Scn3b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scn3b
Entrez Gene ID	235281
Full Name	sodium channel, voltage-gated, type III, beta
Synonyms	1110001K16Rik,4833414B02Rik,Scnb3
General protein information	Preferred Names sodium channel, voltage-gated, type III, beta Names sodium channel subunit beta-3 brain and heart sodium channel beta 3 subunit
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 A5.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001359700.1	NP_001346629.1	sodium channel subunit beta-3 isoform a precursor
NM_178227.4	NP_839941.1	sodium channel subunit beta-3 isoform a precursor
NM_001286614.1	NP_001273543.1	sodium channel subunit beta-3 isoform b
XM_006510234.1	XP_006510297.1	sodium channel subunit beta-3 isoform X1
NM_001083917.1	NP_001077386.1	sodium channel subunit beta-3 isoform a precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Scn3b	NP_001077386.1
Danio rerio (zebrafish)	scn3b	NP_001074271.1
Homo sapiens (human)	SCN3B	NP_001035241.1
Pan troglodytes (chimpanzee)	SCN3B	XP_522210.3
Rattus norvegicus (Norway rat)	Scn3b	NP_620797.1
Macaca mulatta (Rhesus monkey)	SCN3B	XP_001104555.2
Canis lupus familiaris (dog)	SCN3B	XP_005619701.1
Gallus gallus (chicken)	SCN3B	XP_417884.4
Xenopus tropicalis (tropical clawed frog)	scn3b	NP_001011299.1
Bos taurus (cattle)	SCN3B	NP_001039960.1

Gene Ontology
Bibliography

Related articles in PubMed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.
Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, Miura E, Mazaki E, Ernst SJ, Cao D, Ohtani H, Itohara S, Yanagawa Y, Montal M, Yuzaki M, Inoue Y, Hensch TK, Noebels JL, Yamakawa K
Communications biology196(2018)

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.
Bye CR, Jönsson ME, Björklund A, Parish CL, Thompson LH
Proceedings of the National Academy of Sciences of the United States of America112(15)E1946-55(2015 Apr)

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.
DiTommaso T, Jones LK, Cottle DL, , Gerdin AK, Vancollie VE, Watt FM, Ramirez-Solis R, Bradley A, Steel KP, Sundberg JP, White JK, Smyth IM
PLoS genetics10(10)e1004705(2014 Oct)

Study of the residues involved in the binding of β1 to β3 subunits in the sodium channel.
Liu Q, Jin Y, Wang K, Meng XX, Yang Y, Yang Z, Zhao YS, Zhao MY, Zhang JH
Comptes rendus biologies337(2)73-7(2014 Feb)

Specification of dopaminergic subsets involves interplay of En1 and Pitx3.
Veenvliet JV, Dos Santos MT, Kouwenhoven WM, von Oerthel L, Lim JL, van der Linden AJ, Koerkamp MJ, Holstege FC, Smidt MP
Development (Cambridge, England)140(16)3373-84(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Scn3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scn3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02846	XM_006510234.1 Latest version!	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OMu02846	NM_001083917.1 Latest version!	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu02846	NM_178227.4 Latest version!	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu02846	NM_001359700.1 Latest version!	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$139.30 $199.00
OMu17440	NM_001286614.1 Latest version!	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scn3b ( XM_006510234.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006510297.1 Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu02846
Clone ID Related Accession (Same CDS sequence)	NM_001359700.1 , NM_178227.4 , XM_006510234.1 , NM_001083917.1
Accession Version	XM_006510234.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	sodium channel subunit beta-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006510297.1
CDS	442..1089
Translation	MPAFNRLLPLASLVLIYWVRVCFPVCVEVPSETEAVQGNSMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE

Target ORF information:

RefSeq Version	XM_006510234.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006510234.1

ORF Insert Sequence:

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scn3b ( NM_001359700.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001346629.1 Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu02846
Clone ID Related Accession (Same CDS sequence)	NM_001359700.1 , NM_178227.4 , XM_006510234.1 , NM_001083917.1
Accession Version	NM_001359700.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571846400000
Organism	Mus musculus(house mouse)
Product	sodium channel subunit beta-3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC135353.3 and BC058636.1. On Jan 13, 2018 this sequence version replaced XM_006510234.1. Transcript Variant: This variant (5) differs in the 3' UTR, compared to variant 2. Variants 2, 3 and 5 encode the same protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660825.142654.1, SRR6116558.118374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001346629.1
CDS	413..1060
Translation	MPAFNRLLPLASLVLIYWVRVCFPVCVEVPSETEAVQGNSMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE

Target ORF information:

RefSeq Version	NM_001359700.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001359700.1

ORF Insert Sequence:

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scn3b ( NM_178227.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_839941.1 Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu02846
Clone ID Related Accession (Same CDS sequence)	NM_001359700.1 , NM_178227.4 , XM_006510234.1 , NM_001083917.1
Accession Version	NM_178227.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571414400000
Organism	Mus musculus(house mouse)
Product	sodium channel subunit beta-3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB520894.1, BC053919.1 and AK049747.1. On Apr 11, 2007 this sequence version replaced NM_178227.3. Transcript Variant: This variant (2) represents the longest transcript. Variants 2, 3 and 5 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032253.1, SRR1660811.11040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_839941.1
CDS	413..1060
Translation	MPAFNRLLPLASLVLIYWVRVCFPVCVEVPSETEAVQGNSMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE

Target ORF information:

RefSeq Version	NM_178227.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178227.4

ORF Insert Sequence:

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scn3b ( NM_001083917.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001077386.1 Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu02846
Clone ID Related Accession (Same CDS sequence)	NM_001359700.1 , NM_178227.4 , XM_006510234.1 , NM_001083917.1
Accession Version	NM_001083917.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571414400000
Organism	Mus musculus(house mouse)
Product	sodium channel subunit beta-3 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB520894.1 and BC053919.1. Transcript Variant: This variant (3) differs in the 3' UTR, compared to variant 2. Variants 2, 3 and 5 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058636.1, AK173115.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001077386.1
CDS	413..1060
Translation	MPAFNRLLPLASLVLIYWVRVCFPVCVEVPSETEAVQGNSMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE

Target ORF information:

RefSeq Version	NM_001083917.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001083917.1

ORF Insert Sequence:

ATGCCTGCCT TCAACAGATT GCTTCCCCTA GCTTCTCTAG TGCTCATCTA CTGGGTCAGA 
GTCTGCTTCC CTGTGTGTGT AGAAGTACCC TCGGAGACAG AAGCCGTGCA GGGCAATTCC 
ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Scn3b ( NM_001286614.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001273543.1 Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu17440
Clone ID Related Accession (Same CDS sequence)	NM_001286614.1
Accession Version	NM_001286614.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571587200000
Organism	Mus musculus(house mouse)
Product	sodium channel subunit beta-3 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB520894.1, BC058083.1 and BC058636.1. Transcript Variant: This variant (4) uses an alternate 5' splice site, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 2. It encodes isoform b, which has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849387, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273543.1
CDS	529..1056
Translation	MKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLFIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSVVPVEE

Target ORF information:

RefSeq Version	NM_001286614.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286614.1

ORF Insert Sequence:

ATGAAGCTGA GATGCATCTC CTGCATGAAG AGGGAGGAGG TGGAGGCCAC CACTGTAGTG 
GAGTGGTTCT ACAGGCCTGA GGGCGGTAAA GATTTCCTTA TATATGAGTA TCGAAATGGC 
CACCAGGAGG TGGAGAGCCC CTTCCAAGGT CGTCTGCAGT GGAATGGGAG CAAAGACCTG 
CAGGACGTAT CCATCACTGT TCTCAATGTC ACTCTGAATG ACTCTGGCCT CTACACATGT 
AATGTGTCCA GGGAGTTTGA GTTCGAAGCA CACCGGCCCT TTGTGAAGAC CACAAGACTA 
ATACCCCTGC GAGTCACTGA AGAGGCGGGA GAAGACTTCA CCTCCGTGGT CTCGGAAATC 
ATGATGTACA TCCTCCTGGT CTTCCTCACC TTGTGGCTGT TTATTGAGAT GATCTATTGC 
TACAGAAAGG TCTCTAAGGC CGAAGAGGCA GCTCAGGAAA ATGCGTCTGA CTACCTTGCT 
ATCCCTTCAG AGAACAAGGA GAACTCTGTG GTACCCGTGG AGGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.
Communications biology196(2018)
Ogiwara I,Miyamoto H,Tatsukawa T,Yamagata T,Nakayama T,Atapour N,Miura E,Mazaki E,Ernst SJ,Cao D,Ohtani H,Itohara S,Yanagawa Y,Montal M,Yuzaki M,Inoue Y,Hensch TK,Noebels JL,Yamakawa K

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.
Proceedings of the National Academy of Sciences of the United States of America112(15)E1946-55(2015 Apr)
Bye CR,Jönsson ME,Björklund A,Parish CL,Thompson LH

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.
PLoS genetics10(10)e1004705(2014 Oct)
DiTommaso T,Jones LK,Cottle DL,,Gerdin AK,Vancollie VE,Watt FM,Ramirez-Solis R,Bradley A,Steel KP,Sundberg JP,White JK,Smyth IM

Study of the residues involved in the binding of β1 to β3 subunits in the sodium channel.
Comptes rendus biologies337(2)73-7(2014 Feb)
Liu Q,Jin Y,Wang K,Meng XX,Yang Y,Yang Z,Zhao YS,Zhao MY,Zhang JH

Specification of dopaminergic subsets involves interplay of En1 and Pitx3.
Development (Cambridge, England)140(16)3373-84(2013 Aug)
Veenvliet JV,Dos Santos MT,Kouwenhoven WM,von Oerthel L,Lim JL,van der Linden AJ,Koerkamp MJ,Holstege FC,Smidt MP

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Scn3b cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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