Esyt1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Esyt1
Entrez Gene ID	23943
Full Name	extended synaptotagmin-like protein 1
Synonyms	Fam62a,Mbc2,vp115
General protein information	Preferred Names extended synaptotagmin-like protein 1 Names extended synaptotagmin-1 E-Syt1 family with sequence similarity 62 (C2 domain containing), member A membrane-bound C2 domain-containing protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_011843.2	NP_035973.1	extended synaptotagmin-1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	esyt1a	XP_695611.3
Arabidopsis thaliana (thale cress)	SYTA	NP_565495.1
Oryza sativa (rice)	Os09g0538800	NP_001063800.1
Oryza sativa (rice)	Os02g0448400	NP_001046755.1
Homo sapiens (human)	ESYT1	NP_001171725.1
Pan troglodytes (chimpanzee)	ESYT1	XP_509135.2
Macaca mulatta (Rhesus monkey)	ESYT1	XP_001114269.1
Rattus norvegicus (Norway rat)	Esyt1	NP_058945.2
Danio rerio (zebrafish)	esyt1b	XP_699731.6
Xenopus tropicalis (tropical clawed frog)	esyt1	XP_002934579.1
Canis lupus familiaris (dog)	ESYT1	XP_005625706.1
Bos taurus (cattle)	ESYT1	NP_001071411.1
Mus musculus (house mouse)	Esyt1	NP_035973.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.
Tremblay MG, Moss T
Cell cycle (Georgetown, Tex.)15(17)2360-6(2016 Sep)

Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction.
Sclip A, Bacaj T, Giam LR, Südhof TC
PloS one11(6)e0158295(2016)

Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected.
Herdman C, Tremblay MG, Mishra PK, Moss T
Cell cycle (Georgetown, Tex.)13(16)2616-25(2014)

The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes.
Lalioti V, Muruais G, Dinarina A, van Damme J, Vandekerckhove J, Sandoval IV
Proceedings of the National Academy of Sciences of the United States of America106(11)4249-53(2009 Mar)

Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains.
Morris NJ, Ross SA, Neveu JM, Lane WS, Lienhard GE
Biochimica et biophysica acta1431(2)525-30(1999 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Esyt1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Esyt1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08967	NM_011843.2 Latest version!	Mus musculus extended synaptotagmin-like protein 1 (Esyt1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Esyt1 ( NM_011843.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035973.1 Mus musculus extended synaptotagmin-like protein 1 (Esyt1), mRNA.

Price & Availability↑

CloneID	OMu08967
Clone ID Related Accession (Same CDS sequence)	NM_011843.2
Accession Version	NM_011843.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Mus musculus(house mouse)
Product	extended synaptotagmin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC170752.2. On Nov 17, 2006 this sequence version replaced NM_011843.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC011482.1, AK088421.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCACT CCCCTGAAGA GGGCGCCAGC CCCGAGCCGT CAGGGCAGCC CCCTGCCACG 
GACTCCACGC GGGACGGGGG CTCCGGGGTC CCACCTGCCG GCCCAGGTGC GGCGAGCGAG 
GCCCTGGCGG TGCTGACTTC CTTCGGGCGC CGCTTGTTGG TGCTGGTGCC GGTGTACCTG 
GCAGGGGCAG CGGGTCTTAG CGTAGGTTTC GTGCTTTTCG GCCTCGCCCT GTACTTGGGC 
TGGCGCCGGG TCCGCGATGG GAAAGAACGG AGCCTGAGGG CAGCGAGGCA GCTGCTGGAT 
GACGAGGAGC GGATCACCGC AGAGACGCTT TATATGAGCC ACCGGGAACT ACCTGCCTGG 
GTCAGCTTCC CAGATGTGGA AAAGGCCGAA TGGCTGAACA AGATCGTGGC TCAGGTGTGG 
CCCTTCCTAG GCCAGTATAT GGAGAAGCTT CTGGCGGAGA CAGTGGCCCC AGCTGTCCGG 
GGAGCTAACC CTCATCTGCA GACATTCACA TTCACACGTG TGGAGCTGGG TGAAAAGCCA 
TTACGAATCA TTGGCGTCAA AGTTCACCCT AGTCAGAGGA AAGATCAGAT TCTGTTGGAC 
TTGAATGTCA GCTATGTAGG TGATGTACAG ATTGACGTGG AGGTGAAGAA ATATTTCTGC 
AAAGCTGGAG TCAAGGGCAT GCAGCTCCAT GGTGTCTTGC GAGTGATTCT TGAGCCACTC 
ACAGGGGACC TTCCTATCGT GGGGGCTGTG TCCATGTTCT TTATCAAACG CCCGACGCTT 
GACATCAACT GGACAGGGAT GACCAACCTG CTAGATATCC CAGGACTTAG CTCACTCTCT 
GACACCATGA TCATGGACTC CATTGCTGCC TTCCTCGTGC TCCCTAACCG ACTGTTGGTG 
CCCCTTGTGC CCGACCTTCA AGATGTGGCC CAGCTGCGGT CCCCACTACC CAGGGGCATT 
ATCCGGATTC ACCTGCTGGC AGCCCGAGGT CTGAGTTCCA AGGACAAGTA TGTGAAAGGC 
CTGATTGAGG GCAAATCGGA TCCCTACGCG CTCGTCCGTG TGGGCACCCA GACGTTCTGC 
AGCCGTGTCA TAGATGAGGA GCTCAACCCT CACTGGGGAG AGACATATGA GGTGATAGTC 
CACGAGGTTC CAGGACAGGA GATCGAGGTG GAGGTATTTG ACAAAGATCC AGATAAAGAT 
GATTTTCTGG GAAGAATGAA GCTGGACGTG GGGAAGGTAT TACAGGCTGG AGTCCTGGAT 
AATTGGTACC CTCTGCAAGG CGGGCAAGGC CAAGTTCACT TGAGACTAGA ATGGCTATCA 
CTCCTGCCAG ATGCAGAGAA GCTGGATCAG GTCCTGCAGT GGAATCGGGG CATCACTTCT 
CGGCCAGAGC CCCCATCGGC TGCCATCCTC GTTGTCTACT TGGACCGAGC CCAGGACCTT 
CCTCTGAAGA AAGGCAACAA GGAACCCAAC CCCATGGTGC AACTATCAGT TCAGGATGTG 
ACCCGGGAGA GCAAGGCTAC CTACAGCACC AACAGCCCGG TGTGGGAAGA GGCTTTCCGG 
TTTTTCCTGC AGGACCCTCG AAGCCAGGAG CTTGATGTAC AGGTGAAGGA CGACTCCCGA 
GCCCTGACTT TAGGGGCCCT GACTCTCCCT CTTGCGCGCC TGTTGACTGC CTCTGAACTC 
ACCCTGGACC AGTGGTTCCA GCTCAGCAGC TCAGGCCCAA ACTCCAGGCT CTACATGAAA 
CTGGTCATGC GGATCTTATA CTTAGATTAC TCGGAAATCC GCTTCCCCAC TGTGCCTGGT 
GCCCAGGACT GGGACCGTGA GAGCCTAGAG ACAGGCAGCA GTGTGGATGC CCCACCTCGG 
CCCTATCACA CAACCCCTAA CAGCCACTTT GGGACTGAGA ATGTTCTTCG GATCCATGTA 
TTAGAAGCGC AGGACCTAAT TGCCAAAGAC CGTTTCTTGG GAGGCCTGGT GAAGGGCAAA 
TCAGACCCCT ACGTCAAACT AAAGGTGGCA GGAAAAAGTT TCCGGACCCA TGTTGTTCGG 
GAAGATCTCA ATCCCCGCTG GAATGAGGTT TTTGAGGTGA TTGTCACATC AATCCCTGGC 
CAAGAGCTTG AGATTGAGGT CTTTGATAAG GACTTGGACA AGGATGACTT TTTGGGCAGG 
TATAAAGTGA GTCTCACCAC AGTGCTCAAC AGTGGCTTTC TTGATGAGTG GCTGACCCTG 
GAGGATGTCC CATCCGGGCG CCTGCACTTG CGCCTGGAGC GTCTGACCCC TAGACCGACT 
GCTGCTGAGT TAGAGGAGGT GCTGCAGGTG AACAGCCTGA TCCAGACTCA GAAGAGTTCA 
GAGCTGGCAG CAGCCCTGCT GTCCGTCTTC CTGGAGCGGG CAGAAGATCT GCCGCTCCGA 
AAAGGTACCA AGCCTCCCAG CCCTTACGCT ACTATCACCG TGGGAGAGAC TTCCCATAAA 
ACCAAGACTG TCTCCCAATC TTCGGCCCCT GTCTGGGAGG AGAGTGCCTC TTTTCTCATC 
AGGAAGCCAC ACGCTGAGAG CCTGGAGCTG CAGGTTCGGG GTGAAGGGAC CGGCACCCTG 
GGCTCTGTAT CCCTTCCTCT CTCTGAGCTC CTCCAGGAGG ACCAGCTCTG CCTGGACCAC 
TGGTTTGCAC TCAGTGGTCA GGGCCAGGTG CTGATGAGAG CGCAGCTTGG GATCCTGGTA 
TCTCAGCACT CGGGAGTGGA AGCCCACAGC CACAGCTACA GCCACAGTCA CAGCTCCTCC 
TCGCTCAATG ACGAACCTGA GGCCTTAGGG GGACCCACTC ACCCTGCCTC CCCGGTCCTA 
GAGGTCAGGC ATCGCCTAAC ACATGGTGAC AGTCCCTCTG AGGCTCCCGT TGGGCCCCTG 
GGCCAGGTGA AGCTGACAGT GTGGTACCAC AGCGACGAAC AAAAGCTGAT CAGCATTATT 
CACAGCTGCC GGGCCCTTCG ACAAAATGGA CGTGATCTCC CAGACCCCTA TGTGTCAGTG 
TTGCTGCTCC CAGACAAGAA CCGAAGCACC AAGAGGAAGA CCCCGCAGAA GAAGAGGACC 
CTCAATCCTG AGTTCAATGA GCGGTTTGAG TGGGATCTGC CCCTGGATGG GACTCTCAGG 
CGGAAGCTCG ATGTCTCTGT GAAGTCAAAC TCCTCCTTCA TGTCACGAGA GCGTGAGCTT 
CTGGGGAAGG TGCAGCTGGA TCTAGCAGAG ATAGACCTTT CCCAGGGTGC AGCCCAGTGG 
TATGACCTGA TGGATGACAG AGATAAGGGC GGTTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035973.1
CDS	37..3315
Translation	MEHSPEEGASPEPSGQPPATDSTRDGGSGVPPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGANPHLQTFTFTRVELGEKPLRIIGVKVHPSQRKDQILLDLNVSYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLTGDLPIVGAVSMFFIKRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPLQGGQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQWFQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVPGAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALSGQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHGDSPSEAPVGPLGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDLMDDRDKGGS

Target ORF information:

RefSeq Version	NM_011843.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus extended synaptotagmin-like protein 1 (Esyt1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011843.2

ORF Insert Sequence:

ATGGAGCACT CCCCTGAAGA GGGCGCCAGC CCCGAGCCGT CAGGGCAGCC CCCTGCCACG 
GACTCCACGC GGGACGGGGG CTCCGGGGTC CCACCTGCCG GCCCAGGTGC GGCGAGCGAG 
GCCCTGGCGG TGCTGACTTC CTTCGGGCGC CGCTTGTTGG TGCTGGTGCC GGTGTACCTG 
GCAGGGGCAG CGGGTCTTAG CGTAGGTTTC GTGCTTTTCG GCCTCGCCCT GTACTTGGGC 
TGGCGCCGGG TCCGCGATGG GAAAGAACGG AGCCTGAGGG CAGCGAGGCA GCTGCTGGAT 
GACGAGGAGC GGATCACCGC AGAGACGCTT TATATGAGCC ACCGGGAACT ACCTGCCTGG 
GTCAGCTTCC CAGATGTGGA AAAGGCCGAA TGGCTGAACA AGATCGTGGC TCAGGTGTGG 
CCCTTCCTAG GCCAGTATAT GGAGAAGCTT CTGGCGGAGA CAGTGGCCCC AGCTGTCCGG 
GGAGCTAACC CTCATCTGCA GACATTCACA TTCACACGTG TGGAGCTGGG TGAAAAGCCA 
TTACGAATCA TTGGCGTCAA AGTTCACCCT AGTCAGAGGA AAGATCAGAT TCTGTTGGAC 
TTGAATGTCA GCTATGTAGG TGATGTACAG ATTGACGTGG AGGTGAAGAA ATATTTCTGC 
AAAGCTGGAG TCAAGGGCAT GCAGCTCCAT GGTGTCTTGC GAGTGATTCT TGAGCCACTC 
ACAGGGGACC TTCCTATCGT GGGGGCTGTG TCCATGTTCT TTATCAAACG CCCGACGCTT 
GACATCAACT GGACAGGGAT GACCAACCTG CTAGATATCC CAGGACTTAG CTCACTCTCT 
GACACCATGA TCATGGACTC CATTGCTGCC TTCCTCGTGC TCCCTAACCG ACTGTTGGTG 
CCCCTTGTGC CCGACCTTCA AGATGTGGCC CAGCTGCGGT CCCCACTACC CAGGGGCATT 
ATCCGGATTC ACCTGCTGGC AGCCCGAGGT CTGAGTTCCA AGGACAAGTA TGTGAAAGGC 
CTGATTGAGG GCAAATCGGA TCCCTACGCG CTCGTCCGTG TGGGCACCCA GACGTTCTGC 
AGCCGTGTCA TAGATGAGGA GCTCAACCCT CACTGGGGAG AGACATATGA GGTGATAGTC 
CACGAGGTTC CAGGACAGGA GATCGAGGTG GAGGTATTTG ACAAAGATCC AGATAAAGAT 
GATTTTCTGG GAAGAATGAA GCTGGACGTG GGGAAGGTAT TACAGGCTGG AGTCCTGGAT 
AATTGGTACC CTCTGCAAGG CGGGCAAGGC CAAGTTCACT TGAGACTAGA ATGGCTATCA 
CTCCTGCCAG ATGCAGAGAA GCTGGATCAG GTCCTGCAGT GGAATCGGGG CATCACTTCT 
CGGCCAGAGC CCCCATCGGC TGCCATCCTC GTTGTCTACT TGGACCGAGC CCAGGACCTT 
CCTCTGAAGA AAGGCAACAA GGAACCCAAC CCCATGGTGC AACTATCAGT TCAGGATGTG 
ACCCGGGAGA GCAAGGCTAC CTACAGCACC AACAGCCCGG TGTGGGAAGA GGCTTTCCGG 
TTTTTCCTGC AGGACCCTCG AAGCCAGGAG CTTGATGTAC AGGTGAAGGA CGACTCCCGA 
GCCCTGACTT TAGGGGCCCT GACTCTCCCT CTTGCGCGCC TGTTGACTGC CTCTGAACTC 
ACCCTGGACC AGTGGTTCCA GCTCAGCAGC TCAGGCCCAA ACTCCAGGCT CTACATGAAA 
CTGGTCATGC GGATCTTATA CTTAGATTAC TCGGAAATCC GCTTCCCCAC TGTGCCTGGT 
GCCCAGGACT GGGACCGTGA GAGCCTAGAG ACAGGCAGCA GTGTGGATGC CCCACCTCGG 
CCCTATCACA CAACCCCTAA CAGCCACTTT GGGACTGAGA ATGTTCTTCG GATCCATGTA 
TTAGAAGCGC AGGACCTAAT TGCCAAAGAC CGTTTCTTGG GAGGCCTGGT GAAGGGCAAA 
TCAGACCCCT ACGTCAAACT AAAGGTGGCA GGAAAAAGTT TCCGGACCCA TGTTGTTCGG 
GAAGATCTCA ATCCCCGCTG GAATGAGGTT TTTGAGGTGA TTGTCACATC AATCCCTGGC 
CAAGAGCTTG AGATTGAGGT CTTTGATAAG GACTTGGACA AGGATGACTT TTTGGGCAGG 
TATAAAGTGA GTCTCACCAC AGTGCTCAAC AGTGGCTTTC TTGATGAGTG GCTGACCCTG 
GAGGATGTCC CATCCGGGCG CCTGCACTTG CGCCTGGAGC GTCTGACCCC TAGACCGACT 
GCTGCTGAGT TAGAGGAGGT GCTGCAGGTG AACAGCCTGA TCCAGACTCA GAAGAGTTCA 
GAGCTGGCAG CAGCCCTGCT GTCCGTCTTC CTGGAGCGGG CAGAAGATCT GCCGCTCCGA 
AAAGGTACCA AGCCTCCCAG CCCTTACGCT ACTATCACCG TGGGAGAGAC TTCCCATAAA 
ACCAAGACTG TCTCCCAATC TTCGGCCCCT GTCTGGGAGG AGAGTGCCTC TTTTCTCATC 
AGGAAGCCAC ACGCTGAGAG CCTGGAGCTG CAGGTTCGGG GTGAAGGGAC CGGCACCCTG 
GGCTCTGTAT CCCTTCCTCT CTCTGAGCTC CTCCAGGAGG ACCAGCTCTG CCTGGACCAC 
TGGTTTGCAC TCAGTGGTCA GGGCCAGGTG CTGATGAGAG CGCAGCTTGG GATCCTGGTA 
TCTCAGCACT CGGGAGTGGA AGCCCACAGC CACAGCTACA GCCACAGTCA CAGCTCCTCC 
TCGCTCAATG ACGAACCTGA GGCCTTAGGG GGACCCACTC ACCCTGCCTC CCCGGTCCTA 
GAGGTCAGGC ATCGCCTAAC ACATGGTGAC AGTCCCTCTG AGGCTCCCGT TGGGCCCCTG 
GGCCAGGTGA AGCTGACAGT GTGGTACCAC AGCGACGAAC AAAAGCTGAT CAGCATTATT 
CACAGCTGCC GGGCCCTTCG ACAAAATGGA CGTGATCTCC CAGACCCCTA TGTGTCAGTG 
TTGCTGCTCC CAGACAAGAA CCGAAGCACC AAGAGGAAGA CCCCGCAGAA GAAGAGGACC 
CTCAATCCTG AGTTCAATGA GCGGTTTGAG TGGGATCTGC CCCTGGATGG GACTCTCAGG 
CGGAAGCTCG ATGTCTCTGT GAAGTCAAAC TCCTCCTTCA TGTCACGAGA GCGTGAGCTT 
CTGGGGAAGG TGCAGCTGGA TCTAGCAGAG ATAGACCTTT CCCAGGGTGC AGCCCAGTGG 
TATGACCTGA TGGATGACAG AGATAAGGGC GGTTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.
Cell cycle (Georgetown, Tex.)15(17)2360-6(2016 Sep)
Tremblay MG,Moss T

Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction.
PloS one11(6)e0158295(2016)
Sclip A,Bacaj T,Giam LR,Südhof TC

Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected.
Cell cycle (Georgetown, Tex.)13(16)2616-25(2014)
Herdman C,Tremblay MG,Mishra PK,Moss T

The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes.
Proceedings of the National Academy of Sciences of the United States of America106(11)4249-53(2009 Mar)
Lalioti V,Muruais G,Dinarina A,van Damme J,Vandekerckhove J,Sandoval IV

Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains.
Biochimica et biophysica acta1431(2)525-30(1999 May)
Morris NJ,Ross SA,Neveu JM,Lane WS,Lienhard GE

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Esyt1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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