Cul3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cul3
Entrez Gene ID	26554
Full Name	cullin 3
Synonyms	KIAA0617
General protein information	Preferred Names cullin 3 Names cullin-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 C5

mRNA and Protein(s)

mRNA	Protein	Name
XM_006496498.3	XP_006496561.1	cullin-3 isoform X2
NM_001313728.1	NP_001300657.1	cullin-3 isoform 2 precursor
XM_030254438.1	XP_030110298.1	cullin-3 isoform X1
XM_006496497.3	XP_006496560.1	cullin-3 isoform X1
XM_030254443.1	XP_030110303.1	cullin-3 isoform X2
XM_006496498.4	XP_006496561.1	cullin-3 isoform X3
NM_016716.5	NP_057925.1	cullin-3 isoform 1

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os08g0170900	NP_001061094.1
Danio rerio (zebrafish)	cul3b	NP_001177414.1
Xenopus tropicalis (tropical clawed frog)	cul3	NP_001015975.2
Macaca mulatta (Rhesus monkey)	CUL3	XP_001109745.1
Oryza sativa (rice)	Os04g0643000	NP_001054047.1
Homo sapiens (human)	CUL3	NP_003581.1
Canis lupus familiaris (dog)	CUL3	XP_534586.3
Mus musculus (house mouse)	Cul3	NP_057925.1
Drosophila melanogaster (fruit fly)	Cul-3	NP_723907.1
Caenorhabditis elegans (roundworm)	cul-3	NP_503151.1
Pan troglodytes (chimpanzee)	CUL3	XP_001167528.1
Bos taurus (cattle)	CUL3	NP_001179735.1
Rattus norvegicus (Norway rat)	Cul3	NP_001100393.1
Gallus gallus (chicken)	CUL3	XP_422620.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008105	XP_317352.3

Gene Ontology
Bibliography

Related articles in PubMed

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Saritas T, Cuevas CA, Ferdaus MZ, Kuppe C, Kramann R, Moeller MJ, Floege J, Singer JD, McCormick JA
Scientific reports9(1)4596(2019 Mar)

Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
Yoshida S, Araki Y, Mori T, Sasaki E, Kasagi Y, Isobe K, Susa K, Inoue Y, Bomont P, Okado T, Rai T, Uchida S, Sohara E
Clinical and experimental nephrology22(6)1251-1257(2018 Dec)

Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
McMahon M, Swift SR, Hayes JD
Toxicology and applied pharmacology36045-57(2018 12)

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
Cornelius RJ, Zhang C, Erspamer KJ, Agbor LN, Sigmund CD, Singer JD, Yang CL, Ellison DH
American journal of physiology. Renal physiology315(4)F1006-F1018(2018 10)

Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter.
Raghavan S, Singh NK, Mani AM, Rao GN
The Journal of biological chemistry293(27)10574-10589(2018 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cul3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cul3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10443	NM_016716.5 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu69223	NM_001313728.1 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu27773	XM_006496497.3 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu27773	XM_030254443.1 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu27774	XM_006496498.4 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OMu69223	XM_030254438.1 Latest version!	Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu27774	XM_006496498.3	Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cul3 ( NM_016716.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_057925.1 Mus musculus cullin 3 (Cul3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10443
Clone ID Related Accession (Same CDS sequence)	NM_016716.5
Accession Version	NM_016716.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577462400000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161416.2, AF129738.1, AK003885.1, AK034695.1, BE991461.1 and BM899470.1. On Aug 27, 2015 this sequence version replaced NM_016716.4. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF129738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGAATC TGAGCAAAGG CACGGGCAGC CGGAAGGACA CCAAGATGCG GATCCGGGCC 
TTTCCGATGA CCATGGATGA AAAATATGTA AACAGCATTT GGGACCTTCT GAAAAATGCA 
ATTCAAGAAA TCCAGCGTAA GAATAACAGT GGTCTTAGTT TTGAGGAGCT CTATAGAAAT 
GCATATACAA TGGTTTTGCA TAAACATGGA GAAAAGCTCT ACACTGGACT AAGAGAAGTT 
GTTACTGAAC ATCTCATAAA TAAGGTGCGA GAAGATGTAC TAAATTCATT GAATAACAAC 
TTTCTTCAAA CACTAAATCA AGCTTGGAAT GATCATCAAA CAGCCATGGT GATGATTAGA 
GACATATTAA TGTATATGGA CCGTGTATAT GTACAACAGA ATAATGTAGA AAATGTCTAC 
AATTTGGGAT TAATAATTTT TCGAGATCAA GTTGTACGGT ATGGGTGTAT TAGGGATCAT 
CTTCGGCAAA CTTTATTGGA TATGATTGCC AGAGAGCGGA AAGGAGAAGT TGTAGACAGA 
GGAGCAATAA GAAATGCTTG CCAGATGTTA ATGATTTTAG GTCTTGAAGG AAGATCAGTC 
TATGAGGAAG ATTTTGAGGC TCCGTTTTTG GAAATGTCTG CAGAATTTTT TCAGATGGAA 
AGCCAGAAAT TTTTAGCAGA AAACAGTGCT TCAGTATATA TAAAGAAAGT AGAAGCTAGG 
ATTAATGAGG AAATAGAGCG GGTGATGCAC TGCCTTGACA AATCCACAGA AGAGCCTATT 
GTGAAGGTGG TGGAGAGGGA ACTCATTTCC AAGCACATGA AGACTATTGT AGAAATGGAA 
AATTCTGGGC TAGTACATAT GCTGAAAAAT GGAAAGACAG AAGACCTTGC TTGCATGTAC 
AAATTATTTA GTCGTGTGCC AAATGGTTTG AAGACCATGT GTGAATGTAT GAGTTGTTAT 
TTGAGGGAAC AAGGAAAAGC CCTTGTTTCT GAGGAAGGAG AAGGGAAGAA TCCTGTTGAC 
TATATCCAGG GCTTATTGGA TCTAAAGAGT AGGTTTGATC GCTTCCTCCA AGAATCCTTC 
AATAATGACC GGCTCTTTAA ACAGACTATT GCTGGGGACT TCGAGTATTT CTTAAACCTC 
AACTCTAGGT CTCCTGAATA CCTCTCATTA TTTATTGATG ATAAACTGAA AAAGGGAGTC 
AAAGGGCTAA CAGAACAAGA AGTAGAAACA ATATTGGATA AGGCAATGGT CCTTTTTAGG 
TTTATGCAAG AAAAAGATGT ATTTGAACGT TATTATAAAC AACACCTGGC AAGAAGACTG 
CTCACAAATA AAAGTGTTTC TGATGACTCT GAGAAAAATA TGATTTCTAA ATTAAAGACT 
GAGTGTGGAT GTCAATTCAC ATCGAAACTG GAAGGAATGT TTAGGGATAT GAGCATCTCA 
AACACAACTA TGGATGAGTT CAGGCAACAT CTACAGGCAA CGGGGGTCTC TTTAGGTGGT 
GTTGATCTCA CAGTCCGGGT TCTCACAACG GGATATTGGC CTACTCAGTC AGCCACACCA 
AAGTGCAACA TCCCACCAGC ACCAAGACAT GCTTTTGAGA TATTTAGAAG GTTCTACTTA 
GCCAAACACA GTGGTCGACA GCTCACACTC CAGCATCACA TGGGTTCTGC AGATCTCAAT 
GCCACCTTTT ATGGTCCAGT TAAAAAGGAA GATGGATCTG AGGTTGGTGT TGGCGGTGCA 
CAAGTAACTG GTTCTAATAC ACGGAAGCAC ATACTGCAAG TCTCCACTTT CCAGATGACC 
ATATTAATGC TTTTTAATAA TAGAGAGAAG TACACATTTG AGGAAATTCA ACAAGAGACA 
GATATCCCTG AAAGAGAACT TGTTAGAGCC CTCCAGTCCC TCGCCTGTGG TAAACCAACA 
CAGCGGGTCC TCACAAAAGA ACCCAAGTCC AAGGAGATAG AAAGTGGCCA CATATTTACA 
GTTAATGATC AATTCACATC TAAACTACAC AGAGTCAAGA TTCAAACAGT TGCAGCCAAA 
CAAGGTGAAT CCGACCCAGA AAGGAAAGAA ACAAGACAGA AAGTAGATGA TGACAGAAAA 
CATGAGATAG AAGCTGCTAT AGTGCGAATA ATGAAGTCTA GGAAGAAGAT GCAGCACAAT 
GTTTTAGTAG CAGAGGTAAC TCAGCAACTG AAGGCTCGAT TCTTACCAAG TCCAGTTGTT 
ATTAAGAAAC GTATTGAAGG ACTTATTGAG AGAGAATATT TGGCACGAAC ACCTGAGGAT 
CGCAAAGTAT ACACATATGT AGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057925.1
CDS	380..2686
Translation	MSNLSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	NM_016716.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016716.5

ORF Insert Sequence:

ATGTCGAATC TGAGCAAAGG CACGGGCAGC CGGAAGGACA CCAAGATGCG GATCCGGGCC 
TTTCCGATGA CCATGGATGA AAAATATGTA AACAGCATTT GGGACCTTCT GAAAAATGCA 
ATTCAAGAAA TCCAGCGTAA GAATAACAGT GGTCTTAGTT TTGAGGAGCT CTATAGAAAT 
GCATATACAA TGGTTTTGCA TAAACATGGA GAAAAGCTCT ACACTGGACT AAGAGAAGTT 
GTTACTGAAC ATCTCATAAA TAAGGTGCGA GAAGATGTAC TAAATTCATT GAATAACAAC 
TTTCTTCAAA CACTAAATCA AGCTTGGAAT GATCATCAAA CAGCCATGGT GATGATTAGA 
GACATATTAA TGTATATGGA CCGTGTATAT GTACAACAGA ATAATGTAGA AAATGTCTAC 
AATTTGGGAT TAATAATTTT TCGAGATCAA GTTGTACGGT ATGGGTGTAT TAGGGATCAT 
CTTCGGCAAA CTTTATTGGA TATGATTGCC AGAGAGCGGA AAGGAGAAGT TGTAGACAGA 
GGAGCAATAA GAAATGCTTG CCAGATGTTA ATGATTTTAG GTCTTGAAGG AAGATCAGTC 
TATGAGGAAG ATTTTGAGGC TCCGTTTTTG GAAATGTCTG CAGAATTTTT TCAGATGGAA 
AGCCAGAAAT TTTTAGCAGA AAACAGTGCT TCAGTATATA TAAAGAAAGT AGAAGCTAGG 
ATTAATGAGG AAATAGAGCG GGTGATGCAC TGCCTTGACA AATCCACAGA AGAGCCTATT 
GTGAAGGTGG TGGAGAGGGA ACTCATTTCC AAGCACATGA AGACTATTGT AGAAATGGAA 
AATTCTGGGC TAGTACATAT GCTGAAAAAT GGAAAGACAG AAGACCTTGC TTGCATGTAC 
AAATTATTTA GTCGTGTGCC AAATGGTTTG AAGACCATGT GTGAATGTAT GAGTTGTTAT 
TTGAGGGAAC AAGGAAAAGC CCTTGTTTCT GAGGAAGGAG AAGGGAAGAA TCCTGTTGAC 
TATATCCAGG GCTTATTGGA TCTAAAGAGT AGGTTTGATC GCTTCCTCCA AGAATCCTTC 
AATAATGACC GGCTCTTTAA ACAGACTATT GCTGGGGACT TCGAGTATTT CTTAAACCTC 
AACTCTAGGT CTCCTGAATA CCTCTCATTA TTTATTGATG ATAAACTGAA AAAGGGAGTC 
AAAGGGCTAA CAGAACAAGA AGTAGAAACA ATATTGGATA AGGCAATGGT CCTTTTTAGG 
TTTATGCAAG AAAAAGATGT ATTTGAACGT TATTATAAAC AACACCTGGC AAGAAGACTG 
CTCACAAATA AAAGTGTTTC TGATGACTCT GAGAAAAATA TGATTTCTAA ATTAAAGACT 
GAGTGTGGAT GTCAATTCAC ATCGAAACTG GAAGGAATGT TTAGGGATAT GAGCATCTCA 
AACACAACTA TGGATGAGTT CAGGCAACAT CTACAGGCAA CGGGGGTCTC TTTAGGTGGT 
GTTGATCTCA CAGTCCGGGT TCTCACAACG GGATATTGGC CTACTCAGTC AGCCACACCA 
AAGTGCAACA TCCCACCAGC ACCAAGACAT GCTTTTGAGA TATTTAGAAG GTTCTACTTA 
GCCAAACACA GTGGTCGACA GCTCACACTC CAGCATCACA TGGGTTCTGC AGATCTCAAT 
GCCACCTTTT ATGGTCCAGT TAAAAAGGAA GATGGATCTG AGGTTGGTGT TGGCGGTGCA 
CAAGTAACTG GTTCTAATAC ACGGAAGCAC ATACTGCAAG TCTCCACTTT CCAGATGACC 
ATATTAATGC TTTTTAATAA TAGAGAGAAG TACACATTTG AGGAAATTCA ACAAGAGACA 
GATATCCCTG AAAGAGAACT TGTTAGAGCC CTCCAGTCCC TCGCCTGTGG TAAACCAACA 
CAGCGGGTCC TCACAAAAGA ACCCAAGTCC AAGGAGATAG AAAGTGGCCA CATATTTACA 
GTTAATGATC AATTCACATC TAAACTACAC AGAGTCAAGA TTCAAACAGT TGCAGCCAAA 
CAAGGTGAAT CCGACCCAGA AAGGAAAGAA ACAAGACAGA AAGTAGATGA TGACAGAAAA 
CATGAGATAG AAGCTGCTAT AGTGCGAATA ATGAAGTCTA GGAAGAAGAT GCAGCACAAT 
GTTTTAGTAG CAGAGGTAAC TCAGCAACTG AAGGCTCGAT TCTTACCAAG TCCAGTTGTT 
ATTAAGAAAC GTATTGAAGG ACTTATTGAG AGAGAATATT TGGCACGAAC ACCTGAGGAT 
CGCAAAGTAT ACACATATGT AGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( NM_001313728.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001300657.1 Mus musculus cullin 3 (Cul3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu69223
Clone ID Related Accession (Same CDS sequence)	NM_001313728.1 , XM_030254438.1
Accession Version	NM_001313728.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577462400000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161416.2, AF129738.1, AC166157.5, CK634506.1, AK003885.1, AK034695.1, BE991461.1 and BM899470.1. On Aug 27, 2015 this sequence version replaced XM_006496495.2. Transcript Variant: This variant (2) contains an alternate exon in the 5' region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a shorter, distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK129174.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTGTC CTCAGTGCAT CACATCAGGA GGCACATGCT GTCAGTTTAT CCCATTATTG 
GTGATGTTAA CTTTGATCAC TTGGTGTCCG CCAGATTTCT TCACTGTAAA GGTGCGAGAA 
GATGTACTAA ATTCATTGAA TAACAACTTT CTTCAAACAC TAAATCAAGC TTGGAATGAT 
CATCAAACAG CCATGGTGAT GATTAGAGAC ATATTAATGT ATATGGACCG TGTATATGTA 
CAACAGAATA ATGTAGAAAA TGTCTACAAT TTGGGATTAA TAATTTTTCG AGATCAAGTT 
GTACGGTATG GGTGTATTAG GGATCATCTT CGGCAAACTT TATTGGATAT GATTGCCAGA 
GAGCGGAAAG GAGAAGTTGT AGACAGAGGA GCAATAAGAA ATGCTTGCCA GATGTTAATG 
ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT GAGGAAGATT TTGAGGCTCC GTTTTTGGAA 
ATGTCTGCAG AATTTTTTCA GATGGAAAGC CAGAAATTTT TAGCAGAAAA CAGTGCTTCA 
GTATATATAA AGAAAGTAGA AGCTAGGATT AATGAGGAAA TAGAGCGGGT GATGCACTGC 
CTTGACAAAT CCACAGAAGA GCCTATTGTG AAGGTGGTGG AGAGGGAACT CATTTCCAAG 
CACATGAAGA CTATTGTAGA AATGGAAAAT TCTGGGCTAG TACATATGCT GAAAAATGGA 
AAGACAGAAG ACCTTGCTTG CATGTACAAA TTATTTAGTC GTGTGCCAAA TGGTTTGAAG 
ACCATGTGTG AATGTATGAG TTGTTATTTG AGGGAACAAG GAAAAGCCCT TGTTTCTGAG 
GAAGGAGAAG GGAAGAATCC TGTTGACTAT ATCCAGGGCT TATTGGATCT AAAGAGTAGG 
TTTGATCGCT TCCTCCAAGA ATCCTTCAAT AATGACCGGC TCTTTAAACA GACTATTGCT 
GGGGACTTCG AGTATTTCTT AAACCTCAAC TCTAGGTCTC CTGAATACCT CTCATTATTT 
ATTGATGATA AACTGAAAAA GGGAGTCAAA GGGCTAACAG AACAAGAAGT AGAAACAATA 
TTGGATAAGG CAATGGTCCT TTTTAGGTTT ATGCAAGAAA AAGATGTATT TGAACGTTAT 
TATAAACAAC ACCTGGCAAG AAGACTGCTC ACAAATAAAA GTGTTTCTGA TGACTCTGAG 
AAAAATATGA TTTCTAAATT AAAGACTGAG TGTGGATGTC AATTCACATC GAAACTGGAA 
GGAATGTTTA GGGATATGAG CATCTCAAAC ACAACTATGG ATGAGTTCAG GCAACATCTA 
CAGGCAACGG GGGTCTCTTT AGGTGGTGTT GATCTCACAG TCCGGGTTCT CACAACGGGA 
TATTGGCCTA CTCAGTCAGC CACACCAAAG TGCAACATCC CACCAGCACC AAGACATGCT 
TTTGAGATAT TTAGAAGGTT CTACTTAGCC AAACACAGTG GTCGACAGCT CACACTCCAG 
CATCACATGG GTTCTGCAGA TCTCAATGCC ACCTTTTATG GTCCAGTTAA AAAGGAAGAT 
GGATCTGAGG TTGGTGTTGG CGGTGCACAA GTAACTGGTT CTAATACACG GAAGCACATA 
CTGCAAGTCT CCACTTTCCA GATGACCATA TTAATGCTTT TTAATAATAG AGAGAAGTAC 
ACATTTGAGG AAATTCAACA AGAGACAGAT ATCCCTGAAA GAGAACTTGT TAGAGCCCTC 
CAGTCCCTCG CCTGTGGTAA ACCAACACAG CGGGTCCTCA CAAAAGAACC CAAGTCCAAG 
GAGATAGAAA GTGGCCACAT ATTTACAGTT AATGATCAAT TCACATCTAA ACTACACAGA 
GTCAAGATTC AAACAGTTGC AGCCAAACAA GGTGAATCCG ACCCAGAAAG GAAAGAAACA 
AGACAGAAAG TAGATGATGA CAGAAAACAT GAGATAGAAG CTGCTATAGT GCGAATAATG 
AAGTCTAGGA AGAAGATGCA GCACAATGTT TTAGTAGCAG AGGTAACTCA GCAACTGAAG 
GCTCGATTCT TACCAAGTCC AGTTGTTATT AAGAAACGTA TTGAAGGACT TATTGAGAGA 
GAATATTTGG CACGAACACC TGAGGATCGC AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001300657.1
CDS	661..2814
Translation	MLCPQCITSGGTCCQFIPLLVMLTLITWCPPDFFTVKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	NM_001313728.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001313728.1

ORF Insert Sequence:

ATGTTGTGTC CTCAGTGCAT CACATCAGGA GGCACATGCT GTCAGTTTAT CCCATTATTG 
GTGATGTTAA CTTTGATCAC TTGGTGTCCG CCAGATTTCT TCACTGTAAA GGTGCGAGAA 
GATGTACTAA ATTCATTGAA TAACAACTTT CTTCAAACAC TAAATCAAGC TTGGAATGAT 
CATCAAACAG CCATGGTGAT GATTAGAGAC ATATTAATGT ATATGGACCG TGTATATGTA 
CAACAGAATA ATGTAGAAAA TGTCTACAAT TTGGGATTAA TAATTTTTCG AGATCAAGTT 
GTACGGTATG GGTGTATTAG GGATCATCTT CGGCAAACTT TATTGGATAT GATTGCCAGA 
GAGCGGAAAG GAGAAGTTGT AGACAGAGGA GCAATAAGAA ATGCTTGCCA GATGTTAATG 
ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT GAGGAAGATT TTGAGGCTCC GTTTTTGGAA 
ATGTCTGCAG AATTTTTTCA GATGGAAAGC CAGAAATTTT TAGCAGAAAA CAGTGCTTCA 
GTATATATAA AGAAAGTAGA AGCTAGGATT AATGAGGAAA TAGAGCGGGT GATGCACTGC 
CTTGACAAAT CCACAGAAGA GCCTATTGTG AAGGTGGTGG AGAGGGAACT CATTTCCAAG 
CACATGAAGA CTATTGTAGA AATGGAAAAT TCTGGGCTAG TACATATGCT GAAAAATGGA 
AAGACAGAAG ACCTTGCTTG CATGTACAAA TTATTTAGTC GTGTGCCAAA TGGTTTGAAG 
ACCATGTGTG AATGTATGAG TTGTTATTTG AGGGAACAAG GAAAAGCCCT TGTTTCTGAG 
GAAGGAGAAG GGAAGAATCC TGTTGACTAT ATCCAGGGCT TATTGGATCT AAAGAGTAGG 
TTTGATCGCT TCCTCCAAGA ATCCTTCAAT AATGACCGGC TCTTTAAACA GACTATTGCT 
GGGGACTTCG AGTATTTCTT AAACCTCAAC TCTAGGTCTC CTGAATACCT CTCATTATTT 
ATTGATGATA AACTGAAAAA GGGAGTCAAA GGGCTAACAG AACAAGAAGT AGAAACAATA 
TTGGATAAGG CAATGGTCCT TTTTAGGTTT ATGCAAGAAA AAGATGTATT TGAACGTTAT 
TATAAACAAC ACCTGGCAAG AAGACTGCTC ACAAATAAAA GTGTTTCTGA TGACTCTGAG 
AAAAATATGA TTTCTAAATT AAAGACTGAG TGTGGATGTC AATTCACATC GAAACTGGAA 
GGAATGTTTA GGGATATGAG CATCTCAAAC ACAACTATGG ATGAGTTCAG GCAACATCTA 
CAGGCAACGG GGGTCTCTTT AGGTGGTGTT GATCTCACAG TCCGGGTTCT CACAACGGGA 
TATTGGCCTA CTCAGTCAGC CACACCAAAG TGCAACATCC CACCAGCACC AAGACATGCT 
TTTGAGATAT TTAGAAGGTT CTACTTAGCC AAACACAGTG GTCGACAGCT CACACTCCAG 
CATCACATGG GTTCTGCAGA TCTCAATGCC ACCTTTTATG GTCCAGTTAA AAAGGAAGAT 
GGATCTGAGG TTGGTGTTGG CGGTGCACAA GTAACTGGTT CTAATACACG GAAGCACATA 
CTGCAAGTCT CCACTTTCCA GATGACCATA TTAATGCTTT TTAATAATAG AGAGAAGTAC 
ACATTTGAGG AAATTCAACA AGAGACAGAT ATCCCTGAAA GAGAACTTGT TAGAGCCCTC 
CAGTCCCTCG CCTGTGGTAA ACCAACACAG CGGGTCCTCA CAAAAGAACC CAAGTCCAAG 
GAGATAGAAA GTGGCCACAT ATTTACAGTT AATGATCAAT TCACATCTAA ACTACACAGA 
GTCAAGATTC AAACAGTTGC AGCCAAACAA GGTGAATCCG ACCCAGAAAG GAAAGAAACA 
AGACAGAAAG TAGATGATGA CAGAAAACAT GAGATAGAAG CTGCTATAGT GCGAATAATG 
AAGTCTAGGA AGAAGATGCA GCACAATGTT TTAGTAGCAG AGGTAACTCA GCAACTGAAG 
GCTCGATTCT TACCAAGTCC AGTTGTTATT AAGAAACGTA TTGAAGGACT TATTGAGAGA 
GAATATTTGG CACGAACACC TGAGGATCGC AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( XM_006496497.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496560.1 Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu27773
Clone ID Related Accession (Same CDS sequence)	XM_006496497.3 , XM_030254443.1
Accession Version	XM_006496497.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006496497.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACTC TTCACCTGGA TGAATTTAAT GTGCGAGAAG ATGTACTAAA TTCATTGAAT 
AACAACTTTC TTCAAACACT AAATCAAGCT TGGAATGATC ATCAAACAGC CATGGTGATG 
ATTAGAGACA TATTAATGTA TATGGACCGT GTATATGTAC AACAGAATAA TGTAGAAAAT 
GTCTACAATT TGGGATTAAT AATTTTTCGA GATCAAGTTG TACGGTATGG GTGTATTAGG 
GATCATCTTC GGCAAACTTT ATTGGATATG ATTGCCAGAG AGCGGAAAGG AGAAGTTGTA 
GACAGAGGAG CAATAAGAAA TGCTTGCCAG ATGTTAATGA TTTTAGGTCT TGAAGGAAGA 
TCAGTCTATG AGGAAGATTT TGAGGCTCCG TTTTTGGAAA TGTCTGCAGA ATTTTTTCAG 
ATGGAAAGCC AGAAATTTTT AGCAGAAAAC AGTGCTTCAG TATATATAAA GAAAGTAGAA 
GCTAGGATTA ATGAGGAAAT AGAGCGGGTG ATGCACTGCC TTGACAAATC CACAGAAGAG 
CCTATTGTGA AGGTGGTGGA GAGGGAACTC ATTTCCAAGC ACATGAAGAC TATTGTAGAA 
ATGGAAAATT CTGGGCTAGT ACATATGCTG AAAAATGGAA AGACAGAAGA CCTTGCTTGC 
ATGTACAAAT TATTTAGTCG TGTGCCAAAT GGTTTGAAGA CCATGTGTGA ATGTATGAGT 
TGTTATTTGA GGGAACAAGG AAAAGCCCTT GTTTCTGAGG AAGGAGAAGG GAAGAATCCT 
GTTGACTATA TCCAGGGCTT ATTGGATCTA AAGAGTAGGT TTGATCGCTT CCTCCAAGAA 
TCCTTCAATA ATGACCGGCT CTTTAAACAG ACTATTGCTG GGGACTTCGA GTATTTCTTA 
AACCTCAACT CTAGGTCTCC TGAATACCTC TCATTATTTA TTGATGATAA ACTGAAAAAG 
GGAGTCAAAG GGCTAACAGA ACAAGAAGTA GAAACAATAT TGGATAAGGC AATGGTCCTT 
TTTAGGTTTA TGCAAGAAAA AGATGTATTT GAACGTTATT ATAAACAACA CCTGGCAAGA 
AGACTGCTCA CAAATAAAAG TGTTTCTGAT GACTCTGAGA AAAATATGAT TTCTAAATTA 
AAGACTGAGT GTGGATGTCA ATTCACATCG AAACTGGAAG GAATGTTTAG GGATATGAGC 
ATCTCAAACA CAACTATGGA TGAGTTCAGG CAACATCTAC AGGCAACGGG GGTCTCTTTA 
GGTGGTGTTG ATCTCACAGT CCGGGTTCTC ACAACGGGAT ATTGGCCTAC TCAGTCAGCC 
ACACCAAAGT GCAACATCCC ACCAGCACCA AGACATGCTT TTGAGATATT TAGAAGGTTC 
TACTTAGCCA AACACAGTGG TCGACAGCTC ACACTCCAGC ATCACATGGG TTCTGCAGAT 
CTCAATGCCA CCTTTTATGG TCCAGTTAAA AAGGAAGATG GATCTGAGGT TGGTGTTGGC 
GGTGCACAAG TAACTGGTTC TAATACACGG AAGCACATAC TGCAAGTCTC CACTTTCCAG 
ATGACCATAT TAATGCTTTT TAATAATAGA GAGAAGTACA CATTTGAGGA AATTCAACAA 
GAGACAGATA TCCCTGAAAG AGAACTTGTT AGAGCCCTCC AGTCCCTCGC CTGTGGTAAA 
CCAACACAGC GGGTCCTCAC AAAAGAACCC AAGTCCAAGG AGATAGAAAG TGGCCACATA 
TTTACAGTTA ATGATCAATT CACATCTAAA CTACACAGAG TCAAGATTCA AACAGTTGCA 
GCCAAACAAG GTGAATCCGA CCCAGAAAGG AAAGAAACAA GACAGAAAGT AGATGATGAC 
AGAAAACATG AGATAGAAGC TGCTATAGTG CGAATAATGA AGTCTAGGAA GAAGATGCAG 
CACAATGTTT TAGTAGCAGA GGTAACTCAG CAACTGAAGG CTCGATTCTT ACCAAGTCCA 
GTTGTTATTA AGAAACGTAT TGAAGGACTT ATTGAGAGAG AATATTTGGC ACGAACACCT 
GAGGATCGCA AAGTATACAC ATATGTAGCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496560.1
CDS	185..2257
Translation	MSTLHLDEFNVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	XM_006496497.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006496497.3

ORF Insert Sequence:

ATGTCAACTC TTCACCTGGA TGAATTTAAT GTGCGAGAAG ATGTACTAAA TTCATTGAAT 
AACAACTTTC TTCAAACACT AAATCAAGCT TGGAATGATC ATCAAACAGC CATGGTGATG 
ATTAGAGACA TATTAATGTA TATGGACCGT GTATATGTAC AACAGAATAA TGTAGAAAAT 
GTCTACAATT TGGGATTAAT AATTTTTCGA GATCAAGTTG TACGGTATGG GTGTATTAGG 
GATCATCTTC GGCAAACTTT ATTGGATATG ATTGCCAGAG AGCGGAAAGG AGAAGTTGTA 
GACAGAGGAG CAATAAGAAA TGCTTGCCAG ATGTTAATGA TTTTAGGTCT TGAAGGAAGA 
TCAGTCTATG AGGAAGATTT TGAGGCTCCG TTTTTGGAAA TGTCTGCAGA ATTTTTTCAG 
ATGGAAAGCC AGAAATTTTT AGCAGAAAAC AGTGCTTCAG TATATATAAA GAAAGTAGAA 
GCTAGGATTA ATGAGGAAAT AGAGCGGGTG ATGCACTGCC TTGACAAATC CACAGAAGAG 
CCTATTGTGA AGGTGGTGGA GAGGGAACTC ATTTCCAAGC ACATGAAGAC TATTGTAGAA 
ATGGAAAATT CTGGGCTAGT ACATATGCTG AAAAATGGAA AGACAGAAGA CCTTGCTTGC 
ATGTACAAAT TATTTAGTCG TGTGCCAAAT GGTTTGAAGA CCATGTGTGA ATGTATGAGT 
TGTTATTTGA GGGAACAAGG AAAAGCCCTT GTTTCTGAGG AAGGAGAAGG GAAGAATCCT 
GTTGACTATA TCCAGGGCTT ATTGGATCTA AAGAGTAGGT TTGATCGCTT CCTCCAAGAA 
TCCTTCAATA ATGACCGGCT CTTTAAACAG ACTATTGCTG GGGACTTCGA GTATTTCTTA 
AACCTCAACT CTAGGTCTCC TGAATACCTC TCATTATTTA TTGATGATAA ACTGAAAAAG 
GGAGTCAAAG GGCTAACAGA ACAAGAAGTA GAAACAATAT TGGATAAGGC AATGGTCCTT 
TTTAGGTTTA TGCAAGAAAA AGATGTATTT GAACGTTATT ATAAACAACA CCTGGCAAGA 
AGACTGCTCA CAAATAAAAG TGTTTCTGAT GACTCTGAGA AAAATATGAT TTCTAAATTA 
AAGACTGAGT GTGGATGTCA ATTCACATCG AAACTGGAAG GAATGTTTAG GGATATGAGC 
ATCTCAAACA CAACTATGGA TGAGTTCAGG CAACATCTAC AGGCAACGGG GGTCTCTTTA 
GGTGGTGTTG ATCTCACAGT CCGGGTTCTC ACAACGGGAT ATTGGCCTAC TCAGTCAGCC 
ACACCAAAGT GCAACATCCC ACCAGCACCA AGACATGCTT TTGAGATATT TAGAAGGTTC 
TACTTAGCCA AACACAGTGG TCGACAGCTC ACACTCCAGC ATCACATGGG TTCTGCAGAT 
CTCAATGCCA CCTTTTATGG TCCAGTTAAA AAGGAAGATG GATCTGAGGT TGGTGTTGGC 
GGTGCACAAG TAACTGGTTC TAATACACGG AAGCACATAC TGCAAGTCTC CACTTTCCAG 
ATGACCATAT TAATGCTTTT TAATAATAGA GAGAAGTACA CATTTGAGGA AATTCAACAA 
GAGACAGATA TCCCTGAAAG AGAACTTGTT AGAGCCCTCC AGTCCCTCGC CTGTGGTAAA 
CCAACACAGC GGGTCCTCAC AAAAGAACCC AAGTCCAAGG AGATAGAAAG TGGCCACATA 
TTTACAGTTA ATGATCAATT CACATCTAAA CTACACAGAG TCAAGATTCA AACAGTTGCA 
GCCAAACAAG GTGAATCCGA CCCAGAAAGG AAAGAAACAA GACAGAAAGT AGATGATGAC 
AGAAAACATG AGATAGAAGC TGCTATAGTG CGAATAATGA AGTCTAGGAA GAAGATGCAG 
CACAATGTTT TAGTAGCAGA GGTAACTCAG CAACTGAAGG CTCGATTCTT ACCAAGTCCA 
GTTGTTATTA AGAAACGTAT TGAAGGACTT ATTGAGAGAG AATATTTGGC ACGAACACCT 
GAGGATCGCA AAGTATACAC ATATGTAGCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( XM_030254443.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110303.1 Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu27773
Clone ID Related Accession (Same CDS sequence)	XM_006496497.3 , XM_030254443.1
Accession Version	XM_030254443.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACTC TTCACCTGGA TGAATTTAAT GTGCGAGAAG ATGTACTAAA TTCATTGAAT 
AACAACTTTC TTCAAACACT AAATCAAGCT TGGAATGATC ATCAAACAGC CATGGTGATG 
ATTAGAGACA TATTAATGTA TATGGACCGT GTATATGTAC AACAGAATAA TGTAGAAAAT 
GTCTACAATT TGGGATTAAT AATTTTTCGA GATCAAGTTG TACGGTATGG GTGTATTAGG 
GATCATCTTC GGCAAACTTT ATTGGATATG ATTGCCAGAG AGCGGAAAGG AGAAGTTGTA 
GACAGAGGAG CAATAAGAAA TGCTTGCCAG ATGTTAATGA TTTTAGGTCT TGAAGGAAGA 
TCAGTCTATG AGGAAGATTT TGAGGCTCCG TTTTTGGAAA TGTCTGCAGA ATTTTTTCAG 
ATGGAAAGCC AGAAATTTTT AGCAGAAAAC AGTGCTTCAG TATATATAAA GAAAGTAGAA 
GCTAGGATTA ATGAGGAAAT AGAGCGGGTG ATGCACTGCC TTGACAAATC CACAGAAGAG 
CCTATTGTGA AGGTGGTGGA GAGGGAACTC ATTTCCAAGC ACATGAAGAC TATTGTAGAA 
ATGGAAAATT CTGGGCTAGT ACATATGCTG AAAAATGGAA AGACAGAAGA CCTTGCTTGC 
ATGTACAAAT TATTTAGTCG TGTGCCAAAT GGTTTGAAGA CCATGTGTGA ATGTATGAGT 
TGTTATTTGA GGGAACAAGG AAAAGCCCTT GTTTCTGAGG AAGGAGAAGG GAAGAATCCT 
GTTGACTATA TCCAGGGCTT ATTGGATCTA AAGAGTAGGT TTGATCGCTT CCTCCAAGAA 
TCCTTCAATA ATGACCGGCT CTTTAAACAG ACTATTGCTG GGGACTTCGA GTATTTCTTA 
AACCTCAACT CTAGGTCTCC TGAATACCTC TCATTATTTA TTGATGATAA ACTGAAAAAG 
GGAGTCAAAG GGCTAACAGA ACAAGAAGTA GAAACAATAT TGGATAAGGC AATGGTCCTT 
TTTAGGTTTA TGCAAGAAAA AGATGTATTT GAACGTTATT ATAAACAACA CCTGGCAAGA 
AGACTGCTCA CAAATAAAAG TGTTTCTGAT GACTCTGAGA AAAATATGAT TTCTAAATTA 
AAGACTGAGT GTGGATGTCA ATTCACATCG AAACTGGAAG GAATGTTTAG GGATATGAGC 
ATCTCAAACA CAACTATGGA TGAGTTCAGG CAACATCTAC AGGCAACGGG GGTCTCTTTA 
GGTGGTGTTG ATCTCACAGT CCGGGTTCTC ACAACGGGAT ATTGGCCTAC TCAGTCAGCC 
ACACCAAAGT GCAACATCCC ACCAGCACCA AGACATGCTT TTGAGATATT TAGAAGGTTC 
TACTTAGCCA AACACAGTGG TCGACAGCTC ACACTCCAGC ATCACATGGG TTCTGCAGAT 
CTCAATGCCA CCTTTTATGG TCCAGTTAAA AAGGAAGATG GATCTGAGGT TGGTGTTGGC 
GGTGCACAAG TAACTGGTTC TAATACACGG AAGCACATAC TGCAAGTCTC CACTTTCCAG 
ATGACCATAT TAATGCTTTT TAATAATAGA GAGAAGTACA CATTTGAGGA AATTCAACAA 
GAGACAGATA TCCCTGAAAG AGAACTTGTT AGAGCCCTCC AGTCCCTCGC CTGTGGTAAA 
CCAACACAGC GGGTCCTCAC AAAAGAACCC AAGTCCAAGG AGATAGAAAG TGGCCACATA 
TTTACAGTTA ATGATCAATT CACATCTAAA CTACACAGAG TCAAGATTCA AACAGTTGCA 
GCCAAACAAG GTGAATCCGA CCCAGAAAGG AAAGAAACAA GACAGAAAGT AGATGATGAC 
AGAAAACATG AGATAGAAGC TGCTATAGTG CGAATAATGA AGTCTAGGAA GAAGATGCAG 
CACAATGTTT TAGTAGCAGA GGTAACTCAG CAACTGAAGG CTCGATTCTT ACCAAGTCCA 
GTTGTTATTA AGAAACGTAT TGAAGGACTT ATTGAGAGAG AATATTTGGC ACGAACACCT 
GAGGATCGCA AAGTATACAC ATATGTAGCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110303.1
CDS	40..2112
Translation	MSTLHLDEFNVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	XM_030254443.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254443.1

ORF Insert Sequence:

ATGTCAACTC TTCACCTGGA TGAATTTAAT GTGCGAGAAG ATGTACTAAA TTCATTGAAT 
AACAACTTTC TTCAAACACT AAATCAAGCT TGGAATGATC ATCAAACAGC CATGGTGATG 
ATTAGAGACA TATTAATGTA TATGGACCGT GTATATGTAC AACAGAATAA TGTAGAAAAT 
GTCTACAATT TGGGATTAAT AATTTTTCGA GATCAAGTTG TACGGTATGG GTGTATTAGG 
GATCATCTTC GGCAAACTTT ATTGGATATG ATTGCCAGAG AGCGGAAAGG AGAAGTTGTA 
GACAGAGGAG CAATAAGAAA TGCTTGCCAG ATGTTAATGA TTTTAGGTCT TGAAGGAAGA 
TCAGTCTATG AGGAAGATTT TGAGGCTCCG TTTTTGGAAA TGTCTGCAGA ATTTTTTCAG 
ATGGAAAGCC AGAAATTTTT AGCAGAAAAC AGTGCTTCAG TATATATAAA GAAAGTAGAA 
GCTAGGATTA ATGAGGAAAT AGAGCGGGTG ATGCACTGCC TTGACAAATC CACAGAAGAG 
CCTATTGTGA AGGTGGTGGA GAGGGAACTC ATTTCCAAGC ACATGAAGAC TATTGTAGAA 
ATGGAAAATT CTGGGCTAGT ACATATGCTG AAAAATGGAA AGACAGAAGA CCTTGCTTGC 
ATGTACAAAT TATTTAGTCG TGTGCCAAAT GGTTTGAAGA CCATGTGTGA ATGTATGAGT 
TGTTATTTGA GGGAACAAGG AAAAGCCCTT GTTTCTGAGG AAGGAGAAGG GAAGAATCCT 
GTTGACTATA TCCAGGGCTT ATTGGATCTA AAGAGTAGGT TTGATCGCTT CCTCCAAGAA 
TCCTTCAATA ATGACCGGCT CTTTAAACAG ACTATTGCTG GGGACTTCGA GTATTTCTTA 
AACCTCAACT CTAGGTCTCC TGAATACCTC TCATTATTTA TTGATGATAA ACTGAAAAAG 
GGAGTCAAAG GGCTAACAGA ACAAGAAGTA GAAACAATAT TGGATAAGGC AATGGTCCTT 
TTTAGGTTTA TGCAAGAAAA AGATGTATTT GAACGTTATT ATAAACAACA CCTGGCAAGA 
AGACTGCTCA CAAATAAAAG TGTTTCTGAT GACTCTGAGA AAAATATGAT TTCTAAATTA 
AAGACTGAGT GTGGATGTCA ATTCACATCG AAACTGGAAG GAATGTTTAG GGATATGAGC 
ATCTCAAACA CAACTATGGA TGAGTTCAGG CAACATCTAC AGGCAACGGG GGTCTCTTTA 
GGTGGTGTTG ATCTCACAGT CCGGGTTCTC ACAACGGGAT ATTGGCCTAC TCAGTCAGCC 
ACACCAAAGT GCAACATCCC ACCAGCACCA AGACATGCTT TTGAGATATT TAGAAGGTTC 
TACTTAGCCA AACACAGTGG TCGACAGCTC ACACTCCAGC ATCACATGGG TTCTGCAGAT 
CTCAATGCCA CCTTTTATGG TCCAGTTAAA AAGGAAGATG GATCTGAGGT TGGTGTTGGC 
GGTGCACAAG TAACTGGTTC TAATACACGG AAGCACATAC TGCAAGTCTC CACTTTCCAG 
ATGACCATAT TAATGCTTTT TAATAATAGA GAGAAGTACA CATTTGAGGA AATTCAACAA 
GAGACAGATA TCCCTGAAAG AGAACTTGTT AGAGCCCTCC AGTCCCTCGC CTGTGGTAAA 
CCAACACAGC GGGTCCTCAC AAAAGAACCC AAGTCCAAGG AGATAGAAAG TGGCCACATA 
TTTACAGTTA ATGATCAATT CACATCTAAA CTACACAGAG TCAAGATTCA AACAGTTGCA 
GCCAAACAAG GTGAATCCGA CCCAGAAAGG AAAGAAACAA GACAGAAAGT AGATGATGAC 
AGAAAACATG AGATAGAAGC TGCTATAGTG CGAATAATGA AGTCTAGGAA GAAGATGCAG 
CACAATGTTT TAGTAGCAGA GGTAACTCAG CAACTGAAGG CTCGATTCTT ACCAAGTCCA 
GTTGTTATTA AGAAACGTAT TGAAGGACTT ATTGAGAGAG AATATTTGGC ACGAACACCT 
GAGGATCGCA AAGTATACAC ATATGTAGCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( XM_006496498.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496561.1 Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu27774
Clone ID Related Accession (Same CDS sequence)	XM_006496498.3 , XM_006496498.4
Accession Version	XM_006496498.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006496498.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATTCA AGAAATCCAG CGTGCGAGAA GATGTACTAA ATTCATTGAA TAACAACTTT 
CTTCAAACAC TAAATCAAGC TTGGAATGAT CATCAAACAG CCATGGTGAT GATTAGAGAC 
ATATTAATGT ATATGGACCG TGTATATGTA CAACAGAATA ATGTAGAAAA TGTCTACAAT 
TTGGGATTAA TAATTTTTCG AGATCAAGTT GTACGGTATG GGTGTATTAG GGATCATCTT 
CGGCAAACTT TATTGGATAT GATTGCCAGA GAGCGGAAAG GAGAAGTTGT AGACAGAGGA 
GCAATAAGAA ATGCTTGCCA GATGTTAATG ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT 
GAGGAAGATT TTGAGGCTCC GTTTTTGGAA ATGTCTGCAG AATTTTTTCA GATGGAAAGC 
CAGAAATTTT TAGCAGAAAA CAGTGCTTCA GTATATATAA AGAAAGTAGA AGCTAGGATT 
AATGAGGAAA TAGAGCGGGT GATGCACTGC CTTGACAAAT CCACAGAAGA GCCTATTGTG 
AAGGTGGTGG AGAGGGAACT CATTTCCAAG CACATGAAGA CTATTGTAGA AATGGAAAAT 
TCTGGGCTAG TACATATGCT GAAAAATGGA AAGACAGAAG ACCTTGCTTG CATGTACAAA 
TTATTTAGTC GTGTGCCAAA TGGTTTGAAG ACCATGTGTG AATGTATGAG TTGTTATTTG 
AGGGAACAAG GAAAAGCCCT TGTTTCTGAG GAAGGAGAAG GGAAGAATCC TGTTGACTAT 
ATCCAGGGCT TATTGGATCT AAAGAGTAGG TTTGATCGCT TCCTCCAAGA ATCCTTCAAT 
AATGACCGGC TCTTTAAACA GACTATTGCT GGGGACTTCG AGTATTTCTT AAACCTCAAC 
TCTAGGTCTC CTGAATACCT CTCATTATTT ATTGATGATA AACTGAAAAA GGGAGTCAAA 
GGGCTAACAG AACAAGAAGT AGAAACAATA TTGGATAAGG CAATGGTCCT TTTTAGGTTT 
ATGCAAGAAA AAGATGTATT TGAACGTTAT TATAAACAAC ACCTGGCAAG AAGACTGCTC 
ACAAATAAAA GTGTTTCTGA TGACTCTGAG AAAAATATGA TTTCTAAATT AAAGACTGAG 
TGTGGATGTC AATTCACATC GAAACTGGAA GGAATGTTTA GGGATATGAG CATCTCAAAC 
ACAACTATGG ATGAGTTCAG GCAACATCTA CAGGCAACGG GGGTCTCTTT AGGTGGTGTT 
GATCTCACAG TCCGGGTTCT CACAACGGGA TATTGGCCTA CTCAGTCAGC CACACCAAAG 
TGCAACATCC CACCAGCACC AAGACATGCT TTTGAGATAT TTAGAAGGTT CTACTTAGCC 
AAACACAGTG GTCGACAGCT CACACTCCAG CATCACATGG GTTCTGCAGA TCTCAATGCC 
ACCTTTTATG GTCCAGTTAA AAAGGAAGAT GGATCTGAGG TTGGTGTTGG CGGTGCACAA 
GTAACTGGTT CTAATACACG GAAGCACATA CTGCAAGTCT CCACTTTCCA GATGACCATA 
TTAATGCTTT TTAATAATAG AGAGAAGTAC ACATTTGAGG AAATTCAACA AGAGACAGAT 
ATCCCTGAAA GAGAACTTGT TAGAGCCCTC CAGTCCCTCG CCTGTGGTAA ACCAACACAG 
CGGGTCCTCA CAAAAGAACC CAAGTCCAAG GAGATAGAAA GTGGCCACAT ATTTACAGTT 
AATGATCAAT TCACATCTAA ACTACACAGA GTCAAGATTC AAACAGTTGC AGCCAAACAA 
GGTGAATCCG ACCCAGAAAG GAAAGAAACA AGACAGAAAG TAGATGATGA CAGAAAACAT 
GAGATAGAAG CTGCTATAGT GCGAATAATG AAGTCTAGGA AGAAGATGCA GCACAATGTT 
TTAGTAGCAG AGGTAACTCA GCAACTGAAG GCTCGATTCT TACCAAGTCC AGTTGTTATT 
AAGAAACGTA TTGAAGGACT TATTGAGAGA GAATATTTGG CACGAACACC TGAGGATCGC 
AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496561.1
CDS	268..2331
Translation	MQFKKSSVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	XM_006496498.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006496498.3

ORF Insert Sequence:

ATGCAATTCA AGAAATCCAG CGTGCGAGAA GATGTACTAA ATTCATTGAA TAACAACTTT 
CTTCAAACAC TAAATCAAGC TTGGAATGAT CATCAAACAG CCATGGTGAT GATTAGAGAC 
ATATTAATGT ATATGGACCG TGTATATGTA CAACAGAATA ATGTAGAAAA TGTCTACAAT 
TTGGGATTAA TAATTTTTCG AGATCAAGTT GTACGGTATG GGTGTATTAG GGATCATCTT 
CGGCAAACTT TATTGGATAT GATTGCCAGA GAGCGGAAAG GAGAAGTTGT AGACAGAGGA 
GCAATAAGAA ATGCTTGCCA GATGTTAATG ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT 
GAGGAAGATT TTGAGGCTCC GTTTTTGGAA ATGTCTGCAG AATTTTTTCA GATGGAAAGC 
CAGAAATTTT TAGCAGAAAA CAGTGCTTCA GTATATATAA AGAAAGTAGA AGCTAGGATT 
AATGAGGAAA TAGAGCGGGT GATGCACTGC CTTGACAAAT CCACAGAAGA GCCTATTGTG 
AAGGTGGTGG AGAGGGAACT CATTTCCAAG CACATGAAGA CTATTGTAGA AATGGAAAAT 
TCTGGGCTAG TACATATGCT GAAAAATGGA AAGACAGAAG ACCTTGCTTG CATGTACAAA 
TTATTTAGTC GTGTGCCAAA TGGTTTGAAG ACCATGTGTG AATGTATGAG TTGTTATTTG 
AGGGAACAAG GAAAAGCCCT TGTTTCTGAG GAAGGAGAAG GGAAGAATCC TGTTGACTAT 
ATCCAGGGCT TATTGGATCT AAAGAGTAGG TTTGATCGCT TCCTCCAAGA ATCCTTCAAT 
AATGACCGGC TCTTTAAACA GACTATTGCT GGGGACTTCG AGTATTTCTT AAACCTCAAC 
TCTAGGTCTC CTGAATACCT CTCATTATTT ATTGATGATA AACTGAAAAA GGGAGTCAAA 
GGGCTAACAG AACAAGAAGT AGAAACAATA TTGGATAAGG CAATGGTCCT TTTTAGGTTT 
ATGCAAGAAA AAGATGTATT TGAACGTTAT TATAAACAAC ACCTGGCAAG AAGACTGCTC 
ACAAATAAAA GTGTTTCTGA TGACTCTGAG AAAAATATGA TTTCTAAATT AAAGACTGAG 
TGTGGATGTC AATTCACATC GAAACTGGAA GGAATGTTTA GGGATATGAG CATCTCAAAC 
ACAACTATGG ATGAGTTCAG GCAACATCTA CAGGCAACGG GGGTCTCTTT AGGTGGTGTT 
GATCTCACAG TCCGGGTTCT CACAACGGGA TATTGGCCTA CTCAGTCAGC CACACCAAAG 
TGCAACATCC CACCAGCACC AAGACATGCT TTTGAGATAT TTAGAAGGTT CTACTTAGCC 
AAACACAGTG GTCGACAGCT CACACTCCAG CATCACATGG GTTCTGCAGA TCTCAATGCC 
ACCTTTTATG GTCCAGTTAA AAAGGAAGAT GGATCTGAGG TTGGTGTTGG CGGTGCACAA 
GTAACTGGTT CTAATACACG GAAGCACATA CTGCAAGTCT CCACTTTCCA GATGACCATA 
TTAATGCTTT TTAATAATAG AGAGAAGTAC ACATTTGAGG AAATTCAACA AGAGACAGAT 
ATCCCTGAAA GAGAACTTGT TAGAGCCCTC CAGTCCCTCG CCTGTGGTAA ACCAACACAG 
CGGGTCCTCA CAAAAGAACC CAAGTCCAAG GAGATAGAAA GTGGCCACAT ATTTACAGTT 
AATGATCAAT TCACATCTAA ACTACACAGA GTCAAGATTC AAACAGTTGC AGCCAAACAA 
GGTGAATCCG ACCCAGAAAG GAAAGAAACA AGACAGAAAG TAGATGATGA CAGAAAACAT 
GAGATAGAAG CTGCTATAGT GCGAATAATG AAGTCTAGGA AGAAGATGCA GCACAATGTT 
TTAGTAGCAG AGGTAACTCA GCAACTGAAG GCTCGATTCT TACCAAGTCC AGTTGTTATT 
AAGAAACGTA TTGAAGGACT TATTGAGAGA GAATATTTGG CACGAACACC TGAGGATCGC 
AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( XM_006496498.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496561.1 Mus musculus cullin 3 (Cul3), transcript variant X3, mRNA.

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CloneID	OMu27774
Clone ID Related Accession (Same CDS sequence)	XM_006496498.3 , XM_006496498.4
Accession Version	XM_006496498.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006496498.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATTCA AGAAATCCAG CGTGCGAGAA GATGTACTAA ATTCATTGAA TAACAACTTT 
CTTCAAACAC TAAATCAAGC TTGGAATGAT CATCAAACAG CCATGGTGAT GATTAGAGAC 
ATATTAATGT ATATGGACCG TGTATATGTA CAACAGAATA ATGTAGAAAA TGTCTACAAT 
TTGGGATTAA TAATTTTTCG AGATCAAGTT GTACGGTATG GGTGTATTAG GGATCATCTT 
CGGCAAACTT TATTGGATAT GATTGCCAGA GAGCGGAAAG GAGAAGTTGT AGACAGAGGA 
GCAATAAGAA ATGCTTGCCA GATGTTAATG ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT 
GAGGAAGATT TTGAGGCTCC GTTTTTGGAA ATGTCTGCAG AATTTTTTCA GATGGAAAGC 
CAGAAATTTT TAGCAGAAAA CAGTGCTTCA GTATATATAA AGAAAGTAGA AGCTAGGATT 
AATGAGGAAA TAGAGCGGGT GATGCACTGC CTTGACAAAT CCACAGAAGA GCCTATTGTG 
AAGGTGGTGG AGAGGGAACT CATTTCCAAG CACATGAAGA CTATTGTAGA AATGGAAAAT 
TCTGGGCTAG TACATATGCT GAAAAATGGA AAGACAGAAG ACCTTGCTTG CATGTACAAA 
TTATTTAGTC GTGTGCCAAA TGGTTTGAAG ACCATGTGTG AATGTATGAG TTGTTATTTG 
AGGGAACAAG GAAAAGCCCT TGTTTCTGAG GAAGGAGAAG GGAAGAATCC TGTTGACTAT 
ATCCAGGGCT TATTGGATCT AAAGAGTAGG TTTGATCGCT TCCTCCAAGA ATCCTTCAAT 
AATGACCGGC TCTTTAAACA GACTATTGCT GGGGACTTCG AGTATTTCTT AAACCTCAAC 
TCTAGGTCTC CTGAATACCT CTCATTATTT ATTGATGATA AACTGAAAAA GGGAGTCAAA 
GGGCTAACAG AACAAGAAGT AGAAACAATA TTGGATAAGG CAATGGTCCT TTTTAGGTTT 
ATGCAAGAAA AAGATGTATT TGAACGTTAT TATAAACAAC ACCTGGCAAG AAGACTGCTC 
ACAAATAAAA GTGTTTCTGA TGACTCTGAG AAAAATATGA TTTCTAAATT AAAGACTGAG 
TGTGGATGTC AATTCACATC GAAACTGGAA GGAATGTTTA GGGATATGAG CATCTCAAAC 
ACAACTATGG ATGAGTTCAG GCAACATCTA CAGGCAACGG GGGTCTCTTT AGGTGGTGTT 
GATCTCACAG TCCGGGTTCT CACAACGGGA TATTGGCCTA CTCAGTCAGC CACACCAAAG 
TGCAACATCC CACCAGCACC AAGACATGCT TTTGAGATAT TTAGAAGGTT CTACTTAGCC 
AAACACAGTG GTCGACAGCT CACACTCCAG CATCACATGG GTTCTGCAGA TCTCAATGCC 
ACCTTTTATG GTCCAGTTAA AAAGGAAGAT GGATCTGAGG TTGGTGTTGG CGGTGCACAA 
GTAACTGGTT CTAATACACG GAAGCACATA CTGCAAGTCT CCACTTTCCA GATGACCATA 
TTAATGCTTT TTAATAATAG AGAGAAGTAC ACATTTGAGG AAATTCAACA AGAGACAGAT 
ATCCCTGAAA GAGAACTTGT TAGAGCCCTC CAGTCCCTCG CCTGTGGTAA ACCAACACAG 
CGGGTCCTCA CAAAAGAACC CAAGTCCAAG GAGATAGAAA GTGGCCACAT ATTTACAGTT 
AATGATCAAT TCACATCTAA ACTACACAGA GTCAAGATTC AAACAGTTGC AGCCAAACAA 
GGTGAATCCG ACCCAGAAAG GAAAGAAACA AGACAGAAAG TAGATGATGA CAGAAAACAT 
GAGATAGAAG CTGCTATAGT GCGAATAATG AAGTCTAGGA AGAAGATGCA GCACAATGTT 
TTAGTAGCAG AGGTAACTCA GCAACTGAAG GCTCGATTCT TACCAAGTCC AGTTGTTATT 
AAGAAACGTA TTGAAGGACT TATTGAGAGA GAATATTTGG CACGAACACC TGAGGATCGC 
AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496561.1
CDS	275..2338
Translation	MQFKKSSVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	XM_006496498.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006496498.4

ORF Insert Sequence:

ATGCAATTCA AGAAATCCAG CGTGCGAGAA GATGTACTAA ATTCATTGAA TAACAACTTT 
CTTCAAACAC TAAATCAAGC TTGGAATGAT CATCAAACAG CCATGGTGAT GATTAGAGAC 
ATATTAATGT ATATGGACCG TGTATATGTA CAACAGAATA ATGTAGAAAA TGTCTACAAT 
TTGGGATTAA TAATTTTTCG AGATCAAGTT GTACGGTATG GGTGTATTAG GGATCATCTT 
CGGCAAACTT TATTGGATAT GATTGCCAGA GAGCGGAAAG GAGAAGTTGT AGACAGAGGA 
GCAATAAGAA ATGCTTGCCA GATGTTAATG ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT 
GAGGAAGATT TTGAGGCTCC GTTTTTGGAA ATGTCTGCAG AATTTTTTCA GATGGAAAGC 
CAGAAATTTT TAGCAGAAAA CAGTGCTTCA GTATATATAA AGAAAGTAGA AGCTAGGATT 
AATGAGGAAA TAGAGCGGGT GATGCACTGC CTTGACAAAT CCACAGAAGA GCCTATTGTG 
AAGGTGGTGG AGAGGGAACT CATTTCCAAG CACATGAAGA CTATTGTAGA AATGGAAAAT 
TCTGGGCTAG TACATATGCT GAAAAATGGA AAGACAGAAG ACCTTGCTTG CATGTACAAA 
TTATTTAGTC GTGTGCCAAA TGGTTTGAAG ACCATGTGTG AATGTATGAG TTGTTATTTG 
AGGGAACAAG GAAAAGCCCT TGTTTCTGAG GAAGGAGAAG GGAAGAATCC TGTTGACTAT 
ATCCAGGGCT TATTGGATCT AAAGAGTAGG TTTGATCGCT TCCTCCAAGA ATCCTTCAAT 
AATGACCGGC TCTTTAAACA GACTATTGCT GGGGACTTCG AGTATTTCTT AAACCTCAAC 
TCTAGGTCTC CTGAATACCT CTCATTATTT ATTGATGATA AACTGAAAAA GGGAGTCAAA 
GGGCTAACAG AACAAGAAGT AGAAACAATA TTGGATAAGG CAATGGTCCT TTTTAGGTTT 
ATGCAAGAAA AAGATGTATT TGAACGTTAT TATAAACAAC ACCTGGCAAG AAGACTGCTC 
ACAAATAAAA GTGTTTCTGA TGACTCTGAG AAAAATATGA TTTCTAAATT AAAGACTGAG 
TGTGGATGTC AATTCACATC GAAACTGGAA GGAATGTTTA GGGATATGAG CATCTCAAAC 
ACAACTATGG ATGAGTTCAG GCAACATCTA CAGGCAACGG GGGTCTCTTT AGGTGGTGTT 
GATCTCACAG TCCGGGTTCT CACAACGGGA TATTGGCCTA CTCAGTCAGC CACACCAAAG 
TGCAACATCC CACCAGCACC AAGACATGCT TTTGAGATAT TTAGAAGGTT CTACTTAGCC 
AAACACAGTG GTCGACAGCT CACACTCCAG CATCACATGG GTTCTGCAGA TCTCAATGCC 
ACCTTTTATG GTCCAGTTAA AAAGGAAGAT GGATCTGAGG TTGGTGTTGG CGGTGCACAA 
GTAACTGGTT CTAATACACG GAAGCACATA CTGCAAGTCT CCACTTTCCA GATGACCATA 
TTAATGCTTT TTAATAATAG AGAGAAGTAC ACATTTGAGG AAATTCAACA AGAGACAGAT 
ATCCCTGAAA GAGAACTTGT TAGAGCCCTC CAGTCCCTCG CCTGTGGTAA ACCAACACAG 
CGGGTCCTCA CAAAAGAACC CAAGTCCAAG GAGATAGAAA GTGGCCACAT ATTTACAGTT 
AATGATCAAT TCACATCTAA ACTACACAGA GTCAAGATTC AAACAGTTGC AGCCAAACAA 
GGTGAATCCG ACCCAGAAAG GAAAGAAACA AGACAGAAAG TAGATGATGA CAGAAAACAT 
GAGATAGAAG CTGCTATAGT GCGAATAATG AAGTCTAGGA AGAAGATGCA GCACAATGTT 
TTAGTAGCAG AGGTAACTCA GCAACTGAAG GCTCGATTCT TACCAAGTCC AGTTGTTATT 
AAGAAACGTA TTGAAGGACT TATTGAGAGA GAATATTTGG CACGAACACC TGAGGATCGC 
AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul3 ( XM_030254438.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110298.1 Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69223
Clone ID Related Accession (Same CDS sequence)	NM_001313728.1 , XM_030254438.1
Accession Version	XM_030254438.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	cullin-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTGTC CTCAGTGCAT CACATCAGGA GGCACATGCT GTCAGTTTAT CCCATTATTG 
GTGATGTTAA CTTTGATCAC TTGGTGTCCG CCAGATTTCT TCACTGTAAA GGTGCGAGAA 
GATGTACTAA ATTCATTGAA TAACAACTTT CTTCAAACAC TAAATCAAGC TTGGAATGAT 
CATCAAACAG CCATGGTGAT GATTAGAGAC ATATTAATGT ATATGGACCG TGTATATGTA 
CAACAGAATA ATGTAGAAAA TGTCTACAAT TTGGGATTAA TAATTTTTCG AGATCAAGTT 
GTACGGTATG GGTGTATTAG GGATCATCTT CGGCAAACTT TATTGGATAT GATTGCCAGA 
GAGCGGAAAG GAGAAGTTGT AGACAGAGGA GCAATAAGAA ATGCTTGCCA GATGTTAATG 
ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT GAGGAAGATT TTGAGGCTCC GTTTTTGGAA 
ATGTCTGCAG AATTTTTTCA GATGGAAAGC CAGAAATTTT TAGCAGAAAA CAGTGCTTCA 
GTATATATAA AGAAAGTAGA AGCTAGGATT AATGAGGAAA TAGAGCGGGT GATGCACTGC 
CTTGACAAAT CCACAGAAGA GCCTATTGTG AAGGTGGTGG AGAGGGAACT CATTTCCAAG 
CACATGAAGA CTATTGTAGA AATGGAAAAT TCTGGGCTAG TACATATGCT GAAAAATGGA 
AAGACAGAAG ACCTTGCTTG CATGTACAAA TTATTTAGTC GTGTGCCAAA TGGTTTGAAG 
ACCATGTGTG AATGTATGAG TTGTTATTTG AGGGAACAAG GAAAAGCCCT TGTTTCTGAG 
GAAGGAGAAG GGAAGAATCC TGTTGACTAT ATCCAGGGCT TATTGGATCT AAAGAGTAGG 
TTTGATCGCT TCCTCCAAGA ATCCTTCAAT AATGACCGGC TCTTTAAACA GACTATTGCT 
GGGGACTTCG AGTATTTCTT AAACCTCAAC TCTAGGTCTC CTGAATACCT CTCATTATTT 
ATTGATGATA AACTGAAAAA GGGAGTCAAA GGGCTAACAG AACAAGAAGT AGAAACAATA 
TTGGATAAGG CAATGGTCCT TTTTAGGTTT ATGCAAGAAA AAGATGTATT TGAACGTTAT 
TATAAACAAC ACCTGGCAAG AAGACTGCTC ACAAATAAAA GTGTTTCTGA TGACTCTGAG 
AAAAATATGA TTTCTAAATT AAAGACTGAG TGTGGATGTC AATTCACATC GAAACTGGAA 
GGAATGTTTA GGGATATGAG CATCTCAAAC ACAACTATGG ATGAGTTCAG GCAACATCTA 
CAGGCAACGG GGGTCTCTTT AGGTGGTGTT GATCTCACAG TCCGGGTTCT CACAACGGGA 
TATTGGCCTA CTCAGTCAGC CACACCAAAG TGCAACATCC CACCAGCACC AAGACATGCT 
TTTGAGATAT TTAGAAGGTT CTACTTAGCC AAACACAGTG GTCGACAGCT CACACTCCAG 
CATCACATGG GTTCTGCAGA TCTCAATGCC ACCTTTTATG GTCCAGTTAA AAAGGAAGAT 
GGATCTGAGG TTGGTGTTGG CGGTGCACAA GTAACTGGTT CTAATACACG GAAGCACATA 
CTGCAAGTCT CCACTTTCCA GATGACCATA TTAATGCTTT TTAATAATAG AGAGAAGTAC 
ACATTTGAGG AAATTCAACA AGAGACAGAT ATCCCTGAAA GAGAACTTGT TAGAGCCCTC 
CAGTCCCTCG CCTGTGGTAA ACCAACACAG CGGGTCCTCA CAAAAGAACC CAAGTCCAAG 
GAGATAGAAA GTGGCCACAT ATTTACAGTT AATGATCAAT TCACATCTAA ACTACACAGA 
GTCAAGATTC AAACAGTTGC AGCCAAACAA GGTGAATCCG ACCCAGAAAG GAAAGAAACA 
AGACAGAAAG TAGATGATGA CAGAAAACAT GAGATAGAAG CTGCTATAGT GCGAATAATG 
AAGTCTAGGA AGAAGATGCA GCACAATGTT TTAGTAGCAG AGGTAACTCA GCAACTGAAG 
GCTCGATTCT TACCAAGTCC AGTTGTTATT AAGAAACGTA TTGAAGGACT TATTGAGAGA 
GAATATTTGG CACGAACACC TGAGGATCGC AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110298.1
CDS	181..2334
Translation	MLCPQCITSGGTCCQFIPLLVMLTLITWCPPDFFTVKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA

Target ORF information:

RefSeq Version	XM_030254438.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cullin 3 (Cul3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254438.1

ORF Insert Sequence:

ATGTTGTGTC CTCAGTGCAT CACATCAGGA GGCACATGCT GTCAGTTTAT CCCATTATTG 
GTGATGTTAA CTTTGATCAC TTGGTGTCCG CCAGATTTCT TCACTGTAAA GGTGCGAGAA 
GATGTACTAA ATTCATTGAA TAACAACTTT CTTCAAACAC TAAATCAAGC TTGGAATGAT 
CATCAAACAG CCATGGTGAT GATTAGAGAC ATATTAATGT ATATGGACCG TGTATATGTA 
CAACAGAATA ATGTAGAAAA TGTCTACAAT TTGGGATTAA TAATTTTTCG AGATCAAGTT 
GTACGGTATG GGTGTATTAG GGATCATCTT CGGCAAACTT TATTGGATAT GATTGCCAGA 
GAGCGGAAAG GAGAAGTTGT AGACAGAGGA GCAATAAGAA ATGCTTGCCA GATGTTAATG 
ATTTTAGGTC TTGAAGGAAG ATCAGTCTAT GAGGAAGATT TTGAGGCTCC GTTTTTGGAA 
ATGTCTGCAG AATTTTTTCA GATGGAAAGC CAGAAATTTT TAGCAGAAAA CAGTGCTTCA 
GTATATATAA AGAAAGTAGA AGCTAGGATT AATGAGGAAA TAGAGCGGGT GATGCACTGC 
CTTGACAAAT CCACAGAAGA GCCTATTGTG AAGGTGGTGG AGAGGGAACT CATTTCCAAG 
CACATGAAGA CTATTGTAGA AATGGAAAAT TCTGGGCTAG TACATATGCT GAAAAATGGA 
AAGACAGAAG ACCTTGCTTG CATGTACAAA TTATTTAGTC GTGTGCCAAA TGGTTTGAAG 
ACCATGTGTG AATGTATGAG TTGTTATTTG AGGGAACAAG GAAAAGCCCT TGTTTCTGAG 
GAAGGAGAAG GGAAGAATCC TGTTGACTAT ATCCAGGGCT TATTGGATCT AAAGAGTAGG 
TTTGATCGCT TCCTCCAAGA ATCCTTCAAT AATGACCGGC TCTTTAAACA GACTATTGCT 
GGGGACTTCG AGTATTTCTT AAACCTCAAC TCTAGGTCTC CTGAATACCT CTCATTATTT 
ATTGATGATA AACTGAAAAA GGGAGTCAAA GGGCTAACAG AACAAGAAGT AGAAACAATA 
TTGGATAAGG CAATGGTCCT TTTTAGGTTT ATGCAAGAAA AAGATGTATT TGAACGTTAT 
TATAAACAAC ACCTGGCAAG AAGACTGCTC ACAAATAAAA GTGTTTCTGA TGACTCTGAG 
AAAAATATGA TTTCTAAATT AAAGACTGAG TGTGGATGTC AATTCACATC GAAACTGGAA 
GGAATGTTTA GGGATATGAG CATCTCAAAC ACAACTATGG ATGAGTTCAG GCAACATCTA 
CAGGCAACGG GGGTCTCTTT AGGTGGTGTT GATCTCACAG TCCGGGTTCT CACAACGGGA 
TATTGGCCTA CTCAGTCAGC CACACCAAAG TGCAACATCC CACCAGCACC AAGACATGCT 
TTTGAGATAT TTAGAAGGTT CTACTTAGCC AAACACAGTG GTCGACAGCT CACACTCCAG 
CATCACATGG GTTCTGCAGA TCTCAATGCC ACCTTTTATG GTCCAGTTAA AAAGGAAGAT 
GGATCTGAGG TTGGTGTTGG CGGTGCACAA GTAACTGGTT CTAATACACG GAAGCACATA 
CTGCAAGTCT CCACTTTCCA GATGACCATA TTAATGCTTT TTAATAATAG AGAGAAGTAC 
ACATTTGAGG AAATTCAACA AGAGACAGAT ATCCCTGAAA GAGAACTTGT TAGAGCCCTC 
CAGTCCCTCG CCTGTGGTAA ACCAACACAG CGGGTCCTCA CAAAAGAACC CAAGTCCAAG 
GAGATAGAAA GTGGCCACAT ATTTACAGTT AATGATCAAT TCACATCTAA ACTACACAGA 
GTCAAGATTC AAACAGTTGC AGCCAAACAA GGTGAATCCG ACCCAGAAAG GAAAGAAACA 
AGACAGAAAG TAGATGATGA CAGAAAACAT GAGATAGAAG CTGCTATAGT GCGAATAATG 
AAGTCTAGGA AGAAGATGCA GCACAATGTT TTAGTAGCAG AGGTAACTCA GCAACTGAAG 
GCTCGATTCT TACCAAGTCC AGTTGTTATT AAGAAACGTA TTGAAGGACT TATTGAGAGA 
GAATATTTGG CACGAACACC TGAGGATCGC AAAGTATACA CATATGTAGC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Scientific reports9(1)4596(2019 Mar)
Saritas T,Cuevas CA,Ferdaus MZ,Kuppe C,Kramann R,Moeller MJ,Floege J,Singer JD,McCormick JA

Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
Clinical and experimental nephrology22(6)1251-1257(2018 Dec)
Yoshida S,Araki Y,Mori T,Sasaki E,Kasagi Y,Isobe K,Susa K,Inoue Y,Bomont P,Okado T,Rai T,Uchida S,Sohara E

Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
Toxicology and applied pharmacology36045-57(2018 12)
McMahon M,Swift SR,Hayes JD

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
American journal of physiology. Renal physiology315(4)F1006-F1018(2018 10)
Cornelius RJ,Zhang C,Erspamer KJ,Agbor LN,Sigmund CD,Singer JD,Yang CL,Ellison DH

Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter.
The Journal of biological chemistry293(27)10574-10589(2018 07)
Raghavan S,Singh NK,Mani AM,Rao GN

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Cul3 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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