Nup153 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nup153
Entrez Gene ID	218210
Full Name	nucleoporin 153
Synonyms	B130015D15Rik,C88147
General protein information	Preferred Names nucleoporin 153 Names nuclear pore complex protein Nup153
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A5

mRNA and Protein(s)

mRNA	Protein	Name
NM_175749.2	NP_786925.2	nuclear pore complex protein Nup153

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Nup153	NP_786925.2
Gallus gallus (chicken)	NUP153	XP_418937.4
Xenopus tropicalis (tropical clawed frog)	nup153	XP_002932736.2
Canis lupus familiaris (dog)	NUP153	XP_535898.2
Rattus norvegicus (Norway rat)	Nup153	NP_001093940.1
Homo sapiens (human)	NUP153	NP_001265139.1
Bos taurus (cattle)	NUP153	NP_001192683.1
Pan troglodytes (chimpanzee)	NUP153	XP_001170682.1
Macaca mulatta (Rhesus monkey)	NUP153	XP_001096101.1
Danio rerio (zebrafish)	nup153	XP_700317.6

Gene Ontology
Bibliography

Related articles in PubMed

Altered Nup153 Expression Impairs the Function of Cultured Hippocampal Neural Stem Cells Isolated from a Mouse Model of Alzheimer's Disease.
Leone L, Colussi C, Gironi K, Longo V, Fusco S, Li Puma DD, D'Ascenzo M, Grassi C
Molecular neurobiology56(8)5934-5949(2019 Aug)

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells.
Sachani SS, Landschoot LS, Zhang L, White CR, MacDonald WA, Golding MC, Mann MRW
Nature communications9(1)2795(2018 07)

Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.
Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer MW, Gage FH
Cell stem cell21(5)618-634.e7(2017 Nov)

Lamin B1 protein is required for dendrite development in primary mouse cortical neurons.
Giacomini C, Mahajani S, Ruffilli R, Marotta R, Gasparini L
Molecular biology of the cell27(1)35-47(2016 Jan)

The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing.
Jacinto FV, Benner C, Hetzer MW
Genes & development29(12)1224-38(2015 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nup153 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nup153 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06194	NM_175749.2 Latest version!	Mus musculus nucleoporin 153 (Nup153), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nup153 ( NM_175749.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_786925.2 Mus musculus nucleoporin 153 (Nup153), mRNA.

Price & Availability↑

CloneID	OMu06194
Clone ID Related Accession (Same CDS sequence)	NM_175749.2
Accession Version	NM_175749.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	nuclear pore complex protein Nup153
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK086847.1, CF898039.1, CA326562.1, CK638380.1, CF897724.1, AK044947.1, BM950067.1 and AK031006.1. On Jul 23, 2009 this sequence version replaced NM_175749.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCGG AAGCCGGAGG CATAGGAGGG GGCGGCGGCG GCGGCAAGAT CCGGACTCGT 
CGTTGCCACC AGGGGCCGGT GAAGCCTTAC CAACAGGGGC GACCCCAACA CCAGGGCATT 
CTTAGCAGGG TTACAGAATC TGTTAAGAAT ATTGTACCAG GGTGGCTACA AAGATACTTC 
AACAAGAGTG AAAATGCTTG CAGCTGTTCA CCAGATGCAG ATGAAGTTCC ACCCTGGCCA 
GAAAATAGAG AAGATGAGCA TGCGATTTAT GCGGATGAGA ACACAAACAC TGATGATGGG 
AGAATCACCC CTGACCCTGC AGGCAGTAAC ACAGAAGAAC CATCAACAAC CAGTACTGCT 
TCAAATTATC CAGATGTGTT AACAAGACCT TCTCTTCATC GGAGTCATCT GAATTTCTCT 
GTGTTGGAAT CCCCTGCTTT GCACTGTCAG CCGTCCACAT CCTCTGCGTT CCCAATCGGC 
AGTTCTGGAT TTTCCCTTGT GAAGGAGATT AAAGATTCTA CCTCTCAGCA TGATGATGAT 
AACATCTCAA CTACCAGTGG GTTCTCTTCA AGAGCTTCTG AGAAAGATAT AGCTGTTTCA 
AAGAACACTT CCCTGCCACC TTTGTGGTCC CCTGAAGCAG AACGTTCTCA TTCACTCTCA 
CAGCATACTG CCATCAGCTC CAAAAAACCA GCATTCAACT TGTCTGCCTT TGGAACACTT 
TCCACCTCAC TTGGGAATTC TTCAATTCTT AAAACAAGTC AGCTTGGAGA CTCTCCTTTT 
TATCCTGGCA AAACAACATA TGGAGGGGCA GCTGCTGCTG TAAGACAGAA TAAAGTACGA 
AGTACACCTT ACCAGGCTCC AGTTAGAAGA CAGATGAAAG CTAAGCAGCT CAATGCACAG 
TCTTATGGTG TGACCAGCTC AACAGCACGG CGGATACTGC AGTCATTAGA AAAGATGTCG 
AGCCCTCTTG CGGATGCAAA AAGAATTCCA TCTGCAGTTT CTTCTCCTCT GAATTCTCCT 
CTTGATAGGA GTGGGATAGA TAACACAGTT TTTCAGGCAA AAAAAGAAAA GGTGGACTCT 
CAGTATCCCC CTGTTCAGAG ACTAATGACC CCAAAGCCAG TTTCCATAGC AACAAATAGA 
ACTGTCTATT TTAAACCATC TCTGACCCCA TCTGGTGACT TAAGGAAGAC TAATCAAAGG 
ATAGATAAAA AGAACAGTAC TGTAGATGAA AAAAGTATCT CAAGACAAAA TAGAGAGCAA 
GAAAGTGGCT TTTCATACCC CAATTTCAGT ATTCCTGCAG CCAATGGTTT ATCTTCTGGA 
GTAGGTGGTG GAGGTGGCAA GATGAGAAGA GAGAGAACAC ATTTTGTTGC TCCTAAACCT 
CCAGAGAATG AGGAAGTGGA AGCACCATTG TTACCGCAAA TCTCTCTACC AATCAGCAGT 
TCTTCACTGC CCACCTTCAG TTTTAGTTCC CCTGTGACCT CGGCTTCTCC TTCACCAGTC 
AGCTCTTCTC AGCCATTACC AAACAAGGTA CAGATGACCT CTCTGGGCAG CACGGGCAGT 
CCTGTGTTCA CATTCTCATC TCCCATTGTA AAATCCACGC AGGCAGCTGT GCTCCCTCCA 
GCATCTATTG GATTTACATT TAGTGTGCCT CTTGCAAAAA CTGAATTTTC TGGCTCTAAT 
AGTTCTTCAG AAACAGTTTT AAGTAGTTCA GCCCAAGATA TCACTGCAGT GAATAGTTCA 
AGCTATAAGA AGCGAAGTGC TCCTTGTGAG GACCCCTTTA CACCTGCAAA GATCCTGAGA 
GAAGGAAGTG TTCTAGACAT TCTGAAAACA CCTGGTTTCG CATCACCAAA GGTTGATTCT 
CCTGCTCTTC AACCCACTAC CACAAGCTCA ATAGTTTATA CAAGACCAGC AATAAGTACT 
TTTTCTTCTA GTGGAATTGA GTATGGAGAA AGTTTAAAAG CTGGATCATC ATGGCAGTGT 
GACACATGTC TCCTCCAGAA CAAAGTCACA GACAATAAGT GTATAGCCTG CCAAGCAGCA 
AAACTGCCCC TGAAAGAAAC TGCTAAACAG ACTGGGACTG GGACACCAAG CAAAAGTGAC 
AAACCAGCCT CTACATCAGG GACAGGCTTT GGAGATAAAT TTAAACCAGC AATAGGAACT 
TGGGATTGTG ATACCTGTTT AGTGCAAAAT AAGCCCGAAG CAGTAAAATG TGTAGCCTGT 
GAGACACCTA AGCCTGGCAC TGGTGTGAAG CGAGCCCTTA CATTGACAGT GGCTTCAGAA 
AGTCCTGTGA CTGCTTCCTC TTCTACCACT GTGACAACTG GTACACTAGG ATTTGGAGAT 
AAATTCAAAA GGCCTGTGGG CTCTTGGGAG TGTCCAGTCT GCTGTGTTTG TAATAAGGCA 
GAAGACAACA GATGTGTTTC CTGTACATCT GAGAAACCAG GTTTGGTATC TGCCTCAAGC 
AGCAGCCCTG CCCCTGTCTC TCTGTCTTCT GGAGGCTGTT TAGGATTGGA CAAGTTTAAA 
AAGCCCGAGG GAAGCTGGGA CTGTGAAGTG TGCCTAGTGC AAAATAAAGC AGACTCTGCC 
AAGTGCATAG CTTGTGAAAG TGCAAAGCCA GGCACAAAGT CTGAGTTTAA AGGCTTCGGG 
ACATCTTCAT CTTTAAATCC AGCACCCTCA GCCTTCAAAT TTGGTATTCC ATCGTCCTCT 
TCTGGGCTTT CTCAAACTTT GACAAGCACT GGAAATTTTA AATTTGGAGA TCAGGGAGGA 
TTCAAATTAG GCACTTCATC TGACTCTGGG TCTACAAACA CCATGAATAC AAACTTTAAA 
TTTTCTAAAC CAACTGGAGA CTTTAAATTT GGAGTGTTAT CTGATTCTAA ACCTGAAGAA 
GTTAAAAACG ACAACAAGAA TGATAATTTT CAGTTTGGAT CTTCTTCTGG CTTAACCAAC 
CCAGCTTCTT CAGCTCCGTT TCAGTTTGGG GTATCTACTC TTGGGCAACA AGAAAAGAAA 
GAGGAGCTGC CTAAATCTTC ACCTGCAGGC TTTAGCTTTG GTGCAGGTGT TAATAACCCC 
CCTAATGCTG CTATTGACAC CACAGCGACC TCAGAGAACA AGAGCGGCTT CAACTTTGGA 
ACCCTAGACA CAAAGAGTGT CTCAGTGACT CCTTTCACAT ACAAGACAAC AGAAGCAAAG 
AAAGAAGACG CACCTGCTAC CAAGGGTGGG TTCACATTTG GTAAAGTGGG CTCCTCTTCT 
TTGCCATCTT CCTCAATGTT TGTTTTGGGA AGGACAGAGG AGAAACAGCA AGAACCTGTT 
ACTTCTACTT CTCTGGTGTT TGGGAAGAAA GCCGACAGTG AGGAGCCAAA GTGTCAGCCA 
GTATTTTCCT TTGGGAATTC AGAGCAAACC AAAGATGAGA GCTCCAAGCC GACATTCAGC 
TTCAGTGTGG CAAAACCATC TGGGAAGGAG TCTGAGCAGC TAGCCAAGGC TACTTTTGCA 
TTTGGAAATC AAACCAATAC AACAACTGAT CAAGGTGCAG CAAAGCCAGT TTTTAGCTTC 
TTGAACAGCA GTTCCTCTAG TTCAAGTGCA CCAGCCACTT CATCTAGTGG TGGCATATTT 
GGTAGTTCCA CCTCTTCCTC CAACCCACCT GTGGCAGCCT TTGTGTTTGG ACAGGCCAGC 
AATCCTGTCA GCAGCTCTGC CTTCGGTAAC GCTGCTGAAT CCAGTACATC TCAGTCTTTG 
CTATTTCCTC AAGAGAGCGA GCCAGCCACC ACGTCCAGCA CTGCCCCAGC TGCCTCTCCC 
TTTGTATTTG GGACAGGAGC CAGCAGTAAT AGTGTGTCTT CTGGGTTCAC TTTTGGGGCT 
ACAACCACGT CAAGCTCTTC AGGATCCTCC TTTGTATTTG GCACTGGACA TTCAGCACCA 
TCTGCCAGTC CAGCATTTGG TGCTAACCAG ACTCCAACAT TTGGACAAAG TCAAGGTGCC 
AGCCAGCCTA ACCCGCCAAG CTTTGGCTCT ATCTCGTCTT CAACAGCATT ATTTTCTGCT 
GGTTCTCAGC CTGTACCACC ACCTATATTT GGGACAGTGT CAAGCAGCAG CCAACCTCCT 
GTGTTTGGAC AGCAGCCTAG TCAGTCTGCA TTTGGCTCTG GGACAGCTAA TGCCAGTTCG 
GTTTTCCAAT TTGGTAGCAG CACTACGAAT TTCAACTTCA CAAACAATAA TCCATCAGGA 
GTGTTCACAT TTGGTGCAAG TCCCAGCACG CCTGCAGCCT CAGCCCAGCC CTCAGGTTCA 
GGGGTCTTTT CATTCAGCCA GTCTCCAGCA TCATTTACAG TGGGGTCAAA TGGGAAAAAT 
ATGTTCTCTT CTTCCGGAAC TTCAGTTTCT GGTCGCAAGA TAAAGACTGC TGTTAGACGC 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_786925.2
CDS	377..4765
Translation	MASEAGGIGGGGGGGKIRTRRCHQGPVKPYQQGRPQHQGILSRVTESVKNIVPGWLQRYFNKSENACSCSPDADEVPPWPENREDEHAIYADENTNTDDGRITPDPAGSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSVLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASEKDIAVSKNTSLPPLWSPEAERSHSLSQHTAISSKKPAFNLSAFGTLSTSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQNKVRSTPYQAPVRRQMKAKQLNAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSAVSSPLNSPLDRSGIDNTVFQAKKEKVDSQYPPVQRLMTPKPVSIATNRTVYFKPSLTPSGDLRKTNQRIDKKNSTVDEKSISRQNREQESGFSYPNFSIPAANGLSSGVGGGGGKMRRERTHFVAPKPPENEEVEAPLLPQISLPISSSSLPTFSFSSPVTSASPSPVSSSQPLPNKVQMTSLGSTGSPVFTFSSPIVKSTQAAVLPPASIGFTFSVPLAKTEFSGSNSSSETVLSSSAQDITAVNSSSYKKRSAPCEDPFTPAKILREGSVLDILKTPGFASPKVDSPALQPTTTSSIVYTRPAISTFSSSGIEYGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLPLKETAKQTGTGTPSKSDKPASTSGTGFGDKFKPAIGTWDCDTCLVQNKPEAVKCVACETPKPGTGVKRALTLTVASESPVTASSSTTVTTGTLGFGDKFKRPVGSWECPVCCVCNKAEDNRCVSCTSEKPGLVSASSSSPAPVSLSSGGCLGLDKFKKPEGSWDCEVCLVQNKADSAKCIACESAKPGTKSEFKGFGTSSSLNPAPSAFKFGIPSSSSGLSQTLTSTGNFKFGDQGGFKLGTSSDSGSTNTMNTNFKFSKPTGDFKFGVLSDSKPEEVKNDNKNDNFQFGSSSGLTNPASSAPFQFGVSTLGQQEKKEELPKSSPAGFSFGAGVNNPPNAAIDTTATSENKSGFNFGTLDTKSVSVTPFTYKTTEAKKEDAPATKGGFTFGKVGSSSLPSSSMFVLGRTEEKQQEPVTSTSLVFGKKADSEEPKCQPVFSFGNSEQTKDESSKPTFSFSVAKPSGKESEQLAKATFAFGNQTNTTTDQGAAKPVFSFLNSSSSSSSAPATSSSGGIFGSSTSSSNPPVAAFVFGQASNPVSSSAFGNAAESSTSQSLLFPQESEPATTSSTAPAASPFVFGTGASSNSVSSGFTFGATTTSSSSGSSFVFGTGHSAPSASPAFGANQTPTFGQSQGASQPNPPSFGSISSSTALFSAGSQPVPPPIFGTVSSSSQPPVFGQQPSQSAFGSGTANASSVFQFGSSTTNFNFTNNNPSGVFTFGASPSTPAASAQPSGSGVFSFSQSPASFTVGSNGKNMFSSSGTSVSGRKIKTAVRRKK

Target ORF information:

RefSeq Version	NM_175749.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus nucleoporin 153 (Nup153), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175749.2

ORF Insert Sequence:

ATGGCCTCGG AAGCCGGAGG CATAGGAGGG GGCGGCGGCG GCGGCAAGAT CCGGACTCGT 
CGTTGCCACC AGGGGCCGGT GAAGCCTTAC CAACAGGGGC GACCCCAACA CCAGGGCATT 
CTTAGCAGGG TTACAGAATC TGTTAAGAAT ATTGTACCAG GGTGGCTACA AAGATACTTC 
AACAAGAGTG AAAATGCTTG CAGCTGTTCA CCAGATGCAG ATGAAGTTCC ACCCTGGCCA 
GAAAATAGAG AAGATGAGCA TGCGATTTAT GCGGATGAGA ACACAAACAC TGATGATGGG 
AGAATCACCC CTGACCCTGC AGGCAGTAAC ACAGAAGAAC CATCAACAAC CAGTACTGCT 
TCAAATTATC CAGATGTGTT AACAAGACCT TCTCTTCATC GGAGTCATCT GAATTTCTCT 
GTGTTGGAAT CCCCTGCTTT GCACTGTCAG CCGTCCACAT CCTCTGCGTT CCCAATCGGC 
AGTTCTGGAT TTTCCCTTGT GAAGGAGATT AAAGATTCTA CCTCTCAGCA TGATGATGAT 
AACATCTCAA CTACCAGTGG GTTCTCTTCA AGAGCTTCTG AGAAAGATAT AGCTGTTTCA 
AAGAACACTT CCCTGCCACC TTTGTGGTCC CCTGAAGCAG AACGTTCTCA TTCACTCTCA 
CAGCATACTG CCATCAGCTC CAAAAAACCA GCATTCAACT TGTCTGCCTT TGGAACACTT 
TCCACCTCAC TTGGGAATTC TTCAATTCTT AAAACAAGTC AGCTTGGAGA CTCTCCTTTT 
TATCCTGGCA AAACAACATA TGGAGGGGCA GCTGCTGCTG TAAGACAGAA TAAAGTACGA 
AGTACACCTT ACCAGGCTCC AGTTAGAAGA CAGATGAAAG CTAAGCAGCT CAATGCACAG 
TCTTATGGTG TGACCAGCTC AACAGCACGG CGGATACTGC AGTCATTAGA AAAGATGTCG 
AGCCCTCTTG CGGATGCAAA AAGAATTCCA TCTGCAGTTT CTTCTCCTCT GAATTCTCCT 
CTTGATAGGA GTGGGATAGA TAACACAGTT TTTCAGGCAA AAAAAGAAAA GGTGGACTCT 
CAGTATCCCC CTGTTCAGAG ACTAATGACC CCAAAGCCAG TTTCCATAGC AACAAATAGA 
ACTGTCTATT TTAAACCATC TCTGACCCCA TCTGGTGACT TAAGGAAGAC TAATCAAAGG 
ATAGATAAAA AGAACAGTAC TGTAGATGAA AAAAGTATCT CAAGACAAAA TAGAGAGCAA 
GAAAGTGGCT TTTCATACCC CAATTTCAGT ATTCCTGCAG CCAATGGTTT ATCTTCTGGA 
GTAGGTGGTG GAGGTGGCAA GATGAGAAGA GAGAGAACAC ATTTTGTTGC TCCTAAACCT 
CCAGAGAATG AGGAAGTGGA AGCACCATTG TTACCGCAAA TCTCTCTACC AATCAGCAGT 
TCTTCACTGC CCACCTTCAG TTTTAGTTCC CCTGTGACCT CGGCTTCTCC TTCACCAGTC 
AGCTCTTCTC AGCCATTACC AAACAAGGTA CAGATGACCT CTCTGGGCAG CACGGGCAGT 
CCTGTGTTCA CATTCTCATC TCCCATTGTA AAATCCACGC AGGCAGCTGT GCTCCCTCCA 
GCATCTATTG GATTTACATT TAGTGTGCCT CTTGCAAAAA CTGAATTTTC TGGCTCTAAT 
AGTTCTTCAG AAACAGTTTT AAGTAGTTCA GCCCAAGATA TCACTGCAGT GAATAGTTCA 
AGCTATAAGA AGCGAAGTGC TCCTTGTGAG GACCCCTTTA CACCTGCAAA GATCCTGAGA 
GAAGGAAGTG TTCTAGACAT TCTGAAAACA CCTGGTTTCG CATCACCAAA GGTTGATTCT 
CCTGCTCTTC AACCCACTAC CACAAGCTCA ATAGTTTATA CAAGACCAGC AATAAGTACT 
TTTTCTTCTA GTGGAATTGA GTATGGAGAA AGTTTAAAAG CTGGATCATC ATGGCAGTGT 
GACACATGTC TCCTCCAGAA CAAAGTCACA GACAATAAGT GTATAGCCTG CCAAGCAGCA 
AAACTGCCCC TGAAAGAAAC TGCTAAACAG ACTGGGACTG GGACACCAAG CAAAAGTGAC 
AAACCAGCCT CTACATCAGG GACAGGCTTT GGAGATAAAT TTAAACCAGC AATAGGAACT 
TGGGATTGTG ATACCTGTTT AGTGCAAAAT AAGCCCGAAG CAGTAAAATG TGTAGCCTGT 
GAGACACCTA AGCCTGGCAC TGGTGTGAAG CGAGCCCTTA CATTGACAGT GGCTTCAGAA 
AGTCCTGTGA CTGCTTCCTC TTCTACCACT GTGACAACTG GTACACTAGG ATTTGGAGAT 
AAATTCAAAA GGCCTGTGGG CTCTTGGGAG TGTCCAGTCT GCTGTGTTTG TAATAAGGCA 
GAAGACAACA GATGTGTTTC CTGTACATCT GAGAAACCAG GTTTGGTATC TGCCTCAAGC 
AGCAGCCCTG CCCCTGTCTC TCTGTCTTCT GGAGGCTGTT TAGGATTGGA CAAGTTTAAA 
AAGCCCGAGG GAAGCTGGGA CTGTGAAGTG TGCCTAGTGC AAAATAAAGC AGACTCTGCC 
AAGTGCATAG CTTGTGAAAG TGCAAAGCCA GGCACAAAGT CTGAGTTTAA AGGCTTCGGG 
ACATCTTCAT CTTTAAATCC AGCACCCTCA GCCTTCAAAT TTGGTATTCC ATCGTCCTCT 
TCTGGGCTTT CTCAAACTTT GACAAGCACT GGAAATTTTA AATTTGGAGA TCAGGGAGGA 
TTCAAATTAG GCACTTCATC TGACTCTGGG TCTACAAACA CCATGAATAC AAACTTTAAA 
TTTTCTAAAC CAACTGGAGA CTTTAAATTT GGAGTGTTAT CTGATTCTAA ACCTGAAGAA 
GTTAAAAACG ACAACAAGAA TGATAATTTT CAGTTTGGAT CTTCTTCTGG CTTAACCAAC 
CCAGCTTCTT CAGCTCCGTT TCAGTTTGGG GTATCTACTC TTGGGCAACA AGAAAAGAAA 
GAGGAGCTGC CTAAATCTTC ACCTGCAGGC TTTAGCTTTG GTGCAGGTGT TAATAACCCC 
CCTAATGCTG CTATTGACAC CACAGCGACC TCAGAGAACA AGAGCGGCTT CAACTTTGGA 
ACCCTAGACA CAAAGAGTGT CTCAGTGACT CCTTTCACAT ACAAGACAAC AGAAGCAAAG 
AAAGAAGACG CACCTGCTAC CAAGGGTGGG TTCACATTTG GTAAAGTGGG CTCCTCTTCT 
TTGCCATCTT CCTCAATGTT TGTTTTGGGA AGGACAGAGG AGAAACAGCA AGAACCTGTT 
ACTTCTACTT CTCTGGTGTT TGGGAAGAAA GCCGACAGTG AGGAGCCAAA GTGTCAGCCA 
GTATTTTCCT TTGGGAATTC AGAGCAAACC AAAGATGAGA GCTCCAAGCC GACATTCAGC 
TTCAGTGTGG CAAAACCATC TGGGAAGGAG TCTGAGCAGC TAGCCAAGGC TACTTTTGCA 
TTTGGAAATC AAACCAATAC AACAACTGAT CAAGGTGCAG CAAAGCCAGT TTTTAGCTTC 
TTGAACAGCA GTTCCTCTAG TTCAAGTGCA CCAGCCACTT CATCTAGTGG TGGCATATTT 
GGTAGTTCCA CCTCTTCCTC CAACCCACCT GTGGCAGCCT TTGTGTTTGG ACAGGCCAGC 
AATCCTGTCA GCAGCTCTGC CTTCGGTAAC GCTGCTGAAT CCAGTACATC TCAGTCTTTG 
CTATTTCCTC AAGAGAGCGA GCCAGCCACC ACGTCCAGCA CTGCCCCAGC TGCCTCTCCC 
TTTGTATTTG GGACAGGAGC CAGCAGTAAT AGTGTGTCTT CTGGGTTCAC TTTTGGGGCT 
ACAACCACGT CAAGCTCTTC AGGATCCTCC TTTGTATTTG GCACTGGACA TTCAGCACCA 
TCTGCCAGTC CAGCATTTGG TGCTAACCAG ACTCCAACAT TTGGACAAAG TCAAGGTGCC 
AGCCAGCCTA ACCCGCCAAG CTTTGGCTCT ATCTCGTCTT CAACAGCATT ATTTTCTGCT 
GGTTCTCAGC CTGTACCACC ACCTATATTT GGGACAGTGT CAAGCAGCAG CCAACCTCCT 
GTGTTTGGAC AGCAGCCTAG TCAGTCTGCA TTTGGCTCTG GGACAGCTAA TGCCAGTTCG 
GTTTTCCAAT TTGGTAGCAG CACTACGAAT TTCAACTTCA CAAACAATAA TCCATCAGGA 
GTGTTCACAT TTGGTGCAAG TCCCAGCACG CCTGCAGCCT CAGCCCAGCC CTCAGGTTCA 
GGGGTCTTTT CATTCAGCCA GTCTCCAGCA TCATTTACAG TGGGGTCAAA TGGGAAAAAT 
ATGTTCTCTT CTTCCGGAAC TTCAGTTTCT GGTCGCAAGA TAAAGACTGC TGTTAGACGC 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered Nup153 Expression Impairs the Function of Cultured Hippocampal Neural Stem Cells Isolated from a Mouse Model of Alzheimer's Disease.
Molecular neurobiology56(8)5934-5949(2019 Aug)
Leone L,Colussi C,Gironi K,Longo V,Fusco S,Li Puma DD,D'Ascenzo M,Grassi C

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells.
Nature communications9(1)2795(2018 07)
Sachani SS,Landschoot LS,Zhang L,White CR,MacDonald WA,Golding MC,Mann MRW

Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.
Cell stem cell21(5)618-634.e7(2017 Nov)
Toda T,Hsu JY,Linker SB,Hu L,Schafer ST,Mertens J,Jacinto FV,Hetzer MW,Gage FH

Lamin B1 protein is required for dendrite development in primary mouse cortical neurons.
Molecular biology of the cell27(1)35-47(2016 Jan)
Giacomini C,Mahajani S,Ruffilli R,Marotta R,Gasparini L

The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing.
Genes & development29(12)1224-38(2015 Jun)
Jacinto FV,Benner C,Hetzer MW

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Nup153 cDNA ORF clone, Mus musculus(house mouse)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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