TGACCCAGAA CGTGGACCTC 
CTGGGGCTGT TGAAGTGGAG ATCCAACACC AACCTTCTGC AGCAGAACTT GAGGCAGTTG 
ATGAAGGTGG ACGGTGGTGA AGTGGTGAAG TTCCTTCAGG ACACCTTGGA TGCCCTCTTC 
AACATCATGA TGGAGAACTC AGAGAGTGAG ACGTTTGATA CCTTGGTGTT TGATGCTCTG 
GTCTTTATTA TTGGACTAAT CGCGGATAGG AAATTTCAGC ATTTTAATCC TGTTTTGGAG 
ACTTACATTA AGAAACACTT CAGTGCAACA TTAGCCTACA CGAAGCTGAC CAAGGTGTTA 
CGGACCTACG TGGCCAGCGC AGAGAAGCCG GGAGTCAACG AGCAGCTGTA CAAAGCCATA 
AAAGCCTTGG AGTACATCTT CAAGTTCATA GTGCGCTCAC GGGTACTGTT CAACCAGCTG 
TATGAAAACA AGGGGGAAGC TGACTTCGTG GAGTCCTTGT TGCAGCTGTT CCGGTCCATC 
AACGACATGA TGAGCAGCCT GTCAGAGCTC ACAGTCAGGG TGAAGGGGGC AGCCCTGAAG 
TACTTGCCGA CGATCGTCAA TGATGTGAAG TTGGTGTTTG ATCCCAAGGA GCTCAGCAAA 
ATGTTCACGG AATTCATCCT GAATGTCCCT GCGGGCTTGC TGACGGTCCA GAAGCTCTCC 
TGCCTGATTG AGATTGTTCA CAGTGACCTC TTCACACAGC ATGACTGCAG AGAGATCCTG 
CTCCCCATGA TGACAGACCA GCTCAAGTAC CACCTGGAGA GGCAGGAGGA GCTGGAGGCT 
TGTTGCCAGC TGCTTAGCAA CATCCTGGAG GTGCTATACC GGAAGGATGT GGGACCGACT 
CAGAGGCACG TCCAGATCAT CATGGAGACG CTGCTTAGGA CTGTGAACAG GACGGTCATT 
TCCATGGGGC GGGACTCCGA GCTCATTGGG AACTTTGTGG CTTGCATGAC AGCCATTTTA 
CGGCAGATGG AAGACTACCA TTATGCACAC CTGATCAAGA CCTTTGGGAA AATGAGGACA 
GATGTCGTGG ATTTTCTGAT GGAGACATTC ATCATGTTTA AGAACCTCAT CGGGAAGAAC 
GTCTACCCCT TCGACTGGGT GATAATGAAC ACGATGCAGA ACAAAGTCTT TCTGCGGGCG 
ATTAATCAGT ATGCAGATAT GCTGAACAAG AGATTTCTGG ATCAAGCCAA CTTTGAGCTG 
CAGCTGTGGA ACAACTACTT TCACCTGGCC GTGGCTTTCC TCACTCAAGA GTCCCTGCAA 
CTGGAGAATT TTTCAAGTGC TAAGAGAGCT AAAATCCTTA ACAAGTATGG AGACATGAGG 
AGGCAGATTG GCTTTGAGAT CAGAGACATG TGGTACAACC TGGGTCAACA CAAGATAAAA 
TTCATCCCAG AAATGGTTGG CCCAATATTG GAAATGACAT TGATTCCTGA GACAGAGCTT 
CGAAAAGCCA CCCTTCCCAT CTTCTTCGAC ATGATGCAGT GTGAATTCCA CTCCACCCGG 
AGCTTTCAAA TGTTTGAAAA TGAGATCATC ACTAAGCTGG ATCATGAAGT GGAAGGAGGC 
AGAGGAGACG AGCAATACAA AGTGTTATTT GATAAAATCC TCCTGGAGCA CTGCAGGAAG 
CATAAATACC TCGCCAAGAC AGGAGAAACT TTTGTGAAGC TCGTAGTGCG GTTGATGGAG 
AGGCTCCTGG ACTACAGGAC CATCATGCAT GACGAAAACA AAGACAATCG GATGAGCTGC 
ACCGTCAACG TGCTGAATTT CTACAAAGAA ATTGAAAGAG AAGAGATGTA TATAAGGTAC 
TTGTATAAGC TCTGTGACCT GCACAAAGAG TGTGACAACT ACACAGAGGC GGCCTACACT 
TTGCTTCTGC ACGCGAAACT TCTAAAGTGG TCAGAGGACG TGTGTGCAGC TCACCTCACT 
CAGCGGGACG GGTTCCAGGC GACAACACAG GGACAGCTGA AAGAGCAGCT CTACCAAGAA 
ATCATCCACT ACTTTGACAA AGGCAAGATG TGGGAGGAGG CCATCGCCCT GGGCAAGGAA 
CTTGCGGAGC AGTACGAAAC AGAGATGTTT GATTATGAGC AGCTCAGTGA ATTGCTGAAA 
AAACAGGCAC AATTTTACGA GAACATCGTG AAGGTGATAA GACCCAAGCC TGACTATTTT 
GCTGTTGGCT ACTATGGGCA AGGGTTCCCG TCATTCCTTC GGGGCAAAGT GTTCATTTAC 
CGAGGCAAGG AATATGAGCG ACGGGAAGAT TTTGAAGCTC GGCTGTTAAC TCAGTTTCCA 
AATGCTGAAA AAATGAAGAC GACGTCTCCA CCGGGCGATG ACATTAAGAC TTCTCCCGGC 
CAGTACATCC AGTGCTTCAC AGTGAAGCCC AAGCTAGACT TACCTCCGAG ATTTCACCGA 
CCCGTGTCTG AACAGATTGT AAGTTTTTAC AGGGTGAATG AGGTACAGCG ATTCGAGTAT 
TCACGGCCCA TCCGGAAAGG AGAGAAAAAC CCAGACAATG AATTTGCGAA TATGTGGATT 
GAAAGAACCA TCTACACTAC GGCCTATAAA CTGCCAGGAA TTTTAAGGTG GTTTGAAGTC 
AAATCTGTCT TCATGGTAGA GATCAGCCCA CTGGAGAATG CCATCGAGAC AATGCAGTTG 
ACCAATGACA AGATCAGCAG CATGGTCCAG CAGCACCTGG ATGACCCGGG CCTGCCTATC 
AACCCCCTGT CCATGCTCCT GAATGGCATT GTGGATCCTG CTGTCATGGG TGGTTTTGCC 
AATTATGAGA AGGCTTTCTT CACAGACAGA TACCTGCAGG AGCATCCTGA GGCCCATGGG 
CAGATTGAGA AGCTCAAGGA CCTGATAGCC TGGCAGATTC CATTTTTGGC TGAAGGGATC 
AGGATTCATG GAGACAAAGT CACAGAGGCC CTGAGGCCAT TCCACGAGCG CATGGAAGCC 
TGCTTCAAGC AACTGAAGGA AAAAGTGGAA AAGCAATATG GCGTCAGGAC CATGCCCTCA 
GGCTTGGATG ACAGGAGAGG CAGCCGTCCA CGTTCAATGG TGCGATCTTT CACCATGCCA 
TCATCCTCCC GGCCCCTGTC AGTGGCTTCC GTCTCTTCTT TCTCCTCTGA CAGCACTCCT 
TCCAGGCCAG GCTCTGATGG ATTTGCTCTA GAGCCTCTGC TGCCGAAGAA GATGCACTCC 
AGGTCCCAGG ACAAGCTAGA CAAGGACGAT CCAGATAAAG AGAAGAAGGA CAAGAAGAAG 
GAGAAAAGGA ACAGCAAACA CCAAGAGATA TTTGATAAGG AATTCAAGCC CGCTGACAGC 
TCCCTGCAGC AGTCTGAGGC TGTGATCCTT TCTGAAACGA TAAGTCCCCT GCGGCCCCAA 
AGACCCAAGA GCCAGGTGAT CAATGTCATT GGAAATGAAA GGCGCTTCTC TGTGTCTCCA 
GCATCACCGT CCTCCCAGCA GACGCCCCCT CCAGTCACAC CAAGAGCCAA GCTCAGCTTC 
AGCATTCAGC CCAGTCTGGA GCTGAACGGC ATGATGGGAA TGGATGTGGC CGATGTCCCA 
CCCCCTCTGC CCCTCAAAGG CAACATGGCA GATTATGGAA ATCTGATGGA AAACCAGGAT 
ATGATGGTCT CACCCACATC TCCACCTCCT CCTCCCCCAC AACGGCAACA GCCACCTCCA 
CTGCCCAGCA AAACACCACC TCCTCCCCCT CCGAAGACGA CCCGAAAGCA GACCTCAGTG 
GACTCTGGAA TCGTGCAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508028.1
CDS	195..5855
Translation	MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEVASKQVEERLQEEKSQKQNMDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPMESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDSNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQALALDDAIRHKPLNMSSRFSPRVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETLKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKGELEEKGHSATGKGMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTNLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLRTYVASAEKPGVNEQLYKAIKALEYIFKFIVRSRVLFNQLYENKGEADFVESLLQLFRSINDMMSSLSELTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPAGLLTVQKLSCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEELEACCQLLSNILEVLYRKDVGPTQRHVQIIMETLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNTMQNKVFLRAINQYADMLNKRFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATLPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKDNRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCAAHLTQRDGFQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYETEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPSFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKTSPGQYIQCFTVKPKLDLPPRFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKISSMVQQHLDDPGLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHGQIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKQYGVRTMPSGLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSFSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDPDKEKKDKKKEKRNSKHQEIFDKEFKPADSSLQQSEAVILSETISPLRPQRPKSQVINVIGNERRFSVSPASPSSQQTPPPVTPRAKLSFSIQPSLELNGMMGMDVADVPPPLPLKGNMADYGNLMENQDMMVSPTSPPPPPPQRQQPPPLPSKTPPPPPPKTTRKQTSVDSGIVQ

Target ORF information:

RefSeq Version	XM_006507965.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dedicator of cytokinesis 1 (Dock1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006507965.3

ORF Insert Sequence:

ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC 
GATGCCAGGG GAGCAGATGA ACTGTCCCTT CAAATTGGAG ACACCGTGCA CATCCTAGAA 
ACTTATGAAG GGTGGTACAG AGGCTACACC TTAAGGAAAA AGTCTAAAAA GGGTATATTT 
CCTGCTTCAT ATATTCATCT TAAAGAAGCC ATTGTTGAAG GAAAAGGGCA ACATGAAACC 
GTCATCCCTG GGGACCTCCC CCTTATACAG GAAGTCACCA CAACGCTTCG AGAGTGGTCT 
ACCATCTGGA GGCAACTTTA TGTGCAAGAT AATAGAGAGA TGTTTCGAAG TGTGCGACAC 
ATGATCTATG ACCTTATTGA ATGGCGGTCG CAGATCCTTT CTGGAACTCT GCCCCAGGAT 
GAGCTCAAAG AGCTGAAGAA GAAGGTCACA GCCAAAATTG ATTATGGAAA CAGAATTCTT 
GATTTGGACC TGGTGGTGAG GGATGAAGAT GGGAACATTT TGGACCCGGA ACTAACTAGC 
ACCATCAGTC TCTTCCGAGC ACACGAAGTT GCTTCTAAAC AAGTGGAGGA GAGACTGCAA 
GAGGAGAAAT CTCAAAAGCA GAACATGGAT ATCAACAGAC AAGCCAAGTT TGCAGCCACC 
CCATCGCTGG CCTTGTTTGT TAACCTCAAA AATGTGGTTT GTAAAATAGG AGAAGATGCT 
GAAGTTCTCA TGTCTCTTTA TGACCCCATG GAGTCCAAAT TCATCAGTGA GAACTATCTG 
GTCCGCTGGT CAAGTTCAGG ATTACCAAAA GATATTGATC GGTTACATAA CTTGCGAGCT 
GTGTTTACGG ATCTGGGGAG CAAAGACTTG AAAAGGGAGA AAATTAGTTT CGTCTGCCAG 
ATTGTCCGTG TCGGTCGCAT GGAGCTGAGG GACAGCAACA CGAGGAAGCT GACTTCGGGG 
CTGCGGCGAC CTTTCGGCGT GGCTGTGATG GATGTGACAG ACATAATAAA CGGGAAAGTC 
GATGATGAAG ATAAACAGCA TTTCATCCCC TTCCAGGCGC TCGCGTTGGA CGACGCCATT 
CGACACAAGC CGCTGAACAT GTCATCCCGT TTCTCACCCA GGGTGGCAGG GGAGAATGAC 
TTCCTTCAAA CTGTCATAAA CAAAGTCATT GCAGCCAAAG AAGTCAACCA CAAGGGACAA 
GGTTTGTGGG TAACCTTGAA ATTACTTCCT GGAGACATCC ATCAGATTCG GAAGGAGTTT 
CCTCACTTGG TGGACAGGAC CACAGCTGTG GCCCGCAAGA CAGGGTTTCC TGAGATTATT 
ATGCCAGGTG ATGTTCGAAA TGATATCTAT GTGACATTAG TTCAAGGGGA TTTTGATAAA 
GGCAGTAAAA CAACTGCGAA GAACGTGGAG GTGACAGTGT CTGTCTATGA TGAAGATGGG 
AAGCGATTGG AGCACGTGAT TTTCCCCGGT GCTGGCGACG AGGCGATCTC CGAGTACAAA 
TCGGTGATTT ATTATCAAGT GAAGCAGCCT CGCTGGTTTG AGACCCTTAA GGTGGCCATC 
CCCATTGAGG ACGTGAACCG GAGTCACCTT CGATTCACCT TCCGCCATAG ATCCTCGCAG 
GACTCCAAGG ATAAATCTGA AAAGATCTTC GCACTGGCCT TTGTGAAGCT GATGAGATAC 
GATGGGACCA CCCTGAGAGA CGGGGAGCAT GACCTTATTG TCTACAAGGC TGAAGCCAAA 
AAGCTCGAAG ATGCAGCCAC ATACTTGAGC CTCCCTAGTA CCAAGGGGGA GTTGGAAGAA 
AAGGGCCACT CAGCCACAGG CAAAGGAATG CAGAGTCTTG GGAGTTGTAC CATCAGCAAA 
GACTCTTTCC AGATCTCCAC TCTGGTGTGT TCCACGAAAC TGACCCAGAA CGTGGACCTC 
CTGGGGCTGT TGAAGTGGAG ATCCAACACC AACCTTCTGC AGCAGAACTT GAGGCAGTTG 
ATGAAGGTGG ACGGTGGTGA AGTGGTGAAG TTCCTTCAGG ACACCTTGGA TGCCCTCTTC 
AACATCATGA TGGAGAACTC AGAGAGTGAG ACGTTTGATA CCTTGGTGTT TGATGCTCTG 
GTCTTTATTA TTGGACTAAT CGCGGATAGG AAATTTCAGC ATTTTAATCC TGTTTTGGAG 
ACTTACATTA AGAAACACTT CAGTGCAACA TTAGCCTACA CGAAGCTGAC CAAGGTGTTA 
CGGACCTACG TGGCCAGCGC AGAGAAGCCG GGAGTCAACG AGCAGCTGTA CAAAGCCATA 
AAAGCCTTGG AGTACATCTT CAAGTTCATA GTGCGCTCAC GGGTACTGTT CAACCAGCTG 
TATGAAAACA AGGGGGAAGC TGACTTCGTG GAGTCCTTGT TGCAGCTGTT CCGGTCCATC 
AACGACATGA TGAGCAGCCT GTCAGAGCTC ACAGTCAGGG TGAAGGGGGC AGCCCTGAAG 
TACTTGCCGA CGATCGTCAA TGATGTGAAG TTGGTGTTTG ATCCCAAGGA GCTCAGCAAA 
ATGTTCACGG AATTCATCCT GAATGTCCCT GCGGGCTTGC TGACGGTCCA GAAGCTCTCC 
TGCCTGATTG AGATTGTTCA CAGTGACCTC TTCACACAGC ATGACTGCAG AGAGATCCTG 
CTCCCCATGA TGACAGACCA GCTCAAGTAC CACCTGGAGA GGCAGGAGGA GCTGGAGGCT 
TGTTGCCAGC TGCTTAGCAA CATCCTGGAG GTGCTATACC GGAAGGATGT GGGACCGACT 
CAGAGGCACG TCCAGATCAT CATGGAGACG CTGCTTAGGA CTGTGAACAG GACGGTCATT 
TCCATGGGGC GGGACTCCGA GCTCATTGGG AACTTTGTGG CTTGCATGAC AGCCATTTTA 
CGGCAGATGG AAGACTACCA TTATGCACAC CTGATCAAGA CCTTTGGGAA AATGAGGACA 
GATGTCGTGG ATTTTCTGAT GGAGACATTC ATCATGTTTA AGAACCTCAT CGGGAAGAAC 
GTCTACCCCT TCGACTGGGT GATAATGAAC ACGATGCAGA ACAAAGTCTT TCTGCGGGCG 
ATTAATCAGT ATGCAGATAT GCTGAACAAG AGATTTCTGG ATCAAGCCAA CTTTGAGCTG 
CAGCTGTGGA ACAACTACTT TCACCTGGCC GTGGCTTTCC TCACTCAAGA GTCCCTGCAA 
CTGGAGAATT TTTCAAGTGC TAAGAGAGCT AAAATCCTTA ACAAGTATGG AGACATGAGG 
AGGCAGATTG GCTTTGAGAT CAGAGACATG TGGTACAACC TGGGTCAACA CAAGATAAAA 
TTCATCCCAG AAATGGTTGG CCCAATATTG GAAATGACAT TGATTCCTGA GACAGAGCTT 
CGAAAAGCCA CCCTTCCCAT CTTCTTCGAC ATGATGCAGT GTGAATTCCA CTCCACCCGG 
AGCTTTCAAA TGTTTGAAAA TGAGATCATC ACTAAGCTGG ATCATGAAGT GGAAGGAGGC 
AGAGGAGACG AGCAATACAA AGTGTTATTT GATAAAATCC TCCTGGAGCA CTGCAGGAAG 
CATAAATACC TCGCCAAGAC AGGAGAAACT TTTGTGAAGC TCGTAGTGCG GTTGATGGAG 
AGGCTCCTGG ACTACAGGAC CATCATGCAT GACGAAAACA AAGACAATCG GATGAGCTGC 
ACCGTCAACG TGCTGAATTT CTACAAAGAA ATTGAAAGAG AAGAGATGTA TATAAGGTAC 
TTGTATAAGC TCTGTGACCT GCACAAAGAG TGTGACAACT ACACAGAGGC GGCCTACACT 
TTGCTTCTGC ACGCGAAACT TCTAAAGTGG TCAGAGGACG TGTGTGCAGC TCACCTCACT 
CAGCGGGACG GGTTCCAGGC GACAACACAG GGACAGCTGA AAGAGCAGCT CTACCAAGAA 
ATCATCCACT ACTTTGACAA AGGCAAGATG TGGGAGGAGG CCATCGCCCT GGGCAAGGAA 
CTTGCGGAGC AGTACGAAAC AGAGATGTTT GATTATGAGC AGCTCAGTGA ATTGCTGAAA 
AAACAGGCAC AATTTTACGA GAACATCGTG AAGGTGATAA GACCCAAGCC TGACTATTTT 
GCTGTTGGCT ACTATGGGCA AGGGTTCCCG TCATTCCTTC GGGGCAAAGT GTTCATTTAC 
CGAGGCAAGG AATATGAGCG ACGGGAAGAT TTTGAAGCTC GGCTGTTAAC TCAGTTTCCA 
AATGCTGAAA AAATGAAGAC GACGTCTCCA CCGGGCGATG ACATTAAGAC TTCTCCCGGC 
CAGTACATCC AGTGCTTCAC AGTGAAGCCC AAGCTAGACT TACCTCCGAG ATTTCACCGA 
CCCGTGTCTG AACAGATTGT AAGTTTTTAC AGGGTGAATG AGGTACAGCG ATTCGAGTAT 
TCACGGCCCA TCCGGAAAGG AGAGAAAAAC CCAGACAATG AATTTGCGAA TATGTGGATT 
GAAAGAACCA TCTACACTAC GGCCTATAAA CTGCCAGGAA TTTTAAGGTG GTTTGAAGTC 
AAATCTGTCT TCATGGTAGA GATCAGCCCA CTGGAGAATG CCATCGAGAC AATGCAGTTG 
ACCAATGACA AGATCAGCAG CATGGTCCAG CAGCACCTGG ATGACCCGGG CCTGCCTATC 
AACCCCCTGT CCATGCTCCT GAATGGCATT GTGGATCCTG CTGTCATGGG TGGTTTTGCC 
AATTATGAGA AGGCTTTCTT CACAGACAGA TACCTGCAGG AGCATCCTGA GGCCCATGGG 
CAGATTGAGA AGCTCAAGGA CCTGATAGCC TGGCAGATTC CATTTTTGGC TGAAGGGATC 
AGGATTCATG GAGACAAAGT CACAGAGGCC CTGAGGCCAT TCCACGAGCG CATGGAAGCC 
TGCTTCAAGC AACTGAAGGA AAAAGTGGAA AAGCAATATG GCGTCAGGAC CATGCCCTCA 
GGCTTGGATG ACAGGAGAGG CAGCCGTCCA CGTTCAATGG TGCGATCTTT CACCATGCCA 
TCATCCTCCC GGCCCCTGTC AGTGGCTTCC GTCTCTTCTT TCTCCTCTGA CAGCACTCCT 
TCCAGGCCAG GCTCTGATGG ATTTGCTCTA GAGCCTCTGC TGCCGAAGAA GATGCACTCC 
AGGTCCCAGG ACAAGCTAGA CAAGGACGAT CCAGATAAAG AGAAGAAGGA CAAGAAGAAG 
GAGAAAAGGA ACAGCAAACA CCAAGAGATA TTTGATAAGG AATTCAAGCC CGCTGACAGC 
TCCCTGCAGC AGTCTGAGGC TGTGATCCTT TCTGAAACGA TAAGTCCCCT GCGGCCCCAA 
AGACCCAAGA GCCAGGTGAT CAATGTCATT GGAAATGAAA GGCGCTTCTC TGTGTCTCCA 
GCATCACCGT CCTCCCAGCA GACGCCCCCT CCAGTCACAC CAAGAGCCAA GCTCAGCTTC 
AGCATTCAGC CCAGTCTGGA GCTGAACGGC ATGATGGGAA TGGATGTGGC CGATGTCCCA 
CCCCCTCTGC CCCTCAAAGG CAACATGGCA GATTATGGAA ATCTGATGGA AAACCAGGAT 
ATGATGGTCT CACCCACATC TCCACCTCCT CCTCCCCCAC AACGGCAACA GCCACCTCCA 
CTGCCCAGCA AAACACCACC TCCTCCCCCT CCGAAGACGA CCCGAAAGCA GACCTCAGTG 
GACTCTGGAA TCGTGCAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.
Cell reports19(5)969-980(2017 05)
Tajiri H,Uruno T,Shirai T,Takaya D,Matsunaga S,Setoyama D,Watanabe M,Kukimoto-Niino M,Oisaki K,Ushijima M,Sanematsu F,Honma T,Terada T,Oki E,Shirasawa S,Maehara Y,Kang D,Côté JF,Yokoyama S,Kanai M,Fukui Y

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling.
Cell death & disease5e1375(2014 Aug)
Bagci H,Laurin M,Huber J,Muller WJ,Côté JF

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.
Experimental eye research121130-42(2014 Apr)
Teo ZL,McQueen-Miscamble L,Turner K,Martinez G,Madakashira B,Dedhar S,Robinson ML,de Iongh RU

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.
Small GTPases4(4)221-30(2013 Oct-Dec)
Laurin M,Dumouchel A,Fukui Y,Côté JF

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Dock1 cDNA ORF clone, Mus musculus(house mouse)

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