Inmt cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Inmt
Entrez Gene ID	21743
Full Name	indolethylamine N-methyltransferase
Synonyms	Temt
General protein information	Preferred Names indolethylamine N-methyltransferase Names indolethylamine N-methyltransferase amine N-methyltransferase aromatic alkylamine N-methyltransferase arylamine N-methyltransferase indolamine N-methyltransferase nicotine N-methyltransferase thioether S-methyltransferase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_009349.3	NP_033375.1	indolethylamine N-methyltransferase

Pathways from BioSystems

Homologies

Homo sapiens (human)	INMT	NP_006765.4
Macaca mulatta (Rhesus monkey)	INMT	XP_001084895.1
Rattus norvegicus (Norway rat)	Inmt	NP_001102492.1
Pan troglodytes (chimpanzee)	INMT	XP_527713.3
Bos taurus (cattle)	INMT	NP_001179577.1
Danio rerio (zebrafish)	zgc:64002	NP_001104716.2
Danio rerio (zebrafish)	LOC100538230	XP_003199510.1
Mus musculus (house mouse)	Inmt	NP_033375.1
Xenopus tropicalis (tropical clawed frog)	MGC107884	NP_001015730.1

Gene Ontology
Bibliography

Related articles in PubMed

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.
Zieman AG, Poll BG, Ma J, Coulombe PA
Human molecular genetics28(13)2255-2270(2019 07)

Bmp4 from the optic vesicle specifies murine retina formation.
Huang J, Liu Y, Oltean A, Beebe DC
Developmental biology402(1)119-26(2015 Jun)

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Alpern D, Langer D, Ballester B, Le Gras S, Romier C, Mengus G, Davidson I
eLife3e03613(2014 Sep)

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.
Im SK, Jeong H, Jeong HW, Kim KT, Hwang D, Ikegami M, Kong YY
PloS one8(3)e58511(2013)

Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N,N'-dimethyltryptamine forming enzyme, indole-N-methyl transferase.
Mavlyutov TA, Epstein ML, Liu P, Verbny YI, Ziskind-Conhaim L, Ruoho AE
Neuroscience20660-8(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Inmt gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Inmt cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16249	NM_009349.3 Latest version!	Mus musculus indolethylamine N-methyltransferase (Inmt), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Inmt ( NM_009349.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033375.1 Mus musculus indolethylamine N-methyltransferase (Inmt), mRNA.

Price & Availability↑

CloneID	OMu16249
Clone ID Related Accession (Same CDS sequence)	NM_009349.3
Accession Version	NM_009349.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	indolethylamine N-methyltransferase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC079243.7. On Apr 27, 2007 this sequence version replaced NM_009349.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK002281.1, AK013010.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849386 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGCA AGGTATACAT AGGAGGTGAG GACTATGAAA AAGAGTTCAC TCCCAAAGAC 
TACCTGACCA CCTACTACAG CTTCCACTCT GGCCCTGTGG CAGAGCAGGA AATCGTAAAG 
TTTAGCCTGC AGAACCTCTA CCAGACCTTC TCTACAGGAG GTGTAGGGGG CGACGTCCTG 
ATCGACATTG GCTCTGGCCC TACCATCTAC CAGCTGCTTT CAGCATGCGA GGTCTTCCGG 
GAGATCATTG TCACTGACTA CACCCCGCAG AACCTGCAGG AGCTGCAGAA GTGGCTGAAG 
AAAGAGCCAG GAGCCTACGA CTGGTCCTCC ATAGTGCAAC ATGCATGTGA GCTGGAGGGA 
GACAGAAGCA GGTGGCAGGA GAAGGAAGCC AAGCTCAGAA GGACAGTCAC TCGTGTCCTG 
AGGTGTGATG TGACCAAGAC ACCCCCGCTG GGGTCAGCTC AGGTGCCTCT GGCTGACTGC 
GTGCTGACCT TTCTGGCCAT GGAGTGTGCC TGCCCTGATA TAGATACCTA CCGGGCAGCC 
TTGCGCAGAC TGGCCGGCCT GCTGAAACCA GGAGGGCACC TGGTGACCCT GGTTACTCTG 
CGCTTCCAGC ACTATATGGT GGGCCCCAAG AAGTTCTCTG GGGTCTACCT AGAGAAGGAG 
GTGGTGGAGA AGGCTATTCA AGATGCTGGC TGTCAGGTGC TGAAGTGCAA CTGCGTCTCC 
CTCAGCTACT CGGAGGCTTA CTGCTCCCAC GACGGTTTGT GCTTTGTGGT GGCCCGGAAG 
GGTCCCAGTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033375.1
CDS	8..802
Translation	MEGKVYIGGEDYEKEFTPKDYLTTYYSFHSGPVAEQEIVKFSLQNLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIVTDYTPQNLQELQKWLKKEPGAYDWSSIVQHACELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADCVLTFLAMECACPDIDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARKGPSA

Target ORF information:

RefSeq Version	NM_009349.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus indolethylamine N-methyltransferase (Inmt), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009349.3

ORF Insert Sequence:

ATGGAGGGCA AGGTATACAT AGGAGGTGAG GACTATGAAA AAGAGTTCAC TCCCAAAGAC 
TACCTGACCA CCTACTACAG CTTCCACTCT GGCCCTGTGG CAGAGCAGGA AATCGTAAAG 
TTTAGCCTGC AGAACCTCTA CCAGACCTTC TCTACAGGAG GTGTAGGGGG CGACGTCCTG 
ATCGACATTG GCTCTGGCCC TACCATCTAC CAGCTGCTTT CAGCATGCGA GGTCTTCCGG 
GAGATCATTG TCACTGACTA CACCCCGCAG AACCTGCAGG AGCTGCAGAA GTGGCTGAAG 
AAAGAGCCAG GAGCCTACGA CTGGTCCTCC ATAGTGCAAC ATGCATGTGA GCTGGAGGGA 
GACAGAAGCA GGTGGCAGGA GAAGGAAGCC AAGCTCAGAA GGACAGTCAC TCGTGTCCTG 
AGGTGTGATG TGACCAAGAC ACCCCCGCTG GGGTCAGCTC AGGTGCCTCT GGCTGACTGC 
GTGCTGACCT TTCTGGCCAT GGAGTGTGCC TGCCCTGATA TAGATACCTA CCGGGCAGCC 
TTGCGCAGAC TGGCCGGCCT GCTGAAACCA GGAGGGCACC TGGTGACCCT GGTTACTCTG 
CGCTTCCAGC ACTATATGGT GGGCCCCAAG AAGTTCTCTG GGGTCTACCT AGAGAAGGAG 
GTGGTGGAGA AGGCTATTCA AGATGCTGGC TGTCAGGTGC TGAAGTGCAA CTGCGTCTCC 
CTCAGCTACT CGGAGGCTTA CTGCTCCCAC GACGGTTTGT GCTTTGTGGT GGCCCGGAAG 
GGTCCCAGTG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.
Human molecular genetics28(13)2255-2270(2019 07)
Zieman AG,Poll BG,Ma J,Coulombe PA

Bmp4 from the optic vesicle specifies murine retina formation.
Developmental biology402(1)119-26(2015 Jun)
Huang J,Liu Y,Oltean A,Beebe DC

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
eLife3e03613(2014 Sep)
Alpern D,Langer D,Ballester B,Le Gras S,Romier C,Mengus G,Davidson I

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.
PloS one8(3)e58511(2013)
Im SK,Jeong H,Jeong HW,Kim KT,Hwang D,Ikegami M,Kong YY

Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N,N'-dimethyltryptamine forming enzyme, indole-N-methyl transferase.
Neuroscience20660-8(2012 Mar)
Mavlyutov TA,Epstein ML,Liu P,Verbny YI,Ziskind-Conhaim L,Ruoho AE