Lsm2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsm2
Entrez Gene ID	27756
Full Name	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Synonyms	D17H6S56E-2,D17H6S56E2,Dmapl,Dmpkap,G7b,Sm-X5,SmX5,snRNP
General protein information	Preferred Names LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated Names U6 snRNA-associated Sm-like protein LSm2 G7b alternative form LSM2 homolog, U6 small nuclear RNA associated dystrophia myotonica-protein kinase associated protein small ribonuclear protein G7b snRNP core Sm-like protein Sm-x5 snRNP core protein SMX5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 B1\|17 18.52 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001204273.1	NP_001191202.1	U6 snRNA-associated Sm-like protein LSm2 isoform 3
NM_001204274.1	NP_001191203.1	U6 snRNA-associated Sm-like protein LSm2 isoform 4
NM_001110101.2	NP_001103571.1	U6 snRNA-associated Sm-like protein LSm2 isoform 2
NM_030597.3	NP_085100.1	U6 snRNA-associated Sm-like protein LSm2 isoform 1

Pathways from BioSystems

Homologies

Neurospora crassa	NCU07382	XP_958875.2
Caenorhabditis elegans (roundworm)	gut-2	NP_001256511.1
Pan troglodytes (chimpanzee)	LSM2	XP_518362.3
Rattus norvegicus (Norway rat)	Lsm2	NP_001004073.1
Magnaporthe oryzae (rice blast fungus)	MGG_00355	XP_003718727.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005136	XP_314020.2
Schizosaccharomyces pombe (fission yeast)	lsm2	NP_588459.1
Saccharomyces cerevisiae (baker's yeast)	LSM2	NP_009527.1
Kluyveromyces lactis	KLLA0F09207g	XP_455499.1
Homo sapiens (human)	LSM2	NP_067000.1
Macaca mulatta (Rhesus monkey)	LSM2	XP_001105870.1
Danio rerio (zebrafish)	smx5	NP_571571.1
Eremothecium gossypii	AGOS_AFR182C	NP_985729.1
Canis lupus familiaris (dog)	LOC474849	XP_532081.3
Mus musculus (house mouse)	Lsm2	NP_085100.1
Drosophila melanogaster (fruit fly)	CG10418	NP_648570.1
Arabidopsis thaliana (thale cress)	AT1G03330	NP_563682.1
Oryza sativa (rice)	Os08g0154700	NP_001061016.2
Bos taurus (cattle)	LSM2	NP_001094647.1
Xenopus tropicalis (tropical clawed frog)	lsm2	NP_001016402.1

Gene Ontology
Bibliography

Related articles in PubMed

Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region.
van Kooij M, de Groot K, van Vugt H, Aten J, Snoek M
Immunogenetics53(8)656-61(2001 Oct)

The mouse as a model for the effects of MHC genes on human disease.
Allcock RJ, Martin AM, Price P
Immunology today21(7)328-32(2000 Jul)

The sequence and organization of the mouse valyl-tRNA synthetase gene G7a/Bat6 located in the MHC class III region.
Snoek M, van Vugt H
Immunogenetics49(5)468-70(1999 May)

Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility.
Snoek M, Teuscher C, van Vugt H
Journal of immunology (Baltimore, Md. : 1950)160(1)266-72(1998 Jan)

A gene belonging to the Sm family of snRNP core proteins maps within the mouse MHC.
Bedian V, Adams T, Geiger EA, Bailey LC, Gasser DL
Immunogenetics46(5)427-30(1997)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lsm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02564	NM_001204273.1 Latest version!	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu02566	NM_001204274.1 Latest version!	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu08307	NM_030597.3 Latest version!	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu04469	NM_001110101.2 Latest version!	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsm2 ( NM_001204273.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001191202.1 Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu02564
Clone ID Related Accession (Same CDS sequence)	NM_001204273.1
Accession Version	NM_001204273.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087117.9. Transcript Variant: This variant (3) includes an alternate internal exon, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF204154.1, AF204155.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164133 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTTT GGGGGAAACC TTTAGCAAGT CCAAGAGAAA GCCCACGGGC GCCGGGGGAG 
AACGGGAAGC GAGCCTTGCA CTTCTGTGCT GTTGACGAGG ACTTTGTGAG GCTCTTCTAC 
TCCTTTTTCA AGTCTCTTGT GGGCAAGGAT GTAGTCGTGG AACTCAAGAA TGACCTGAGA 
ACTCACAGAT GCTGCCTGCA GGCCTCAGCA TCTGTGGAAC CCTCCACTCT GTGGACCAGT 
ACCTCAATAT CAAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191202.1
CDS	128..385
Translation	MVFWGKPLASPRESPRAPGENGKRALHFCAVDEDFVRLFYSFFKSLVGKDVVVELKNDLRTHRCCLQASASVEPSTLWTSTSISN

Target ORF information:

RefSeq Version	NM_001204273.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204273.1

ORF Insert Sequence:

ATGGTGTTTT GGGGGAAACC TTTAGCAAGT CCAAGAGAAA GCCCACGGGC GCCGGGGGAG 
AACGGGAAGC GAGCCTTGCA CTTCTGTGCT GTTGACGAGG ACTTTGTGAG GCTCTTCTAC 
TCCTTTTTCA AGTCTCTTGT GGGCAAGGAT GTAGTCGTGG AACTCAAGAA TGACCTGAGA 
ACTCACAGAT GCTGCCTGCA GGCCTCAGCA TCTGTGGAAC CCTCCACTCT GTGGACCAGT 
ACCTCAATAT CAAACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm2 ( NM_001204274.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001191203.1 Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu02566
Clone ID Related Accession (Same CDS sequence)	NM_001204274.1
Accession Version	NM_001204274.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 225bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm2 isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087117.9. Transcript Variant: This variant (4) differs in the 5' UTR and has multiple differences in the coding region, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BI645534.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN01164133, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTTCT ACTCCTTTTT CAAGTCTCTT GTGGGCAAGG ATGTAGTCGT GGAACTCAAG 
AATGACCTGA GCATCTGTGG AACCCTCCAC TCTGTGGACC AGTACCTCAA TATCAAACTA 
ACCGACATCA GTGTCACAGA CCCTGAGAAA TACCCTCACT TCCCCATTGG TGACCCAGAA 
CTTGACGTCC TACTGAGGAC AAGAACACCC CTGCCCAATA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191203.1
CDS	230..454
Translation	MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHFPIGDPELDVLLRTRTPLPNT

Target ORF information:

RefSeq Version	NM_001204274.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204274.1

ORF Insert Sequence:

ATGCTCTTCT ACTCCTTTTT CAAGTCTCTT GTGGGCAAGG ATGTAGTCGT GGAACTCAAG 
AATGACCTGA GCATCTGTGG AACCCTCCAC TCTGTGGACC AGTACCTCAA TATCAAACTA 
ACCGACATCA GTGTCACAGA CCCTGAGAAA TACCCTCACT TCCCCATTGG TGACCCAGAA 
CTTGACGTCC TACTGAGGAC AAGAACACCC CTGCCCAATA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm2 ( NM_030597.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_085100.1 Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu08307
Clone ID Related Accession (Same CDS sequence)	NM_030597.3
Accession Version	NM_030597.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 396bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1572796800000
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB848823.1 and AF204150.1. On Oct 23, 2007 this sequence version replaced NM_030597.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC049543.1, CO796472.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTTT GGGGGAAACC TTTAGCAAGT CCAAGAGAAA GCCCACGGGC GCCGGGGGAG 
AACGGGAAGC GAGCCTTGCA CTTCTGTGCT GTTGACGAGG ACTTTGTGAG GCTCTTCTAC 
TCCTTTTTCA AGTCTCTTGT GGGCAAGGAT GTAGTCGTGG AACTCAAGAA TGACCTGAGC 
ATCTGTGGAA CCCTCCACTC TGTGGACCAG TACCTCAATA TCAAACTAAC CGACATCAGT 
GTCACAGACC CTGAGAAATA CCCTCACATG TTATCAGTCA AGAACTGCTT CATCAGGGGC 
TCAGTCGTCC GCTATGTGCA GCTGCCAGCA GATGAGGTGG ACACACAACT GCTACAGGAT 
GCAGCAAGGA AGGAAGCCCT TCAGCAGAAG CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_085100.1
CDS	128..523
Translation	MVFWGKPLASPRESPRAPGENGKRALHFCAVDEDFVRLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ

Target ORF information:

RefSeq Version	NM_030597.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030597.3

ORF Insert Sequence:

ATGGTGTTTT GGGGGAAACC TTTAGCAAGT CCAAGAGAAA GCCCACGGGC GCCGGGGGAG 
AACGGGAAGC GAGCCTTGCA CTTCTGTGCT GTTGACGAGG ACTTTGTGAG GCTCTTCTAC 
TCCTTTTTCA AGTCTCTTGT GGGCAAGGAT GTAGTCGTGG AACTCAAGAA TGACCTGAGC 
ATCTGTGGAA CCCTCCACTC TGTGGACCAG TACCTCAATA TCAAACTAAC CGACATCAGT 
GTCACAGACC CTGAGAAATA CCCTCACATG TTATCAGTCA AGAACTGCTT CATCAGGGGC 
TCAGTCGTCC GCTATGTGCA GCTGCCAGCA GATGAGGTGG ACACACAACT GCTACAGGAT 
GCAGCAAGGA AGGAAGCCCT TCAGCAGAAG CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm2 ( NM_001110101.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001103571.1 Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04469
Clone ID Related Accession (Same CDS sequence)	NM_001110101.2
Accession Version	NM_001110101.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 288bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	U6 snRNA-associated Sm-like protein LSm2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC087117.9, AK151605.1 and AF204150.1. On Feb 24, 2011 this sequence version replaced NM_001110101.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks an exon in the 5' coding region and uses an upstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compare to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014288.1, AK151605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCTTCT ACTCCTTTTT CAAGTCTCTT GTGGGCAAGG ATGTAGTCGT GGAACTCAAG 
AATGACCTGA GCATCTGTGG AACCCTCCAC TCTGTGGACC AGTACCTCAA TATCAAACTA 
ACCGACATCA GTGTCACAGA CCCTGAGAAA TACCCTCACA TGTTATCAGT CAAGAACTGC 
TTCATCAGGG GCTCAGTCGT CCGCTATGTG CAGCTGCCAG CAGATGAGGT GGACACACAA 
CTGCTACAGG ATGCAGCAAG GAAGGAAGCC CTTCAGCAGA AGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103571.1
CDS	230..517
Translation	MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ

Target ORF information:

RefSeq Version	NM_001110101.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110101.2

ORF Insert Sequence:

ATGCTCTTCT ACTCCTTTTT CAAGTCTCTT GTGGGCAAGG ATGTAGTCGT GGAACTCAAG 
AATGACCTGA GCATCTGTGG AACCCTCCAC TCTGTGGACC AGTACCTCAA TATCAAACTA 
ACCGACATCA GTGTCACAGA CCCTGAGAAA TACCCTCACA TGTTATCAGT CAAGAACTGC 
TTCATCAGGG GCTCAGTCGT CCGCTATGTG CAGCTGCCAG CAGATGAGGT GGACACACAA 
CTGCTACAGG ATGCAGCAAG GAAGGAAGCC CTTCAGCAGA AGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region.
Immunogenetics53(8)656-61(2001 Oct)
van Kooij M,de Groot K,van Vugt H,Aten J,Snoek M

The mouse as a model for the effects of MHC genes on human disease.
Immunology today21(7)328-32(2000 Jul)
Allcock RJ,Martin AM,Price P

The sequence and organization of the mouse valyl-tRNA synthetase gene G7a/Bat6 located in the MHC class III region.
Immunogenetics49(5)468-70(1999 May)
Snoek M,van Vugt H

Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility.
Journal of immunology (Baltimore, Md. : 1950)160(1)266-72(1998 Jan)
Snoek M,Teuscher C,van Vugt H

A gene belonging to the Sm family of snRNP core proteins maps within the mouse MHC.
Immunogenetics46(5)427-30(1997)
Bedian V,Adams T,Geiger EA,Bailey LC,Gasser DL