Thbs4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Thbs4
Entrez Gene ID	21828
Full Name	thrombospondin 4
Synonyms	TSP4
General protein information	Preferred Names thrombospondin 4 Names thrombospondin-4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 C3\|13 47.75 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011582.3	NP_035712.1	thrombospondin-4 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	THBS4	XP_003310731.1
Macaca mulatta (Rhesus monkey)	THBS4	XP_001109898.1
Mus musculus (house mouse)	Thbs4	NP_035712.1
Danio rerio (zebrafish)	thbs4b	NP_775333.1
Xenopus tropicalis (tropical clawed frog)	thbs4	NP_001072673.1
Canis lupus familiaris (dog)	THBS4	XP_005618229.1
Rattus norvegicus (Norway rat)	Thbs4	NP_058829.1
Gallus gallus (chicken)	THBS4	XP_424763.4
Homo sapiens (human)	THBS4	NP_003239.2
Bos taurus (cattle)	THBS4	NP_001029900.1

Gene Ontology
Bibliography

Related articles in PubMed

Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension.
Palao T, Medzikovic L, Rippe C, Wanga S, Al-Mardini C, van Weert A, de Vos J, van der Wel NN, van Veen HA, van Bavel ET, Swärd K, de Waard V, Bakker EN
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology3512-19(2018 Jul - Aug)

TBX1 is required for normal stria vascularis and semicircular canal development.
Tian C, Johnson KR
Developmental biology457(1)91-103(2020 Jan)

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart.
Correll RN, Grimes KM, Prasad V, Lynch JM, Khalil H, Molkentin JD
Scientific reports9(1)2059(2019 Feb)

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.
Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD
Nature communications10(1)76(2019 01)

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.
Zoupa M, Xavier GM, Bryan S, Theologidis I, Arno M, Cobourne MT
BMC genomics19(1)429(2018 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Thbs4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thbs4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16303	NM_011582.3 Latest version!	Mus musculus thrombospondin 4 (Thbs4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Thbs4 ( NM_011582.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035712.1 Mus musculus thrombospondin 4 (Thbs4), mRNA.

Price & Availability↑

CloneID	OMu16303
Clone ID Related Accession (Same CDS sequence)	NM_011582.3
Accession Version	NM_011582.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573401600000
Organism	Mus musculus(house mouse)
Product	thrombospondin-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CT025667.9 and CT009509.7. On Dec 15, 2009 this sequence version replaced NM_011582.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF102887.1, BC139414.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849389 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCCC CACGCGCGGC CGCGGCCGCC TTCCTCCTGC TGCACCTGGT CCTGCAGCCG 
TGGCAGCGGA CGAGCGCCCA GGCCACACCC CAGGTCTTTG ATCTTCTACC GTCCTCCAGC 
CAGAGGCTGA ACCCCAGCGC CCTGCAGCCA GTCCTGACAG ATCCCACCCT GCACGAAGTC 
TATCTCATCT CCACCTTCAA GCTGCAGAGT AAAAGCTCAG CCACCATCTT TGGCCTCTAC 
TCCTCAAGTG ACAACAGCAA ATACTTTGAA TTCACTGTGA TGGGACGGCT GAACAAAGCC 
ATCCTCCGCT ACCTGAAGAA TGATGGAAAG ATCCATCTGG TGGTGTTCAA CAACTTGCAG 
CTGGCTGATG GGAGGCGCCA CAGGGTTCTC CTGAGACTGA GCAATTTGCA GAGAGGAGAT 
GGCTCTGTAG AACTCTACCT GGACTGCGCT CAGGCGGACT CGGTGCGCAA CCTCCCCAGA 
GCCTTTTCTG GCCTCACCCA GAACCCAGAG TCCATTGAAT TGCGGACATT CCAGAGGAAG 
CCCCAGGACT TCTTGGAAGA GCTGAAGCTG GTGGTGCGGG GCTCGCTGTT CCAGGTGGCC 
AGCCTCCAAG ACTGCTTCCT GCAGCAGAGT GAGCCTCTGG CTGCCACAAG CACAGGAGAC 
TTTAATCGAC AGTTCTTGGG TCAAATGACA CAACTGAACC AGCTCCTTGG AGAGGTGAAA 
GATCTTCTGA GGCAGCAGGT CAAGGAAACA TCGTTTTTGC GAAACACCAT TGCTGAATGC 
CAAGCTTGTG GTCCTCTCAG CTTTCAGTCC CCAACTCCAA ACACACTGGT GCCCATAGCT 
CCTCCAGCAC CCCCAACTCG CCCAACACGC CACTGTGACT CCAGCCCTTG TTTCCGAGGT 
GTCCGATGTA CGGACACCAG GGATGGCTTC CAGTGTGGAC CCTGCCCAGA TGGTTACACG 
GGAAACGGGA TCACCTGCTC TGACGTGGAT GAGTGCAAAT ACCATCCCTG CTATCCAGGT 
GTGCGCTGTG TGAATTTGGC TCCGGGTTTC AGATGTGACG CCTGTCCAGT AGGTTTCACA 
GGGCCCATGG TGCAGGGTGT CGGGATCAAC TTTGCTAAAA CAAACAAGCA GGTGTGCACT 
GATGTTGATG AGTGTCAGAA TGGAGCGTGT GTTCTGAATT CTATCTGCAT TAACACTTTG 
GGATCTTATC GCTGTGGGCC TTGCAAACCA GGGTACACTG GTGATCAGAC GAGGGGATGC 
AAGACTGAAA GGAGCTGCCG GAACCCAGAG CAGAACCCAT GCAGTGTGCA TGCGCAGTGC 
ATTGAGGAGC GGCAAGGGGA TGTGACGTGT GTGTGTGGTG TTGGCTGGGC TGGTGACGGC 
TATGTCTGTG GAAAGGATGT GGACATTGAC AGTTACCCTG ATGAAGAACT GCCATGCTCT 
GCCAGGAACT GCAAGAAGGA TAACTGCAAG TATGTGCCAA ACTCTGGCCA GGAAGATGCA 
GACAGAGATG GCATCGGAGA CGCGTGTGAT GAGGATGCAG ATGGAGATGG GATCTTGAAT 
GAACAGGACA ACTGTGTCCT GACTCACAAT ATAGACCAAA GGAACAGTGA TAAAGATATC 
TTTGGGGATG CCTGTGACAA CTGCCGGATG GTCCTGAATA ATGACCAGAA GGATACTGAC 
GGGGATGGGA GAGGAGACGC CTGTGATGAC GACATGGATG GAGATGGAAT AAAAAACATT 
TTGGACAACT GTCCCAGAGT TCCCAACCGT GACCAGCAGG ATCGGGATGG TGATGATGTC 
GGAGATGCTT GTGACAGCTG TCCTGATGTC AGTAACCCTA ACCAGTCGGA TGTGGATAAC 
GATCTGGTTG GGGACTCCTG TGACACCAAC CAAGACAGTG ACGGGGATGG CCACCAGGAC 
AGCACAGACA ACTGCCCCAC AGTCATTAAC AGCTCCCAGC TGGACACTGA CAAAGATGGG 
ATCGGCGATG AATGTGATGA CGATGACGAT AACGATGGCA TCCCAGACCT GGTGCCTCCT 
GGCCCAGACA ACTGCAGGCT CGTCCCCAAC CCAGCCCAGG AAGATAGCAA CAATGACGGG 
GTAGGAGATA TCTGTGAAGC TGACTTCGAC CAGGACCAGG TCATCGATCA CATTGATGTG 
TGCCCTGAGA ATGCGGAGAT CACCCTGACT GACTTCAGGG CCTACCAGAC AGTGGTCCTG 
GACCCTGAAG GGGATGCTCA GATCGACCCC AACTGGGTGG TCCTGAACCA GGGCATGGAA 
ATTGTGCAGA CCATGAACAG TGACCCTGGC CTAGCTGTTG GGTACACGGC ATTTAACGGA 
GTTGACTTTG AAGGGACCTT CCACGTAAAC ACCCAGACAG ATGATGACTA TGCTGGCTTT 
ATTTTTGGTT ACCAAGACAG CTCCAGCTTC TATGTAGTCA TGTGGAAGCA AACGGAGCAG 
ACATACTGGC AGGCTACACC GTTCCGTGCA GTAGCAGAAC CTGGTATTCA GCTCAAGGCT 
GTGAAGTCTA AAACTGGCCC AGGGGAACAT CTCCGAAACT CCCTGTGGCA CACAGGGGAC 
ACCAGCGACC AGGTCAGGCT GCTGTGGAAG GACTCCAGGA ATGTGGGCTG GAAGGACAAG 
GTCTCCTACC GCTGGTTCCT GCAGCATAGG CCCCAGGTGG GCTACATCAG GGTGCGCTTT 
TATGAAGGCT CGGAGTTGGT GGCTGACTCT GGGGTCACCA TAGACACCAC CATGCGTGGA 
GGCCGACTTG GTGTGTTCTG CTTCTCTCAA GAAAACATCA TCTGGTCCAA CCTCAAGTAC 
CGCTGCAACG ACACCATACC AGAGGACTTC CAGGAGTTCC AGACCCAGAG TTTCGACCGC 
TTGGATAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035712.1
CDS	146..3037
Translation	MPAPRAAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQPVLTDPTLHEVYLISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGSVELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIAPPAPPTRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTNKQVCTDVDECQNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQSFDRLDN

Target ORF information:

RefSeq Version	NM_011582.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus thrombospondin 4 (Thbs4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011582.3

ORF Insert Sequence:

ATGCCGGCCC CACGCGCGGC CGCGGCCGCC TTCCTCCTGC TGCACCTGGT CCTGCAGCCG 
TGGCAGCGGA CGAGCGCCCA GGCCACACCC CAGGTCTTTG ATCTTCTACC GTCCTCCAGC 
CAGAGGCTGA ACCCCAGCGC CCTGCAGCCA GTCCTGACAG ATCCCACCCT GCACGAAGTC 
TATCTCATCT CCACCTTCAA GCTGCAGAGT AAAAGCTCAG CCACCATCTT TGGCCTCTAC 
TCCTCAAGTG ACAACAGCAA ATACTTTGAA TTCACTGTGA TGGGACGGCT GAACAAAGCC 
ATCCTCCGCT ACCTGAAGAA TGATGGAAAG ATCCATCTGG TGGTGTTCAA CAACTTGCAG 
CTGGCTGATG GGAGGCGCCA CAGGGTTCTC CTGAGACTGA GCAATTTGCA GAGAGGAGAT 
GGCTCTGTAG AACTCTACCT GGACTGCGCT CAGGCGGACT CGGTGCGCAA CCTCCCCAGA 
GCCTTTTCTG GCCTCACCCA GAACCCAGAG TCCATTGAAT TGCGGACATT CCAGAGGAAG 
CCCCAGGACT TCTTGGAAGA GCTGAAGCTG GTGGTGCGGG GCTCGCTGTT CCAGGTGGCC 
AGCCTCCAAG ACTGCTTCCT GCAGCAGAGT GAGCCTCTGG CTGCCACAAG CACAGGAGAC 
TTTAATCGAC AGTTCTTGGG TCAAATGACA CAACTGAACC AGCTCCTTGG AGAGGTGAAA 
GATCTTCTGA GGCAGCAGGT CAAGGAAACA TCGTTTTTGC GAAACACCAT TGCTGAATGC 
CAAGCTTGTG GTCCTCTCAG CTTTCAGTCC CCAACTCCAA ACACACTGGT GCCCATAGCT 
CCTCCAGCAC CCCCAACTCG CCCAACACGC CACTGTGACT CCAGCCCTTG TTTCCGAGGT 
GTCCGATGTA CGGACACCAG GGATGGCTTC CAGTGTGGAC CCTGCCCAGA TGGTTACACG 
GGAAACGGGA TCACCTGCTC TGACGTGGAT GAGTGCAAAT ACCATCCCTG CTATCCAGGT 
GTGCGCTGTG TGAATTTGGC TCCGGGTTTC AGATGTGACG CCTGTCCAGT AGGTTTCACA 
GGGCCCATGG TGCAGGGTGT CGGGATCAAC TTTGCTAAAA CAAACAAGCA GGTGTGCACT 
GATGTTGATG AGTGTCAGAA TGGAGCGTGT GTTCTGAATT CTATCTGCAT TAACACTTTG 
GGATCTTATC GCTGTGGGCC TTGCAAACCA GGGTACACTG GTGATCAGAC GAGGGGATGC 
AAGACTGAAA GGAGCTGCCG GAACCCAGAG CAGAACCCAT GCAGTGTGCA TGCGCAGTGC 
ATTGAGGAGC GGCAAGGGGA TGTGACGTGT GTGTGTGGTG TTGGCTGGGC TGGTGACGGC 
TATGTCTGTG GAAAGGATGT GGACATTGAC AGTTACCCTG ATGAAGAACT GCCATGCTCT 
GCCAGGAACT GCAAGAAGGA TAACTGCAAG TATGTGCCAA ACTCTGGCCA GGAAGATGCA 
GACAGAGATG GCATCGGAGA CGCGTGTGAT GAGGATGCAG ATGGAGATGG GATCTTGAAT 
GAACAGGACA ACTGTGTCCT GACTCACAAT ATAGACCAAA GGAACAGTGA TAAAGATATC 
TTTGGGGATG CCTGTGACAA CTGCCGGATG GTCCTGAATA ATGACCAGAA GGATACTGAC 
GGGGATGGGA GAGGAGACGC CTGTGATGAC GACATGGATG GAGATGGAAT AAAAAACATT 
TTGGACAACT GTCCCAGAGT TCCCAACCGT GACCAGCAGG ATCGGGATGG TGATGATGTC 
GGAGATGCTT GTGACAGCTG TCCTGATGTC AGTAACCCTA ACCAGTCGGA TGTGGATAAC 
GATCTGGTTG GGGACTCCTG TGACACCAAC CAAGACAGTG ACGGGGATGG CCACCAGGAC 
AGCACAGACA ACTGCCCCAC AGTCATTAAC AGCTCCCAGC TGGACACTGA CAAAGATGGG 
ATCGGCGATG AATGTGATGA CGATGACGAT AACGATGGCA TCCCAGACCT GGTGCCTCCT 
GGCCCAGACA ACTGCAGGCT CGTCCCCAAC CCAGCCCAGG AAGATAGCAA CAATGACGGG 
GTAGGAGATA TCTGTGAAGC TGACTTCGAC CAGGACCAGG TCATCGATCA CATTGATGTG 
TGCCCTGAGA ATGCGGAGAT CACCCTGACT GACTTCAGGG CCTACCAGAC AGTGGTCCTG 
GACCCTGAAG GGGATGCTCA GATCGACCCC AACTGGGTGG TCCTGAACCA GGGCATGGAA 
ATTGTGCAGA CCATGAACAG TGACCCTGGC CTAGCTGTTG GGTACACGGC ATTTAACGGA 
GTTGACTTTG AAGGGACCTT CCACGTAAAC ACCCAGACAG ATGATGACTA TGCTGGCTTT 
ATTTTTGGTT ACCAAGACAG CTCCAGCTTC TATGTAGTCA TGTGGAAGCA AACGGAGCAG 
ACATACTGGC AGGCTACACC GTTCCGTGCA GTAGCAGAAC CTGGTATTCA GCTCAAGGCT 
GTGAAGTCTA AAACTGGCCC AGGGGAACAT CTCCGAAACT CCCTGTGGCA CACAGGGGAC 
ACCAGCGACC AGGTCAGGCT GCTGTGGAAG GACTCCAGGA ATGTGGGCTG GAAGGACAAG 
GTCTCCTACC GCTGGTTCCT GCAGCATAGG CCCCAGGTGG GCTACATCAG GGTGCGCTTT 
TATGAAGGCT CGGAGTTGGT GGCTGACTCT GGGGTCACCA TAGACACCAC CATGCGTGGA 
GGCCGACTTG GTGTGTTCTG CTTCTCTCAA GAAAACATCA TCTGGTCCAA CCTCAAGTAC 
CGCTGCAACG ACACCATACC AGAGGACTTC CAGGAGTTCC AGACCCAGAG TTTCGACCGC 
TTGGATAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology3512-19(2018 Jul - Aug)
Palao T,Medzikovic L,Rippe C,Wanga S,Al-Mardini C,van Weert A,de Vos J,van der Wel NN,van Veen HA,van Bavel ET,Swärd K,de Waard V,Bakker EN

TBX1 is required for normal stria vascularis and semicircular canal development.
Developmental biology457(1)91-103(2020 Jan)
Tian C,Johnson KR

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart.
Scientific reports9(1)2059(2019 Feb)
Correll RN,Grimes KM,Prasad V,Lynch JM,Khalil H,Molkentin JD

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.
Nature communications10(1)76(2019 01)
Schips TG,Vanhoutte D,Vo A,Correll RN,Brody MJ,Khalil H,Karch J,Tjondrokoesoemo A,Sargent MA,Maillet M,Ross RS,Molkentin JD

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.
BMC genomics19(1)429(2018 Jun)
Zoupa M,Xavier GM,Bryan S,Theologidis I,Arno M,Cobourne MT

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Thbs4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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