Msrb3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Msrb3
Entrez Gene ID	320183
Full Name	methionine sulfoxide reductase B3
Synonyms	D430026P16Rik,I-8-23,MsrB2
General protein information	Preferred Names methionine sulfoxide reductase B3 Names methionine-R-sulfoxide reductase B3, mitochondrial
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_177092.4	NP_796066.1	methionine-R-sulfoxide reductase B3, mitochondrial
XM_006513766.3	XP_006513829.1	methionine-R-sulfoxide reductase B3, mitochondrial isoform X3
XM_006513763.3	XP_006513826.1	methionine-R-sulfoxide reductase B3, mitochondrial isoform X1
XM_006513764.3	XP_006513827.1	methionine-R-sulfoxide reductase B3, mitochondrial isoform X2
XM_006513764.4	XP_006513827.1	methionine-R-sulfoxide reductase B3, mitochondrial isoform X1
XM_006513766.4	XP_006513829.1	methionine-R-sulfoxide reductase B3, mitochondrial isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	MSRB3	NP_001026849.1
Pan troglodytes (chimpanzee)	MSRB3	XP_001163219.1
Bos taurus (cattle)	MSRB3	XP_002687589.1
Macaca mulatta (Rhesus monkey)	MSRB3	XP_001117006.1
Mus musculus (house mouse)	Msrb3	NP_796066.1
Danio rerio (zebrafish)	msrb3	NP_001002094.1
Canis lupus familiaris (dog)	MSRB3	XP_850508.3
Rattus norvegicus (Norway rat)	Msrb3	XP_006241476.1
Arabidopsis thaliana (thale cress)	MSRB1	NP_564640.2
Gallus gallus (chicken)	MSRB3	NP_001186507.1
Drosophila melanogaster (fruit fly)	SelR	NP_731522.1

Gene Ontology
Bibliography

Related articles in PubMed

Methionine sulfoxide reductase B3 deficiency stimulates heme oxygenase-1 expression via ROS-dependent and Nrf2 activation pathways.
Kwak GH, Kim KY, Kim HY
Biochemical and biophysical research communications473(4)1033-1038(2016 05)

Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.
Kim MA, Cho HJ, Bae SH, Lee B, Oh SK, Kwon TJ, Ryoo ZY, Kim HY, Cho JH, Kim UK, Lee KY
Antioxidants & redox signaling24(11)590-602(2016 Apr)

Methionine sulfoxide reductase B3 deficiency inhibits cell growth through the activation of p53-p21 and p27 pathways.
Lee E, Kwak GH, Kamble K, Kim HY
Archives of biochemistry and biophysics5471-5(2014 Apr)

Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.
Kwon TJ, Cho HJ, Kim UK, Lee E, Oh SK, Bok J, Bae YC, Yi JK, Lee JW, Ryoo ZY, Lee SH, Lee KY, Kim HY
Human molecular genetics23(6)1591-601(2014 Mar)

Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase.
Kim HY, Gladyshev VN
Biochemical and biophysical research communications320(4)1277-83(2004 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Msrb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Msrb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu44574	XM_006513763.3 Latest version!	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu44575	XM_006513764.4 Latest version!	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu44576	XM_006513766.4 Latest version!	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu13133	NM_177092.4 Latest version!	Mus musculus methionine sulfoxide reductase B3 (Msrb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OMu44575	XM_006513764.3	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu44576	XM_006513766.3	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Msrb3 ( XM_006513763.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513826.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44574
Clone ID Related Accession (Same CDS sequence)	XM_006513763.3
Accession Version	XM_006513763.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513763.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCCAG GGGGCTCTGC TACGGGTTGC CCACGCGCGG AAGCCCTGTT CCCGCAGGGC 
TGGCCCGGGG CGGTGGAGGC GGCGCCGGAG GCGGGAGTTG GCGGCGGCCG CGTCCCGGGC 
AGCGGGCCCC GTCCGCGGCC AGCGCGCTCC GCCGTCCTCC CTCGCTTGTC TGCTATGCTC 
ATATTTGGAC TCGGCCGCCC GTGCCCAGGA ATTTCCCGTC ATGCCTCCCG CCGCCCCGTC 
TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG AGGCTCGTCT TCCCCAAGAG 
TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG GGTCTCTGCC TAGCCGCGGC 
CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC TCTGCTGGAG ATACCACAGC 
TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC CAGCCCGTGG CCCCGAGAGC 
CTGCGGGCTC CCCTCAGGTC AGAAACCAAA TTTGACTCTG GTTCAGGCTG GCCTGCCTTC 
CATGATGTGA TCAGTTCGGA GGCCATCGAG TTCACAGATG ACTTTTCCTA CGGGATGCAC 
AGGGTGGAAA CCAGCTGTTC TCAGTGTGGT GCTCATCTCG GGCACATTTT TGACGATGGA 
CCTCGTCCGA CCGGCAAAAG ATACTGCATC AACTCAGCAT CCTTGTCCTT CACTCCTGCA 
GACAGCAGTG AGGCAGAAGG AAGCGGCATC AAAGAGAGCG GCAGCCCAGC AGCAGCAGAC 
AGAGCTGAGC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513826.1
CDS	4..798
Translation	MLPGGSATGCPRAEALFPQGWPGAVEAAPEAGVGGGRVPGSGPRPRPARSAVLPRLSAMLIFGLGRPCPGISRHASRRPVCRPEPGGRRDRTAEARLPQECAADPPVPNRALPGSLPSRGRGHHDARFCRCLCLCWRYHSYVCLQPAALGDEEPARGPESLRAPLRSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	XM_006513763.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513763.3

ORF Insert Sequence:

ATGCTGCCAG GGGGCTCTGC TACGGGTTGC CCACGCGCGG AAGCCCTGTT CCCGCAGGGC 
TGGCCCGGGG CGGTGGAGGC GGCGCCGGAG GCGGGAGTTG GCGGCGGCCG CGTCCCGGGC 
AGCGGGCCCC GTCCGCGGCC AGCGCGCTCC GCCGTCCTCC CTCGCTTGTC TGCTATGCTC 
ATATTTGGAC TCGGCCGCCC GTGCCCAGGA ATTTCCCGTC ATGCCTCCCG CCGCCCCGTC 
TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG AGGCTCGTCT TCCCCAAGAG 
TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG GGTCTCTGCC TAGCCGCGGC 
CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC TCTGCTGGAG ATACCACAGC 
TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC CAGCCCGTGG CCCCGAGAGC 
CTGCGGGCTC CCCTCAGGTC AGAAACCAAA TTTGACTCTG GTTCAGGCTG GCCTGCCTTC 
CATGATGTGA TCAGTTCGGA GGCCATCGAG TTCACAGATG ACTTTTCCTA CGGGATGCAC 
AGGGTGGAAA CCAGCTGTTC TCAGTGTGGT GCTCATCTCG GGCACATTTT TGACGATGGA 
CCTCGTCCGA CCGGCAAAAG ATACTGCATC AACTCAGCAT CCTTGTCCTT CACTCCTGCA 
GACAGCAGTG AGGCAGAAGG AAGCGGCATC AAAGAGAGCG GCAGCCCAGC AGCAGCAGAC 
AGAGCTGAGC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msrb3 ( XM_006513764.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513827.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu44575
Clone ID Related Accession (Same CDS sequence)	XM_006513764.3 , XM_006513764.4
Accession Version	XM_006513764.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513764.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGGT CATGTAGGGA TAAAAAGAAC 
TGTAAGGTGG TCTTTTCCCA GCAGGAACTG AGGAAGCGGC TGACACCCCT ACAGTACCAT 
GTCACTCAGG AGAAAGGAAC TGAAAGTGCC TTTGAAGGAG AGTACACACA TCACAAAGAT 
CCTGGAATAT ATAAATGTGT TGTCTGTGGA ACTCCGTTGT TCAAGTCAGA AACCAAATTT 
GACTCTGGTT CAGGCTGGCC TGCCTTCCAT GATGTGATCA GTTCGGAGGC CATCGAGTTC 
ACAGATGACT TTTCCTACGG GATGCACAGG GTGGAAACCA GCTGTTCTCA GTGTGGTGCT 
CATCTCGGGC ACATTTTTGA CGATGGACCT CGTCCGACCG GCAAAAGATA CTGCATCAAC 
TCAGCATCCT TGTCCTTCAC TCCTGCAGAC AGCAGTGAGG CAGAAGGAAG CGGCATCAAA 
GAGAGCGGCA GCCCAGCAGC AGCAGACAGA GCTGAGCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513827.1
CDS	84..845
Translation	MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	XM_006513764.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513764.3

ORF Insert Sequence:

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGGT CATGTAGGGA TAAAAAGAAC 
TGTAAGGTGG TCTTTTCCCA GCAGGAACTG AGGAAGCGGC TGACACCCCT ACAGTACCAT 
GTCACTCAGG AGAAAGGAAC TGAAAGTGCC TTTGAAGGAG AGTACACACA TCACAAAGAT 
CCTGGAATAT ATAAATGTGT TGTCTGTGGA ACTCCGTTGT TCAAGTCAGA AACCAAATTT 
GACTCTGGTT CAGGCTGGCC TGCCTTCCAT GATGTGATCA GTTCGGAGGC CATCGAGTTC 
ACAGATGACT TTTCCTACGG GATGCACAGG GTGGAAACCA GCTGTTCTCA GTGTGGTGCT 
CATCTCGGGC ACATTTTTGA CGATGGACCT CGTCCGACCG GCAAAAGATA CTGCATCAAC 
TCAGCATCCT TGTCCTTCAC TCCTGCAGAC AGCAGTGAGG CAGAAGGAAG CGGCATCAAA 
GAGAGCGGCA GCCCAGCAGC AGCAGACAGA GCTGAGCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msrb3 ( XM_006513764.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513827.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44575
Clone ID Related Accession (Same CDS sequence)	XM_006513764.3 , XM_006513764.4
Accession Version	XM_006513764.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006513764.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGGT CATGTAGGGA TAAAAAGAAC 
TGTAAGGTGG TCTTTTCCCA GCAGGAACTG AGGAAGCGGC TGACACCCCT ACAGTACCAT 
GTCACTCAGG AGAAAGGAAC TGAAAGTGCC TTTGAAGGAG AGTACACACA TCACAAAGAT 
CCTGGAATAT ATAAATGTGT TGTCTGTGGA ACTCCGTTGT TCAAGTCAGA AACCAAATTT 
GACTCTGGTT CAGGCTGGCC TGCCTTCCAT GATGTGATCA GTTCGGAGGC CATCGAGTTC 
ACAGATGACT TTTCCTACGG GATGCACAGG GTGGAAACCA GCTGTTCTCA GTGTGGTGCT 
CATCTCGGGC ACATTTTTGA CGATGGACCT CGTCCGACCG GCAAAAGATA CTGCATCAAC 
TCAGCATCCT TGTCCTTCAC TCCTGCAGAC AGCAGTGAGG CAGAAGGAAG CGGCATCAAA 
GAGAGCGGCA GCCCAGCAGC AGCAGACAGA GCTGAGCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513827.1
CDS	116..877
Translation	MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	XM_006513764.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513764.4

ORF Insert Sequence:

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGGT CATGTAGGGA TAAAAAGAAC 
TGTAAGGTGG TCTTTTCCCA GCAGGAACTG AGGAAGCGGC TGACACCCCT ACAGTACCAT 
GTCACTCAGG AGAAAGGAAC TGAAAGTGCC TTTGAAGGAG AGTACACACA TCACAAAGAT 
CCTGGAATAT ATAAATGTGT TGTCTGTGGA ACTCCGTTGT TCAAGTCAGA AACCAAATTT 
GACTCTGGTT CAGGCTGGCC TGCCTTCCAT GATGTGATCA GTTCGGAGGC CATCGAGTTC 
ACAGATGACT TTTCCTACGG GATGCACAGG GTGGAAACCA GCTGTTCTCA GTGTGGTGCT 
CATCTCGGGC ACATTTTTGA CGATGGACCT CGTCCGACCG GCAAAAGATA CTGCATCAAC 
TCAGCATCCT TGTCCTTCAC TCCTGCAGAC AGCAGTGAGG CAGAAGGAAG CGGCATCAAA 
GAGAGCGGCA GCCCAGCAGC AGCAGACAGA GCTGAGCTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msrb3 ( XM_006513766.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513829.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu44576
Clone ID Related Accession (Same CDS sequence)	XM_006513766.3 , XM_006513766.4
Accession Version	XM_006513766.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513766.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGCT GGCCTGCCTT CCATGATGTG 
ATCAGTTCGG AGGCCATCGA GTTCACAGAT GACTTTTCCT ACGGGATGCA CAGGGTGGAA 
ACCAGCTGTT CTCAGTGTGG TGCTCATCTC GGGCACATTT TTGACGATGG ACCTCGTCCG 
ACCGGCAAAA GATACTGCAT CAACTCAGCA TCCTTGTCCT TCACTCCTGC AGACAGCAGT 
GAGGCAGAAG GAAGCGGCAT CAAAGAGAGC GGCAGCCCAG CAGCAGCAGA CAGAGCTGAG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513829.1
CDS	84..629
Translation	MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	XM_006513766.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513766.3

ORF Insert Sequence:

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGCT GGCCTGCCTT CCATGATGTG 
ATCAGTTCGG AGGCCATCGA GTTCACAGAT GACTTTTCCT ACGGGATGCA CAGGGTGGAA 
ACCAGCTGTT CTCAGTGTGG TGCTCATCTC GGGCACATTT TTGACGATGG ACCTCGTCCG 
ACCGGCAAAA GATACTGCAT CAACTCAGCA TCCTTGTCCT TCACTCCTGC AGACAGCAGT 
GAGGCAGAAG GAAGCGGCAT CAAAGAGAGC GGCAGCCCAG CAGCAGCAGA CAGAGCTGAG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msrb3 ( XM_006513766.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513829.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu44576
Clone ID Related Accession (Same CDS sequence)	XM_006513766.3 , XM_006513766.4
Accession Version	XM_006513766.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006513766.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGCT GGCCTGCCTT CCATGATGTG 
ATCAGTTCGG AGGCCATCGA GTTCACAGAT GACTTTTCCT ACGGGATGCA CAGGGTGGAA 
ACCAGCTGTT CTCAGTGTGG TGCTCATCTC GGGCACATTT TTGACGATGG ACCTCGTCCG 
ACCGGCAAAA GATACTGCAT CAACTCAGCA TCCTTGTCCT TCACTCCTGC AGACAGCAGT 
GAGGCAGAAG GAAGCGGCAT CAAAGAGAGC GGCAGCCCAG CAGCAGCAGA CAGAGCTGAG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513829.1
CDS	20..565
Translation	MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	XM_006513766.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513766.4

ORF Insert Sequence:

ATGCCTCCCG CCGCCCCGTC TGTCGCCCGG AGCCGGGAGG GAGGAGGGAT CGGACAGCGG 
AGGCTCGTCT TCCCCAAGAG TGCGCGGCGG ACCCTCCCGT GCCCAATCGC GCTCTGCCTG 
GGTCTCTGCC TAGCCGCGGC CGCGGCCACC ACGACGCGCG CTTCTGCCGC TGCCTTTGCC 
TCTGCTGGAG ATACCACAGC TATGTCTGCC TTCAACCTGC TGCACTTGGT GACGAAGAGC 
CAGCCCGTGG CCCCGAGAGC CTGCGGGCTC CCCTCAGGCT GGCCTGCCTT CCATGATGTG 
ATCAGTTCGG AGGCCATCGA GTTCACAGAT GACTTTTCCT ACGGGATGCA CAGGGTGGAA 
ACCAGCTGTT CTCAGTGTGG TGCTCATCTC GGGCACATTT TTGACGATGG ACCTCGTCCG 
ACCGGCAAAA GATACTGCAT CAACTCAGCA TCCTTGTCCT TCACTCCTGC AGACAGCAGT 
GAGGCAGAAG GAAGCGGCAT CAAAGAGAGC GGCAGCCCAG CAGCAGCAGA CAGAGCTGAG 
CTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Msrb3 ( NM_177092.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796066.1 Mus musculus methionine sulfoxide reductase B3 (Msrb3), mRNA.

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CloneID	OMu13133
Clone ID Related Accession (Same CDS sequence)	NM_177092.4
Accession Version	NM_177092.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Mus musculus(house mouse)
Product	methionine-R-sulfoxide reductase B3, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB617432.1, AK086975.1 and BC096447.1. On Jul 24, 2008 this sequence version replaced NM_177092.3. ##Evidence-Data-START## Transcript exon combination :: AK137163.1, AK086975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTGCCT TCAACCTGCT GCACTTGGTG ACGAAGAGCC AGCCCGTGGC CCCGAGAGCC 
TGCGGGCTCC CCTCAGGGTC ATGTAGGGAT AAAAAGAACT GTAAGGTGGT CTTTTCCCAG 
CAGGAACTGA GGAAGCGGCT GACACCCCTA CAGTACCATG TCACTCAGGA GAAAGGAACT 
GAAAGTGCCT TTGAAGGAGA GTACACACAT CACAAAGATC CTGGAATATA TAAATGTGTT 
GTCTGTGGAA CTCCGTTGTT CAAGTCAGAA ACCAAATTTG ACTCTGGTTC AGGCTGGCCT 
GCCTTCCATG ATGTGATCAG TTCGGAGGCC ATCGAGTTCA CAGATGACTT TTCCTACGGG 
ATGCACAGGG TGGAAACCAG CTGTTCTCAG TGTGGTGCTC ATCTCGGGCA CATTTTTGAC 
GATGGACCTC GTCCGACCGG CAAAAGATAC TGCATCAACT CAGCATCCTT GTCCTTCACT 
CCTGCAGACA GCAGTGAGGC AGAAGGAAGC GGCATCAAAG AGAGCGGCAG CCCAGCAGCA 
GCAGACAGAG CTGAGCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796066.1
CDS	181..741
Translation	MSAFNLLHLVTKSQPVAPRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL

Target ORF information:

RefSeq Version	NM_177092.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus methionine sulfoxide reductase B3 (Msrb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177092.4

ORF Insert Sequence:

ATGTCTGCCT TCAACCTGCT GCACTTGGTG ACGAAGAGCC AGCCCGTGGC CCCGAGAGCC 
TGCGGGCTCC CCTCAGGGTC ATGTAGGGAT AAAAAGAACT GTAAGGTGGT CTTTTCCCAG 
CAGGAACTGA GGAAGCGGCT GACACCCCTA CAGTACCATG TCACTCAGGA GAAAGGAACT 
GAAAGTGCCT TTGAAGGAGA GTACACACAT CACAAAGATC CTGGAATATA TAAATGTGTT 
GTCTGTGGAA CTCCGTTGTT CAAGTCAGAA ACCAAATTTG ACTCTGGTTC AGGCTGGCCT 
GCCTTCCATG ATGTGATCAG TTCGGAGGCC ATCGAGTTCA CAGATGACTT TTCCTACGGG 
ATGCACAGGG TGGAAACCAG CTGTTCTCAG TGTGGTGCTC ATCTCGGGCA CATTTTTGAC 
GATGGACCTC GTCCGACCGG CAAAAGATAC TGCATCAACT CAGCATCCTT GTCCTTCACT 
CCTGCAGACA GCAGTGAGGC AGAAGGAAGC GGCATCAAAG AGAGCGGCAG CCCAGCAGCA 
GCAGACAGAG CTGAGCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Methionine sulfoxide reductase B3 deficiency stimulates heme oxygenase-1 expression via ROS-dependent and Nrf2 activation pathways.
Biochemical and biophysical research communications473(4)1033-1038(2016 05)
Kwak GH,Kim KY,Kim HY

Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.
Antioxidants & redox signaling24(11)590-602(2016 Apr)
Kim MA,Cho HJ,Bae SH,Lee B,Oh SK,Kwon TJ,Ryoo ZY,Kim HY,Cho JH,Kim UK,Lee KY

Methionine sulfoxide reductase B3 deficiency inhibits cell growth through the activation of p53-p21 and p27 pathways.
Archives of biochemistry and biophysics5471-5(2014 Apr)
Lee E,Kwak GH,Kamble K,Kim HY

Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.
Human molecular genetics23(6)1591-601(2014 Mar)
Kwon TJ,Cho HJ,Kim UK,Lee E,Oh SK,Bok J,Bae YC,Yi JK,Lee JW,Ryoo ZY,Lee SH,Lee KY,Kim HY

Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase.
Biochemical and biophysical research communications320(4)1277-83(2004 Aug)
Kim HY,Gladyshev VN

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Msrb3 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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